Therapeutic hypothermia after cardiac arrest in clinical practice: review and compilation of recent experiences.

abstract：OBJECTIVE:To investigate the effect of norepinephrine on static (right atrial pressure, pulmonary artery occlusion pressure ) and dynamic (pulse pressure variation and arterial systolic pressure variation) preload indicators in experimental hemorrhagic shock. DESIGN:Prospective controlled experimental study. SETTING:...

journal_title：Critical care medicine

authors： Nouira S,Elatrous S,Dimassi S,Besbes L,Boukef R,Mohamed B,Abroug F

更新日期：2005-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the in vivo production of prostacyclin and thromboxane A2 during the initial phase of experimental fat embolism as assessed, respectively, by determinations of urine 2,3-dinor-6-ketoprostaglandin F1alpha and 11-dehydrothromboxane B2 excretion. DESIGN:Randomized, controlled trial. SETTING:Animal ...

journal_title：Critical care medicine

authors： Rautanen M,Gullichsen E,Riutta A,Kuttila K,Mucha I,Nelimarkka O,Niinikoski J

更新日期：1997-07-01 00:00:00

abstract：OBJECTIVES:To study the relation between nitrite, nitrate, nitrotyrosine, and nitrosothiols as NO indices in human septic shock. DESIGN:A prospective clinical study. SETTING:Intensive care units in a university hospital and a central county hospital. PATIENTS:Sixteen patients admitted for septic shock. Nine healthy ...

journal_title：Critical care medicine

authors： Strand OA,Leone A,Giercksky KE,Kirkebøen KA

更新日期：2000-08-01 00:00:00

abstract：OBJECTIVE:Cerebral perfusion pressure<40 mm Hg following pediatric traumatic brain injury has been associated with increased mortality independent of age, and current guidelines recommend maintaining cerebral perfusion pressure between 40 mm Hg-60 mm Hg. Although adult traumatic brain injury studies have observed an in...

journal_title：Critical care medicine

authors： Friess SH,Smith C,Kilbaugh TJ,Frangos SG,Ralston J,Helfaer MA,Margulies SS

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:To investigate the impact of prophylactic continuous lateral rotation therapy on the prevalence of ventilator-associated pneumonia, duration of mechanical ventilation, length of stay, and mortality in critically ill medical patients. DESIGN:Prospective, randomized, clinical study. SETTING:Three medical inte...

journal_title：Critical care medicine

authors： Staudinger T,Bojic A,Holzinger U,Meyer B,Rohwer M,Mallner F,Schellongowski P,Robak O,Laczika K,Frass M,Locker GJ

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:There is evidence to suggest that anemia after severe traumatic brain injury (sTBI) is detrimental. However, there is a paucity of evidence supporting the use of transfusion of packed red blood cells in patients with sTBI. To understand the acute effect of packed red blood cell transfusion on cerebral oxygena...

journal_title：Critical care medicine

authors： Zygun DA,Nortje J,Hutchinson PJ,Timofeev I,Menon DK,Gupta AK

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVE:The flow rate of a liquid drainage from the lungs is limited because of the elastic nature of the airways. This study was designed to clarify the relationship between intrapulmonary liquid volume and the development of the flow limitation or choked flow phenomenon as a function of expiratory flow rate during ...

journal_title：Critical care medicine

authors： Baba Y,Brant D,Brah SS,Grotberg J,Bartlett RH,Hirschl RB

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:To review recent advances in the use of transforming growth factor (TGF)-beta in acute lung injury and to apply this knowledge to understanding the pathophysiology of this syndrome. DATA SOURCES AND STUDY SELECTION:Published research and review articles in the English language related to the role of TGF-beta...

journal_title：Critical care medicine

authors： Dhainaut JF,Charpentier J,Chiche JD

更新日期：2003-04-01 00:00:00

abstract：:In order to examine the prognostic value of pulmonary arterial hypertension (PAH) in patients with moderate and severe acute respiratory failure (ARF), 225 patients with ARF who had been treated with mechanical ventilation and admitted to our ICU during a 3-yr period (January, 1983 to January, 1986) were prospectively...

journal_title：Critical care medicine

authors： Villar J,Blazquez MA,Lubillo S,Quintana J,Manzano JL

更新日期：1989-06-01 00:00:00

abstract：OBJECTIVE:To quantify glucose balance related to continuous arteriovenous hemofiltration (CAVH) when a glucose-rich replacement fluid is used for the plasma ultrafiltrate removed. DESIGN:Prospective, nonintervention study. SETTING:Medical/surgical and cardiac surgical intensive care units of a university hospital. P...

journal_title：Critical care medicine

authors： Monaghan R,Watters JM,Clancey SM,Moulton SB,Rabin EZ

更新日期：1993-08-01 00:00:00

abstract：OBJECTIVE:We hypothesized that the extent of injury and release of xanthine oxidase, an oxidant generator, into the circulation would be less in normal-flow hypoxia-reoxygenation than in equal duration no-flow ischemia-reperfusion. DESIGN:Randomized study. SETTING:University-based animal research facility. SUBJECTS:...

journal_title：Critical care medicine

authors： Tan S,Yokoyama Y,Wang Z,Zhou F,Nielsen V,Murdoch AD,Adams C,Parks DA

更新日期：1998-06-01 00:00:00

abstract：OBJECTIVE:To review trial design issues related to control groups. DESIGN:Review of the literature with specific reference to critical care trials. MAIN RESULTS AND CONCLUSIONS:Performing randomized controlled trials in the critical care setting presents specific problems: studies include patients with rapidly lethal...

journal_title：Critical care medicine

authors： Takala J

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVES:Increasing time to mechanical ventilation and high-flow nasal cannula use may be associated with mortality in coronavirus disease 2019. We examined the impact of time to intubation and use of high-flow nasal cannula on clinical outcomes in patients with coronavirus disease 2019. DESIGN:Retrospective cohort ...

journal_title：Critical care medicine

authors： Hernandez-Romieu AC,Adelman MW,Hockstein MA,Robichaux CJ,Edwards JA,Fazio JC,Blum JM,Jabaley CS,Caridi-Scheible M,Martin GS,Murphy DJ,Auld SC,Emory COVID-19 Quality and Clinical Research Collaborative.

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVES:Randomized trials have suggested that hypertonic saline solutions may be superior to mannitol for the treatment of elevated intracranial pressure, but their impact on clinical practice has been limited, partly by their small size. We therefore combined their findings in a meta-analysis. DATA SOURCES:We sear...

journal_title：Critical care medicine

authors： Kamel H,Navi BB,Nakagawa K,Hemphill JC 3rd,Ko NU

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVES:Despite having dysregulated iron metabolism, critically ill patients may receive exogenous iron for the treatment of anemia. Iron is associated with increased tissue apoptosis and may facilitate bacterial growth. We hypothesized that exogenous iron administration given after the onset of sepsis would lead to...

journal_title：Critical care medicine

authors： Javadi P,Buchman TG,Stromberg PE,Husain KD,Dunne WM,Woolsey CA,Turnbull IR,Hotchkiss RS,Karl IE,Coopersmith CM

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVE:To determine the role of serum albumin concentration as a predictor of mechanical ventilation dependency. DESIGN:Prospective, observation trial. SETTING:Multidisciplinary intensive care unit (ICU) in a university hospital. PATIENTS:One hundred forty-five consecutive patients who required mechanical ventila...

journal_title：Critical care medicine

authors： Sapijaszko MJ,Brant R,Sandham D,Berthiaume Y

更新日期：1996-04-01 00:00:00

abstract：OBJECTIVE:Anecdotal reports suggest that propofol (Diprivan) may stimulate mucus hypersecretion in patients without pulmonary disease. The purpose of this study was to evaluate the effect of methohexital or propofol anesthesia on the physical and transport properties of airway mucus in spontaneously breathing dogs. DE...

journal_title：Critical care medicine

authors： Padda GS,Kishioka C,Rubin BK

更新日期：2001-05-01 00:00:00

abstract：OBJECTIVE:To determine whether extreme obesity (morbid obesity; body mass index > or =40 kg/m(2)) is an independent risk factor for death among critically ill patients; this objective is most salient in the subset of patients who sustain a prolonged intensive care unit stay during which the burdens of care imposed by o...

journal_title：Critical care medicine

authors： Nasraway SA Jr,Albert M,Donnelly AM,Ruthazer R,Shikora SA,Saltzman E

更新日期：2006-04-01 00:00:00

abstract：OBJECTIVES:Although discussing a prognosis is a duty of physicians caring for critically ill patients, little is known about surrogate decision-makers' beliefs about physicians' ability to prognosticate. We sought to determine: 1) surrogates' beliefs about whether physicians can accurately prognosticate for critically ...

journal_title：Critical care medicine

authors： Zier LS,Burack JH,Micco G,Chipman AK,Frank JA,Luce JM,White DB

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVE:To compare the ability of two methods--Acute Physiology and Chronic Health Evaluation (APACHE II) and Mortality Prediction Model (MPM)--to predict hospital outcome for a large group of intensive care patients from Britain and Ireland. DESIGN:Prospective, multicenter, cohort study. SETTING:Twenty-six general...

journal_title：Critical care medicine

authors： Rowan KM,Kerr JH,Major E,McPherson K,Short A,Vessey MP

更新日期：1994-09-01 00:00:00

abstract：OBJECTIVES:To measure pulmonary capillary pressure and pulmonary artery occlusion pressures both during control conditions and during acute lung injury and to evaluate the effects of inotropic therapy and volume loading on these measurements after lung injury. DESIGN:Prospective, randomized, controlled laboratory tria...

journal_title：Critical care medicine

authors： Pellett AA,Lord KC,Champagne MS,deBoisblanc BP,Johnson RW,Levitzky MG

更新日期：2002-02-01 00:00:00

abstract：OBJECTIVES:Radial artery pressure is known to differ from central arterial pressure in normal patients (distal pulse amplification) and in the early postcardiopulmonary bypass period. The adequacy of the radial artery as a site for blood pressure monitoring in critically ill patients receiving high-dose vasopressors ha...

journal_title：Critical care medicine

authors： Dorman T,Breslow MJ,Lipsett PA,Rosenberg JM,Balser JR,Almog Y,Rosenfeld BA

更新日期：1998-10-01 00:00:00

abstract：OBJECTIVES:a) To investigate whether the patient work of breathing needed to trigger inspiration is affected by the type of ventilator delivering pressure-support ventilation for mechanically ventilated pediatric patients. b) To determine whether changes in oxygen consumption (VO2) trend with changes in work of breathi...

journal_title：Critical care medicine

authors： el-Khatib MF,Chatburn RL,Potts DL,Blumer JL,Smith PG

更新日期：1994-12-01 00:00:00

abstract：OBJECTIVE:To assess clinician perceptions of a machine learning-based early warning system to predict severe sepsis and septic shock (Early Warning System 2.0). DESIGN:Prospective observational study. SETTING:Tertiary teaching hospital in Philadelphia, PA. PATIENTS:Non-ICU admissions November-December 2016. INTERVE...

journal_title：Critical care medicine

authors： Ginestra JC,Giannini HM,Schweickert WD,Meadows L,Lynch MJ,Pavan K,Chivers CJ,Draugelis M,Donnelly PJ,Fuchs BD,Umscheid CA

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVE:To define the epidemiology of broad-spectrum cephalosporin-resistant gram-negative bacilli in intensive care units (ICUs) during a nonoutbreak period, including the prevalence, the risk factors for colonization, the frequency of acquisition, and the rate of infection. DESIGN:Prospective cohort study. SETTIN...

journal_title：Critical care medicine

authors： D'Agata EM,Venkataraman L,DeGirolami P,Burke P,Eliopoulos GM,Karchmer AW,Samore MH

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND AND METHODS:Calcium-channel blockers may attenuate vasospasm after transient ischemia and improve organ blood flow after resuscitation. Our aim was to assess the effect of diltiazem on systemic oxygen delivery and consumption, hemodynamics, electroencephalogram (EEG), and organ blood flow after restoration o...

journal_title：Critical care medicine

authors： Lindner KH,Prengel AW,Ahnefeld FW,Ensinger H,Schürmann W

更新日期：1992-05-01 00:00:00

abstract：OBJECTIVE:To determine the occurrence rate of complications and mortality in patients with severe asthma requiring endotracheal intubation and mechanical ventilation. DESIGN:Retrospective review of medical records from September 1982 to July 1988. SETTING:Urban, teaching hospital serving primarily indigent patients. ...

journal_title：Critical care medicine

authors： Zimmerman JL,Dellinger RP,Shah AN,Taylor RW

更新日期：1993-11-01 00:00:00

abstract：OBJECTIVE:The purpose of this study is to: 1) describe a newly mechanism of blood flow to the brain during cardiopulmonary resuscitation using the impedance threshold device in a piglet model of cardiac arrest, and 2) describe the survival benefits in humans of applying all of the highly recommended changes in the 2005...

journal_title：Critical care medicine

authors： Aufderheide TP,Alexander C,Lick C,Myers B,Romig L,Vartanian L,Stothert J,McKnite S,Matsuura T,Yannopoulos D,Lurie K

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVE:To discuss a potential role for endothelial cell apoptosis in the pathogenesis of sepsis. DATA SOURCES:Studies published in biomedical journals and studies from the authors' laboratory. STUDY SELECTION:In vitro and in vivo studies of endothelial cell apoptosis in endotoxin and sepsis models. DATA EXTRACTIO...

journal_title：Critical care medicine

authors： Hotchkiss RS,Tinsley KW,Swanson PE,Karl IE

更新日期：2002-05-01 00:00:00

abstract：OBJECTIVE:To assess the effects of dopexamine on splanchnic blood flow and splanchnic oxygen uptake in septic patients. DESIGN:A prospective, controlled trial. SETTING:A ten-bed intensive care unit (ICU) in a university hospital. PATIENTS:Twelve patients with severe sepsis (according to the criteria of the 1992 Amer...

journal_title：Critical care medicine

authors： Meier-Hellmann A,Bredle DL,Specht M,Hannemann L,Reinhart K

更新日期：1999-10-01 00:00:00