Effect of corticosteroid prophylaxis on lipopolysaccharide levels associated with intestinal ischemia in cats.

abstract：OBJECTIVE:The receptor for advanced glycation end products mediates a variety of inflammatory responses. Soluble receptor for advanced glycation end products has been suggested to function as a decoy abrogating cellular activation. High-mobility group box 1 is a high-affinity binding ligand for the receptor for advance...

journal_title：Critical care medicine

authors： van Zoelen MA,Achouiti A,Schmidt AM,Yang H,Florquin S,Tracey KJ,van der Poll T

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVES:Peripherally inserted central catheters are increasingly used in ICU as an alternative to centrally inserted central catheters for IV infusion. However, their reliability for hemodynamic measurements with transpulmonary thermodilution is currently unknown. We investigated the agreement between transpulmonary...

journal_title：Critical care medicine

authors： D'Arrigo S,Sandroni C,Cacciola S,Dell'Anna AM,Pittiruti M,Annetta MG,Colosimo C,Antonelli M

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:To describe a postpartum patient who presented with fulminant hepatic failure and hepatic coma as a result of unrecognized peripartum cardiomyopathy. DESIGN:Case report. SETTING:Medical intensive care unit of a tertiary care academic medical center. PATIENT:A 35-yr-old woman 5 wks postpartum from an uneven...

journal_title：Critical care medicine

authors： Fussell KM,Awad JA,Ware LB

更新日期：2005-04-01 00:00:00

abstract：OBJECTIVE:To describe the experience of pediatric intensive care hospitalization from the perspective of a parents of children with severe, antecedent disability. DESIGN:Qualitative analysis of data obtained through semistructured interviews. SETTING:Pediatric intensive care unit (PICU) in a children's hospital. SUB...

journal_title：Critical care medicine

authors： Graham RJ,Pemstein DM,Curley MA

更新日期：2009-06-01 00:00:00

abstract：:Sepsis and resulting multiple system organ failure are the leading causes of mortality in intensive care units. Although it is generally appreciated that rampant, deregulated inflammatory pathways play a major role in sepsis, a comprehensive understanding based on the integrated response of multiple signal transductio...

journal_title：Critical care medicine

authors： Nguyen A,Yaffe MB

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:To test whether spectral indices derived from the electroencephalogram (EEG), and especially the bispectral index (BIS), can be used as measures of neurologic status in unsedated, critically ill patients. DESIGN:Prospective, observational study. SETTING:Medical intensive care unit (ICU) of a university-affi...

journal_title：Critical care medicine

authors： Gilbert TT,Wagner MR,Halukurike V,Paz HL,Garland A

更新日期：2001-10-01 00:00:00

abstract：OBJECTIVES:To understand when the use of high-frequency ventilation would be advantageous, we formulated the problem of achieving adequate alveolar ventilation at minimal pressure cost by dividing it into two simpler problems: a) the pressure cost per unit of convective oscillatory flow; and b) the convective flow cost...

journal_title：Critical care medicine

authors： Venegas JG,Fredberg JJ

更新日期：1994-09-01 00:00:00

abstract：OBJECTIVES:Existing handheld glucose meters are glucose oxidase (GO)-based. Oxygen side reactions can introduce oxygen dependency, increase potential error, and limit clinical use. Our primary objectives were to: a) introduce a new glucose dehydrogenase (GD)-based electrochemical biosensor for point-of-care testing; b)...

journal_title：Critical care medicine

authors： Kost GJ,Vu HT,Lee JH,Bourgeois P,Kiechle FL,Martin C,Miller SS,Okorodudu AO,Podczasy JJ,Webster R,Whitlow KJ

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND AND METHODS:Twelve adult male albino rabbits were assigned alternately to normotensive and hypotensive groups to assess the effect of hypovolemic shock on spontaneous correction of dilutional coagulopathy. All animals underwent dilutional exchange transfusion with 200 mL of rabbit RBCs and 5% human albumin. ...

journal_title：Critical care medicine

authors： Hewson JR,Prodger D,Roberts RS,Davis C,Fuller HD,Gregor P,Thomas EJ,Shragge BW,Russett J,Neame PB

更新日期：1991-02-01 00:00:00

abstract：OBJECTIVE:To evaluate the use of enriched thioglycolate as a transport medium of protected specimen brush samples, in particular its value in direct examination of respiratory specimens and in guiding initial antibiotic prescription. DESIGN:Prospective, randomized, pilot study. SETTING:Medical-surgical teaching inten...

journal_title：Critical care medicine

authors： Rello J,Mariscal D,Gallego M,Valles J

更新日期：2002-02-01 00:00:00

abstract：OBJECTIVE:Antimicrobial effects of nitric oxide (NO) have been demonstrated in vitro against a variety of infectious pathogens, yet in vivo evidence of a potential therapeutic role for exogenous NO as an antimicrobial agent is limited. Thus, we assessed the effects of inhaled NO on pulmonary infection, leukocyte infilt...

journal_title：Critical care medicine

authors： Webert KE,Vanderzwan J,Duggan M,Scott JA,McCormack DG,Lewis JF,Mehta S

更新日期：2000-07-01 00:00:00

abstract：OBJECTIVE:To assess the effects of dopexamine on splanchnic blood flow and splanchnic oxygen uptake in septic patients. DESIGN:A prospective, controlled trial. SETTING:A ten-bed intensive care unit (ICU) in a university hospital. PATIENTS:Twelve patients with severe sepsis (according to the criteria of the 1992 Amer...

journal_title：Critical care medicine

authors： Meier-Hellmann A,Bredle DL,Specht M,Hannemann L,Reinhart K

更新日期：1999-10-01 00:00:00

abstract：OBJECTIVE:Inotropic and vasopressor drugs are routinely used in critically ill patients to maintain adequate blood pressure and cardiac output in patients with cardiogenic shock although potentially at the expense of increasing myocardial oxygen demand. Pacing optimization has been demonstrated as effective in reducing...

journal_title：Critical care medicine

authors： Tavazzi G,Kontogeorgis A,Bergsland NP,Price S

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:To assess clinician perceptions of a machine learning-based early warning system to predict severe sepsis and septic shock (Early Warning System 2.0). DESIGN:Prospective observational study. SETTING:Tertiary teaching hospital in Philadelphia, PA. PATIENTS:Non-ICU admissions November-December 2016. INTERVE...

journal_title：Critical care medicine

authors： Ginestra JC,Giannini HM,Schweickert WD,Meadows L,Lynch MJ,Pavan K,Chivers CJ,Draugelis M,Donnelly PJ,Fuchs BD,Umscheid CA

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVES:A growing number of patients survive sepsis hospitalizations each year and are at high risk for readmission. However, little is known about temporal trends in hospital-based acute care (emergency department treat-and-release visits and hospital readmission) after sepsis. Our primary objective was to measure ...

journal_title：Critical care medicine

authors： Meyer N,Harhay MO,Small DS,Prescott HC,Bowles KH,Gaieski DF,Mikkelsen ME

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVES:To describe the variety of medications prescribed along with the doses administered and routes of administration, and to delineate the clarity of orders written and the accuracy of transcription of drugs used for sedation, anxiety, pain, and neuromuscular blockade in a surgical intensive care unit (ICU). DE...

journal_title：Critical care medicine

authors： Dasta JF,Fuhrman TM,McCandles C

更新日期：1994-06-01 00:00:00

abstract：OBJECTIVE:To determine the effect of two doses of prostaglandin E1 (PGE1, alprostadil) combined with unfractionated heparin on the hemofilter life-span and the coagulation profile during continuous venovenous hemofiltration. DESIGN:Prospective, randomized, controlled trial. SETTING:Intensive care unit at a university...

journal_title：Critical care medicine

authors： Kozek-Langenecker SA,Kettner SC,Oismueller C,Gonano C,Speiser W,Zimpfer M

更新日期：1998-07-01 00:00:00

abstract：PURPOSE:To describe the dark side of pediatric intensive care fellowship training and offer educational approaches for understanding feelings of fallibility, anger, frustration, and loss. DATA SOURCES:Listening and observing fellows in the courses of their pediatric intensive care training and later careers. STUDY SE...

journal_title：Critical care medicine

authors： Jellinek MS,Todres ID,Catlin EA,Cassem EH,Salzman A

更新日期：1993-05-01 00:00:00

abstract：OBJECTIVES:Recently, the definition of sepsis has changed from a physiologic derangement (Sepsis-1 and -2) to organ dysfunction (Sepsis-3) based. We sought to determine the concordance between the different sepsis phenotypes and how that affected mortality. DESIGN:Retrospective, multicenter study. SETTING:Three acade...

journal_title：Critical care medicine

authors： Engoren M,Seelhammer T,Freundlich RE,Maile MD,Sigakis MJG,Schwann TA

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVES:To determine whether relative hyperglycemia was associated with in-hospital mortality in critically ill patients independent of other prognostic variables and whether this association is affected by background glycemia. DESIGN:Prospective observational study. SETTING:Mixed medical-surgical ICU in a metropo...

journal_title：Critical care medicine

authors： Lee TF,Drake SM,Roberts GW,Bersten A,Stranks SN,Heilbronn LK,Mangoni AA,Burt MG

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVE:To examine the relationship between treatment-related variables for Candida bloodstream infection and hospital mortality. DESIGN:Retrospective cohort analysis. SETTING:Thousand two hundred-bed academic medical center. PATIENTS:A total of 245 consecutive patients with Candida bloodstream infections who rece...

journal_title：Critical care medicine

authors： Labelle AJ,Micek ST,Roubinian N,Kollef MH

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVE:To determine the incidence and risk factors of chronic critical illness after severe blunt trauma. DESIGN:Prospective observational cohort study (NCT01810328). SETTING:Two level-one trauma centers in the United States. PATIENTS:One hundred thirty-five adult blunt trauma patients with hemorrhagic shock who ...

journal_title：Critical care medicine

authors： Mira JC,Cuschieri J,Ozrazgat-Baslanti T,Wang Z,Ghita GL,Loftus TJ,Stortz JA,Raymond SL,Lanz JD,Hennessy LV,Brumback B,Efron PA,Baker HV,Moore FA,Maier RV,Moldawer LL,Brakenridge SC

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVES:Secretoneurin is associated with cardiomyocyte Ca handling and improves risk prediction in patients with acute myocardial dysfunction. Whether secretoneurin improves risk assessment on top of established cardiac biomarkers and European System for Cardiac Operative Risk Evaluation II in patients undergoing ca...

journal_title：Critical care medicine

authors： Brynildsen J,Petäjä L,Myhre PL,Lyngbakken MN,Nygård S,Stridsberg M,Christensen G,Ottesen AH,Pettilä V,Omland T,Røsjø H

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVES:a) To investigate whether the patient work of breathing needed to trigger inspiration is affected by the type of ventilator delivering pressure-support ventilation for mechanically ventilated pediatric patients. b) To determine whether changes in oxygen consumption (VO2) trend with changes in work of breathi...

journal_title：Critical care medicine

authors： el-Khatib MF,Chatburn RL,Potts DL,Blumer JL,Smith PG

更新日期：1994-12-01 00:00:00

abstract：OBJECTIVES:Although studies have indicated that adrenal insufficiency occurs after severe trauma and hemorrhagic shock, it remains controversial whether adrenal function is depressed during the late stage of polymicrobial sepsis. DESIGN:Prospective, controlled animal study. SETTING:A university research laboratory. ...

journal_title：Critical care medicine

authors： Koo DJ,Jackman D,Chaudry IH,Wang P

更新日期：2001-03-01 00:00:00

abstract：:Because determining cardiac output is difficult in premature infants, little is known about the hemodynamic effects of PEEP in this age group. We used pulsed-wave Doppler echocardiography to assess the hemodynamic effects of PEEP increments in ten premature infants with respiratory distress syndrome. At a PEEP of 4 cm...

journal_title：Critical care medicine

authors： Hausdorf G,Hellwege HH

更新日期：1987-07-01 00:00:00

abstract：OBJECTIVES:To compare the plasma volume (PV) expanding effect of a fast infusion rate with that of a slow infusion rate of a fixed volume of 5% albumin, of the synthetic colloids, 6% hydroxyethyl starch 130/0.4 and 4% gelatin, and of 0.9% NaCl in a rat sepsis model and to compare the plasma-expanding effect among these...

journal_title：Critical care medicine

authors： Bark BP,Persson J,Grände PO

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVES:The association between tobacco smoke exposure and critical illness is not well studied, largely because obtaining an accurate smoking history from critically ill patients is difficult. Biomarkers can provide quantitative data on active and secondhand cigarette smoke exposure. We sought to compare cigarette ...

journal_title：Critical care medicine

authors： Hsieh SJ,Ware LB,Eisner MD,Yu L,Jacob P 3rd,Havel C,Goniewicz ML,Matthay MA,Benowitz NL,Calfee CS

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVES:Mild decrease in core temperature (therapeutic hypothermia) provides lasting neuroprotection following cardiac arrest or cerebral ischemia. However, current methods for producing therapeutic hypothermia trigger a cold-defense response that must be countered by sedatives, muscle paralytics, and mechanical ven...

journal_title：Critical care medicine

authors： Feketa VV,Zhang Y,Cao Z,Balasubramanian A,Flores CM,Player MR,Marrelli SP

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVES:To define the hemodynamic and gastric intramucosal PCO2 (PiCO2) changes during the first 48 hrs after burn trauma and to analyze their relationship with outcome. DESIGN:Prospective, observational study in a cohort of consecutively admitted critically ill burn patients. SETTING:Intensive care burn unit in a...

journal_title：Critical care medicine

authors： Lorente JA,Ezpeleta A,Esteban A,Gordo F,de la Cal MA,Díaz C,Arévalo JM,Tejedor C,Pascual T

更新日期：2000-06-01 00:00:00