Pulmonary microvascular fracture in a patient with acute respiratory distress syndrome.

Abstract:

OBJECTIVE:To present electron micrographs of lung tissue obtained from a patient exposed to high ventilatory pressures in the context of pulmonary dysfunction and pulmonary hypertension. DESIGN:Case report. SETTING:Adult intensive care unit of a university-affiliated teaching hospital. PATIENTS:A patient exposed to high-pressure mechanical ventilation during support for acute respiratory distress syndrome; the acute respiratory distress syndrome in this case was secondary to septic shock. MEASUREMENTS AND MAIN RESULTS:Scanning electron micrographs of lung tissue, focusing on the internal alveolar surfaces. FINDINGS:Multiple gross disruptions of the alveolar walls, suggestive of stress fractures. CONCLUSION:High-pressure mechanical ventilation may promote fracturing of the alveolar blood:airspace barrier.

journal_name

Crit Care Med

journal_title

Critical care medicine

authors

Hotchkiss JR,Simonson DA,Marek DJ,Marini JJ,Dries DJ

doi

10.1097/00003246-200210000-00030

subject

Has Abstract

pub_date

2002-10-01 00:00:00

pages

2368-70

issue

10

eissn

0090-3493

issn

1530-0293

journal_volume

30

pub_type

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