Assessment of creatinine clearance in intensive care patients.

abstract：OBJECTIVE:To determine if selective decontamination of the digestive tract (SDD) influences the proinflammatory immune response of the gut after hemorrhage. DESIGN:Random assignment to either unmanipulated control after 7 days of SDD or conventional rat chow, or hemorrhagic shock group after the same time of conventio...

journal_title：Critical care medicine

authors： Kahlke V,Fändrich F,Brötzmann K,Zabel P,Schröder J

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVE:To investigate relationships between acute adrenergic stress, plasma catecholamine concentrations, and beta 2-adrenergic receptors. DESIGN:Prospective, descriptive study. SETTING:Emergency medical service at a university hospital. PATIENTS:Twenty-seven patients with out-of-hospital cardiac arrest (n = 11),...

journal_title：Critical care medicine

authors： Prengel AW,Lindner KH,Anhäupl T,Trunk E,Georgieff M,Lurie KG

更新日期：1997-04-01 00:00:00

abstract：:A high rate of death from septic shock persists despite general improvements in care. The relative failure of mechanistically based therapies in various clinical trials should also trigger a reconsideration of such mechanistic approaches. Despite reversion of shock by hydrocortisone, the similar death rate compared wi...

journal_title：Critical care medicine

authors： Lukaszewicz AC,Payen D

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:To examine the accuracy of brain multimodal monitoring-consisting of intracranial pressure, brain tissue PO2, and cerebral microdialysis--in detecting cerebral hypoperfusion in patients with severe traumatic brain injury. DESIGN:Prospective single-center study. PATIENTS:Patients with severe traumatic brain ...

journal_title：Critical care medicine

authors： Bouzat P,Marques-Vidal P,Zerlauth JB,Sala N,Suys T,Schoettker P,Bloch J,Daniel RT,Levivier M,Meuli R,Oddo M

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:To study the therapeutic effect of granulocyte colony-stimulating factor (G-CSF) on the mortality rate and host defense pattern in fulminant intra-abdominal sepsis. DESIGN:Prospective, randomized, controlled trial. SETTING:Research laboratory in a university hospital. SUBJECTS:Adult male Wistar rats. INTE...

journal_title：Critical care medicine

authors： Lundblad R,Nesland JM,Giercksky KE

更新日期：1996-05-01 00:00:00

abstract：OBJECTIVE:To review the anti-inflammatory and anti-apoptotic properties of drotrecogin alfa (activated) (recombinant human activated protein C), emphasizing its modulatory effects on endothelial nuclear factor-kappaB. We propose a broad anti-inflammatory effect of drotrecogin alfa (activated), acting on both endotheliu...

journal_title：Critical care medicine

authors： Joyce DE,Grinnell BW

更新日期：2002-05-01 00:00:00

abstract：OBJECTIVES:To evaluate the prevalence of cardiac injury and its association with mortality in hospitalized patients infected with avian influenza A (H7N9) virus. DESIGN:Retrospective cohort study. SETTING:A total of 133 hospitals in 17 provinces, autonomous regions, and municipalities of mainland China that admitted ...

journal_title：Critical care medicine

authors： Gao C,Wang Y,Gu X,Shen X,Zhou D,Zhou S,Huang JA,Cao B,Guo Q,Community-Acquired Pneumonia–China Network.

更新日期：2020-04-01 00:00:00

abstract：:The relationship between oxygen uptake (Vo2) and delivery (Do2) was examined in 64 patients immediately after cardiopulmonary bypass. In 44 patients with lactate levels below 2.5 mmol/L, Vo2 decreased proportionally when Do2 decreased below 300 ml/min X m2. At a Do2 over this level, Vo2 plateaued at 105 +/- 13 (SD) ml...

journal_title：Critical care medicine

authors： Komatsu T,Shibutani K,Okamoto K,Kumar V,Kubal K,Sanchala V,Lees DE

更新日期：1987-03-01 00:00:00

abstract：:During the treatment of 26 shocked patients, measurements were made of the central blood to peripheral skin temperature gradient. No significant correlation was found between this gradient and cardiac index (CI), or systemic vascular resistance (SVR) or its index (SVRI). There was no significant correlation between th...

journal_title：Critical care medicine

authors： Woods I,Wilkins RG,Edwards JD,Martin PD,Faragher EB

更新日期：1987-09-01 00:00:00

abstract：OBJECTIVE:To determine the maternal morbidity and mortality in patients with eclampsia admitted to an intensive care unit (ICU), and to establish the efficacy of the Acute Physiology and Chronic Health Evaluation (APACHE) II score, the organ system failure score as defined by Knaus, and the Glasgow Coma Scale (GCS) sco...

journal_title：Critical care medicine

authors： Bhagwanjee S,Paruk F,Moodley J,Muckart DJ

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:Peripheral perfusion in critically ill patients frequently is assessed by use of clinical signs. Recently, the pulse oximetry signal has been suggested to reflect changes in peripheral perfusion. A peripheral perfusion index based on analysis of the pulse oximetry signal has been implemented in monitoring sys...

journal_title：Critical care medicine

authors： Lima AP,Beelen P,Bakker J

更新日期：2002-06-01 00:00:00

abstract：:A survey of acute care/blood gas laboratories was conducted through the memberships of the Society of Critical Care Medicine ( SCCM ) and the National Association of Medical Directors of Respiratory Care ( NAMDRC ). Data were obtained from 227 laboratories and analyzed for operational characteristics, personnel, analy...

journal_title：Critical care medicine

authors： Hall JR,Shapiro BA

更新日期：1984-06-01 00:00:00

abstract：OBJECTIVE:To investigate the concentrations of reduced and total glutathione in relation to the muscle free amino acid pattern in critically ill patients and matched healthy controls. DESIGN:Prospective case control. SETTING:University hospital intensive care unit (ICU). PATIENTS:Eleven critically ill patients in th...

journal_title：Critical care medicine

authors： Hammarqvist F,Luo JL,Cotgreave IA,Andersson K,Wernerman J

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVES:To examine the effect of extracorporeal membrane oxygenation (ECMO) therapy on platelet function and number and to determine the in vivo survival of transfused platelets during ECMO. DESIGN:Prospective study of all neonates treated with ECMO during a 6-month period. SETTING:Neonatal intensive care unit in ...

journal_title：Critical care medicine

authors： Robinson TM,Kickler TS,Walker LK,Ness P,Bell W

更新日期：1993-07-01 00:00:00

abstract：OBJECTIVE:To compare three devices that measure core body temperature at the bedside in ICU patients. DESIGN:Prospective, consecutive sample. SETTING:Voluntary community teaching hospital. PATIENTS:Fifteen patients, 78 +/- 6 (SD) yrs of age, admitted to the medical ICU over a 5-month period who had pulmonary artery ...

journal_title：Critical care medicine

authors： Nierman DM

更新日期：1991-06-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy of the technique of selective decontamination of the digestive tract in preventing the development of secondary infection and its influence on morbidity and mortality rates in multiple trauma patients with chest injuries requiring intermittent positive-pressure ventilation. DESIGN:Pr...

journal_title：Critical care medicine

authors： Hammond JM,Potgieter PD,Saunders GL

更新日期：1994-01-01 00:00:00

abstract：:Measuring gas exchange in critically ill patients can provide valuable information on their nutritional status and energy expenditure. Several semiautomated machines are available for measuring oxygen consumption (VO2) and carbon dioxide production (VCO2). This study evaluated, under controlled laboratory conditions, ...

journal_title：Critical care medicine

authors： Eccles RC,Swinamer DL,Jones RL,King EG

更新日期：1986-09-01 00:00:00

abstract：OBJECTIVE:To define a biomarker panel to predict organ dysfunction, shock, and in-hospital mortality in emergency department (ED) patients with suspected sepsis. DESIGN:Prospective observational study. SETTING:EDs of ten academic medical centers. PATIENTS:There were 971 patients enrolled. INCLUSION CRITERIA:1) ED p...

journal_title：Critical care medicine

authors： Shapiro NI,Trzeciak S,Hollander JE,Birkhahn R,Otero R,Osborn TM,Moretti E,Nguyen HB,Gunnerson KJ,Milzman D,Gaieski DF,Goyal M,Cairns CB,Ngo L,Rivers EP

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVES:To explore the effects of dobutamine and norepinephrine on the global cardiovascular response and on the relationship between oxygen uptake (VO2) and oxygen delivery (DO2) during an acute reduction in blood flow associated with tamponade. DESIGN:Prospective, randomized, controlled acute intervention study. ...

journal_title：Critical care medicine

authors： Zhang H,Spapen H,Vincent JL

更新日期：1994-02-01 00:00:00

abstract：:Intravenous dobutamine was used in ten patients requiring aggressive therapy for massive pulmonary embolism with circulatory failure. Except in one patient who rapidly died, a 30-min dobutamine infusion (8.3 +/- 2.7 micrograms/kg . min) increased both cardiac index (from 1.7 +/- 0.4 to 2.3 +/- 0.6 L/min . m2, p less t...

journal_title：Critical care medicine

authors： Jardin F,Genevray B,Brun-Ney D,Margairaz A

更新日期：1985-12-01 00:00:00

abstract：:High-risk patients who survived general (noncardiac) surgery were observed to have cardiac index (CI) values averaging 4.5 L/min.m2, oxygen delivery (DO2) greater than 600 ml/min.m2, and oxygen consumption (VO2) 170 ml/min.m2 during the first 2 or three days postoperatively. Patients who subsequently died maintained r...

journal_title：Critical care medicine

authors： Shoemaker WC,Kram HB,Appel PL

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVES:To investigate the frequency, types, and implications of complications during intensive care in patients after status epilepticus has been successfully terminated. DESIGN:Retrospective study. SETTING:ICUs at a Swiss tertiary academic medical care center. PATIENTS:Data were collected from the digital patie...

journal_title：Critical care medicine

authors： Baumann SM,Semmlack S,De Marchis GM,Hunziker S,Rüegg S,Marsch S,Sutter R

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:To determine the pharmacokinetics of fentanyl when used as a long-term continuous infusion for sedation/analgesia in mechanically ventilated critically ill infants and children. DESIGN:Prospective, case series. SETTING:A university hospital pediatric intensive care unit (ICU). PATIENTS:Nineteen mechanicall...

journal_title：Critical care medicine

authors： Katz R,Kelly HW

更新日期：1993-07-01 00:00:00

abstract：OBJECTIVE:To assess the value of soluble triggering receptor expressed on myeloid cells-1 as a biomarker of infection in patients with neutropenic fever comparing with procalcitonin and C-reactive protein. DESIGN:Prospective, comparative, single-center study. SETTING:Hematology ward at a university hospital. SUBJECT...

journal_title：Critical care medicine

authors： Lin CH,Yao M,Hsu SC,Ho CC,Lin MT,Lin CA,Hu FC,Yu CJ,Tien HF

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:The renal effects of dopamine in critically ill patients remain controversial. Low-dose dobutamine has been reported to improve renal function. We compared the effects of various doses of dopamine and dobutamine on renal function in critically ill patients. DESIGN:Prospective, single-blind, randomized study....

journal_title：Critical care medicine

authors： Ichai C,Soubielle J,Carles M,Giunti C,Grimaud D

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVE:To investigate glycemic dynamics and its relation with mortality in critically ill patients. We searched for differences in complexity of the glycemic profile between survivors and nonsurvivors in patients admitted to a multidisciplinary intensive care unit. DESIGN:Prospective, observational study, convenien...

journal_title：Critical care medicine

authors： Lundelin K,Vigil L,Bua S,Gomez-Mestre I,Honrubia T,Varela M

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:To evaluate diagnostic and prognostic values of C-reactive protein (CRP) dosage in critically ill patients. DESIGN:Prospective, observational study. SETTING:Medical intensive care unit (ICU) in a university hospital. PATIENTS:A consecutive series of 74 patients admitted to the ICU. INTERVENTION:CRP measur...

journal_title：Critical care medicine

authors： Reny JL,Vuagnat A,Ract C,Benoit MO,Safar M,Fagon JY

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVE:To determine whether the absence or presence of clinical pharmacists in intensive care units (ICUs) results in differences in mortality rates, length of ICU stay, and ICU charges for Medicare patients with nosocomial-acquired infections, community-acquired infections, and sepsis. DESIGN, SETTING, AND PATIENT...

journal_title：Critical care medicine

authors： MacLaren R,Bond CA,Martin SJ,Fike D

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVES:Neurologic damage following cardiac arrest remains a major burden for modern resuscitation medicine. Cardiopulmonary resuscitation with extracorporeal circulatory support holds the potential to reduce morbidity and mortality. Furthermore, the endogenous gasotransmitter carbon monoxide attracts attention in r...

journal_title：Critical care medicine

authors： Wollborn J,Steiger C,Doostkam S,Schallner N,Schroeter N,Kari FA,Meinel L,Buerkle H,Schick MA,Goebel U

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVE:Despite concern over the appropriateness and quality of care provided in an intensive care unit (ICU) at the end of life, the number of Americans who receive ICU care at the end of life is unknown. We sought to describe the use of ICU care at the end of life in the United States using hospital discharge data ...

journal_title：Critical care medicine

authors： Angus DC,Barnato AE,Linde-Zwirble WT,Weissfeld LA,Watson RS,Rickert T,Rubenfeld GD,Robert Wood Johnson Foundation ICU End-Of-Life Peer Group.

更新日期：2004-03-01 00:00:00