Intermittent mandatory ventilation in the neonate.

abstract：OBJECTIVE:To measure patients' risk for acquiring antibiotic-resistant microorganisms associated with intensive care unit admission. DESIGN:Prospective, observational study. SETTING:Ten public hospitals including one university medical center. PATIENTS:Consecutive patients admitted to ten intensive care units. INTE...

journal_title：Critical care medicine

authors： Ho PL,Hong Kong intensive care unit antimicrobial resistance study (HK-ICARE) Group.

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVE:To examine the frequency of obtaining Institutional Review Board (IRB) approval and informed consent in critical care research. DATA SOURCES AND DATA EXTRACTION:One-year retrospective review of original critical care research in humans published in seven journals, including American Journal of Respiratory an...

journal_title：Critical care medicine

authors： Matot I,Pizov R,Sprung CL

更新日期：1998-09-01 00:00:00

abstract：OBJECTIVE:To determine whether the energy expenditure of mechanically ventilated multiple trauma patients correlates with the severity of injury and illness indices before important systemic infection has complicated the clinical course, and to compare the energy expenditure with the energy expenditure expected from th...

journal_title：Critical care medicine

authors： Brandi LS,Santini L,Bertolini R,Malacarne P,Casagli S,Baraglia AM

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVE:To assess the statistical association of the Acute Physiology and Chronic Health Evaluation (APACHE II) score with multiple intervention and outcome variables in surgical ICU patients. DESIGN:Continuous data collection on every patient admitted to the surgical ICU for a 21-month period. MATERIALS AND METHOD...

journal_title：Critical care medicine

authors： Rutledge R,Fakhry SM,Rutherford EJ,Muakkassa F,Baker CC,Koruda M,Meyer AA

更新日期：1991-08-01 00:00:00

abstract：OBJECTIVE:Life-threatening conditions cause severe changes in the organization and conformation of macromolecules, creating urgent requirements for protein repair to ensure survival. As molecular chaperones, heat shock proteins (HSP) that have specialized functions in protein folding are now well established to restore...

journal_title：Critical care medicine

authors： Christians ES,Yan LJ,Benjamin IJ

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND AND METHODS:We aimed to characterize the effects of an endotoxin insult (Escherichia coli 0127:B8) on the relationships between pulmonary vascular pressure and flow in intact dogs. To achieve this goal, multipoint plots of total pressure gradient, arterial pressure gradient, and venous pressure gradient vs. ...

journal_title：Critical care medicine

authors： D'Orio V,Fatemi M,Marnette JM,Mendes P,Saad G,Martinez C,Marcelle R

更新日期：1992-07-01 00:00:00

abstract：OBJECTIVE:Vasopressin is a possible stimulus for both adrenocorticotropin (ACTH) and endothelin-1 release. The aim of this study was to compare plasma concentrations of ACTH, cortisol, and endothelin-1 after epinephrine or vasopressin administration in an experimental animal model of cardiopulmonary resuscitation (CPR)...

journal_title：Critical care medicine

authors： Kornberger E,Prengel AW,Krismer A,Schwarz B,Wenzel V,Lindner KH,Mair P

更新日期：2000-10-01 00:00:00

abstract：:The current investigation describes the morphological and pathophysiological effects of stroma-free hemoglobin solution (SFH) on the liver and kidney. One h after a 75% blood volume exchange in animals receiving 7% SFH, hepatic morphology was normal. Animals whose blood was similarly exchanged with 7% albumin demonstr...

journal_title：Critical care medicine

authors： Friedman HI,DeVenuto F

更新日期：1982-04-01 00:00:00

abstract：:Ischemia of the intestines damages the permeability of the intestinal wall, allowing lipopolysaccharide (LPS) (endotoxin) to leak from the gut lumen into the blood circulation, causing shock and death. We measured LPS levels associated with corticosteroid treatment vs. no treatment in cats whose superior mesenteric ar...

journal_title：Critical care medicine

authors： Gaffin SL,Gathiram P,Wells MT,Brock-Utne JG

更新日期：1986-10-01 00:00:00

abstract：OBJECTIVES:There is limited evidence supporting the widespread use of α2 agonists (clonidine and dexmedetomidine) in pediatric critical care sedation. This study sought to test the association between the use of α2 agonists and enhanced sedation. DESIGN:A retrospective observational cohort study was conducted. Noninfe...

journal_title：Critical care medicine

authors： Hayden JC,Doherty DR,Dawkins I,Leacy FP,Healy M,Breatnach CV,Cousins G,Gallagher PJ

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:To investigate glycemic dynamics and its relation with mortality in critically ill patients. We searched for differences in complexity of the glycemic profile between survivors and nonsurvivors in patients admitted to a multidisciplinary intensive care unit. DESIGN:Prospective, observational study, convenien...

journal_title：Critical care medicine

authors： Lundelin K,Vigil L,Bua S,Gomez-Mestre I,Honrubia T,Varela M

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:To assess the prevalence of acute kidney injury in patients with subarachnoid hemorrhage patients. DESIGN:Retrospective analysis of all subarachnoid hemorrhage admissions. SETTINGS:Neurocritical care unit. PATIENTS:All patients with a diagnosis of subarachnoid hemorrhage between 2009 and 2014. INTERVENTIO...

journal_title：Critical care medicine

authors： Sadan O,Singbartl K,Kandiah PA,Martin KS,Samuels OB

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVES:To determine whether high rates of ineffective triggering within the first 24 hrs of mechanical ventilation (MV) are associated with longer MV duration and shorter ventilator-free survival (VFS). DESIGN:Prospective cohort study. SETTING:Medical intensive care unit (ICU) at an academic medical center. PATI...

journal_title：Critical care medicine

authors： de Wit M,Miller KB,Green DA,Ostman HE,Gennings C,Epstein SK

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:The pathogenesis of acute gastric stress ulceration in the seriously ill is uncertain, and any role of Helicobacter pylori infection is unknown. We aimed to assess the relationship between H. pylori serological status and stress ulceration in seriously ill patients, as well as H. pylori serological status in ...

journal_title：Critical care medicine

authors： Robertson MS,Cade JF,Clancy RL

更新日期：1999-07-01 00:00:00

abstract：OBJECTIVE:To investigate if prone position delays the progression of experimental ventilator-induced lung injury, possibly due to a more homogeneous distribution of strain within lung parenchyma. DESIGN:Prospective, randomized, controlled trial. SETTING:Animal laboratory of a university hospital. SUBJECTS:Thirty-fiv...

journal_title：Critical care medicine

authors： Valenza F,Guglielmi M,Maffioletti M,Tedesco C,Maccagni P,Fossali T,Aletti G,Porro GA,Irace M,Carlesso E,Carboni N,Lazzerini M,Gattinoni L

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVES:Our primary goal was to evaluate the impact on in-hospital mortality rate of adequate empirical antibiotic therapy, after controlling for confounding variables, in a cohort of patients admitted to the intensive care unit (ICU) with sepsis. The impact of adequate empirical antibiotic therapy on early (<3 days...

journal_title：Critical care medicine

authors： Garnacho-Montero J,Garcia-Garmendia JL,Barrero-Almodovar A,Jimenez-Jimenez FJ,Perez-Paredes C,Ortiz-Leyba C

更新日期：2003-12-01 00:00:00

abstract：OBJECTIVE:To determine whether partial liquid ventilation (PLV) affects the risk of nosocomial pneumonia. STUDY DESIGN:To assess in vitro bacterial adhesion and viability after liquid perfluorocarbon exposure and to assess bacterial recovery after partial liquid ventilation in vivo in rabbits. SETTING:University anim...

journal_title：Critical care medicine

authors： Sajan I,Scannapieco FA,Fuhrman BP,Steinhorn DM

更新日期：1999-12-01 00:00:00

abstract：:Twenty preterm infants in respiratory distress, each with an umbilical catheter in place, were studied during their first 24 h of hospitalization, to determine the effects of continuous transcutaneous oxygen (PtcO2) monitoring on the frequency of arterial blood gas (ABG) determinations and on the incidence of hypoxia ...

journal_title：Critical care medicine

authors： Kilbride HW,Merenstein GB

更新日期：1984-02-01 00:00:00

abstract：:To determine the influence of arachidonic acid metabolites on acute lung injury induced by glass bead embolism, two groups of animals were studied before and after the pulmonary artery pressure was doubled by glass bead embolism. One group represented an untreated time control (n = 6) while the second group (n = 6) wa...

journal_title：Critical care medicine

authors： Calvin JE,Dervin G

更新日期：1988-09-01 00:00:00

abstract：OBJECTIVE:To determine whether neutrophil depletion could eradicate intestinal bacterial translocation in bum-injured rats. DESIGN:Prospective, randomized, controlled study. SETTING:University research laboratory. SUBJECTS:Adult male Sprague-Dawley rats. INTERVENTIONS:The rats were intravenously administered a rabb...

journal_title：Critical care medicine

authors： Fazal N,Shamim M,Khan SS,Gamelli RL,Sayeed MM

更新日期：2000-05-01 00:00:00

abstract：OBJECTIVES:To investigate attitudes and practices regarding oxygen therapy in intensive care units (ICUs) and to devise quantitative descriptive indices. SETTING:Canadian university-affiliated adult ICUs. PARTICIPANTS:Fifty-two medical directors of ICUs in 48 institutions. INTERVENTION:Structured postal questionnair...

journal_title：Critical care medicine

authors： Mao C,Wong DT,Slutsky AS,Kavanagh BP

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVE:Persistent pulmonary hypertension of the newborn is characterized by the presence of intense vasoconstriction and vascular remodeling. Protein tyrosine phosphorylation has been recognized as a critical regulatory element in signal transduction, because it is dynamically regulated by the opposing actions of pr...

journal_title：Critical care medicine

authors： Berkenbosch JW,Baribeau J,Ferretti E,Perreault T

更新日期：2001-06-01 00:00:00

abstract：:An 8-yr-old child suffered traumatic bilateral pneumothoraces and a ruptured right main bronchus. Surgical repair of the bronchus was postponed for 18 h after a definite diagnosis was established due to severe hypoxemia and hypercarbia. Only left endobronchial high-frequency ventilation with muscle relaxation correcte...

journal_title：Critical care medicine

authors： Pizov R,Shir Y,Eimerl D,Uretzky G,Milgalter E,Cotev S

更新日期：1987-12-01 00:00:00

abstract：OBJECTIVES:To describe the unique perspective of pediatric intensivists caring for critically ill adults during the coronavirus disease 2019 pandemic. DESIGN:Observational study. SETTING:Academic medical center in New York City. PATIENTS:Coronavirus disease 2019 positive adults requiring admission to an ICU. INTERV...

journal_title：Critical care medicine

authors： Joyce CL,Howell JD,Toal M,Wasserman E,Finkelstein RA,Traube C,Killinger JS,Joashi U,Greenwald BM,Nellis ME

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:Inotropic and vasopressor drugs are routinely used in critically ill patients to maintain adequate blood pressure and cardiac output in patients with cardiogenic shock although potentially at the expense of increasing myocardial oxygen demand. Pacing optimization has been demonstrated as effective in reducing...

journal_title：Critical care medicine

authors： Tavazzi G,Kontogeorgis A,Bergsland NP,Price S

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:To evaluate the performance at admission to the pediatric intensive care unit (PICU) of five severity scores, two general (the Pediatric Risk of Mortality [PRISM] II and III scores) and three specific for meningococcal septic shock (Leclerc, Glasgow Meningococcal Septicemia Prognostic Score [GMSPS], and Gedde...

journal_title：Critical care medicine

authors： Castellanos-Ortega A,Delgado-Rodríguez M

更新日期：2000-08-01 00:00:00

abstract：OBJECTIVES:Inhaled nitric oxide is being utilized as a selective pulmonary vasodilator in the treatment of persistent pulmonary hypertension of the newborn. However, the effects of inhaled nitric oxide on cerebral hemodynamics and distribution of left ventricular output in newborn subjects have not been studied. This s...

journal_title：Critical care medicine

authors： Rosenberg AA,Kinsella JP,Abman SH

更新日期：1995-08-01 00:00:00

abstract：:Simple insertion of a nasogastric (NG) tube was successful in only 52 of 100 anesthetized intubated patients. After the larynx was manually pulled forward, the NG tube was successfully inserted in 33 patients. In the remaining 15 patients, the NG tube was inserted only with the aid of a finger or a laryngoscope used w...

journal_title：Critical care medicine

authors： Perel A,Ya'ari Y,Pizov R

更新日期：1985-03-01 00:00:00

abstract：:In order to examine the prognostic value of pulmonary arterial hypertension (PAH) in patients with moderate and severe acute respiratory failure (ARF), 225 patients with ARF who had been treated with mechanical ventilation and admitted to our ICU during a 3-yr period (January, 1983 to January, 1986) were prospectively...

journal_title：Critical care medicine

authors： Villar J,Blazquez MA,Lubillo S,Quintana J,Manzano JL

更新日期：1989-06-01 00:00:00

abstract：OBJECTIVE:To determine if inhibition of nitric oxide synthase with NG-nitro-L-arginine-methyl-ester (L-NAME) potentiates endotoxin-induced cardiopulmonary dysfunction and release of cyclooxygenase products in a porcine model of endotoxemia. DESIGN:Prospective, multiple group, controlled experimental study. SETTING:Ph...

journal_title：Critical care medicine

authors： Hellyer PW,Johnson LW,Olson NC

更新日期：1997-06-01 00:00:00