Sex-based differences in serum cardiac troponin I, a specific marker for myocardial injury, after cardiac surgery.

abstract：OBJECTIVES:To develop a valid, reliable measure that reflected the environment of respectfulness within the ICU setting. DESIGN:We developed a preliminary survey instrument based on conceptual domains of respect identified through prior qualitative analyses of ICU patient, family member, and clinician perspectives. Th...

journal_title：Critical care medicine

authors： Beach MC,Topazian R,Chan KS,Sugarman J,Geller G

更新日期：2018-06-01 00:00:00

abstract：:Cerebral arteriovenous differences in oxygen content [C(a-v)O2] and glucose content [C(a-v)gluc] were used to predict outcome in 20 patients who remained comatose after resuscitation for cardiopulmonary arrest. Cerebral prognosis was good when C(a-v)O2 values were greater than 1.8 mMol/L and the oxygen glucose index (...

journal_title：Critical care medicine

authors： Ducassé JL,Marc-Vergnes JP,Cathala B,Genestal M,Lareng L

更新日期：1984-10-01 00:00:00

abstract：OBJECTIVE:This study evaluates the ability of perflubron to inhibit pulmonary neutrophil accumulation during partial liquid ventilation (PLV) in the setting of acute lung injury. DESIGN:Randomized, controlled, nonblinded study. SETTING:Research laboratory at a university. SUBJECTS:Male, Sprague-Dawley rats (n = 120,...

journal_title：Critical care medicine

authors： Colton DM,Till GO,Johnson KJ,Dean SB,Bartlett RH,Hirschl RB

更新日期：1998-10-01 00:00:00

abstract：OBJECTIVE:To examine the role of platelets, fibrin, and adhesion molecules in mediating neutrophil-endothelial cell interactions in septic shock. DESIGN:Controlled experiments using phase contrast microscopy to examine neutrophil, platelet, and endothelial cell interactions in flowing cell suspensions under simulated ...

journal_title：Critical care medicine

authors： Kirschenbaum LA,McKevitt D,Rullan M,Reisbeck B,Fujii T,Astiz ME

更新日期：2004-09-01 00:00:00

abstract：:Cardiac arrest has a poor prognosis, regardless of age group. Children who fail to respond to two standard doses of epinephrine (0.01 mg/kg) rarely survive to hospital discharge, and most die without the return of spontaneous circulation (ROSC). We treated seven consecutive children in cardiac arrest with high dose ep...

journal_title：Critical care medicine

authors： Goetting MG,Paradis NA

更新日期：1989-12-01 00:00:00

abstract：:To understand better the incidence and meaning of hyperamylasemia in the intensive care setting, cellulose acetate membrane electrophoresis was used to measure the isoenzymes of serum amylase in 192 patients with a variety of critical illnesses. Seventy of these patients had elevated serum amylase levels, but none had...

journal_title：Critical care medicine

authors： Weaver DW,Busuito MJ,Bouwman DL,Wilson RF

更新日期：1985-07-01 00:00:00

abstract：OBJECTIVE:To date, no study has systematically investigated the impact of drowning-induced asphyxia on hemostasis. Our objective was to test the hypothesis that asphyxia induces bleeding by hyperfibrinolytic disseminated intravascular coagulation. DESIGN:Observational study. SETTING:A 2,100-bed tertiary care facility...

journal_title：Critical care medicine

authors： Schwameis M,Schober A,Schörgenhofer C,Sperr WR,Schöchl H,Janata-Schwatczek K,Kürkciyan EI,Sterz F,Jilma B

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVES:Prone-position ventilation (PPV) induces acute improvement in oxygenation in many patients with acute respiratory distress syndrome (ARDS), with some maintaining their oxygenation even after they were returned to the supine position, but it is unclear what clinical factors determine the sustained oxygenation...

journal_title：Critical care medicine

authors： Lee DL,Chiang HT,Lin SL,Ger LP,Kun MH,Huang YC

更新日期：2002-07-01 00:00:00

abstract：OBJECTIVE:To develop a pharmacokinetic-pharmacogenomic population model of morphine in critically ill children with acute respiratory failure. DESIGN:Prospective pharmacokinetic-pharmacogenomic observational study. SETTING:Thirteen PICUs across the United States. PATIENTS:Pediatric subjects (n = 66) mechanically ven...

journal_title：Critical care medicine

authors： Zuppa AF,Benitez GR,Zane NR,Curley MAQ,Bradfield J,Hakonarson H,Gastonguay MS,Moorthy G,Prodell J,Gastonguay MR

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVES:We reviewed randomized trials of adult ICU patients of interventions hypothesized to reduce delirium burden to determine whether interventions that are more effective at reducing delirium duration are associated with a reduction in short-term mortality. DATA SOURCES:We searched CINHAHL, EMBASE, MEDLINE, and...

journal_title：Critical care medicine

authors： Al-Qadheeb NS,Balk EM,Fraser GL,Skrobik Y,Riker RR,Kress JP,Whitehead S,Devlin JW

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVES:To investigate family perceptions of having a nurse participating in family conferences and to assess the psychologic well being of the same families after ICU discharge. DESIGN:Mixed-method design with a qualitative study embedded in a single-center randomized study. SETTING:Twelve-bed medical-surgical IC...

journal_title：Critical care medicine

authors： Garrouste-Orgeas M,Max A,Lerin T,Grégoire C,Ruckly S,Kloeckner M,Brochon S,Pichot E,Simons C,El-Mhadri M,Bruel C,Philippart F,Fournier J,Tiercelet K,Timsit JF,Misset B

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVES:To perform a complete immunological characterization of compensatory anti-inflammatory response syndrome in patients with sepsis and to explore the relationship between these changes and clinical outcomes of 28-day mortality and secondary infections. DESIGN:Prospective single-center study conducted between ...

journal_title：Critical care medicine

authors： Gomez HG,Gonzalez SM,Londoño JM,Hoyos NA,Niño CD,Leon AL,Velilla PA,Rugeles MT,Jaimes FA

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:To test the reliability and validity of a modified moral distress tool, originally developed for the nursing profession, on respiratory care practitioners. To describe the relationship between moral distress, career dissatisfaction, and job turnover in respiratory care. DESIGN:A 28-question survey was develo...

journal_title：Critical care medicine

authors： Schwenzer KJ,Wang L

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that hyperbaric oxygen therapy ameliorates delayed cognitive impairment after acute carbon monoxide poisoning by promoting neurogenesis through upregulating the brain-derived neurotrophic factor in the hippocampus. DESIGN:Laboratory animal experiments. SETTING:University/Medical cente...

journal_title：Critical care medicine

authors： Liu WC,Yang SN,Wu CW,Chen LW,Chan JY

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVES:To evaluate knowledge translation after publication of the target temperature management 33°C versus 36°C after out-of-hospital cardiac arrest trial and associated patient outcomes. Our primary hypothesis was that target temperature management at 36°C was rapidly adopted in Australian and New Zealand ICUs. S...

journal_title：Critical care medicine

authors： Salter R,Bailey M,Bellomo R,Eastwood G,Goodwin A,Nielsen N,Pilcher D,Nichol A,Saxena M,Shehabi Y,Young P,Australian and New Zealand Intensive Care Society Centre for Outcome and Resource Evaluation (ANZICS-CORE).

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:To compare the effects of continuous negative extrathoracic pressure (CNEP) and positive end-expiratory pressure (PEEP) at the same level of transpulmonary pressure. DESIGN:Prospective analysis. SETTING:Medical intensive care unit of a university hospital. PATIENTS:Nine consecutive acute lung injury patien...

journal_title：Critical care medicine

authors： Borelli M,Benini A,Denkewitz T,Acciaro C,Foti G,Pesenti A

更新日期：1998-06-01 00:00:00

abstract：OBJECTIVES:The objectives of the present study were to evaluate, in patients with persistent arterial hypotension in the immediate postcardiac surgery period, the effects of norepinephrine infusion on ventriculo-arterial coupling, its determinants: arterial elastance and end-systolic ventricular elastance, and to test ...

journal_title：Critical care medicine

authors： Guinot PG,Longrois D,Kamel S,Lorne E,Dupont H

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:To investigate the concentrations of reduced and total glutathione in relation to the muscle free amino acid pattern in critically ill patients and matched healthy controls. DESIGN:Prospective case control. SETTING:University hospital intensive care unit (ICU). PATIENTS:Eleven critically ill patients in th...

journal_title：Critical care medicine

authors： Hammarqvist F,Luo JL,Cotgreave IA,Andersson K,Wernerman J

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVE:To evaluate whether current criteria for the diagnosis of brain death fulfill the requirement for the "irreversible cessation of all functions of the entire brain, including the brainstem." DATA SOURCES:Clinical, philosophical, legal, and public policy literature on the subject of brain death. DATA EXTRACTI...

journal_title：Critical care medicine

authors： Truog RD,Fackler JC

更新日期：1992-12-01 00:00:00

abstract：OBJECTIVE:To analyze the effects of an extracorporeal bioartificial liver containing alginate bead-entrapped hepatocytes on pigs with ischemia-induced acute hepatic failure. DESIGN:Prospective animal study. SETTING:University and INSERM laboratory. SUBJECTS:Fifteen Large White/Pietrin female pigs weighing 20-30 kg. ...

journal_title：Critical care medicine

authors： Desille M,Mahler S,Seguin P,Mallédant Y,Frémond B,Sébille V,Bouix A,Desjardins JF,Joly A,Desbois J,Lebreton Y,Campion JP,Clément B

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVE:To assess the effectiveness of routine intensive care unit surveillance compared with frequent 12-lead electrocardiogram monitoring for detecting electrocardiogram evidence suggestive of prolonged myocardial ischemia in vascular surgery patients. DESIGN:Prospective cohort trial. SETTING:Intensive care unit....

journal_title：Critical care medicine

authors： Martinez EA,Kim LJ,Faraday N,Rosenfeld B,Bass EB,Perler BA,Williams GM,Dorman T,Pronovost PJ

更新日期：2003-09-01 00:00:00

abstract：:A total of 2711 pulmonary artery wedge pressure (WP) measurement attempts were made prospectively from WP recordings in 44 (30 men) critically ill patients, using 77 flow-directed catheters. Of these, 322 (12%) failed to yield a WP measurement, and 521 (18%) were associated with technical problems. One half of these t...

journal_title：Critical care medicine

authors： Morris AH,Chapman RH,Gardner RM

更新日期：1984-03-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to determine the prognostic value of sublingual PCO2 (P(SL)CO2), lactate concentration, and mixed venous oxygen saturation (S(MV)O2) in hemodynamically unstable intensive care patients and, additionally, to compare the temporal changes of these variables in response to treatment....

journal_title：Critical care medicine

authors： Marik PE,Bankov A

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVE:Failure to detect clinical deterioration in the hospital is common and associated with poor patient outcomes and increased healthcare costs. Our objective was to evaluate the feasibility and accuracy of real-time risk stratification using the electronic Cardiac Arrest Risk Triage score, an electronic health r...

journal_title：Critical care medicine

authors： Kang MA,Churpek MM,Zadravecz FJ,Adhikari R,Twu NM,Edelson DP

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVES:To assess whether sepsis-associated coagulopathy predicts hospital mortality. DESIGN:Retrospective cohort study. SETTING:One-thousand three-hundred beds urban academic medical center. PATIENTS:Six-thousand one-hundred forty-eight consecutive patients hospitalized between January 1, 2010, and December 31, ...

journal_title：Critical care medicine

authors： Lyons PG,Micek ST,Hampton N,Kollef MH

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:Transfusion of red blood cells has been linked to disappointing clinical outcomes in the critically ill, but specific mechanisms of organ dysfunction after transfusion remain poorly understood. We tested the hypothesis that red blood cell storage impairs the ability of red blood cells to release adenosine-5'-...

journal_title：Critical care medicine

authors： Zhu H,Zennadi R,Xu BX,Eu JP,Torok JA,Telen MJ,McMahon TJ

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVE:The flow rate of a liquid drainage from the lungs is limited because of the elastic nature of the airways. This study was designed to clarify the relationship between intrapulmonary liquid volume and the development of the flow limitation or choked flow phenomenon as a function of expiratory flow rate during ...

journal_title：Critical care medicine

authors： Baba Y,Brant D,Brah SS,Grotberg J,Bartlett RH,Hirschl RB

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND AND METHODS:The development of a multifactorial coagulopathy after massive transfusion is a well-recognized clinical problem that is almost always accompanied by hypothermia. The purpose of this study was to investigate the isolated effect of alterations of temperature on the integrity of the coagulation cas...

journal_title：Critical care medicine

authors： Rohrer MJ,Natale AM

更新日期：1992-10-01 00:00:00

abstract：OBJECTIVE:Persistent pulmonary hypertension of the newborn is characterized by the presence of intense vasoconstriction and vascular remodeling. Protein tyrosine phosphorylation has been recognized as a critical regulatory element in signal transduction, because it is dynamically regulated by the opposing actions of pr...

journal_title：Critical care medicine

authors： Berkenbosch JW,Baribeau J,Ferretti E,Perreault T

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVES:To describe the physiologic mechanisms of ventilator-induced lung injury and to define the major ventilator and host-dependent risk factors that contribute to such injury. DATA SOURCE:Basic science and clinical studies related to ventilator-induced barotrauma and lung pathophysiology. STUDY SELECTION:Empha...

journal_title：Critical care medicine

authors： Parker JC,Hernandez LA,Peevy KJ

更新日期：1993-01-01 00:00:00