Assessment of the development of choked flow during total liquid ventilation.

abstract：OBJECTIVE:To review current knowledge about the impact of prolonged mechanical ventilation on diaphragmatic function and biology. MEASUREMENTS:Systematic literature review. CONCLUSIONS:Prolonged mechanical ventilation can promote diaphragmatic atrophy and contractile dysfunction. As few as 18 hrs of mechanical ventil...

journal_title：Critical care medicine

authors： Powers SK,Kavazis AN,Levine S

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:To assess the effectiveness of routine intensive care unit surveillance compared with frequent 12-lead electrocardiogram monitoring for detecting electrocardiogram evidence suggestive of prolonged myocardial ischemia in vascular surgery patients. DESIGN:Prospective cohort trial. SETTING:Intensive care unit....

journal_title：Critical care medicine

authors： Martinez EA,Kim LJ,Faraday N,Rosenfeld B,Bass EB,Perler BA,Williams GM,Dorman T,Pronovost PJ

更新日期：2003-09-01 00:00:00

abstract：OBJECTIVES:To determine whether aerosolized antibiotics can be delivered efficiently to the lower respiratory tract in mechanically ventilated patients and to define possible clinical responses to these agents. DESIGN:Prospective serial study with cases as their own control. SETTING:A 10-bed respiratory care unit for...

journal_title：Critical care medicine

authors： Palmer LB,Smaldone GC,Simon SR,O'Riordan TG,Cuccia A

更新日期：1998-01-01 00:00:00

abstract：RATIONALE:Despite recent advances in critical care and ventilator management, acute lung injury and acute respiratory distress syndrome continue to cause significant morbidity and mortality. Granulocyte-macrophage colony stimulating factor may be beneficial for patients with acute respiratory distress syndrome. OBJECT...

journal_title：Critical care medicine

authors： Paine R 3rd,Standiford TJ,Dechert RE,Moss M,Martin GS,Rosenberg AL,Thannickal VJ,Burnham EL,Brown MB,Hyzy RC

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVES:Our goal was to "reverse translate" the human response to surgical sepsis into the mouse by modifying a widely adopted murine intra-abdominal sepsis model to engender a phenotype that conforms to current sepsis definitions and follows the most recent expert recommendations for animal preclinical sepsis resea...

journal_title：Critical care medicine

authors： Stortz JA,Hollen MK,Nacionales DC,Horiguchi H,Ungaro R,Dirain ML,Wang Z,Wu Q,Wu KK,Kumar A,Foster TC,Stewart BD,Ross JA,Segal M,Bihorac A,Brakenridge S,Moore FA,Wohlgemuth SE,Leeuwenburgh C,Mohr AM,Moldawer LL,E

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVE:To investigate a role of the opiate system during acute hypoxic hypoxia, the effects of naloxone and morphine on hypoxic survival rate were investigated in awake adult mice. DESIGN:Prospective, randomized, animal trial. SETTING:University research laboratory. SUBJECTS:Male dd-Y mice (n = 864 in experiment ...

journal_title：Critical care medicine

authors： Endoh H,Taga K,Yamakura T,Sato K,Watanabe I,Fukuda S,Shimoji K

更新日期：1999-09-01 00:00:00

abstract：OBJECTIVE:To determine the financial impact of a sepsis protocol designed for use in the emergency department. DESIGN:Retrospective analysis of a before-after study testing the implications of sepsis protocol. SETTING:Academic, tertiary care hospital in the United States. PATIENTS:Persons with septic shock presentin...

journal_title：Critical care medicine

authors： Shorr AF,Micek ST,Jackson WL Jr,Kollef MH

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVES:There is substantial variation in use of life sustaining technologies in patients near the end of life but little is known about variation in physicians' initial ICU admission and intubation decision making processes. Our objective is to describe variation in hospital-based physicians' communication behavior...

journal_title：Critical care medicine

authors： Uy J,White DB,Mohan D,Arnold RM,Barnato AE

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND AND METHODS:We aimed to characterize the effects of an endotoxin insult (Escherichia coli 0127:B8) on the relationships between pulmonary vascular pressure and flow in intact dogs. To achieve this goal, multipoint plots of total pressure gradient, arterial pressure gradient, and venous pressure gradient vs. ...

journal_title：Critical care medicine

authors： D'Orio V,Fatemi M,Marnette JM,Mendes P,Saad G,Martinez C,Marcelle R

更新日期：1992-07-01 00:00:00

abstract：:Clinically, asystole or a bradyarrhythmia may follow countershock of ventricular fibrillation (VF) in up to 40% of attempts. This study evaluated the effects of artificial cardiac pacing, calcium chloride (CaCl2), and epinephrine in postcountershock asystole/bradycardia. Micromanometer catheters were positioned in the...

journal_title：Critical care medicine

authors： Niemann JT,Adomian GE,Garner D,Rosborough JP

更新日期：1985-09-01 00:00:00

abstract：:A polarographic conjunctival oxygen sensor was used to measure oxygen tension in a tissue bed supplied by the internal carotid artery. The shared vascular source of the conjunctiva and brain suggests that conjunctival PO2 monitoring may provide an index of cerebral perfusion. We studied the effects of hyperventilation...

journal_title：Critical care medicine

authors： Nisam M,Albertson TE,Panacek E,Rutherford W,Fisher CJ Jr

更新日期：1986-01-01 00:00:00

abstract：OBJECTIVE:Conventional outcomes research provides only percentage risk of such end points as mortality rate, utilization of resources, and/or broad groupings of multiple organ system dysfunction. These prognostications generally are not applicable to individual patients. The purpose of the present study was to determin...

journal_title：Critical care medicine

authors： Slotman GJ

更新日期：2002-05-01 00:00:00

abstract：PURPOSE:To determine the durability of the effects of a change in practice designed to promote the use of advanced supportive technology when it is of benefit but to limit its burdens when it is ineffective. We have reported that institution of a process of intensive communication reduced length of intensive care unit ...

journal_title：Critical care medicine

authors： Lilly CM,Sonna LA,Haley KJ,Massaro AF

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:Septic shock represents the major cause of infection-associated mortality in the intensive care unit. The possibility that combination antibiotic therapy of bacterial septic shock improves outcome is controversial. Current guidelines do not recommend combination therapy except for the express purpose of broa...

journal_title：Critical care medicine

authors： Kumar A,Zarychanski R,Light B,Parrillo J,Maki D,Simon D,Laporta D,Lapinsky S,Ellis P,Mirzanejad Y,Martinka G,Keenan S,Wood G,Arabi Y,Feinstein D,Kumar A,Dodek P,Kravetsky L,Doucette S,Cooperative Antimicrobial Thera

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVES:Given the efficacy and safety of recombinant human activated protein C (rhAPC) in the systemic inflammatory response syndrome, this study was designed to review the evidence for a role for APC in the pathogenesis of preeclampsia. Preeclampsia is a proinflammatory and procoagulant state, and it is a pregnancy...

journal_title：Critical care medicine

authors： von Dadelszen P,Magee LA,Lee SK,Stewart SD,Simone C,Koren G,Walley KR,Russell JA

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVE:To assess the number of adult critical care beds in Asian countries and regions in relation to population size. DESIGN:Cross-sectional observational study. SETTING:Twenty-three Asian countries and regions, covering 92.1% of the continent's population. PARTICIPANTS:Ten low-income and lower-middle-income eco...

journal_title：Critical care medicine

authors： Phua J,Faruq MO,Kulkarni AP,Redjeki IS,Detleuxay K,Mendsaikhan N,Sann KK,Shrestha BR,Hashmi M,Palo JEM,Haniffa R,Wang C,Hashemian SMR,Konkayev A,Mat Nor MB,Patjanasoontorn B,Nafees KMK,Ling L,Nishimura M,Al Bahrani

更新日期：2020-05-01 00:00:00

abstract：:We analyzed 35 samples of fresh frozen plasma (FFP), finding mean concentrations of 535 mg/dl glucose, 172 mEq/L sodium, 73 mEq/L chloride, 3.5 mEq/L potassium, 15 mEq/L bicarbonate, and 5.5 g/dl protein with 60% albumin. Thus, FFP is a hyperosmolal, hyperglycemic, hypernatremic, and hypochloremic solution which may b...

journal_title：Critical care medicine

authors： Ewalenko P,Deloof T,Peeters J

更新日期：1986-02-01 00:00:00

abstract：OBJECTIVES:Prone-position ventilation (PPV) induces acute improvement in oxygenation in many patients with acute respiratory distress syndrome (ARDS), with some maintaining their oxygenation even after they were returned to the supine position, but it is unclear what clinical factors determine the sustained oxygenation...

journal_title：Critical care medicine

authors： Lee DL,Chiang HT,Lin SL,Ger LP,Kun MH,Huang YC

更新日期：2002-07-01 00:00:00

abstract：CONTEXT:The results of studies on noninvasive positive pressure ventilation (NPPV) for acute hypoxemic respiratory failure unrelated to cardiogenic pulmonary edema have been inconsistent. OBJECTIVE:To assess the effect of NPPV on the rate of endotracheal intubation, intensive care unit and hospital length of stay, and...

journal_title：Critical care medicine

authors： Keenan SP,Sinuff T,Cook DJ,Hill NS

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVE:Blood loss and transfusion are frequent among patients undergoing liver surgery. Concerns have been raised about the safety and efficacy of transfusing stored blood. The influence of transfusing fresh vs. stored blood on the liver has not been studied to date. We tested the hypothesis that transfusion of stor...

journal_title：Critical care medicine

authors： Matot I,Katz M,Pappo O,Zelig O,Corchia N,Yedgar S,Barshtein G,Bennett-Guerrero E,Abramovitch R

更新日期：2013-03-01 00:00:00

abstract：:The metabolic support of critically ill patients is a relatively new topic of active research and discussion, and surprisingly little is known about the effects of critical illness on metabolic physiology and activity. The metabolic changes seen in critical illness are highly complex, and how and when to treat them ar...

journal_title：Critical care medicine

authors： Vincent JL

更新日期：2007-09-01 00:00:00

abstract：:Cardiogenic shock is the most common cause of death in patients hospitalized with acute myocardial infarction and is associated with a poor prognosis. More than 75% of cases are due to extensive left ventricular infarction and ventricular failure. Other causes include right ventricular infarction and papillary muscle ...

journal_title：Critical care medicine

authors： Topalian S,Ginsberg F,Parrillo JE

更新日期：2008-01-01 00:00:00

abstract：:The ICU has been considered a psychologically stressful environment. Although numerous studies have investigated this stress in ICU nurses, virtually none have examined how stressful the ICU is for physicians. This prospective study compares housestaff physicians' ratings of stress in the ICU to other medical-surgical...

journal_title：Critical care medicine

authors： Eisendrath SJ,Link N,Matthay M

更新日期：1986-02-01 00:00:00

abstract：OBJECTIVE:To examine the role of platelets, fibrin, and adhesion molecules in mediating neutrophil-endothelial cell interactions in septic shock. DESIGN:Controlled experiments using phase contrast microscopy to examine neutrophil, platelet, and endothelial cell interactions in flowing cell suspensions under simulated ...

journal_title：Critical care medicine

authors： Kirschenbaum LA,McKevitt D,Rullan M,Reisbeck B,Fujii T,Astiz ME

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVE:This survey was designed to study current practices in the monitoring and treatment of patients with severe head injury in the United States. DATA SOURCES:The collected data represent answers to telephone interviews of nurse managers, clinical specialists, and staff nurses specializing in neurotrauma care at...

journal_title：Critical care medicine

authors： Ghajar J,Hariri RJ,Narayan RK,Iacono LA,Firlik K,Patterson RH

更新日期：1995-03-01 00:00:00

abstract：OBJECTIVES:The contribution of individual immune response to Staphylococcus aureus bacteremia on outcome has not been well studied. The objective was to relate the host cytokine response to outcome of Staphylococcus aureus bacteremia. DESIGN:Prospective observational study. SETTING:Three U.S. university-affiliated me...

journal_title：Critical care medicine

authors： Minejima E,Bensman J,She RC,Mack WJ,Tuan Tran M,Ny P,Lou M,Yamaki J,Nieberg P,Ho J,Wong-Beringer A

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVES:Although highly active antiretroviral therapy has led to improved survival in HIV-infected individuals, outcomes for HIV-infected patients with sepsis in the post-highly active antiretroviral therapy era are conflicting. Access to highly active antiretroviral therapy and healthcare disparities continue to af...

journal_title：Critical care medicine

authors： Cribbs SK,Tse C,Andrews J,Shenvi N,Martin GS

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVES:A 2400-mOsm/L hypertonic solution (isosal) with a lower sodium content, compared with conventional 7.5% hypertonic saline, was formulated using a mixture of sodium chloride, glucose, and mixed amino acids. This solution was developed to minimize hypernatremia during resuscitation. We assessed the effects of ...

journal_title：Critical care medicine

authors： Sheikh AA,Matsuoka T,Wisner DH

更新日期：1996-07-01 00:00:00

abstract：OBJECTIVE:Chronic diabetes mellitus (DM) is a known cause of multisystem injury. The effect of DM in acute critical illness may also be detrimental, but is not specifically known. We hypothesized that the preexisting diagnosis of DM is an independent risk factor for mortality in critically ill patients. DESIGN:Paralle...

journal_title：Critical care medicine

authors： Graham BB,Keniston A,Gajic O,Trillo Alvarez CA,Medvedev S,Douglas IS

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:The high incidence of lower lobe collapse in adult intensive care patients is well described. We aimed to document the incidence and distribution of acute lobar collapse in the pediatric intensive care setting. The influence of anatomical and pathophysiological differences between the adult and pediatric resp...

journal_title：Critical care medicine

authors： Thomas K,Habibi P,Britto J,Owens CM

更新日期：1999-08-01 00:00:00