Dopexamine increases splanchnic blood flow but decreases gastric mucosal pH in severe septic patients treated with dobutamine.

abstract：OBJECTIVE:Physiologic and pathologic comparison of two modes of assisted ventilation, nasal intermittent positive-pressure ventilation (NIPPV) and synchronized intermittent mandatory ventilation (SIMV), in spontaneously breathing term newborn piglets with saline lavage-induced lung injury. DESIGN:After inducing acute ...

journal_title：Critical care medicine

authors： Lampland AL,Meyers PA,Worwa CT,Swanson EC,Mammel MC

更新日期：2008-01-01 00:00:00

abstract：:Although systolic dysfunction of the left ventricle has been characterized in septic shock (SS) and sepsis without shock (SWS), diastolic abnormalities are less well characterized. Diastolic filling was determined using pulsed Doppler transmitral spectral tracings in 13 patients with SS, ten patients with SWS, and 33 ...

journal_title：Critical care medicine

authors： Jafri SM,Lavine S,Field BE,Bahorozian MT,Carlson RW

更新日期：1990-07-01 00:00:00

abstract：OBJECTIVES:Endovascular treatment for acute ischemic stroke with a large vessel occlusion was recently shown to be effective. We aimed to develop a score capable of predicting large vessel occlusion eligible for endovascular treatment in the early hospital management. DESIGN:Retrospective, cohort study. SETTING:Two t...

journal_title：Critical care medicine

authors： Vanacker P,Heldner MR,Amiguet M,Faouzi M,Cras P,Ntaios G,Arnold M,Mattle HP,Gralla J,Fischer U,Michel P

更新日期：2016-06-01 00:00:00

abstract：:It was found that, during 1974, it cost an average of $8842 ($12,909 in 1979) to care for a survivor of severe respiratory distress syndrome (RDS) who required mechanical ventilation in this ICU compared to $2448 ($3574 in 1979) for nonsurvivors. Death in 15 out of the 16 nonsurvivors was accompanied by grade III-IV i...

journal_title：Critical care medicine

authors： Shannon DC,Crone RK,Todres ID,Krishnamoorthy KS

更新日期：1981-02-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to examine whether anandamide, an endogenous cannabinoid receptor ligand, is involved in the pathogenesis of septic encephalopathy. DESIGN:Prospective, controlled study. SUBJECTS:Male Wistar rats (7 wks old) were randomly divided into four groups as follows: group 1, control (...

journal_title：Critical care medicine

authors： Kadoi Y,Hinohara H,Kunimoto F,Saito S,Goto F

更新日期：2005-11-01 00:00:00

abstract：OBJECTIVE AND DESIGN:To review and discuss selected literature, expert opinion, and conventional care of the hyperglycemic perioperative or critically ill patient. MAIN POINTS:Diabetes mellitus, the most commonly encountered perioperative endocrinopathy, continues to increase dramatically in prevalence. Diabetes is th...

journal_title：Critical care medicine

authors： Coursin DB,Connery LE,Ketzler JT

更新日期：2004-04-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that the hypocalcemia and hypoparathyroidism that follow severe burn injury are related to up-regulation of the parathyroid gland calcium-sensing receptor (CaR), which may reduce the set-point for suppression of circulating parathyroid hormone by blood calcium. DESIGN:A controlled but ...

journal_title：Critical care medicine

authors： Murphey ED,Chattopadhyay N,Bai M,Kifor O,Harper D,Traber DL,Hawkins HK,Brown EM,Klein GL

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:The 2003 global outbreak of severe acute respiratory syndrome (SARS) provided numerous challenges to the delivery of critical care. The Toronto critical care community has learned important lessons from SARS, which will help in preparation for future disease outbreaks. OBJECTIVES:The objectives of this stud...

journal_title：Critical care medicine

authors： Booth CM,Stewart TE

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:To determine whether a correlation exists between concentrations of intracellular and extracellular potassium and to determine the frequency of ventricular ectopy in patients after cardiac operations. DESIGN:Prospective, observational clinical evaluation. SETTING:Surgical-respiratory intensive care unit of ...

journal_title：Critical care medicine

authors： Johnson RG,Shafique T,Sirois C,Weintraub RM,Comunale ME

更新日期：1999-11-01 00:00:00

abstract：OBJECTIVE:To compare the scales and predictive power for hospital mortality of three recent multiple organ dysfunction scores. DESIGN:Prospective, observational, validation cohort study. SETTING:A ten-bed medical-surgical intensive care unit in a Finnish tertiary care hospital. PATIENTS:Among the 591 consecutive pat...

journal_title：Critical care medicine

authors： Pettilä V,Pettilä M,Sarna S,Voutilainen P,Takkunen O

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVE:The genetic background of hypertensive crisis is unknown. We examined the association of polymorphisms in genes involved in the renin-angiotensin-aldosterone-system with hypertensive crisis. DESIGN:Population-based case-control study. SETTING:Emergency department at a tertiary care university hospital. PAT...

journal_title：Critical care medicine

authors： Sunder-Plassmann G,Kittler H,Eberle C,Hirschl MM,Woisetschläger C,Derhaschnig U,Laggner AN,Hörl WH,Födinger M

更新日期：2002-10-01 00:00:00

abstract：OBJECTIVES:Procalcitonin (PCT) has been described as an early, discriminating marker of bacteria-associated sepsis in patients. However, little is known of its source and actions, in part because no appropriate animal models have been available. We tested the hypothesis that plasma PCT increases during various pathophy...

journal_title：Critical care medicine

authors： Redl H,Schlag G,Tögel E,Assicot M,Bohuon C

更新日期：2000-11-01 00:00:00

abstract：:Right ventricular size and contractility were evaluated using two-dimensional echocardiography during the first days of respiratory support in 23 patients requiring mechanical ventilation for acute respiratory failure. Nine patients had normal echocardiographic right ventricular function, and nine other patients had a...

journal_title：Critical care medicine

authors： Jardin F,Gueret P,Dubourg O,Farcot JC,Margairaz A,Bourdarias JP

更新日期：1985-11-01 00:00:00

abstract：:Changes in pulmonary function and the development of atelectasis in the postoperative period have been well documented in the adult population. The use of incentive spirometry has been shown to be effective in the prevention of these postoperative complications. At the Hospital of Sick Children, we studied 17 children...

journal_title：Critical care medicine

authors： Krastins I,Corey ML,McLeod A,Edmonds J,Levison H,Moes F

更新日期：1982-08-01 00:00:00

abstract：OBJECTIVES:To review mechanisms underlying sepsis-induced cardiac dysfunction in general and intrinsic myocardial depression in particular. DATA SOURCE:MEDLINE database. DATA SYNTHESIS:Myocardial depression is a well-recognized manifestation of organ dysfunction in sepsis. Due to the lack of a generally accepted defi...

journal_title：Critical care medicine

authors： Rudiger A,Singer M

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVES:In postcardiac surgery patients, we often noticed that monitored tidal volumes exceeded the ventilator settings. We investigated whether cardiogenic oscillation causes overestimation of tidal volume. DESIGN:Prospective, observational, clinical study. SETTING:Surgical intensive care unit in a national heart...

journal_title：Critical care medicine

authors： Imanaka H,Takeuchi M,Tachibana K,Nishimura M

更新日期：2004-07-01 00:00:00

abstract：OBJECTIVE:Our knowledge of the molecular mechanisms of sepsis has attained exponential growth. Yet, the pillars of its care remain antibiotics, fluid resuscitation, and physiologic support of failing organ systems. The inability to bring biologic breakthroughs to the bedside is not for lack of effort. Over 60 clinical ...

journal_title：Critical care medicine

authors： Lewis AJ,Lee JS,Rosengart MR

更新日期：2018-09-01 00:00:00

abstract：:offstudied hemodynamic and renal effects of increasing the dosage of dopamine (DP) by 5 micrograms/kg X min, in 7 patients with peritonitis and clinical findings of septic shock, all of whom were already receiving variable dosages of DP. Stroke index (SI) (p less than .01), except in 3 cases, and mean arterial pressur...

journal_title：Critical care medicine

authors： de la Cal MA,Miravalles E,Pascual T,Esteban A,Ruiz-Santana S

更新日期：1984-01-01 00:00:00

abstract：OBJECTIVE:To test the reliability and validity of a modified moral distress tool, originally developed for the nursing profession, on respiratory care practitioners. To describe the relationship between moral distress, career dissatisfaction, and job turnover in respiratory care. DESIGN:A 28-question survey was develo...

journal_title：Critical care medicine

authors： Schwenzer KJ,Wang L

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:To investigate the interaction and involvement of hydrogen sulfide and transient receptor potential vanilloid type 1 in the pathogenesis of sepsis. Hydrogen sulfide has been demonstrated to be involved in many inflammatory states including sepsis. Its contribution in neurogenic inflammation has been suggested...

journal_title：Critical care medicine

authors： Ang SF,Moochhala SM,Bhatia M

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVES:Despite having dysregulated iron metabolism, critically ill patients may receive exogenous iron for the treatment of anemia. Iron is associated with increased tissue apoptosis and may facilitate bacterial growth. We hypothesized that exogenous iron administration given after the onset of sepsis would lead to...

journal_title：Critical care medicine

authors： Javadi P,Buchman TG,Stromberg PE,Husain KD,Dunne WM,Woolsey CA,Turnbull IR,Hotchkiss RS,Karl IE,Coopersmith CM

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVES:Acinetobacter baumannii complex bacteremia has been identified increasingly in critical patients admitted in ICUs. Notably, A. baumannii complex bacteremia has a high mortality rate, yet the risk factors associated with mortality remain unclear and controversial. DESIGN:Retrospective study. SETTING:All adu...

journal_title：Critical care medicine

authors： Lee HY,Chen CL,Wu SR,Huang CW,Chiu CH

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVES:To evaluate the association between length of ICU stay and 1-year mortality for elderly patients who survived to hospital discharge in the United States. DESIGN:Retrospective cohort study of a random sample of Medicare beneficiaries who survived to hospital discharge, with 1- and 3-year follow-up, stratifie...

journal_title：Critical care medicine

authors： Moitra VK,Guerra C,Linde-Zwirble WT,Wunsch H

更新日期：2016-04-01 00:00:00

abstract：:A new device has been developed to estimate continuously and noninvasively cardiac output from the thoracic electrical bioimpedance (CObi). CObi was compared to cardiac output by thermodilution (COtd) in five anesthetized dogs. Blood pressure, blood volume, and blood flow were manipulated by hemorrhage and infusions o...

journal_title：Critical care medicine

authors： Tremper KK,Hufstedler SM,Barker SJ,Zaccari J,Harris D,Anderson S,Roohk V

更新日期：1986-03-01 00:00:00

abstract：OBJECTIVE:To determine whether the difference between oxygen consumption (VO2) measured by metabolic gas monitoring systems and by the Fick principle is related to venous admixture, deadspace/tidal volume ratio, or alveolar-arterial oxygen tension gradient in critically ill patients. DESIGN:A prospective study. SETTI...

journal_title：Critical care medicine

authors： Myburgh JA,Webb RK,Worthley LI

更新日期：1992-04-01 00:00:00

abstract：OBJECTIVES:To assess the reversibility of acute kidney injury-induced neutrophil dysfunction and to identify involved mechanisms. DESIGN:Controlled laboratory experiment and prospective observational clinical study. SETTING:University laboratory and hospital. SUBJECTS:C57BL/6 wild-type mice. PATIENTS:Patients with ...

journal_title：Critical care medicine

authors： Singbartl K,Miller L,Ruiz-Velasco V,Kellum JA

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVES:Although the mortality of severe sepsis is easily quantified, the actual cause and timing of death from severe sepsis are less defined. We used the INDEPTH (International Integrated Database for the Evaluation of Severe Sepsis and Drotrecogin alfa activated) database to investigate the reported cause of deat...

journal_title：Critical care medicine

authors： Vincent JL,Nelson DR,Williams MD

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:Although the development of ventilator-associated pneumonia (VAP) is assumed to increase costs of intensive care unit stay, it is unknown whether prevention of VAP by means of oropharyngeal decontamination is cost-effective. Because of wide ranges of individual patient costs, crude cost comparisons did not sh...

journal_title：Critical care medicine

authors： van Nieuwenhoven CA,Buskens E,Bergmans DC,van Tiel FH,Ramsay G,Bonten MJ

更新日期：2004-01-01 00:00:00

abstract：RATIONALE:Despite recent advances in critical care and ventilator management, acute lung injury and acute respiratory distress syndrome continue to cause significant morbidity and mortality. Granulocyte-macrophage colony stimulating factor may be beneficial for patients with acute respiratory distress syndrome. OBJECT...

journal_title：Critical care medicine

authors： Paine R 3rd,Standiford TJ,Dechert RE,Moss M,Martin GS,Rosenberg AL,Thannickal VJ,Burnham EL,Brown MB,Hyzy RC

更新日期：2012-01-01 00:00:00

abstract：:Cardiac arrest has a poor prognosis, regardless of age group. Children who fail to respond to two standard doses of epinephrine (0.01 mg/kg) rarely survive to hospital discharge, and most die without the return of spontaneous circulation (ROSC). We treated seven consecutive children in cardiac arrest with high dose ep...

journal_title：Critical care medicine

authors： Goetting MG,Paradis NA

更新日期：1989-12-01 00:00:00