Cerebral blood flow and oxygen consumption in acute brain injury with acute anemia: an alternative for the cerebral metabolic rate of oxygen consumption?

abstract：OBJECTIVE:To examine the effect of hypertonic saline on bacterial translocation and the number and function of natural killer and T cells in controlled hemorrhagic shock. DESIGN:Randomized controlled study. Duration of follow-up was 24 hrs. SETTING:University research laboratory. SUBJECTS:Adult male Sprague-Dawley r...

journal_title：Critical care medicine

authors： Hirsh M,Dyugovskaya L,Bashenko Y,Krausz MM

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVE:To investigate a role of the opiate system during acute hypoxic hypoxia, the effects of naloxone and morphine on hypoxic survival rate were investigated in awake adult mice. DESIGN:Prospective, randomized, animal trial. SETTING:University research laboratory. SUBJECTS:Male dd-Y mice (n = 864 in experiment ...

journal_title：Critical care medicine

authors： Endoh H,Taga K,Yamakura T,Sato K,Watanabe I,Fukuda S,Shimoji K

更新日期：1999-09-01 00:00:00

abstract：OBJECTIVE:To determine whether the supplementation of parenteral nutrition with ω-3 fatty acids confers treatment benefits to critically ill adult patients. DATA SOURCE:We performed computerized searches for relevant articles from 1996 to June 2011 on MEDLINE, EMBASE, and the Cochrane register of controlled trials and...

journal_title：Critical care medicine

authors： Palmer AJ,Ho CK,Ajibola O,Avenell A

更新日期：2013-01-01 00:00:00

abstract：:Total parenteral nutrition (TPN) increases CO2 production (VCO2) in patients on intermittent positive-pressure ventilation who cannot match their CO2 excretion to the CO2 load, leading to an increase in PaCO2. We studied gas exchange and blood gas values in six patients with chronic respiratory failure, who were venti...

journal_title：Critical care medicine

authors： Herve P,Simonneau G,Girard P,Cerrina J,Mathieu M,Duroux P

更新日期：1985-07-01 00:00:00

abstract：OBJECTIVE:Effective therapies are needed to reverse the increased vascular permeability that characterizes acute inflammatory diseases such as acute lung injury. FTY720 is a pharmaceutical analog of the potent barrier-enhancing phospholipid, sphingosine 1-phosphate. Because both FTY720 and sphingosine 1-phosphate have ...

journal_title：Critical care medicine

authors： Wang L,Sammani S,Moreno-Vinasco L,Letsiou E,Wang T,Camp SM,Bittman R,Garcia JG,Dudek SM

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVES:In postcardiac surgery patients, we often noticed that monitored tidal volumes exceeded the ventilator settings. We investigated whether cardiogenic oscillation causes overestimation of tidal volume. DESIGN:Prospective, observational, clinical study. SETTING:Surgical intensive care unit in a national heart...

journal_title：Critical care medicine

authors： Imanaka H,Takeuchi M,Tachibana K,Nishimura M

更新日期：2004-07-01 00:00:00

abstract：:The effects of PEEP and subsequent augmentation of cardiac output by sodium nitroprusside (SNP) were examined in a canine model of asymmetric oleic acid injury to the right lung. PEEP (9.2 +/- 0.5 cm H2O) was added to six animals to decrease venous admixture (Qsp/Qt) from 50.6 +/- 4.4% to 16.0 +/- 1.3% (p less than .0...

journal_title：Critical care medicine

authors： Johnston WE,Vinten-Johansen J,Tommasi E

更新日期：1989-03-01 00:00:00

abstract：:The authors have examined cardiopulmonary resuscitation (CPR) skills retention in a police force initially trained to instructor level performance skills as defined by the 1977 American Heart Association Instructor Manual. In 1977, the entire Winnipeg Police Force received a basic 8-h course of CPR training with recor...

journal_title：Critical care medicine

authors： Tweed WA,Wilson E,Isfeld B

更新日期：1980-11-01 00:00:00

abstract：OBJECTIVE:High-frequency oscillation has been proposed for use in adult acute respiratory distress syndrome. However, limited data are available on the effect of pressure amplitude and rate (Hz) on tidal volumes delivered during high-frequency oscillation in adults. DESIGN:Prospective, animal model, lung injury study....

journal_title：Critical care medicine

authors： Sedeek KA,Takeuchi M,Suchodolski K,Kacmarek RM

更新日期：2003-01-01 00:00:00

abstract：:The ICU has been considered a psychologically stressful environment. Although numerous studies have investigated this stress in ICU nurses, virtually none have examined how stressful the ICU is for physicians. This prospective study compares housestaff physicians' ratings of stress in the ICU to other medical-surgical...

journal_title：Critical care medicine

authors： Eisendrath SJ,Link N,Matthay M

更新日期：1986-02-01 00:00:00

abstract：OBJECTIVE:Vascular dysfunction plays a central role in sepsis, and it is characterized by hypotension and hyporesponsiveness to vasoconstrictors. Nitric oxide is regarded as a central element of sepsis vascular dysfunction. The high amounts of nitric oxide produced during sepsis are mainly derived from the inducible is...

journal_title：Critical care medicine

authors： Nardi GM,Scheschowitsch K,Ammar D,de Oliveira SK,Arruda TB,Assreuy J

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:To develop definitions of infection that can be used in clinical trials in patients with sepsis. CONTEXT:Infection is a key component of the definition of sepsis, yet there is currently no agreement on the definitions that should be used to identify specific infections in patients with sepsis. Agreeing on a ...

journal_title：Critical care medicine

authors： Calandra T,Cohen J,International Sepsis Forum Definition of Infection in the ICU Consensus Conference.

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVE:To determine the effect of a bolus infusion of diaspirin cross-linked hemoglobin (DCLHb or hemoglobin crosfumaril) on the ileal mucosal microcirculation in septic rats. DESIGN:Prospective, randomized, single-blinded study. SETTING:University-affiliated animal research laboratory. SUBJECTS:Twenty-four male ...

journal_title：Critical care medicine

authors： Sielenkämper AW,Eichelbrönner O,Martin CM,Madorin SW,Chin-Yee IH,Sibbald WJ

更新日期：2000-03-01 00:00:00

abstract：:Ventricular fibrillation (VF) can masquerade as asystole. We report a 54-yr-old male in cardiac arrest who, on surface ECG, appeared to be in VF or asystole. A bedside intracardiac recording using a transmyocardial pacing wire showed the true rhythm to be atrial fibrillation (AF) with high grade atrioventricular block...

journal_title：Critical care medicine

authors： Ornato JP,Gonzales ER,Garnett R

更新日期：1987-04-01 00:00:00

abstract：:Cardiac arrest is most commonly encountered as the end result of severe derangements in metabolic homeostasis. These derangements may include toxic, ischemic, or electrophysiological causes of circulatory and/or respiratory arrests. Occasionally, mechanical obstruction or impediment to circulation may cause cardiac ar...

journal_title：Critical care medicine

authors： Ewer MS,Ali MK,Frazier OH

更新日期：1982-03-01 00:00:00

abstract：:Hemodynamic effects of controlled mechanical ventilation (CMV), intermittent mandatory ventilation (IMV), and intermittent mandatory ventilation with 5 cm H20 PEEP (IMV 5 peep) were studied in 20 patients after aortocoronary bypass surgery. Significant increases in cardiac index (CI) and stroke volume index (SI) (p le...

journal_title：Critical care medicine

authors： Mathru M,Rao TL,El-Etr AA,Pifarre R

更新日期：1982-07-01 00:00:00

abstract：OBJECTIVES:Vascular beds vary in their responses to atrial natriuretic peptide and sodium nitroprusside. Both of these agents dilate blood vessels by increasing intracellular guanosine 3',5'-cyclic monophosphate (cyclic-GMP) but activate different enzymes in the vascular smooth muscle cell. We aimed to determine if the...

journal_title：Critical care medicine

authors： Zhang LM,Castresana M,Newman WH

更新日期：1994-09-01 00:00:00

abstract：OBJECTIVE:To describe a case of intentional ingestion of hand sanitizer in our hospital and to review published cases and those reported to the American Association of Poison Control Centers' National Poison Data System. DESIGN:A case report, a literature review of published cases, and a query of the National Poison D...

journal_title：Critical care medicine

authors： Gormley NJ,Bronstein AC,Rasimas JJ,Pao M,Wratney AT,Sun J,Austin HA,Suffredini AF

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVES:To describe long-term survival in patients with severe acute respiratory distress syndrome and assess differences in patient characteristics and outcomes among those who receive rescue therapies (prone position ventilation, inhaled nitric oxide, or inhaled epoprostenol) versus conventional treatment. DESIGN...

journal_title：Critical care medicine

authors： Khandelwal N,Hough CL,Bansal A,Veenstra DL,Treggiari MM

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVE:Recent studies have demonstrated the therapeutic effectiveness and pharmacologic mechanisms of hyperbaric oxygen therapy (HBOT) in the treatment of a systemic shock state. To elucidate the in vivo role of HBOT during sepsis, we evaluated the effects of HBOT on intestinal mucosal injury and bacterial transloca...

journal_title：Critical care medicine

authors： Sakoda M,Ueno S,Kihara K,Arikawa K,Dogomori H,Nuruki K,Takao S,Aikou T

更新日期：2004-08-01 00:00:00

abstract：:A high rate of death from septic shock persists despite general improvements in care. The relative failure of mechanistically based therapies in various clinical trials should also trigger a reconsideration of such mechanistic approaches. Despite reversion of shock by hydrocortisone, the similar death rate compared wi...

journal_title：Critical care medicine

authors： Lukaszewicz AC,Payen D

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND AND METHODS:Calcium-channel blockers may attenuate vasospasm after transient ischemia and improve organ blood flow after resuscitation. Our aim was to assess the effect of diltiazem on systemic oxygen delivery and consumption, hemodynamics, electroencephalogram (EEG), and organ blood flow after restoration o...

journal_title：Critical care medicine

authors： Lindner KH,Prengel AW,Ahnefeld FW,Ensinger H,Schürmann W

更新日期：1992-05-01 00:00:00

abstract：OBJECTIVE:We investigated whether serum levels of neuron-specific enolase (NSE) and S-100beta protein could be used to evaluate cerebral injury and to predict outcome in severe sepsis and severe septic shock. DESIGN:Prospective study. SETTING:University hospital. PATIENTS AND MEASUREMENTS:In 170 consecutively enroll...

journal_title：Critical care medicine

authors： Nguyen DN,Spapen H,Su F,Schiettecatte J,Shi L,Hachimi-Idrissi S,Huyghens L

更新日期：2006-07-01 00:00:00

abstract：:Trauma is the leading cause of both morbidity and mortality in the pediatric population, and traumatic injury causes > 50% of all childhood deaths. Significant mortality rates have been reported for children with traumatic brain injury. Although children have better survival rates as compared with adults with traumati...

journal_title：Critical care medicine

authors： Mazzola CA,Adelson PD

更新日期：2002-11-01 00:00:00

abstract：:Accurate assessment and rapid decision-making are essential to save lives and improve performance in critical care medicine. Real-time point-of-care ultrasound has become an invaluable adjunct to the clinical evaluation of critically ill and injured patients both for pre- and in-hospital situations. However, a high le...

journal_title：Critical care medicine

authors： Neri L,Storti E,Lichtenstein D

更新日期：2007-05-01 00:00:00

abstract：:The need for closed-loop control of blood pressure in acute hypertension after cardiac surgery was evaluated by estimating the amount of nurse-time required to adjust the infusion rate of sodium nitroprusside. The evaluation consisted of a nationwide telephone survey of head nurses in postsurgical ICUs at 9 institutio...

journal_title：Critical care medicine

authors： Mitchell RR

更新日期：1982-12-01 00:00:00

abstract：OBJECTIVE:We studied the in-hospital course, long-term prognosis, and functional status of elderly patients with life-threatening cardiogenic pulmonary edema requiring mechanical ventilation. DESIGN:Semiprospective evaluation. SETTING:Twelve intensive care units and one emergency prehospital medical department in uni...

journal_title：Critical care medicine

authors： Adnet F,Le Toumelin P,Leberre A,Minadeo J,Lapostolle F,Plaisance P,Cupa M

更新日期：2001-04-01 00:00:00

abstract：OBJECTIVES:To determine: a) any heart site or tissue-specific differences in the response to increased perfusion potassium concentrations, and b) the cellular site (intracellular vs. extracellular) of the effect of calcium on reversing electrocardiographic effects of hyperkalemia. DESIGN:In vitro prospective, repeated...

journal_title：Critical care medicine

authors： Bisogno JL,Langley A,Von Dreele MM

更新日期：1994-04-01 00:00:00

abstract：OBJECTIVES:The absence of N20 somatosensory evoked potential after cardiac arrest is related to poor outcome. However, discrimination between the low-amplitude and the absence of N20 is challenging. P25 and P30 are short-latency positive peaks with latencies between 25 and 30 ms following N20 (P25/30). P25/30 is eviden...

journal_title：Critical care medicine

authors： Kim SW,Oh JS,Park J,Jeong HH,Kim JH,Wee JH,Oh SH,Choi SP,Park KN,Cerebral Resuscitation and Outcome evaluation Within catholic Network (CROWN) Investigators.

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:The 2003 global outbreak of severe acute respiratory syndrome (SARS) provided numerous challenges to the delivery of critical care. The Toronto critical care community has learned important lessons from SARS, which will help in preparation for future disease outbreaks. OBJECTIVES:The objectives of this stud...

journal_title：Critical care medicine

authors： Booth CM,Stewart TE

更新日期：2005-01-01 00:00:00