Intensive Care Society's Acute Physiology and Chronic Health Evaluation (APACHE II) study in Britain and Ireland: a prospective, multicenter, cohort study comparing two methods for predicting outcome for adult intensive care patients.

abstract：OBJECTIVE:To determine whether any advantage exists using racemic epinephrine instead of the more potent and less expensive levo(1)-epinephrine in the treatment of postextubation laryngeal edema. DESIGN:Prospective, double-blind, randomized study. SETTING:Pediatric intensive care unit in a university teaching hospita...

journal_title：Critical care medicine

authors： Nutman J,Brooks LJ,Deakins KM,Baldesare KK,Witte MK,Reed MD

更新日期：1994-10-01 00:00:00

abstract：OBJECTIVES:Studies have shown that endothelium-dependent relaxation (mediated by endothelium-derived nitric oxide) is depressed during the early, hyperdynamic stage of sepsis. Although it is known that ATP-MgCl2 produces beneficial effects following various adverse circulatory conditions, it remains unknown whether thi...

journal_title：Critical care medicine

authors： Wang P,Ba ZF,Cioffi WG,Bland KI,Chaudry IH

更新日期：1999-05-01 00:00:00

abstract：OBJECTIVE:After a stay in the intensive care unit, patients risk experiencing delusional memories, memory loss, and symptoms of posttraumatic stress. Since the 1990s, diaries have been kept for intensive care unit patients to help fill in memory gaps, aid psychosocial recovery, and improve health-related quality of lif...

journal_title：Critical care medicine

authors： Egerod I,Christensen D,Schwartz-Nielsen KH,Agård AS

更新日期：2011-08-01 00:00:00

abstract：:Paranasal sinusitis is reported as a complication of prolonged nasal intubation and the source of sepsis in adult intensive care patients. In surgical neonates with congenital malformations, prolonged intubation with a nasotracheal (NT) or NG tube is often necessary, but sinusitis with complicating sepsis is seldom re...

journal_title：Critical care medicine

authors： Bos AP,Tibboel D,Hazebroek FW,Hoeve H,Meradji M,Molenaar JC

更新日期：1989-09-01 00:00:00

abstract：OBJECTIVES:In-hospital pediatric sepsis mortality has decreased substantially, but long-term mortality and morbidity among children initially surviving sepsis, is unknown. Accordingly, the Life After Pediatric Sepsis Evaluation investigation was conducted to describe the trajectory of mortality and health-related quali...

journal_title：Critical care medicine

authors： Zimmerman JJ,Banks R,Berg RA,Zuppa A,Newth CJ,Wessel D,Pollack MM,Meert KL,Hall MW,Quasney M,Sapru A,Carcillo JA,McQuillen PS,Mourani PM,Wong H,Chima RS,Holubkov R,Coleman W,Sorenson S,Varni JW,McGalliard J,Haal

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVE:To determine the activation of nuclear factor-[kappa]B in peripheral blood CD14+ monocyte/macrophages and CD3+, CD4+, and CD8+ T cells in children with sepsis. DESIGN:Observational study. SETTING:University hospital. PATIENTS:Twenty-six children with sepsis (nine females and 17 males, aged between 10 days ...

journal_title：Critical care medicine

authors： Hotta N,Ichiyama T,Shiraishi M,Takekawa T,Matsubara T,Furukawa S

更新日期：2007-10-01 00:00:00

abstract：:The effects of hypertonic mannitol on postischemic cerebral circulation were studied in 20 dogs. Mannitol, 2 g/kg iv, was infused into ten dogs during a 2-h period starting 1.5 h after 6 min of complete cerebral ischemia. One hour postischemia, regional cerebral blood flow (rCBF) was 36% in the control group (ten dogs...

journal_title：Critical care medicine

authors： Arai T,Tsukahara I,Nitta K,Watanabe T

更新日期：1986-07-01 00:00:00

abstract：OBJECTIVE:The Sequential Organ Failure Assessment (SOFA) score was developed to quantify the severity of patients' illness, based on the degree of organ dysfunction. This study aimed to evaluate the accuracy and the reliability of SOFA scoring. DESIGN:Prospective study. SETTING:Adult intensive care unit (ICU) in a te...

journal_title：Critical care medicine

authors： Arts DG,de Keizer NF,Vroom MB,de Jonge E

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVE:Limited data are available on the influence of sedation for critical care therapy with the widely used anesthetic propofol on recovery from acute traumatic brain injury. To establish the influence of propofol on endogenous neurogenesis and functional recovery after traumatic brain injury, rats were sedated wi...

journal_title：Critical care medicine

authors： Thal SC,Timaru-Kast R,Wilde F,Merk P,Johnson F,Frauenknecht K,Sebastiani A,Sommer C,Staib-Lasarzik I,Werner C,Engelhard K

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:The renal effects of dopamine in critically ill patients remain controversial. Low-dose dobutamine has been reported to improve renal function. We compared the effects of various doses of dopamine and dobutamine on renal function in critically ill patients. DESIGN:Prospective, single-blind, randomized study....

journal_title：Critical care medicine

authors： Ichai C,Soubielle J,Carles M,Giunti C,Grimaud D

更新日期：2000-04-01 00:00:00

abstract：PURPOSE:Periodic diagnostic tests and continuous and intermittent monitoring are integral to critical care medicine. The focus of this article is understanding the impact of existing diagnostic technology, as well as that of new diagnostic technology. DATA SYNTHESIS:We use literature about gastric tonometry to illustr...

journal_title：Critical care medicine

authors： Keenan SP,Guyatt GH,Sibbald WJ,Cook DJ,Heyland DK,Jaeschke RZ

更新日期：1999-09-01 00:00:00

abstract：OBJECTIVES:To compare the incidence of withdrawal or withholding of life support (WD/WHLS), and to identify similarities and differences in the process of the withdrawal of life support (WDLS) between teaching and community hospitals' intensive care units (ICUs). DESIGN:Prospective cohort study, with some data obtaine...

journal_title：Critical care medicine

authors： Keenan SP,Busche KD,Chen LM,Esmail R,Inman KJ,Sibbald WJ

更新日期：1998-02-01 00:00:00

abstract：:Perfluorocarbon (PFC) emulsions are promising oxygen-carrying blood supplements for the treatment of shock and in organ preservation for transplantation. We used the isolated, blood-perfused, canine right lower lung lobe (RLL) to determine the effect of a PFC emulsion, Oxypherol (FC-43), upon lung fluid balance and he...

journal_title：Critical care medicine

authors： Hall JE,Ehrhart IC,Hofman WF

更新日期：1985-12-01 00:00:00

abstract：:Arterial oxygen saturation, determined noninvasively by pulse oximetry in 32 pediatric patients with cyanotic congenital heart disease (CHD), was compared with oxygen saturation measured by a cooximeter in simultaneously obtained arterial blood samples. The patients were studied in the cardiac catheterization laborato...

journal_title：Critical care medicine

authors： Boxer RA,Gottesfeld I,Singh S,LaCorte MA,Parnell VA Jr,Walker P

更新日期：1987-11-01 00:00:00

abstract：OBJECTIVE:The effect of levosimendan, a novel inotropic vasodilator (inodilator), on the microvascular gastric mucosal hemoglobin oxygenation (muHbo(2)) is unknown. A possible effect could thereby be selective for the splanchnic region or could primarily reflect changes in systemic oxygen transport (Do(2)) and/or oxyge...

journal_title：Critical care medicine

authors： Schwarte LA,Picker O,Bornstein SR,Fournell A,Scheeren TW

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVES:Clinical providers have access to a number of pharmacologic agents during in-hospital cardiac arrest. Few studies have explored medication administration patterns during in-hospital cardiac arrest. Herein, we examine trends in use of pharmacologic interventions during in-hospital cardiac arrest both over tim...

journal_title：Critical care medicine

authors： Moskowitz A,Ross CE,Andersen LW,Grossestreuer AV,Berg KM,Donnino MW,American Heart Association’s Get With The Guidelines – Resuscitation Investigators.

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVES:Neurologic damage following cardiac arrest remains a major burden for modern resuscitation medicine. Cardiopulmonary resuscitation with extracorporeal circulatory support holds the potential to reduce morbidity and mortality. Furthermore, the endogenous gasotransmitter carbon monoxide attracts attention in r...

journal_title：Critical care medicine

authors： Wollborn J,Steiger C,Doostkam S,Schallner N,Schroeter N,Kari FA,Meinel L,Buerkle H,Schick MA,Goebel U

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVES:To review the immunologic role of the cytokines and the specific role that tumor necrosis factor (TNF) plays in response to infection. The influence of bacterial lipopolysaccharide on TNF, the cytokine cascade, and resultant pathologies are also reviewed. DATA SOURCES:A MEDLINE search of the international E...

journal_title：Critical care medicine

authors： Beutler B,Grau GE

更新日期：1993-10-01 00:00:00

abstract：:The aim of this study was to assess prospectively the variations of serum phosphorus concentration (P) after onset of mechanical ventilation (MV) in patients with chronic obstructive pulmonary disease (COPD) and acute respiratory acidosis. In 14 COPD patients, we measured P, PaCO2, and pH, immediately before MV (H0), ...

journal_title：Critical care medicine

authors： Laaban JP,Grateau G,Psychoyos I,Laromiguière M,Vuong TK,Rochemaure J

更新日期：1989-11-01 00:00:00

abstract：OBJECTIVES:Peripherally inserted central catheters are increasingly used in ICU as an alternative to centrally inserted central catheters for IV infusion. However, their reliability for hemodynamic measurements with transpulmonary thermodilution is currently unknown. We investigated the agreement between transpulmonary...

journal_title：Critical care medicine

authors： D'Arrigo S,Sandroni C,Cacciola S,Dell'Anna AM,Pittiruti M,Annetta MG,Colosimo C,Antonelli M

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:To study the importance of endothelin-1-induced vasoconstriction in a model of acute and maintained low cardiac output, by investigating regional changes within the mesenteric and particularly the intestinal mucosal circulation. DESIGN:Prospective, controlled animal study. SETTING:University-affiliated rese...

journal_title：Critical care medicine

authors： Burgener D,Laesser M,Treggiari-Venzi M,Oi Y,Jolliet P,Strasser S,Hadengue A,Aneman A

更新日期：2001-08-01 00:00:00

abstract：OBJECTIVES:To describe the timing of onset of organ system failure, multiple organ system failure diagnosis, and the subsequent death in children admitted to a pediatric intensive care unit (ICU). Second, to identify independent risk markers of death in pediatric patients with multiple organ system failure. DESIGN:Rev...

journal_title：Critical care medicine

authors： Proulx F,Gauthier M,Nadeau D,Lacroix J,Farrell CA

更新日期：1994-06-01 00:00:00

abstract：OBJECTIVE:Conventional outcomes research provides only percentage risk of such end points as mortality rate, utilization of resources, and/or broad groupings of multiple organ system dysfunction. These prognostications generally are not applicable to individual patients. The purpose of the present study was to determin...

journal_title：Critical care medicine

authors： Slotman GJ

更新日期：2002-05-01 00:00:00

abstract：OBJECTIVES:To characterize the rates of accidental removal of endotracheal tubes, nasogastric tubes, central venous catheters, and arterial catheters. To assess the efficacy of corrective measures aimed at reducing the accidental removal of these devices. DESIGN:Prospective, observational, and interventional study. S...

journal_title：Critical care medicine

authors： Carrión MI,Ayuso D,Marcos M,Paz Robles M,de la Cal MA,Alía I,Esteban A

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the relationship of patient care variables to survival and functional outcome in the pediatric population with traumatic brain injury. DESIGN:Retrospective chart review. SETTING:A 16-bed pediatric critical care unit in an academic community children's hospital. PATIENT...

journal_title：Critical care medicine

authors： Hackbarth RM,Rzeszutko KM,Sturm G,Donders J,Kuldanek AS,Sanfilippo DJ

更新日期：2002-07-01 00:00:00

abstract：OBJECTIVE:To determine if autopsies performed on patients who die in the medical intensive care unit (ICU) provide clinically important new information. DESIGN:Retrospective review. SETTING:A 16-bed medical-coronary ICU. PATIENTS:Patients who underwent autopsy during a 1-yr period. INTERVENTIONS:Pre mortem diagnose...

journal_title：Critical care medicine

authors： Blosser SA,Zimmerman HE,Stauffer JL

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND:Although survival is traditionally modeled using Cox proportional hazards modeling, this approach may be inappropriate in sepsis, in which the proportional hazards assumption does not hold. Newer, more flexible models, such as Gray's model, may be more appropriate. OBJECTIVES:To construct and compare Gray's...

journal_title：Critical care medicine

authors： Kasal J,Jovanovic Z,Clermont G,Weissfeld LA,Kaplan V,Watson RS,Angus DC

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVES:Extracellular mitochondrial DNA and N-formyl peptides released following tissue damage may contribute to systemic inflammation through stimulation of the innate immune system. In this review, we evaluate existing in vivo human data regarding a role for mitochondrial DNA and N-formyl peptides in producing sys...

journal_title：Critical care medicine

authors： Lubkin DT,Bishawi M,Barbas AS,Brennan TV,Kirk AD

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:Acute renal failure can be treated with continuous renal replacement therapy (CRRT) or intermittent hemodialysis. There is no difference in mortality, although patients treated with CRRT may have a higher rate of renal recovery. Given these considerations, an estimate of the costs by modality may help in choo...

journal_title：Critical care medicine

authors： Manns B,Doig CJ,Lee H,Dean S,Tonelli M,Johnson D,Donaldson C

更新日期：2003-02-01 00:00:00

abstract：:Ventricular fibrillation (VF) can masquerade as asystole. We report a 54-yr-old male in cardiac arrest who, on surface ECG, appeared to be in VF or asystole. A bedside intracardiac recording using a transmyocardial pacing wire showed the true rhythm to be atrial fibrillation (AF) with high grade atrioventricular block...

journal_title：Critical care medicine

authors： Ornato JP,Gonzales ER,Garnett R

更新日期：1987-04-01 00:00:00