Guidelines for resident physician training in critical care medicine. Guidelines/Practice Parameters Committee, American College of Critical Care Medicine of the Society of Critical Care Medicine.

abstract：OBJECTIVE:Sepsis is a frequent cause of admission, but incidence rates based on administrative data have previously produced large differences in estimates. The aim of the study was to estimate the incidence of community-acquired sepsis based on patients' symptoms and clinical findings at arrival to the hospital. DESI...

journal_title：Critical care medicine

authors： Henriksen DP,Laursen CB,Jensen TG,Hallas J,Pedersen C,Lassen AT

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVES:To evaluate the internal consistency, validity, responsiveness, and minimal important difference of the Functional Status Score for the ICU, a physical function measure designed for the ICU. DESIGN:Clinimetric analysis. SETTINGS:Five international datasets from the United States, Australia, and Brazil. PA...

journal_title：Critical care medicine

authors： Huang M,Chan KS,Zanni JM,Parry SM,Neto SG,Neto JA,da Silva VZ,Kho ME,Needham DM

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:To measure exhaled nitric oxide (NO) and compare it with lung function after cardiopulmonary bypass (CPB) in adult patients. Pulmonary dysfunction is sometimes observed after CPB. Impaired production of NO may account for this dysfunction. DESIGN:Prospective, single-center, observational study. SETTING:Univ...

journal_title：Critical care medicine

authors： Ishibe Y,Liu R,Hirosawa J,Kawamura K,Yamasaki K,Saito N

更新日期：2000-12-01 00:00:00

abstract：OBJECTIVES:We sought to review findings from recent literature on the postresuscitation care of cardiac arrest patients using therapeutic hypothermia as part of nontrial treatment. DESIGN:Literature review. SETTING:Hospital-based environment. SUBJECTS:Patients initially resuscitated from cardiac arrest who underwent...

journal_title：Critical care medicine

authors： Sagalyn E,Band RA,Gaieski DF,Abella BS

更新日期：2009-07-01 00:00:00

abstract：:Doppler ultrasound was used to study cerebral hemodynamics in the pericallosal artery of 21 newborn infants undergoing extracorporeal membrane oxygenation (ECMO) for intractable respiratory failure. Cerebral blood flow velocity waveforms were obtained pre-ECMO, after every major change in cardiopulmonary bypass flow d...

journal_title：Critical care medicine

authors： van de Bor M,Walther FJ,Gangitano ES,Snyder JR

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVES:Guidelines recommend offering family members of critically ill patients the option to attend interdisciplinary team rounds as a way to improve communication and satisfaction. Uncertainty remains around the benefits and risks. DESIGN:We conducted an observational study to describe family participation in ICU...

journal_title：Critical care medicine

authors： Au SS,Roze des Ordons AL,Parsons Leigh J,Soo A,Guienguere S,Bagshaw SM,Stelfox HT

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:To evaluate the action of high-dose epinephrine by measuring simultaneously its vasopressor and norepinephrine releasing effects in humans during cardiac arrest. DESIGN:A prospective study on consecutive patients admitted with cardiac arrest. SETTING:Emergency Department in a large, urban hospital. PATIENT...

journal_title：Critical care medicine

authors： Wortsman J,Paradis NA,Martin GB,Rivers EP,Goetting MG,Nowak RM,Cryer PE

更新日期：1993-05-01 00:00:00

abstract：OBJECTIVES:Targeted temperature management has been shown to improve survival with good neurological outcome in patients after out-of-hospital cardiac arrest. The optimal approach to inducing and maintaining targeted temperature management, however, remains uncertain. The objective of this study was to evaluate these p...

journal_title：Critical care medicine

authors： Lin S,Scales DC,Dorian P,Kiss A,Common MR,Brooks SC,Goodman SG,Salciccioli JD,Morrison LJ

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVES:In this systematic review and meta-analysis, we assessed whether a high CO2 gap predicts mortality in adult critically ill patients with circulatory shock. DATA SOURCES:A systematic search of MEDLINE and EMBASE electronic databases from inception to October 2019. STUDY SELECTION:Studies from adult (age ≥ 1...

journal_title：Critical care medicine

authors： Al Duhailib Z,Hegazy AF,Lalli R,Fiorini K,Priestap F,Iansavichene A,Slessarev M

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:Using a modification of the Bohr equation, single-breath carbon dioxide capnography is a noninvasive technology for calculating physiologic dead space (V(D)/V(T)). The objective of this study was to identify a minimal V(D)/V(T) value for predicting successful extubation from mechanical ventilation in pediatri...

journal_title：Critical care medicine

authors： Hubble CL,Gentile MA,Tripp DS,Craig DM,Meliones JN,Cheifetz IM

更新日期：2000-06-01 00:00:00

abstract：OBJECTIVE:To determine the association of pulmonary artery catheter (PAC) use with in-hospital mortality. DESIGN:Prospective, observational study. SETTING:The medical intensive care units (MICU) of two teaching hospitals. METHODS:The study included 751 adults who were admitted to the MICU, excluding those who stayed...

journal_title：Critical care medicine

authors： Afessa B,Spencer S,Khan W,LaGatta M,Bridges L,Freire AX

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVES:Although studies have indicated that adrenal insufficiency occurs after severe trauma and hemorrhagic shock, it remains controversial whether adrenal function is depressed during the late stage of polymicrobial sepsis. DESIGN:Prospective, controlled animal study. SETTING:A university research laboratory. ...

journal_title：Critical care medicine

authors： Koo DJ,Jackman D,Chaudry IH,Wang P

更新日期：2001-03-01 00:00:00

abstract：OBJECTIVE:The physicochemical approach, described by Stewart to investigate the acid-base balance, includes the strong ion gap (SIG), a quantitative measure of "unmeasured" anions, which strongly correlates to the corrected anion gap. The chemical nature of these anions is for the most part unknown. We hypothesized tha...

journal_title：Critical care medicine

authors： Moviat M,Terpstra AM,Ruitenbeek W,Kluijtmans LA,Pickkers P,van der Hoeven JG

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVES:Brain death induces a massive inflammatory response. However, the influence of this inflammatory response on organ procurement, transplantation, and recipient outcome is unknown. We describe the inflammatory response characteristics in brain-dead organ donors and examine associations with organ transplantati...

journal_title：Critical care medicine

authors： Murugan R,Venkataraman R,Wahed AS,Elder M,Hergenroeder G,Carter M,Madden NJ,Powner D,Kellum JA,HIDonOR Study Investigators.

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVE:Acute renal failure remains a major challenge in critical care medicine. Both neutrophils and chemokines have been proposed as key components in the development of acute renal failure. Although the Duffy antigen receptor for chemokines (DARC) is present in several tissues and a highly specific ligand for vari...

journal_title：Critical care medicine

authors： Zarbock A,Schmolke M,Bockhorn SG,Scharte M,Buschmann K,Ley K,Singbartl K

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVES:Palliative care is now recognized as an essential component of comprehensive care in serious illness that interferes with quality of life. We explored utilization of palliative care in spontaneous intracerebral hemorrhage at a population level using a large national database. DESIGN:Population based cross-s...

journal_title：Critical care medicine

authors： Murthy SB,Moradiya Y,Hanley DF,Ziai WC

更新日期：2016-03-01 00:00:00

abstract：:Cerebral arteriovenous differences in oxygen content [C(a-v)O2] and glucose content [C(a-v)gluc] were used to predict outcome in 20 patients who remained comatose after resuscitation for cardiopulmonary arrest. Cerebral prognosis was good when C(a-v)O2 values were greater than 1.8 mMol/L and the oxygen glucose index (...

journal_title：Critical care medicine

authors： Ducassé JL,Marc-Vergnes JP,Cathala B,Genestal M,Lareng L

更新日期：1984-10-01 00:00:00

abstract：:The effect of positive-pressure ventilation (PPV) with PEEP on the release of alpha-atrial natriuretic peptide (ANP) was investigated in both humans and an experimental model. In the human study, systemic artery blood samples from 22 critically ill patients were analyzed for ANP. Seventeen of these patients received P...

journal_title：Critical care medicine

authors： Teba L,Dedhia HV,Schiebel FG,Blehschmidt NG,Lindner WJ

更新日期：1990-08-01 00:00:00

abstract：OBJECTIVES:Hepatic ischemia-reperfusion is a major clinical problem with limited treatment options. The pathophysiology of hepatic ischemia-reperfusion is characterized by mitochondrial dysfunction and cellular energy deficits. Sirtuin 1 is an energy-sensing enzyme known to modulate mitochondrial biogenesis. We hypothe...

journal_title：Critical care medicine

authors： Khader A,Yang WL,Godwin A,Prince JM,Nicastro JM,Coppa GF,Wang P

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:To determine the financial impact of a sepsis protocol designed for use in the emergency department. DESIGN:Retrospective analysis of a before-after study testing the implications of sepsis protocol. SETTING:Academic, tertiary care hospital in the United States. PATIENTS:Persons with septic shock presentin...

journal_title：Critical care medicine

authors： Shorr AF,Micek ST,Jackson WL Jr,Kollef MH

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:Tea has been around for centuries, and its medicinal properties have been purported in the literature but never fully confirmed. Interleukin-8 is a principle neutrophil chemoattractant and activator in humans. We determined the effects of theaflavin, a black tea-derived polyphenol, on tumor necrosis factor-al...

journal_title：Critical care medicine

authors： Aneja R,Odoms K,Denenberg AG,Wong HR

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND AND METHODS:The purpose of this study was twofold: the development of a chronic model of leukocyte-mediated pulmonary injury and the evaluation of the protective effects of methylprednisolone. Rabbits were inoculated ip with zymosan. Blood gases and circulating leukocytes were evaluated. Survivors were kille...

journal_title：Critical care medicine

authors： Chiara O,Giomarelli PP,Borrelli E,Casini A,Segala M,Grossi A

更新日期：1991-02-01 00:00:00

abstract：OBJECTIVES:Radiographic criteria for acute respiratory distress syndrome have been criticized for poor reliability. Our objective was to test an educational intervention to improve the radiographic identification of acute respiratory distress syndrome by participants in the Large Observational Study to Understand the G...

journal_title：Critical care medicine

authors： Goddard SL,Rubenfeld GD,Manoharan V,Dev SP,Laffey J,Bellani G,Pham T,Fan E

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:Because of their beneficial effects in patients with hemorrhagic shock and multiple-system trauma, hypertonic saline solutions are increasingly being used perioperatively for volume resuscitation. Although the anti-edema effects of hypertonic saline on brain are well documented in a variety of brain injury pa...

journal_title：Critical care medicine

authors： Toung TJ,Chen CH,Lin C,Bhardwaj A

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND AND METHODS:To determine the effects of reduced cerebral perfusion pressures produced by hemorrhage alone or in combination with intracranial hypertension on thromboxane A2 (TxA2) production, we undertook a randomized study in 38 anesthetized, mongrel dogs. Animals were subjected to 30 mins of hemorrhagic sh...

journal_title：Critical care medicine

authors： Kong DL,Prough DS,Whitley JM,Taylor C,Vines S,Deal DD,DeWitt DS

更新日期：1991-04-01 00:00:00

abstract：:The effect of positive end-expiratory pressure (PEEP) on PaO2 during collapse of a single pulmonary lobe was investigated in seven dogs. Increasing PEEP to the ventilated region of lung increased the proportion of cardiac output flowing to the collapsed lobe and decreased PaO2 and pH. PaCO2 increased at the onset of l...

journal_title：Critical care medicine

authors： Sánchez De León R,Orchard C,Sykes K,Brajkovich I

更新日期：1985-05-01 00:00:00

abstract：OBJECTIVES:Hospitals use a variety of strategies to maximize the availability of limited ICU beds. Boarding, which involves assigning patients to an open bed in a different subspecialty ICU, is one such practice employed when ICU occupancy levels are high, and beds in a particular unit are unavailable. Boarding disrupt...

journal_title：Critical care medicine

authors： Stretch R,Della Penna N,Celi LA,Landon BE

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:To document the effects of propofol on the hemodynamic and inflammatory responses to endotoxemia in an animal model. DESIGN:Randomized, prospective laboratory study. SETTING:University experimental laboratory. SUBJECTS:Thirty-two male rats. INTERVENTIONS:The animals were randomly assigned to one of four g...

journal_title：Critical care medicine

authors： Taniguchi T,Yamamoto K,Ohmoto N,Ohta K,Kobayashi T

更新日期：2000-04-01 00:00:00

abstract：:Critical care clinicians no longer consider family members as visitors in the intensive care unit. Family-centered care has emerged from the results of qualitative and quantitative studies evaluating the specific needs of families of patients dying in the intensive care unit. In addition, interventional studies have e...

journal_title：Critical care medicine

authors： Lautrette A,Ciroldi M,Ksibi H,Azoulay E

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVE:To investigate the mechanism by which methylprednisolone protects the liver from hypoxia-induced injury. DESIGN:Prospective control study using the isolated rat liver. SETTING:Animal research facility. SUBJECTS:Male, fasted, pathogen-free Sprague-Dawley rats. INTERVENTIONS:Low-flow hypoxia was produced by...

journal_title：Critical care medicine

authors： Motoyama S,Saito S,Minamiya Y,Saito R,Nakamura M,Okuyama M,Imano H,Ogawa J

更新日期：2003-05-01 00:00:00