Effect of Boarding on Mortality in ICUs.

abstract：:Pulmonary barotrauma developed in 18/430 patients receiving respirator support for longer than 12 hours. Pneumothorax occurred in 15 of these patients and was treated with tube thoracostomy and 15-20 cm H2O pleural suction. Full reexpansion of the lungs were achieved in all but three patients, two of whom had bronchop...

journal_title：Critical care medicine

authors： Zimmerman JE,Dunbar BS,Klingenmaier CH

更新日期：1975-03-01 00:00:00

abstract：:Human hemoglobin (Hb) solution is being developed for use as an oxygen-delivering resuscitation fluid. Substantial improvements in the general purity and quality of experimental Hb solutions have been achieved by recent research efforts. Hb solutions now appear to be free of the undesirable biological effects that wer...

journal_title：Critical care medicine

authors： DeVenuto F

更新日期：1982-04-01 00:00:00

abstract：OBJECTIVE:To compare prone positioning and continuous rotational therapy with respect to oxygenation and hemodynamics in patients suffering from adult respiratory distress syndrome (ARDS). DESIGN:Randomized, prospective pilot study. SETTING:Intensive care unit at a university hospital. PATIENTS:Twenty-six mechanical...

journal_title：Critical care medicine

authors： Staudinger T,Kofler J,Müllner M,Locker GJ,Laczika K,Knapp S,Losert H,Frass M

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the occurrence of complications and patient deteriorations during the air and ground transportation of intubated pediatric patients, performed by a nonphysician-based team under the direction of an intensive care attending physician or fellow. DESIGN:Retrospective chart review. SETTING:A 600-bed...

journal_title：Critical care medicine

authors： Beyer AJ 3rd,Land G,Zaritsky A

更新日期：1992-07-01 00:00:00

abstract：OBJECTIVE:To describe a case of hepatic subcapsular hematoma causing an acute Budd-Chiari-like syndrome, leading to hepatic compartment syndrome, which combines compression of intrahepatic vessels on CT, acute liver failure, and refractory shock. DESIGN:Case report. SETTING:Surgical ICU of a university teaching hospi...

journal_title：Critical care medicine

authors： Marcaire F,Malavieille F,Pichot-Delahaye V,Floccard B,Rimmelé T

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVES:A 2400-mOsm/L hypertonic solution (isosal) with a lower sodium content, compared with conventional 7.5% hypertonic saline, was formulated using a mixture of sodium chloride, glucose, and mixed amino acids. This solution was developed to minimize hypernatremia during resuscitation. We assessed the effects of ...

journal_title：Critical care medicine

authors： Sheikh AA,Matsuoka T,Wisner DH

更新日期：1996-07-01 00:00:00

abstract：OBJECTIVE:Cerebral perfusion pressure<40 mm Hg following pediatric traumatic brain injury has been associated with increased mortality independent of age, and current guidelines recommend maintaining cerebral perfusion pressure between 40 mm Hg-60 mm Hg. Although adult traumatic brain injury studies have observed an in...

journal_title：Critical care medicine

authors： Friess SH,Smith C,Kilbaugh TJ,Frangos SG,Ralston J,Helfaer MA,Margulies SS

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:Anesthetic preconditioning appears to be a viable strategy to treat ischemic cerebral injury. Here we investigated 1) whether the protection conferred by sevoflurane preconditioning sustains in time; 2) whether sevoflurane preconditioning diminishes mitochondrial dysfunction following cerebral ischemia; and 3...

journal_title：Critical care medicine

authors： Ye R,Yang Q,Kong X,Li N,Zhang Y,Han J,Xiong L,Liu X,Zhao G

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVE:To compare the ability of two methods--Acute Physiology and Chronic Health Evaluation (APACHE II) and Mortality Prediction Model (MPM)--to predict hospital outcome for a large group of intensive care patients from Britain and Ireland. DESIGN:Prospective, multicenter, cohort study. SETTING:Twenty-six general...

journal_title：Critical care medicine

authors： Rowan KM,Kerr JH,Major E,McPherson K,Short A,Vessey MP

更新日期：1994-09-01 00:00:00

abstract：OBJECTIVE:Intravesical pressure measurement is considered to be the gold standard for the assessment of intra-abdominal pressure. However, this method is indirect and depends on a physiologic bladder function. We evaluated a modified piezoresistive technique and a water-capsule technique for direct and continuous intra...

journal_title：Critical care medicine

authors： Schachtrupp A,Henzler D,Orfao S,Schaefer W,Schwab R,Becker P,Schumpelick V

更新日期：2006-03-01 00:00:00

abstract：:The pericardium serves many important functions, but it is not essential for life. Pericardial heart disease comprises only pericarditis and its complications, tamponade and constriction, and congenital lesions. However, the pericardium is affected by virtually every category of disease. The critical care physician is...

journal_title：Critical care medicine

authors： Hoit BD

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVES:Despite the common occurrence of brain injury in patients undergoing extracorporeal membrane oxygenation, it is unclear which cannulation method carries a higher risk of brain injury. We compared the prevalence of brain injury between patients undergoing venoarterial and venovenous extracorporeal membrane ox...

journal_title：Critical care medicine

authors： Shoskes A,Migdady I,Rice C,Hassett C,Deshpande A,Price C,Hernandez AV,Cho SM

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVES:We aimed to implement our Smart Use of Antibiotics Program to ensure the proper use of antimicrobials, improve patient care and outcomes, and reduce the risks of adverse effects and antimicrobial resistance. DESIGN:We compared the time periods before (baseline) and after (intervention) the implementation of...

journal_title：Critical care medicine

authors： Lu C,Liu Q,Yuan H,Wang L

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND AND METHODS:This study was designed to explore the effect of mild cerebral and systemic hypothermia (34 degrees C) on outcome after prolonged cardiac arrest in dogs. After ventricular fibrillation with no flow of 10 min, and standard external CPR with epinephrine (low flow) from ventricular fibrillation time...

journal_title：Critical care medicine

authors： Sterz F,Safar P,Tisherman S,Radovsky A,Kuboyama K,Oku K

更新日期：1991-03-01 00:00:00

abstract：OBJECTIVE:Recent studies have demonstrated the therapeutic effectiveness and pharmacologic mechanisms of hyperbaric oxygen therapy (HBOT) in the treatment of a systemic shock state. To elucidate the in vivo role of HBOT during sepsis, we evaluated the effects of HBOT on intestinal mucosal injury and bacterial transloca...

journal_title：Critical care medicine

authors： Sakoda M,Ueno S,Kihara K,Arikawa K,Dogomori H,Nuruki K,Takao S,Aikou T

更新日期：2004-08-01 00:00:00

abstract：OBJECTIVE:Clinical trial designs that randomize patients to fixed treatment regimens may disrupt preexisting relationships between illness severity and level of therapy. The practice misalignments created by such designs may have unintended effects on trial results and safety. METHODS:To illustrate this problem, the T...

journal_title：Critical care medicine

authors： Deans KJ,Minneci PC,Suffredini AF,Danner RL,Hoffman WD,Ciu X,Klein HG,Schechter AN,Banks SM,Eichacker PQ,Natanson C

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVE:Supplementation with tetrahydrobiopterin, a nitric oxide synthase cofactor, may reduce microvascular endothelial dysfunction in severe sepsis. We studied whether tetrahydrobiopterin administration exerts beneficial effects in an ovine septic shock model. DESIGN:Randomized animal study. SETTING:University ho...

journal_title：Critical care medicine

authors： He X,Su F,Velissaris D,Salgado DR,de Souza Barros D,Lorent S,Taccone FS,Vincent JL,De Backer D

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:To assess the efficacy of bulk diffusion in maintaining oxygenation during apnea testing for brain death. DESIGN:Case series. SETTING:ICU in a primary care hospital. PATIENTS:Twenty-four consecutive patients with suspected brain death. Most patients suffered cerebral trauma from vehicular accidents. INTER...

journal_title：Critical care medicine

authors： al Jumah M,McLean DR,al Rajeh S,Crow N

更新日期：1992-11-01 00:00:00

abstract：:Biological systems are innately complex, display nonlinear behavior, and respond to both disease and its treatment in similar complex ways. Complex systems display self-organization and predictive behavior along a range of possible states, often referred to as chaotic behavior, and can be both characterized and quanti...

journal_title：Critical care medicine

authors： Pinsky MR

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:Mannitol is widely used in hospitals worldwide to treat patients with high intracranial pressure and/or cerebral edema. One of the mechanisms by which mannitol is thought to affect intracranial pressure is by increasing the patient's serum osmolarity, but not the osmolarity in the brain or cerebrospinal fluid...

journal_title：Critical care medicine

authors： Polderman KH,van de Kraats G,Dixon JM,Vandertop WP,Girbes AR

更新日期：2003-02-01 00:00:00

abstract：OBJECTIVES:In the Acute Respiratory Distress Syndrome Network randomized controlled trial, methylprednisolone treatment was associated with increased return to mechanical ventilation with partial loss of early improvements. We hypothesize a causal relationship between protocol-driven rapid discontinuation of methylpred...

journal_title：Critical care medicine

authors： Meduri GU,Bridges L,Siemieniuk RAC,Kocak M

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVES:To evaluate the impact of a comprehensive unit-based safety program on safety climate in a large cohort of intensive care units participating in the Keystone intensive care unit project. DESIGN/SETTING:A prospective cohort collaborative study to improve quality of care and safety culture by implementing and...

journal_title：Critical care medicine

authors： Sexton JB,Berenholtz SM,Goeschel CA,Watson SR,Holzmueller CG,Thompson DA,Hyzy RC,Marsteller JA,Schumacher K,Pronovost PJ

更新日期：2011-05-01 00:00:00

abstract：:Seizures in the neonatal period are usually concomitants of serious neurological disease. The convulsive phenomena take certain distinctive and often subtle forms because of the status of the neuroanatomical and neurophysiological development of the neonatal brain. The predominant etiological process is hypoxic-ischem...

journal_title：Critical care medicine

authors： Volpe JJ

更新日期：1977-01-01 00:00:00

abstract：OBJECTIVE:To determine xanthine oxidase activity, free radical concentrations, and lipid peroxidation in patients with sepsis syndrome compared with noninfected critically ill patients. DESIGN:A prospective observational study. SETTING:A nine-bed intensive care unit in a university teaching hospital trust. PATIENTS:...

journal_title：Critical care medicine

authors： Galley HF,Davies MJ,Webster NR

更新日期：1996-10-01 00:00:00

abstract：:End tidal CO2 tension (PetCO2) and transcutaneous CO2 tension (PtcCO2) were compared with arterial CO2 (PaCO2) before and after withdrawal of mechanical ventilation in 20 patients predisposed to hypercarbia. With stable PaCO2 during mechanical ventilation, the correlation coefficient (r) between PaCO2 and PetCO2 was ....

journal_title：Critical care medicine

authors： Healey CJ,Fedullo AJ,Swinburne AJ,Wahl GW

更新日期：1987-08-01 00:00:00

abstract：:We used metoprolol orally or iv in 25 patients with multifocal atrial tachycardia that was complicating severe cardiopulmonary illness, and we observed its effect on heart rate and rhythm, BP, and arterial blood gases. All patients showed a dramatic slowing of heart rate, averaging 54.0 +/- 4.0 beat/min (p less than ....

journal_title：Critical care medicine

authors： Hazard PB,Burnett CR

更新日期：1987-01-01 00:00:00

abstract：:The records of 101 drowning or near-drowning victims admitted to Children's Hospital of Los Angeles (CHLA) between January 1975 and June 1978 were reviewed. The admission Glasgow coma score could be assigned retrospectively to 94 patients. A low score (less than 5) predicted a high risk group of patients with 80% mort...

journal_title：Critical care medicine

authors： Dean JM,Kaufman ND

更新日期：1981-07-01 00:00:00

abstract：OBJECTIVES:Vascular beds vary in their responses to atrial natriuretic peptide and sodium nitroprusside. Both of these agents dilate blood vessels by increasing intracellular guanosine 3',5'-cyclic monophosphate (cyclic-GMP) but activate different enzymes in the vascular smooth muscle cell. We aimed to determine if the...

journal_title：Critical care medicine

authors： Zhang LM,Castresana M,Newman WH

更新日期：1994-09-01 00:00:00

abstract：OBJECTIVE:Anemia increases risk of bleeding complications in the critically ill. In primary intracerebral hemorrhage (ICH), the most fatal type of stroke, outcome is largely dependent on the volume of hemorrhage into the brain. We investigated the relationship between anemia and clinical course of acute ICH. METHODS:S...

journal_title：Critical care medicine

authors： Kumar MA,Rost NS,Snider RW,Chanderraj R,Greenberg SM,Smith EE,Rosand J

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:Neutrophils are an important component of the inflammatory response that characterizes acute lung injury (ALI). This discussion aims to review the contribution of neutrophils to the development and progression of ALI and to highlight the major intracellular signaling pathways that are involved in neutrophil a...

journal_title：Critical care medicine

authors： Abraham E

更新日期：2003-04-01 00:00:00