Transforming growth factor-beta: a mediator of cell regulation in acute respiratory distress syndrome.

abstract：OBJECTIVES:Sepsis-associated changes of the arachidonic acid metabolism and the utility of arachidonic acid metabolites for the diagnosis of sepsis have been poorly investigated so far. Therefore, the primary objective of our study was to screen for differentially regulated arachidonic acid metabolites in septic patien...

journal_title：Critical care medicine

authors： Bruegel M,Ludwig U,Kleinhempel A,Petros S,Kortz L,Ceglarek U,Holdt LM,Thiery J,Fiedler GM

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVE:The acute respiratory distress syndrome may complicate postpartum hemorrhagic shock and resuscitation, but its mechanisms are not yet well defined. We studied the lung inflammatory response to postpartum hemorrhagic shock and resuscitation in a rabbit model and the role of the nuclear factor-κB pathway. DESI...

journal_title：Critical care medicine

authors： Sheng C,Yu YH,Zhao KS,Huang LP,Lodato RF,Wang ZJ,Wang CH,Wang SH,Zha DS

更新日期：2012-05-01 00:00:00

abstract：:The disadvantages of external ventricular drainage are the threat of sepsis and the nuisance of dislodging a precarious system in routine care. The experience of the authors with nearly 200 cases using a long ventricular catheter demonstrates that a subgaleal tunnel can be easily made for the ventricular catheter usin...

journal_title：Critical care medicine

authors： Saunders RL,Lyons TA

更新日期：1979-12-01 00:00:00

abstract：:We report a case of an amniotic fluid embolism (AFE) causing a cardiorespiratory arrest associated temporally with ingestion of castor oil in a full-term normal pregnancy. Risk factors usually associated with AFE were not found in this patient. ...

journal_title：Critical care medicine

authors： Steingrub JS,Lopez T,Teres D,Steingart R

更新日期：1988-06-01 00:00:00

abstract：OBJECTIVE:Recent in vivo studies of both septic humans and animals demonstrate that leukocyte delivery is attenuated to sites remote from the primary infection. The mechanisms for this are not entirely clear. L-selectin is integral to rolling, the first step in leukocyte recruitment to an inflammatory site. L-selectin ...

journal_title：Critical care medicine

authors： Ferri LE,Swartz D,Christou NV

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:To review the physiology of the regulation and determinants of heart rate and the significance in the management of critically ill patients. DATA SOURCES:The MEDLINE database, references from selected articles, and the author's personal database. DATA SYNTHESIS:This review begins with the regulation of card...

journal_title：Critical care medicine

authors： Magder SA

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to evaluate the relative frequency of pediatric in-hospital cardiopulmonary resuscitation events occurring in ICUs compared to general wards. We hypothesized that the proportion of pediatric cardiopulmonary resuscitation provided in ICUs versus general wards has increased over the p...

journal_title：Critical care medicine

authors： Berg RA,Sutton RM,Holubkov R,Nicholson CE,Dean JM,Harrison R,Heidemann S,Meert K,Newth C,Moler F,Pollack M,Dalton H,Doctor A,Wessel D,Berger J,Shanley T,Carcillo J,Nadkarni VM,Eunice Kennedy Shriver National Institute

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVES:Carbon monoxide poisoning affects 50,000 per year in the United States alone. Mortality is approximately 3%, and up to 40% of survivors suffer from permanent neurocognitive and affective deficits. Hyperbaric oxygen therapy has shown benefit on reducing the long-term neurologic sequelae of carbon monoxide poi...

journal_title：Critical care medicine

authors： Rose JJ,Nouraie M,Gauthier MC,Pizon AF,Saul MI,Donahoe MP,Gladwin MT

更新日期：2018-07-01 00:00:00

abstract：OBJECTIVE:To evaluate a new technique for pressure-volume curve tracing. DESIGN:Prospective experimental study. SETTING:Animal research laboratory. SUBJECTS:Six anesthetized rats. INTERVENTIONS:Two pressure-volume curves were obtained by means of the super-syringe method (gold standard) and the continuous positive ...

journal_title：Critical care medicine

authors： Albaiceta GM,Piacentini E,Villagrá A,Lopez-Aguilar J,Taboada F,Blanch L

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:We investigated whether serum levels of neuron-specific enolase (NSE) and S-100beta protein could be used to evaluate cerebral injury and to predict outcome in severe sepsis and severe septic shock. DESIGN:Prospective study. SETTING:University hospital. PATIENTS AND MEASUREMENTS:In 170 consecutively enroll...

journal_title：Critical care medicine

authors： Nguyen DN,Spapen H,Su F,Schiettecatte J,Shi L,Hachimi-Idrissi S,Huyghens L

更新日期：2006-07-01 00:00:00

abstract：OBJECTIVES:To determine if vecuronium doses individualized by peripheral nerve stimulation are lower than those doses chosen by standard clinical techniques; and to determine whether patients monitored by peripheral nerve stimulation exhibit shorter recovery times and less prolonged neuromuscular blockade after discont...

journal_title：Critical care medicine

authors： Rudis MI,Sikora CA,Angus E,Peterson E,Popovich J Jr,Hyzy R,Zarowitz BJ

更新日期：1997-04-01 00:00:00

abstract：OBJECTIVE:Monitoring of ventilation performance during cardiopulmonary resuscitation would be desirable to improve the quality of cardiopulmonary resuscitation. To investigate the potential for measuring ventilation rate and inspiration time, we calculated the correlation in waveform between transthoracic impedance mea...

journal_title：Critical care medicine

authors： Losert H,Risdal M,Sterz F,Nysaether J,Köhler K,Eftestøl T,Wandaller C,Myklebust H,Uray T,Sodeck G,Laggner AN

更新日期：2006-09-01 00:00:00

abstract：:Pentoxifylline has been shown to increase red blood cell malleability, thus increasing capillary blood flow in a number of disease states. The present study was undertaken to determine whether pentoxifylline might improve tissue oxygenation after anesthesia and during an operation in rats. Rats were anesthetized and d...

journal_title：Critical care medicine

authors： Soliman MH,O'Neal K,Waxman K

更新日期：1987-02-01 00:00:00

abstract：OBJECTIVES:Studies have shown that endothelium-dependent relaxation (mediated by endothelium-derived nitric oxide) is depressed during the early, hyperdynamic stage of sepsis. Although it is known that ATP-MgCl2 produces beneficial effects following various adverse circulatory conditions, it remains unknown whether thi...

journal_title：Critical care medicine

authors： Wang P,Ba ZF,Cioffi WG,Bland KI,Chaudry IH

更新日期：1999-05-01 00:00:00

abstract：:Gastric mucosal damage occurs in critically ill patients in intensive care units and develops in the setting of severe physiologic stress. Within 24 hrs of admission to the intensive care unit, 75% to 100% of critically ill patients demonstrate evidence of stress-related mucosal disease. Stress ulcers present a risk o...

journal_title：Critical care medicine

authors： Fennerty MB

更新日期：2002-06-01 00:00:00

abstract：:Total parenteral nutrition (TPN) increases CO2 production (VCO2) in patients on intermittent positive-pressure ventilation who cannot match their CO2 excretion to the CO2 load, leading to an increase in PaCO2. We studied gas exchange and blood gas values in six patients with chronic respiratory failure, who were venti...

journal_title：Critical care medicine

authors： Herve P,Simonneau G,Girard P,Cerrina J,Mathieu M,Duroux P

更新日期：1985-07-01 00:00:00

abstract：OBJECTIVE:Acute lung injury is a detrimental complication for victims of burn accidents. Airway obstruction plays an important role in pulmonary dysfunction in these patients. In this study, we tested the hypothesis that aerosolized anticoagulants will reduce the degree of airway obstruction and improve pulmonary funct...

journal_title：Critical care medicine

authors： Enkhbaatar P,Cox RA,Traber LD,Westphal M,Aimalohi E,Morita N,Prough DS,Herndon DN,Traber DL

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVE:The high incidence of lower lobe collapse in adult intensive care patients is well described. We aimed to document the incidence and distribution of acute lobar collapse in the pediatric intensive care setting. The influence of anatomical and pathophysiological differences between the adult and pediatric resp...

journal_title：Critical care medicine

authors： Thomas K,Habibi P,Britto J,Owens CM

更新日期：1999-08-01 00:00:00

abstract：OBJECTIVE:To describe a case of hepatic subcapsular hematoma causing an acute Budd-Chiari-like syndrome, leading to hepatic compartment syndrome, which combines compression of intrahepatic vessels on CT, acute liver failure, and refractory shock. DESIGN:Case report. SETTING:Surgical ICU of a university teaching hospi...

journal_title：Critical care medicine

authors： Marcaire F,Malavieille F,Pichot-Delahaye V,Floccard B,Rimmelé T

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVES:To examine a hygroscopic condenser after clinical use and to describe the interaction of a hygroscopic condenser and a closed circuit suction system used simultaneously. DESIGN:Prospective evaluation of hygroscopic condensers used clinically, and laboratory investigation of a hygroscopic condenser used with...

journal_title：Critical care medicine

authors： Martinez FJ,Pietchel S,Wise C,Walek J,Beamis JF

更新日期：1994-10-01 00:00:00

abstract：:Oral amiodarone's slow absorption handicaps rapid treatment of life-threatening arrhythmias. We used iv amiodarone to treat ten patients with hemodynamically significant atrial arrhythmias and life-threatening ventricular arrhythmias refractory to all conventional medical treatment. Arrhythmias were controlled in nine...

journal_title：Critical care medicine

authors： Alves LE,Rose EP,Cahill TB Jr

更新日期：1985-09-01 00:00:00

abstract：OBJECTIVE:The physicochemical approach, described by Stewart to investigate the acid-base balance, includes the strong ion gap (SIG), a quantitative measure of "unmeasured" anions, which strongly correlates to the corrected anion gap. The chemical nature of these anions is for the most part unknown. We hypothesized tha...

journal_title：Critical care medicine

authors： Moviat M,Terpstra AM,Ruitenbeek W,Kluijtmans LA,Pickkers P,van der Hoeven JG

更新日期：2008-03-01 00:00:00

abstract：:To achieve normocarbia during conventional mechanical ventilation, ventilator settings are determined initially on the basis of body weight. The best ventilator settings for CO2 elimination during high-frequency jet ventilation (HFJV) have not been so clearly defined. A recent study has suggested that eucarbia will be...

journal_title：Critical care medicine

authors： Bayly R,Sladen A,Tyler IL,Echegaray RF,Klain M,Guntupalli K

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the potential clinical, metabolic, and economic advantages of enteral nutrition over total parenteral nutrition. DESIGN:Prospective, randomized clinical trial. SETTING:Department of surgery in a university hospital. PATIENTS:Two hundred and fifty-seven patients with cancer of the stomach (n = 1...

journal_title：Critical care medicine

authors： Braga M,Gianotti L,Gentilini O,Parisi V,Salis C,Di Carlo V

更新日期：2001-02-01 00:00:00

abstract：OBJECTIVES:Although studies have indicated that adrenal insufficiency occurs after severe trauma and hemorrhagic shock, it remains controversial whether adrenal function is depressed during the late stage of polymicrobial sepsis. DESIGN:Prospective, controlled animal study. SETTING:A university research laboratory. ...

journal_title：Critical care medicine

authors： Koo DJ,Jackman D,Chaudry IH,Wang P

更新日期：2001-03-01 00:00:00

abstract：OBJECTIVE:Mechanical circulatory support can maintain vital organ perfusion in patients with cardiac failure unresponsive to standard pharmacologic treatment. The purpose of the current study was to report complication and survival rates in patients supported with emergency percutaneous venoarterial cardiopulmonary byp...

journal_title：Critical care medicine

authors： Schwarz B,Mair P,Margreiter J,Pomaroli A,Hoermann C,Bonatti J,Lindner KH

更新日期：2003-03-01 00:00:00

abstract：INTRODUCTION:Ventilator settings for patients with severe acute respiratory distress syndrome supported by venovenous extracorporeal membrane oxygenation are currently set arbitrarily. The impact on serum and pulmonary biotrauma markers of the transition to ultra-protective ventilation settings following extracorporeal...

journal_title：Critical care medicine

authors： Rozencwajg S,Guihot A,Franchineau G,Lescroat M,Bréchot N,Hékimian G,Lebreton G,Autran B,Luyt CE,Combes A,Schmidt M

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVE:To simultaneously determine perceived vs. practiced adherence to recommended interventions for the treatment of severe sepsis or septic shock. DESIGN:One-day cross-sectional survey. SETTING:Representative sample of German intensive care units stratified by hospital size. PATIENTS:Adult patients with severe...

journal_title：Critical care medicine

authors： Brunkhorst FM,Engel C,Ragaller M,Welte T,Rossaint R,Gerlach H,Mayer K,John S,Stuber F,Weiler N,Oppert M,Moerer O,Bogatsch H,Reinhart K,Loeffler M,Hartog C,German Sepsis Competence Network (SepNet).

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:To compare the results of cardiac output measurements obtained by lithium dilution and thermodilution. DESIGN:Case series, observational study. SETTING:High-dependency postoperative unit and intensive care unit of a teaching hospital. PATIENTS:Forty patients were studied. Thirty-four patients had undergoin...

journal_title：Critical care medicine

authors： Linton R,Band D,O'Brien T,Jonas M,Leach R

更新日期：1997-11-01 00:00:00

abstract：OBJECTIVE:To define the occurrence rate of acute respiratory distress syndrome (ARDS) using established criteria in a well-defined general patient population, to study the clinical course of ARDS when patients were ventilated using a "lung-protective" strategy, and to define the total costs of care. DESIGN:A 3-yr (199...

journal_title：Critical care medicine

authors： Valta P,Uusaro A,Nunes S,Ruokonen E,Takala J

更新日期：1999-11-01 00:00:00