The ups and downs of heart rate.

abstract：OBJECTIVE:To study the pulmonary effects of aspirating a mixture of sucralfate in water and sucralfate in hydrochloric acid in an animal model of aspiration pneumonia. DESIGN:Prospective, randomized, controlled study with repeated measures. SETTING:University research laboratory. SUBJECTS:Thirty-two in situ, isolate...

journal_title：Critical care medicine

authors： Toung TJ,Rosenfeld BA,Yoshiki A,Grayson RF,Traystman RJ

更新日期：1993-09-01 00:00:00

abstract：:Factors responsible for determining the position of the oxyhemoglobin equilibrium curve during the neonatal period are briefly reviewed and the clinical implications of these changes are examined. Two clinical trials employing exchange transfusions as an adjunct to conventional therapy of the severe respiratory distre...

journal_title：Critical care medicine

authors： Oski FA

更新日期：1979-09-01 00:00:00

abstract：OBJECTIVE:To investigate whether inhibition of cyclooxygenase-2, a critical component of the inflammatory pathway, is neuroprotective in a neonatal rat model of cerebral hypoxia-ischemia. The development of brain inflammation largely contributes to neonatal brain injury that may lead to a lifetime of neurologic deficit...

journal_title：Critical care medicine

authors： Fathali N,Ostrowski RP,Lekic T,Jadhav V,Tong W,Tang J,Zhang JH

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVES:To evaluate the use of multifrequency bioelectrical impedance analysis to predict creatinine/urea clearance based on 24 hours urine collection. A practical formula was developed, and its performance was compared with that of established formulas such as Cockcroft-Gault, Modification of Diet in Renal Disease,...

journal_title：Critical care medicine

authors： de Jong LAA,Otten-Helmers AG,Spronk PE,van Kan HJM

更新日期：2019-12-01 00:00:00

abstract：OBJECTIVE:To investigate the association of collaboration between intensive care unit (ICU) physicians and nurses and patient outcome. DESIGN:Prospective, descriptive, correlational study using self-report instruments. SETTINGS:A community teaching hospital medical ICU, a university teaching hospital surgical ICU, an...

journal_title：Critical care medicine

authors： Baggs JG,Schmitt MH,Mushlin AI,Mitchell PH,Eldredge DH,Oakes D,Hutson AD

更新日期：1999-09-01 00:00:00

abstract：:The objectives of this article were to review the causes and extent of hospital-associated infectious diarrhea and associated risks in the general hospital ward and intensive care unit (ICU), to compare microorganisms with similar symptoms to aid in recognition that will lead to timely and appropriate treatment and co...

journal_title：Critical care medicine

authors： Bobo LD,Dubberke ER

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVES:To investigate attitudes and practices regarding oxygen therapy in intensive care units (ICUs) and to devise quantitative descriptive indices. SETTING:Canadian university-affiliated adult ICUs. PARTICIPANTS:Fifty-two medical directors of ICUs in 48 institutions. INTERVENTION:Structured postal questionnair...

journal_title：Critical care medicine

authors： Mao C,Wong DT,Slutsky AS,Kavanagh BP

更新日期：1999-12-01 00:00:00

abstract：:Because determining cardiac output is difficult in premature infants, little is known about the hemodynamic effects of PEEP in this age group. We used pulsed-wave Doppler echocardiography to assess the hemodynamic effects of PEEP increments in ten premature infants with respiratory distress syndrome. At a PEEP of 4 cm...

journal_title：Critical care medicine

authors： Hausdorf G,Hellwege HH

更新日期：1987-07-01 00:00:00

abstract：BACKGROUND:Glycemic control is increasingly being recognized as a priority in the treatment of critically ill patients. Titration and monitoring of insulin infusions involve frequent blood glucose measurement to achieve target glucose ranges and prevent adverse events related to hypoglycemia. Therefore, it is imperativ...

journal_title：Critical care medicine

authors： Kanji S,Buffie J,Hutton B,Bunting PS,Singh A,McDonald K,Fergusson D,McIntyre LA,Hebert PC

更新日期：2005-12-01 00:00:00

abstract：OBJECTIVE:To define the occurrence rate of acute respiratory distress syndrome (ARDS) using established criteria in a well-defined general patient population, to study the clinical course of ARDS when patients were ventilated using a "lung-protective" strategy, and to define the total costs of care. DESIGN:A 3-yr (199...

journal_title：Critical care medicine

authors： Valta P,Uusaro A,Nunes S,Ruokonen E,Takala J

更新日期：1999-11-01 00:00:00

abstract：:The applicability of continuous arteriovenous hemofiltration (CAVH) for renal replacement therapy was evaluated in three infants and two young children with catastrophic medical and surgical illnesses. In the first four patients, CAVH was used in conjunction with either peritoneal or hemodialysis. In the fifth patient...

journal_title：Critical care medicine

authors： Leone MR,Jenkins RD,Golper TA,Alexander SR

更新日期：1986-12-01 00:00:00

abstract：OBJECTIVE:To determine whether the energy expenditure of mechanically ventilated multiple trauma patients correlates with the severity of injury and illness indices before important systemic infection has complicated the clinical course, and to compare the energy expenditure with the energy expenditure expected from th...

journal_title：Critical care medicine

authors： Brandi LS,Santini L,Bertolini R,Malacarne P,Casagli S,Baraglia AM

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVE:Acute renal failure can be treated with continuous renal replacement therapy (CRRT) or intermittent hemodialysis. There is no difference in mortality, although patients treated with CRRT may have a higher rate of renal recovery. Given these considerations, an estimate of the costs by modality may help in choo...

journal_title：Critical care medicine

authors： Manns B,Doig CJ,Lee H,Dean S,Tonelli M,Johnson D,Donaldson C

更新日期：2003-02-01 00:00:00

abstract：OBJECTIVE:To compare four different methods of endotracheal lidocaine administration with respect to the site of administration. DESIGN:Randomized controlled trial. SETTING:University hospital. PATIENTS:Thirty-two female patients (43.6 +/- 11.5 years old) undergoing elective gynecologic operations with an anesthesio...

journal_title：Critical care medicine

authors： Prengel AW,Lindner KH,Hähnel J,Ahnefeld FW

更新日期：1991-07-01 00:00:00

abstract：:Perfluorocarbon (PFC) emulsions are promising oxygen-carrying blood supplements for the treatment of shock and in organ preservation for transplantation. We used the isolated, blood-perfused, canine right lower lung lobe (RLL) to determine the effect of a PFC emulsion, Oxypherol (FC-43), upon lung fluid balance and he...

journal_title：Critical care medicine

authors： Hall JE,Ehrhart IC,Hofman WF

更新日期：1985-12-01 00:00:00

abstract：OBJECTIVES:To determine the incidence of enteral feed intolerance, identify factors associated with enteral feed intolerance, and assess the relationship between enteral feed intolerance and key nutritional and clinical outcomes in critically ill patients. DESIGN:Analysis of International Nutrition Survey database col...

journal_title：Critical care medicine

authors： Heyland DK,Ortiz A,Stoppe C,Patel JJ,Yeh DD,Dukes G,Chen YJ,Almansa C,Day AG

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVE:Critically ill patients often develop large gastric residual volumes during nasogastric feeding as a result of poor gastroduodenal motility. Nasojejunal feeding may decrease the severity of this complication. The aim of this study was to determine whether nasojejunal feeding improved tolerance of enteral nutr...

journal_title：Critical care medicine

authors： Davies AR,Froomes PR,French CJ,Bellomo R,Gutteridge GA,Nyulasi I,Walker R,Sewell RB

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVE:Pulmonary air embolism, causing vessel obstruction and primary or secondary reactions of blood, can lead to acute lung injury. In addition, nitric oxide has been known to play a key role in various causes of lung injury. In this study we employed the isolated rat lung model to investigate the effects of l-arg...

journal_title：Critical care medicine

authors： Chu SJ,Lee TY,Yan HC,Lin SH,Li MH

更新日期：2005-09-01 00:00:00

abstract：:We report a case of an amniotic fluid embolism (AFE) causing a cardiorespiratory arrest associated temporally with ingestion of castor oil in a full-term normal pregnancy. Risk factors usually associated with AFE were not found in this patient. ...

journal_title：Critical care medicine

authors： Steingrub JS,Lopez T,Teres D,Steingart R

更新日期：1988-06-01 00:00:00

abstract：:The ICU has been considered a psychologically stressful environment. Although numerous studies have investigated this stress in ICU nurses, virtually none have examined how stressful the ICU is for physicians. This prospective study compares housestaff physicians' ratings of stress in the ICU to other medical-surgical...

journal_title：Critical care medicine

authors： Eisendrath SJ,Link N,Matthay M

更新日期：1986-02-01 00:00:00

abstract：OBJECTIVE:Cytokines and adhesion molecules have a decisive role in the development of early inflammatory response as well as the late sequelae of sepsis. Because L-selectin-deficient mice are protected from lethal endotoxemia, blockade of L-selectin may provide a useful therapeutic option in human sepsis. Heparin has i...

journal_title：Critical care medicine

authors： Derhaschnig U,Pernerstorfer T,Knechtelsdorfer M,Hollenstein U,Panzer S,Jilma B

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND AND METHODS:Twelve adult male albino rabbits were assigned alternately to normotensive and hypotensive groups to assess the effect of hypovolemic shock on spontaneous correction of dilutional coagulopathy. All animals underwent dilutional exchange transfusion with 200 mL of rabbit RBCs and 5% human albumin. ...

journal_title：Critical care medicine

authors： Hewson JR,Prodger D,Roberts RS,Davis C,Fuller HD,Gregor P,Thomas EJ,Shragge BW,Russett J,Neame PB

更新日期：1991-02-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that hyperbaric oxygen therapy ameliorates delayed cognitive impairment after acute carbon monoxide poisoning by promoting neurogenesis through upregulating the brain-derived neurotrophic factor in the hippocampus. DESIGN:Laboratory animal experiments. SETTING:University/Medical cente...

journal_title：Critical care medicine

authors： Liu WC,Yang SN,Wu CW,Chen LW,Chan JY

更新日期：2016-01-01 00:00:00

abstract：:The hemodynamic response to a dopamine HCl infusion (10 microgram/kg per min) was measured in 25 adult patients with severe sepsis: there were 6 patients with circulatory hyperdynamic states, 9 patients with myocardial failure, and 10 with hypovolemia. Each patient also had acute respiratory failure. Changes of intrap...

journal_title：Critical care medicine

authors： Jardin F,Gurdjian F,Desfonds P,Margairaz A

更新日期：1979-06-01 00:00:00

abstract：OBJECTIVE:To study the effect of early and continuous venovenous hemofiltration (CVVH) on the plasma concentrations of several humoral mediators of inflammation and subsequent organ dysfunction in septic patients. DESIGN:Randomized, controlled trial. SETTING:Intensive care unit of a tertiary hospital. PATIENTS:Twent...

journal_title：Critical care medicine

authors： Cole L,Bellomo R,Hart G,Journois D,Davenport P,Tipping P,Ronco C

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:To compare the classification performance of the Revised Atlanta Classification, the Determinant-Based Classification, and a new modified Determinant-Based Classification according to observed mortality and morbidity. DESIGN:A prospective multicenter observational study conducted in 1-year period. SETTING:F...

journal_title：Critical care medicine

authors： Zubia-Olaskoaga F,Maraví-Poma E,Urreta-Barallobre I,Ramírez-Puerta MR,Mourelo-Fariña M,Marcos-Neira MP,Epidemiology of Acute Pancreatitis in Intensive Care Medicine Study Group.

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVES:Excessive inflammation is closely related to severity and outcome of sepsis. Because interleukin-1-receptor-associated kinase 1 is a key signaling protein in the activation of NF-κB during infection, we aimed to evaluate the effect of functionally relevant haplotypes of IRAK1 on severity, development of acut...

journal_title：Critical care medicine

authors： Toubiana J,Courtine E,Pène F,Viallon V,Asfar P,Daubin C,Rousseau C,Chenot C,Ouaaz F,Grimaldi D,Cariou A,Chiche JD,Mira JP

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVE:Significant mortality in patients with sepsis results from the development of multiple organ dysfunction syndrome. Small-volume resuscitation with 7.5% NaCl hypertonic saline has been proposed to restore physiologic hemodynamics in hemorrhagic shock. Therefore, we hypothesized that hypertonic saline resuscita...

journal_title：Critical care medicine

authors： Shih CC,Chen SJ,Chen A,Wu JY,Liaw WJ,Wu CC

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVE:To analyze plasma interferon-gamma and interleukin-10 concentrations in patients with systemic meningococcal disease and patients with severe Gram-positive septic shock caused by Streptococcus pneumoniae or Staphylococcus aureus. To study the in vitro cytokine (interferon-gamma and interleukin-10) responses i...

journal_title：Critical care medicine

authors： Bjerre A,Brusletto B,Høiby EA,Kierulf P,Brandtzaeg P

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVES:To evaluate the timing of foregoing life-sustaining treatments in patients enrolled in a sepsis trial and to determine their influence on patient outcome and trial results. DESIGN:Subset of patients in a prospective, randomized, double-blind, placebo-controlled study. SETTING:Twenty-three academic medical ...

journal_title：Critical care medicine

authors： Sprung CL,Eidelman LA,Pizov R,Fisher CJ Jr,Ziegler EJ,Sadoff JC,Straube RC,McCloskey RV

更新日期：1997-03-01 00:00:00