Danger of using core/peripheral temperature gradient as a guide to therapy in shock.

abstract：OBJECTIVE:To evaluate the comparative efficacy of enteral cisapride, metoclopramide, erythromycin, and placebo for promoting gastric emptying in critically ill patients with intolerance to gastric enteral nutrition (EN). DESIGN:A randomized, crossover study. SETTING:Adult medical intensive care unit at a university-a...

journal_title：Critical care medicine

authors： MacLaren R,Kuhl DA,Gervasio JM,Brown RO,Dickerson RN,Livingston TN,Swift K,Headley S,Kudsk KA,Lima JJ

更新日期：2000-02-01 00:00:00

abstract：:To achieve synchronized differential pulmonary ventilation, an Ohio 560 ventilator was modified through separation of the outputs of the deep breath bellows and the tidal volume bellows and providing independent volume, flow rate, PEEP, oxygen-humidification, and alarm systems. The described ventilator modification is...

journal_title：Critical care medicine

authors： Popovich J Jr,Sanders OJ Jr,Vij D,Polanski JJ,Conway WA

更新日期：1981-06-01 00:00:00

abstract：BACKGROUND:Although survival is traditionally modeled using Cox proportional hazards modeling, this approach may be inappropriate in sepsis, in which the proportional hazards assumption does not hold. Newer, more flexible models, such as Gray's model, may be more appropriate. OBJECTIVES:To construct and compare Gray's...

journal_title：Critical care medicine

authors： Kasal J,Jovanovic Z,Clermont G,Weissfeld LA,Kaplan V,Watson RS,Angus DC

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVE:Increasing evidence, including publication of the Transfusion Requirements in Critical Care trial in 1999, supports a lower hemoglobin threshold for RBC transfusion in ICU patients. However, little is known regarding the influence of this evidence on clinical practice over time in a large population-based coh...

journal_title：Critical care medicine

authors： Murphy DJ,Needham DM,Netzer G,Zeger SL,Colantuoni E,Ness P,Pronovost PJ,Berenholtz SM

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVES:We reviewed randomized trials of adult ICU patients of interventions hypothesized to reduce delirium burden to determine whether interventions that are more effective at reducing delirium duration are associated with a reduction in short-term mortality. DATA SOURCES:We searched CINHAHL, EMBASE, MEDLINE, and...

journal_title：Critical care medicine

authors： Al-Qadheeb NS,Balk EM,Fraser GL,Skrobik Y,Riker RR,Kress JP,Whitehead S,Devlin JW

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:To assess the possible benefits of sympatholytics on uncontrolled hemorrhage in unanesthetized rats. DESIGN:A randomized laboratory study using rats to test the effects of sympatholytics on uncontrolled hemorrhage. SETTING:Research laboratory. SUBJECTS:Forty female Sprague-Dawley rats, randomly assigned in...

journal_title：Critical care medicine

authors： Rudé MJ,Soucy DM,Hagedorn F,Illner H,Shires GT

更新日期：1999-09-01 00:00:00

abstract：OBJECTIVES:Muscle weakness associated with critical illness can be due to the illness itself, immobilization associated with it, and/or to concomitant use of drugs that affect neuromuscular transmission. This study investigated the contribution of immobilization per se to the muscle dysfunction, as well as the associat...

journal_title：Critical care medicine

authors： Ibebunjo C,Martyn JA

更新日期：1999-02-01 00:00:00

abstract：OBJECTIVE:To evaluate the role of continuous lateral rotational therapy on the development of ventilator-associated pneumonia in patients requiring long-term mechanical ventilation. DESIGN:Prospective control study. SETTING:Chronic ventilator unit in tertiary care hospital. METHODS:Thirty-seven patients requiring lo...

journal_title：Critical care medicine

authors： Kirschenbaum L,Azzi E,Sfeir T,Tietjen P,Astiz M

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that a pretransport Pediatric Risk of Mortality (PRISM) score underestimates the requirement for both intensive care and interventions during pediatric interhospital transport. DESIGN:Prospective, descriptive study. SETTING:All children were treated in a regional hospital and then tra...

journal_title：Critical care medicine

authors： Orr RA,Venkataraman ST,Cinoman MI,Hogue BL,Singleton CA,McCloskey KA

更新日期：1994-01-01 00:00:00

abstract：:Intermittent Mandatory Ventilation (IMV) provides an alternative method of support to assisted and controlled mechanical ventilation in neonates with acute respiratory failure. Specific advantages include the use of only the level of mechanical support which is required on an individual basis. Because intrapleural pre...

journal_title：Critical care medicine

authors： Kirby RR

更新日期：1977-01-01 00:00:00

abstract：OBJECTIVE:To compare three devices that measure core body temperature at the bedside in ICU patients. DESIGN:Prospective, consecutive sample. SETTING:Voluntary community teaching hospital. PATIENTS:Fifteen patients, 78 +/- 6 (SD) yrs of age, admitted to the medical ICU over a 5-month period who had pulmonary artery ...

journal_title：Critical care medicine

authors： Nierman DM

更新日期：1991-06-01 00:00:00

abstract：:Arterial catheterization for blood gas analysis and direct monitoring of blood pressure in infants and children can be attended by a variety of complications, which limit its use to short periods of time. An improved technique, consisting of elimination of stopcocks, the use of a continuous flushing system adapted for...

journal_title：Critical care medicine

authors： Galvis AG,Donahoo JS,White JJ

更新日期：1976-05-01 00:00:00

abstract：OBJECTIVE:In the ICU, discussions between clinicians and surrogate decision makers are often accompanied by conflict about a patient's prognosis or care plan. Trust plays a role in limiting conflict, but little is known about the determinants of trust in the ICU. We sought to identify the dimensions of trust and clinic...

journal_title：Critical care medicine

authors： Hutchison PJ,McLaughlin K,Corbridge T,Michelson KN,Emanuel L,Sporn PH,Crowley-Matoka M

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the cardiopulmonary effects of the novel endothelin receptor antagonist tezosentan in endotoxin-induced lung injury in sheep and to assess the dose response to tezosentan and endothelin-1 in healthy sheep. DESIGN:Prospective, randomized, controlled experimental study. SETTING:University animal l...

journal_title：Critical care medicine

authors： Kuklin VN,Kirov MY,Evgenov OV,Sovershaev MA,Sjöberg J,Kirova SS,Bjertnaes LJ

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVE:The mortality of critically ill patients associated with intestinal ischemia/reperfusion remains very high, which results from multiorgan dysfunction or failure due to intestinal injury induced by intestinal ischemia/reperfusion. This study was carried out to investigate whether intestinal ischemia/reperfusio...

journal_title：Critical care medicine

authors： Zhou J,Huang WQ,Li C,Wu GY,Li YS,Wen SH,Lei WL,Liu KX

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:To determine whether low-dose dopamine administration reduces the incidence or severity of acute renal failure, need for dialysis, or mortality in patients with critical illness. DATA SOURCES AND STUDY SELECTION:We performed a MEDLINE search of literature published from 1966 to 2000 for studies addressing th...

journal_title：Critical care medicine

authors： Kellum JA,M Decker J

更新日期：2001-08-01 00:00:00

abstract：OBJECTIVE:Life-threatening conditions cause severe changes in the organization and conformation of macromolecules, creating urgent requirements for protein repair to ensure survival. As molecular chaperones, heat shock proteins (HSP) that have specialized functions in protein folding are now well established to restore...

journal_title：Critical care medicine

authors： Christians ES,Yan LJ,Benjamin IJ

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVES:Studies have shown contradicting results on the association of nursing workload and mortality. Most of these studies expressed workload as patients per nurse ratios; however, this does not take into account that some patients require more nursing time than others. Nursing time can be quantified by tools like...

journal_title：Critical care medicine

authors： Margadant C,Wortel S,Hoogendoorn M,Bosman R,Spijkstra JJ,Brinkman S,de Keizer N

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVES:To describe the variety of medications prescribed along with the doses administered and routes of administration, and to delineate the clarity of orders written and the accuracy of transcription of drugs used for sedation, anxiety, pain, and neuromuscular blockade in a surgical intensive care unit (ICU). DE...

journal_title：Critical care medicine

authors： Dasta JF,Fuhrman TM,McCandles C

更新日期：1994-06-01 00:00:00

abstract：OBJECTIVE:Prolonged stay in the intensive care unit (ICU) is associated with high mortality, morbidity, and costs. Identifying those patients who are most likely to benefit from an extended ICU stay would be helpful in guiding clinical decisions. We sought to describe the characteristics and outcomes for a heterogeneou...

journal_title：Critical care medicine

authors： Martin CM,Hill AD,Burns K,Chen LM

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVE:To comparatively evaluate cerebral metabolic rate of oxygen consumption and a modification of it, cerebral consumption of oxygen, in patients with acute brain injury with acute anemia. DESIGN:Prospective, observational study. SETTING:Neuroscience intensive care unit (ICU) of a university hospital. PATIENTS...

journal_title：Critical care medicine

authors： Cruz J,Jaggi JL,Hoffstad OJ

更新日期：1993-08-01 00:00:00

abstract：OBJECTIVE:To compare intraosseous with central venous blood samples for biochemical analyses and hemoglobin levels during cardiopulmonary resuscitation (CPR) and during cardiopulmonary resuscitation with infusion of sodium bicarbonate, epinephrine, and saline boluses through the intraosseous site. DESIGN:Prospective, ...

journal_title：Critical care medicine

authors： Johnson L,Kissoon N,Fiallos M,Abdelmoneim T,Murphy S

更新日期：1999-06-01 00:00:00

abstract：OBJECTIVE:To examine the relationship between aminoglycoside disposition kinetics and hemodynamic response to sepsis, as well as vital support therapy, in critically ill patients with sepsis. DESIGN:Cross-sectional study of critically ill patients with sepsis undergoing physiologic and aminoglycoside pharmacokinetic m...

journal_title：Critical care medicine

authors： Lugo G,Castañeda-Hernández G

更新日期：1997-05-01 00:00:00

abstract：OBJECTIVE:To examine the pulmonary and cardiac function of children who survived an episode of acute hypoxemic respiratory failure. DESIGN:Descriptive cohort analysis. SETTING:Pediatric clinical research center of a university hospital. PATIENTS:Utilizing the criteria of PaO2 < 75 torr (< 10 kPa) with an FIO2 of > 0...

journal_title：Critical care medicine

authors： Weiss I,Ushay HM,DeBruin W,O'Loughlin J,Rosner I,Notterman D

更新日期：1996-01-01 00:00:00

abstract：OBJECTIVE:To determine the effect that acute physiologic derangements have on outcome after subarachnoid hemorrhage (SAH) and to design a composite score summarizing these abnormalities. DESIGN:Prospective observational study. SETTING:Neuroscience intensive care unit in a tertiary care academic center. PATIENTS:Cons...

journal_title：Critical care medicine

authors： Claassen J,Vu A,Kreiter KT,Kowalski RG,Du EY,Ostapkovich N,Fitzsimmons BF,Connolly ES,Mayer SA

更新日期：2004-03-01 00:00:00

abstract：:We previously reported increased lipid peroxide and decreased alpha-tocopherol levels in the blood of critically ill septic patients. To clarify these results, we investigated lipid peroxidation in experimental septic rats and severely traumatized rats. In septic rats, both platelet count and plasma alpha-tocopherol d...

journal_title：Critical care medicine

authors： Takeda K,Shimada Y,Okada T,Amano M,Sakai T,Yoshiya I

更新日期：1986-08-01 00:00:00

abstract：OBJECTIVES:To measure energy expenditure in critically ill children and compare it with the energy expenditure predicted by recommended formulas, and relate the measured energy expenditure to nutritional and clinical indices. DESIGN:A prospective, clinical study. SETTING:Tertiary care pediatric intensive care unit in...

journal_title：Critical care medicine

authors： Briassoulis G,Venkataraman S,Thompson AE

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVE:To evaluate a new technique for pressure-volume curve tracing. DESIGN:Prospective experimental study. SETTING:Animal research laboratory. SUBJECTS:Six anesthetized rats. INTERVENTIONS:Two pressure-volume curves were obtained by means of the super-syringe method (gold standard) and the continuous positive ...

journal_title：Critical care medicine

authors： Albaiceta GM,Piacentini E,Villagrá A,Lopez-Aguilar J,Taboada F,Blanch L

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVES:In this study, we hypothesized that coronavirus disease 2019 patients exhibit sublingual microcirculatory alterations caused by inflammation, coagulopathy, and hypoxemia. DESIGN:Multicenter case-controlled study. SETTING:Two ICUs in The Netherlands and one in Switzerland. PATIENTS:Thirty-four critically i...

journal_title：Critical care medicine

authors： Favaron E,Ince C,Hilty MP,Ergin B,van der Zee P,Uz Z,Wendel Garcia PD,Hofmaenner DA,Acevedo CT,van Boven WJ,Akin S,Gommers D,Endeman H

更新日期：2021-01-07 00:00:00

abstract：:The determination of minute oxygen consumption (VO2) for metabolic studies on patients using either the Beckman Metabolic Cart (MMC) or the Respiratory Monitoring System (RMS) requires a stable fractional inspired oxygen concentration (FIO2). Measurement of VO2 on mechanically ventilated patients using the Bourns BEAR...

journal_title：Critical care medicine

authors： Browning JA,Linberg SE,Turney SZ,Chodoff P

更新日期：1982-02-01 00:00:00