Continuous noninvasive estimation of cardiac output by electrical bioimpedance: an experimental study in dogs.

Abstract:

:A new device has been developed to estimate continuously and noninvasively cardiac output from the thoracic electrical bioimpedance (CObi). CObi was compared to cardiac output by thermodilution (COtd) in five anesthetized dogs. Blood pressure, blood volume, and blood flow were manipulated by hemorrhage and infusions of sodium nitroprusside and phenylephrine. These data were used to determine the correlation between CObi and COtd under conditions of hypotensive normal flow and normotensive low flow, as well as during hemorrhagic shock and resuscitation. The CObi device was calibrated in vivo to COtd for each dog at the beginning of each experiment. CObi had a significant positive correlation with COtd throughout the experiments (r = 0.84, slope = 0.91, intercept = 0.55, p less than 0.01), and CObi predicted COtd with a standard error of the estimate of 0.81 L/min. Neither heart rate nor mean arterial pressure was significantly correlated with COtd or CObi. During severe hemorrhagic shock, CObi could not determine cardiac output in two of the dogs when COtd averaged 1.7 L/min. These data indicate that CObi is a blood-flow related variable that can be monitored continuously.

journal_name

Crit Care Med

journal_title

Critical care medicine

authors

Tremper KK,Hufstedler SM,Barker SJ,Zaccari J,Harris D,Anderson S,Roohk V

doi

10.1097/00003246-198603000-00013

subject

Has Abstract

pub_date

1986-03-01 00:00:00

pages

231-3

issue

3

eissn

0090-3493

issn

1530-0293

journal_volume

14

pub_type

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