A prospective study of the impact of patient preferences on life-sustaining treatment and hospital cost.

abstract：OBJECTIVES:To evaluate the timing of foregoing life-sustaining treatments in patients enrolled in a sepsis trial and to determine their influence on patient outcome and trial results. DESIGN:Subset of patients in a prospective, randomized, double-blind, placebo-controlled study. SETTING:Twenty-three academic medical ...

journal_title：Critical care medicine

authors： Sprung CL,Eidelman LA,Pizov R,Fisher CJ Jr,Ziegler EJ,Sadoff JC,Straube RC,McCloskey RV

更新日期：1997-03-01 00:00:00

abstract：OBJECTIVE:To examine the efficacy and safety of proton pump inhibitors in comparison with histamine-2 receptor antagonists for stress-related upper gastrointestinal bleeding prophylaxis among critical care patients. DATA SOURCES:PubMed, EMBASE, Cochrane Library, and ClinicalTrials.gov. STUDY SELECTION:Randomized, con...

journal_title：Critical care medicine

authors： Lin PC,Chang CH,Hsu PI,Tseng PL,Huang YB

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:Therapeutic hypothermia in the ICU requires mechanical ventilation and sedation. Hypothermia reduces the metabolism of commonly used IV sedatives. The use of long-acting sedative agents may confound neurologic assessment. Volatile anesthetics have been reported to provide protection against ischemia-reperfusi...

journal_title：Critical care medicine

authors： Hellström J,Öwall A,Martling CR,Sackey PV

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVES:Extracorporeal membrane oxygenation is used to stabilize severe cardiocirculatory and/or respiratory failure. However, extracorporeal membrane oxygenation is associated with a coagulopathy characterized by thromboembolic and hemorrhagic complications. This study aimed to characterize the pathomechanism of th...

journal_title：Critical care medicine

authors： Granja T,Hohenstein K,Schüssel P,Fischer C,Prüfer T,Schibilsky D,Wendel HP,Jaschonek K,Serna-Higuita L,Schlensak C,Häberle H,Rosenberger P,Straub A

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVES:To assess trends in the use of extracorporeal membrane oxygenation for poisoning in the United States. DESIGN:Retrospective cohort study. SETTING:The National Poison Data System, the databased owned and managed by the American Association of Poison Control Centers, the organization that supports and accred...

journal_title：Critical care medicine

authors： Cole JB,Olives TD,Ulici A,Litell JM,Bangh SA,Arens AM,Puskarich MA,Prekker ME

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVE:In children, like in adults, tracheal intubation is a painful procedure that may induce hypertension, tachycardia, and other undesirable hemodynamic disorders. Although premature neonates are very sensitive to pain and vulnerable to its long-term effects, the need for sedation before tracheal intubation is st...

journal_title：Critical care medicine

authors： Simon L,Trifa M,Mokhtari M,Hamza J,Treluyer JM

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVES:In this study, we hypothesized that coronavirus disease 2019 patients exhibit sublingual microcirculatory alterations caused by inflammation, coagulopathy, and hypoxemia. DESIGN:Multicenter case-controlled study. SETTING:Two ICUs in The Netherlands and one in Switzerland. PATIENTS:Thirty-four critically i...

journal_title：Critical care medicine

authors： Favaron E,Ince C,Hilty MP,Ergin B,van der Zee P,Uz Z,Wendel Garcia PD,Hofmaenner DA,Acevedo CT,van Boven WJ,Akin S,Gommers D,Endeman H

更新日期：2021-01-07 00:00:00

abstract：OBJECTIVE:To discuss the potential therapeutic value of intraluminal oxygenation of the gut in critical illness. DATA SOURCES:Relevant articles published in the English language literature. STUDY SELECTION:No special study has been carried out for the present presentation. DATA EXTRACTION:Information from the litera...

journal_title：Critical care medicine

authors： Haglund U

更新日期：1993-02-01 00:00:00

abstract：:Prolonged therapeutic paralysis with pancuronium is commonly used in ICUs to facilitate mechanical ventilation of patients with respiratory failure. Sedation is usually given concomitantly to reduce patient discomfort, but assessment of its adequacy is made difficult by the paralysis. We recently cared for a former IC...

journal_title：Critical care medicine

authors： Parker MM,Schubert W,Shelhamer JH,Parrillo JE

更新日期：1984-01-01 00:00:00

abstract：OBJECTIVES:To determine if prior total body hyperthermia protected against subsequent acute ileitis induced by the cytotoxic lectin, ricin, in rats. The time course of heat shock mRNA and protein expression in the ileum was determined. The effects of heat stress on small intestinal mucosal integrity, arachidonic acid m...

journal_title：Critical care medicine

authors： Stojadinovic A,Kiang J,Goldhill J,Matin D,Smallridge R,Galloway R,Shea-Donohue T

更新日期：1997-02-01 00:00:00

abstract：OBJECTIVES:The emergency department is an important venue for initial sepsis recognition and care. We sought to determine contemporary estimates of the epidemiology of U.S. emergency department visits for sepsis. DESIGN:Analysis of data from the National Hospital Ambulatory Medical Care Survey. SETTING:U.S. emergency...

journal_title：Critical care medicine

authors： Wang HE,Jones AR,Donnelly JP

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVES:To identify and appraise articles describing criteria used to prioritize or withhold a critical care admission. DATA SOURCES:PubMed, Embase, Medline, EBM Reviews, and CINAHL Complete databases. Gray literature searches and a manual review of references were also performed. Preferred Reporting Items for Syst...

journal_title：Critical care medicine

authors： Dahine J,Hébert PC,Ziegler D,Chenail N,Ferrari N,Hébert R

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:To estimate the prevalence of, the risk factors associated with, and the outcome of tracheostomy in a heterogeneous population of mechanically ventilated patients. DESIGN:Prospective, observational cohort study. SETTING:A total of 361 intensive care units from 12 countries. PATIENTS:A cohort of 5,081 patie...

journal_title：Critical care medicine

authors： Frutos-Vivar F,Esteban A,Apezteguía C,Anzueto A,Nightingale P,González M,Soto L,Rodrigo C,Raad J,David CM,Matamis D,D' Empaire G,International Mechanical Ventilation Study Group.

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVES:We examined recommendations within critical care guidelines to describe the pairing patterns for strength of recommendation and quality of evidence. We further identified recommendations where the reported strength of recommendation was strong while the reported quality of evidence was not high/moderate and ...

journal_title：Critical care medicine

authors： Sims CR,Warner MA,Stelfox HT,Hyder JA

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVES:Evaluate clinicians' sentiments about participating in cardiac arrest resuscitations and identify factors associated with confidence in resuscitation of cardiac arrest. DESIGN:Electronic survey. SETTING:Twenty-one hospitals in Utah and Idaho. SUBJECTS:All attending physicians, residents, and nurses in a m...

journal_title：Critical care medicine

authors： Peltan ID,Poll J,Sorensen J,Guidry D,Chandler M,Beninati W,Brown SM

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVE:To review the history and development of critical care nurses, the supply and demand issues related to critical care nursing, critical care nursing's contribution to patient outcomes, and recommendations to ensure a steady and strong workforce. DATA SOURCE AND SELECTION:Information presented in this article ...

journal_title：Critical care medicine

authors： Robnett MK

更新日期：2006-03-01 00:00:00

abstract：OBJECTIVES:Studies have shown contradicting results on the association of nursing workload and mortality. Most of these studies expressed workload as patients per nurse ratios; however, this does not take into account that some patients require more nursing time than others. Nursing time can be quantified by tools like...

journal_title：Critical care medicine

authors： Margadant C,Wortel S,Hoogendoorn M,Bosman R,Spijkstra JJ,Brinkman S,de Keizer N

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVES:Mild decrease in core temperature (therapeutic hypothermia) provides lasting neuroprotection following cardiac arrest or cerebral ischemia. However, current methods for producing therapeutic hypothermia trigger a cold-defense response that must be countered by sedatives, muscle paralytics, and mechanical ven...

journal_title：Critical care medicine

authors： Feketa VV,Zhang Y,Cao Z,Balasubramanian A,Flores CM,Player MR,Marrelli SP

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVE:To study the effects of high-dose epinephrine, compared with standard-dose epinephrine, on the dynamics of superficial cortical cerebral blood flow as well as global cerebral oxygenation during experimental cardiopulmonary resuscitation. We hypothesized that high-dose epinephrine might be unable to improve ce...

journal_title：Critical care medicine

authors： Gedeborg R,Silander HC,Ronne-Engström E,Rubertsson S,Wiklund L

更新日期：2000-05-01 00:00:00

abstract：OBJECTIVES:To investigate pharmacokinetics and metabolism of sodium citrate in critically ill patients. To determine the risk of citrate accumulation in the setting of liver dysfunction (cirrhosis, hepatorenal syndrome). DESIGN:Prospective cohort study. SETTING:Intensive Care Unit, Department of Medicine IV, Universi...

journal_title：Critical care medicine

authors： Kramer L,Bauer E,Joukhadar C,Strobl W,Gendo A,Madl C,Gangl A

更新日期：2003-10-01 00:00:00

abstract：:The clearance of amikacin during hemodialysis (HD) was determined in eight critically ill patients. The dialysis period averaged 3.4 h with a blood flow of 200 ml/min. The average amikacin clearance between dialysis was 7.30 +/- 4.78 (SD) ml/min which increased to 37.5 +/- 8.01 ml/min during dialysis. The average seru...

journal_title：Critical care medicine

authors： Armstrong DK,Hodgman T,Visconti JA,Reilley TE,Garner WL,Dasta JF

更新日期：1988-05-01 00:00:00

abstract：OBJECTIVES:Acute hemolysis is associated with organ damage, inflammation, and impaired vascular function. Stimulation of the cholecystokinin-1 receptor-dependent vagal anti-inflammatory reflex with lipid-rich enteral nutrition was demonstrated to prevent tissue damage and attenuate inflammation. This study investigates...

journal_title：Critical care medicine

authors： de Haan JJ,Windsant IV,Lubbers T,Hanssen SJ,Hadfoune M,Prinzen FW,Greve JW,Buurman WA

更新日期：2013-11-01 00:00:00

abstract：:Reproducibility of thermal-dye extravascular lung water (EVLW) estimation by a lung water computer was studied by performing ten consecutive measurements in 45 critically ill patients. EVLW ranged over a wide spectrum from 187 to 1163 ml (2.4 to 18.6 ml/kg). The mean coefficient of variation of ten consecutive measure...

journal_title：Critical care medicine

authors： Laggner AN,Lenz K,Druml W,Kleinberger G

更新日期：1987-06-01 00:00:00

abstract：OBJECTIVE:To evaluate the clinical utility of right ventricular end-diastolic volume index (RVEDVI) and pulmonary artery occlusion pressure (PAOP) as measures of preload status in patients with acute respiratory failure receiving treatment with positive end-expiratory pressure. DESIGN:Prospective, cohort study. SETTI...

journal_title：Critical care medicine

authors： Cheatham ML,Nelson LD,Chang MC,Safcsak K

更新日期：1998-11-01 00:00:00

abstract：OBJECTIVES:To determine whether glucose utilization and metabolic substrate (glucose and fat) oxidation could be manipulated in patients with secondary multiple organ dysfunction syndrome. DESIGN:Prospective study. SETTING:Intensive care units (ICU) of two university hospitals. PATIENTS:Eight adults free of hepatic ...

journal_title：Critical care medicine

authors： Arnold J,Campbell IT,Hipkin LJ,Keegan M,Jenkins S,O'Sullivan E,Chadwick S

更新日期：1995-01-01 00:00:00

abstract：OBJECTIVES:To confirm early, marked decrease in plasma selenium concentrations in patients admitted to a surgical and medical intensive care unit (ICU), and to study this decrease according to the presence or absence of systemic inflammatory response syndrome (SIRS), sepsis, or direct ischemia-reperfusion. DESIGN:Pros...

journal_title：Critical care medicine

authors： Forceville X,Vitoux D,Gauzit R,Combes A,Lahilaire P,Chappuis P

更新日期：1998-09-01 00:00:00

abstract：OBJECTIVES:Fever is common and associated with increased mortality among patients admitted to adult ICUs, yet recent literature suggests that the incidence of fever may be decreasing. The objective of this study was to determine whether the incidence of fever in adult ICUs changed over time and the factors responsible ...

journal_title：Critical care medicine

authors： Niven DJ,Stelfox HT,Shahpori R,Laupland KB

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that the lectin-like domain of tumor necrosis factor, mimicked by the TIP peptide, can improve lung function after unilateral orthotopic lung isotransplantation. Because of a lack of a specific treatment for ischemia reperfusion-mediated lung injury, accompanied by a disrupted barrier i...

journal_title：Critical care medicine

authors： Hamacher J,Stammberger U,Roux J,Kumar S,Yang G,Xiong C,Schmid RA,Fakin RM,Chakraborty T,Hossain HM,Pittet JF,Wendel A,Black SM,Lucas R

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:Although hepatic cytochrome P-450 protein concentrations are altered following endotoxin shock, changes in P-450 isoforms in sepsis have not been fully investigated. The aim of this study was to determine whether the major P-450 isoform in rat liver (i.e., CYP1A2) is down-regulated during the progression of s...

journal_title：Critical care medicine

authors： Crawford JH,Yang S,Zhou M,Simms HH,Wang P

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVE:To investigate the association of collaboration between intensive care unit (ICU) physicians and nurses and patient outcome. DESIGN:Prospective, descriptive, correlational study using self-report instruments. SETTINGS:A community teaching hospital medical ICU, a university teaching hospital surgical ICU, an...

journal_title：Critical care medicine

authors： Baggs JG,Schmitt MH,Mushlin AI,Mitchell PH,Eldredge DH,Oakes D,Hutson AD

更新日期：1999-09-01 00:00:00