Importance of the infusion rate for the plasma expanding effect of 5% albumin, 6% HES 130/0.4, 4% gelatin, and 0.9% NaCl in the septic rat.

abstract：OBJECTIVES:Targeted temperature management has been shown to improve survival with good neurological outcome in patients after out-of-hospital cardiac arrest. The optimal approach to inducing and maintaining targeted temperature management, however, remains uncertain. The objective of this study was to evaluate these p...

journal_title：Critical care medicine

authors： Lin S,Scales DC,Dorian P,Kiss A,Common MR,Brooks SC,Goodman SG,Salciccioli JD,Morrison LJ

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:To assess clinician perceptions of a machine learning-based early warning system to predict severe sepsis and septic shock (Early Warning System 2.0). DESIGN:Prospective observational study. SETTING:Tertiary teaching hospital in Philadelphia, PA. PATIENTS:Non-ICU admissions November-December 2016. INTERVE...

journal_title：Critical care medicine

authors： Ginestra JC,Giannini HM,Schweickert WD,Meadows L,Lynch MJ,Pavan K,Chivers CJ,Draugelis M,Donnelly PJ,Fuchs BD,Umscheid CA

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVES:Sepsis-associated changes of the arachidonic acid metabolism and the utility of arachidonic acid metabolites for the diagnosis of sepsis have been poorly investigated so far. Therefore, the primary objective of our study was to screen for differentially regulated arachidonic acid metabolites in septic patien...

journal_title：Critical care medicine

authors： Bruegel M,Ludwig U,Kleinhempel A,Petros S,Kortz L,Ceglarek U,Holdt LM,Thiery J,Fiedler GM

更新日期：2012-05-01 00:00:00

abstract：:Patients (n = 158) who had been respirator-treated and who could remember the treatment were retrospectively (after greater than 2 months) interviewed about their experiences. Of all patients, 47% had felt anxiety and/or fear during the treatment. These feelings were intimately related to the experience of agony/panic...

journal_title：Critical care medicine

authors： Bergbom-Engberg I,Haljamäe H

更新日期：1989-10-01 00:00:00

abstract：OBJECTIVE:Use of antibiotics in critically ill patients may increase the risk of invasive Candida infection. The objective of this study was to determine whether increased exposure to antibiotics is associated with increased prevalence of invasive Candida infection. DESIGN:Substudy using data from a randomized control...

journal_title：Critical care medicine

authors： Jensen JU,Hein L,Lundgren B,Bestle MH,Mohr T,Andersen MH,Løken J,Tousi H,Søe-Jensen P,Lauritsen AØ,Strange D,Petersen JA,Thormar K,Larsen KM,Drenck NE,Helweg-Larsen J,Johansen ME,Reinholdt K,Møller JK,Olesen B,Are

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVES:To investigate family perceptions of having a nurse participating in family conferences and to assess the psychologic well being of the same families after ICU discharge. DESIGN:Mixed-method design with a qualitative study embedded in a single-center randomized study. SETTING:Twelve-bed medical-surgical IC...

journal_title：Critical care medicine

authors： Garrouste-Orgeas M,Max A,Lerin T,Grégoire C,Ruckly S,Kloeckner M,Brochon S,Pichot E,Simons C,El-Mhadri M,Bruel C,Philippart F,Fournier J,Tiercelet K,Timsit JF,Misset B

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVE:To quantify the therapeutic efficacy of loop diuretics in acute renal failure using Bayesian evidence synthesis, because despite widespread use, the role of diuretics is controversial. DATA SOURCE:Randomized controlled trials or nonrandomized studies, 1966 to January 2007, identified from MEDLINE and EMBASE ...

journal_title：Critical care medicine

authors： Sampath S,Moran JL,Graham PL,Rockliff S,Bersten AD,Abrams KR

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:To study the impact of diabetes mellitus on the relationship between glycemia and mortality in critically ill patients. DESIGN:Retrospective observational study. SETTING:Intensive care units of two university hospitals. PATIENTS:Cohort of 4946 critically ill patients including 728 patients with diabetes me...

journal_title：Critical care medicine

authors： Egi M,Bellomo R,Stachowski E,French CJ,Hart GK,Hegarty C,Bailey M

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVE:To determine the maternal morbidity and mortality in patients with eclampsia admitted to an intensive care unit (ICU), and to establish the efficacy of the Acute Physiology and Chronic Health Evaluation (APACHE) II score, the organ system failure score as defined by Knaus, and the Glasgow Coma Scale (GCS) sco...

journal_title：Critical care medicine

authors： Bhagwanjee S,Paruk F,Moodley J,Muckart DJ

更新日期：2000-01-01 00:00:00

abstract：:Intermittent Mandatory Ventilation (IMV) provides an alternative method of support to assisted and controlled mechanical ventilation in neonates with acute respiratory failure. Specific advantages include the use of only the level of mechanical support which is required on an individual basis. Because intrapleural pre...

journal_title：Critical care medicine

authors： Kirby RR

更新日期：1977-01-01 00:00:00

abstract：OBJECTIVE:To describe three female patients of one family with different phenotypes of the same mutation of the ornithine transcarbamylase gene. X-linked inherited ornithine transcarbamylase deficiency is the most frequent urea cycle disorder. Many of the hemizygous males die during the neonatal period. Women, who are ...

journal_title：Critical care medicine

authors： Legras A,Labarthe F,Maillot F,Garrigue MA,Kouatchet A,Ogier de Baulny H

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVES:To evaluate the association between length of ICU stay and 1-year mortality for elderly patients who survived to hospital discharge in the United States. DESIGN:Retrospective cohort study of a random sample of Medicare beneficiaries who survived to hospital discharge, with 1- and 3-year follow-up, stratifie...

journal_title：Critical care medicine

authors： Moitra VK,Guerra C,Linde-Zwirble WT,Wunsch H

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:To investigate the interrelationship between cardiac surgery, age, circulating concentrations of the vitamin D hormone 1,25-dihydroxyvitamin D, and clinical outcome. DESIGN:Prospective, monocentric, two-arm parallel study. SETTING:Tertiary Heart and Diabetes Center in the Federal State of North Rhine-Westph...

journal_title：Critical care medicine

authors： Börgermann J,Lazouski K,Kuhn J,Dreier J,Schmidt M,Gilis-Januszewski T,Knabbe C,Gummert JF,Zittermann A

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:Our first objective was to determine a blood lactate threshold predictive of survival in human immunodeficiency virus patients experiencing lactic acidosis related to nucleoside analogs, and second, to test l-carnitine for the treatment of patients exceeding that threshold. DESIGN:a) Retrospective study usin...

journal_title：Critical care medicine

authors： Claessens YE,Cariou A,Monchi M,Soufir L,Azoulay E,Rouges P,Goldgran-Toledano D,Branche F,Dhainaut JF

更新日期：2003-04-01 00:00:00

abstract：:Bacterial translocation and ileal and cecal injury have been shown to occur 24 h after limited periods of hemorrhagic shock. The present studies were performed to determine the temporal sequence of mucosal injury, permeability, and bacterial translocation after hemorrhagic shock. The results indicated that bacterial t...

journal_title：Critical care medicine

authors： Deitch EA,Morrison J,Berg R,Specian RD

更新日期：1990-05-01 00:00:00

abstract：OBJECTIVES:This report examines the frequency, type, and prognostic factors of medical (nonneurologic) complications after subarachnoid hemorrhage in a large, prospective study. The influences of contemporary neurosurgical, neurological, and critical care practice on mortality and morbidity rates after aneurysmal subar...

journal_title：Critical care medicine

authors： Solenski NJ,Haley EC Jr,Kassell NF,Kongable G,Germanson T,Truskowski L,Torner JC

更新日期：1995-06-01 00:00:00

abstract：OBJECTIVE:Acute aneurysmal subarachnoid hemorrhage (SAH) is a complex multifaceted disorder that plays out over days to weeks. Many patients with SAH are seriously ill and require a prolonged intensive care unit stay. Cardiopulmonary complications are common. The management of patients with SAH focuses on the anticipat...

journal_title：Critical care medicine

authors： Diringer MN

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVES:To perform a complete immunological characterization of compensatory anti-inflammatory response syndrome in patients with sepsis and to explore the relationship between these changes and clinical outcomes of 28-day mortality and secondary infections. DESIGN:Prospective single-center study conducted between ...

journal_title：Critical care medicine

authors： Gomez HG,Gonzalez SM,Londoño JM,Hoyos NA,Niño CD,Leon AL,Velilla PA,Rugeles MT,Jaimes FA

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:To define changes in intramyocardial pH and PCO2 during cardiac arrest and resuscitation. DESIGN:Prospective and observational trial. SETTING:Mammalian research laboratory utilizing a porcine model of cardiac arrest. SUBJECTS:Sixteen domestic pigs. INTERVENTIONS:Ventricular fibrillation was induced by an ...

journal_title：Critical care medicine

authors： Kette F,Weil MH,Gazmuri RJ,Bisera J,Rackow EC

更新日期：1993-06-01 00:00:00

abstract：OBJECTIVES:To address the association between the 2003 heat wave in Paris (France) and the occurrence of out-of-hospital cardiac arrest. DESIGN:: An analysis of the interventions of the medical mobile intensive care units of the City of Paris for out-of-hospital cardiac arrest and prehospital myocardial infarctions, w...

journal_title：Critical care medicine

authors： Empana JP,Sauval P,Ducimetiere P,Tafflet M,Carli P,Jouven X

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVES:To determine the rate of unplanned PICU readmissions, examine the characteristics of index admissions associated with readmission, and compare outcomes of readmissions versus index admissions. DESIGN:Retrospective cohort analysis. SETTING:Ninety North American PICUs that participated in the Virtual Pediatr...

journal_title：Critical care medicine

authors： Edwards JD,Lucas AR,Stone PW,Boscardin WJ,Dudley RA

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:To determine whether naloxone administration after hemorrhagic shock has any beneficial or deleterious effect on immune responses. BACKGROUND DATA:Hemorrhagic shock is known to produce immunodepression in both humans and experimental animals. Although studies suggest that endogenous opioids play a role in im...

journal_title：Critical care medicine

authors： Wichmann MW,Zellweger R,Ayala A,Chaudry IH

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:To assess the statistical association of the Acute Physiology and Chronic Health Evaluation (APACHE II) score with multiple intervention and outcome variables in surgical ICU patients. DESIGN:Continuous data collection on every patient admitted to the surgical ICU for a 21-month period. MATERIALS AND METHOD...

journal_title：Critical care medicine

authors： Rutledge R,Fakhry SM,Rutherford EJ,Muakkassa F,Baker CC,Koruda M,Meyer AA

更新日期：1991-08-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to evaluate the long-term cardiopulmonary outcome at ages 10-15 yrs following neonatal extracorporeal membrane oxygenation (ECMO). The specific aims of the study were to assess baseline aerobic capacity, cardiac function, and pulmonary function in neonatal ECMO survivors using gr...

journal_title：Critical care medicine

authors： Boykin AR,Quivers ES,Wagenhoffer KL,Sable CA,Chaney HR,Glass P,Bahrami KR,Short BL

更新日期：2003-09-01 00:00:00

abstract：OBJECTIVE:To identify factors associated with granting or refusing intensive care unit (ICU) admission, to analyze ICU characteristics and triage decisions, and to describe mortality in admitted and refused patients. DESIGN:Observational, prospective, multiple-center study. SETTING:Four university hospitals and seven...

journal_title：Critical care medicine

authors： Garrouste-Orgeas M,Montuclard L,Timsit JF,Reignier J,Desmettre T,Karoubi P,Moreau D,Montesino L,Duguet A,Boussat S,Ede C,Monseau Y,Paule T,Misset B,Carlet J,French ADMISSIONREA Study Group.

更新日期：2005-04-01 00:00:00

abstract：OBJECTIVES:To compare the incidence of withdrawal or withholding of life support (WD/WHLS), and to identify similarities and differences in the process of the withdrawal of life support (WDLS) between teaching and community hospitals' intensive care units (ICUs). DESIGN:Prospective cohort study, with some data obtaine...

journal_title：Critical care medicine

authors： Keenan SP,Busche KD,Chen LM,Esmail R,Inman KJ,Sibbald WJ

更新日期：1998-02-01 00:00:00

abstract：OBJECTIVES:Over 2,500 children undergo hematopoietic stem cell transplantation in the United States each year, and up to 35% require PICU support for life-threatening complications. PICU mortality has dropped from 85% to 44%, but interpretation is confounded by significant cohort heterogeneity. Reports conflict regardi...

journal_title：Critical care medicine

authors： Zinter MS,Dvorak CC,Spicer A,Cowan MJ,Sapru A

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND AND METHODS:A study was performed to examine the effects of the calcium-channel blocker levemopamil on neurologic outcome and neuropathology in a clinically relevant model of complete global cerebral ischemia (ventricular fibrillation in cats). Levemopamil was administered to cats starting 5 mins after resus...

journal_title：Critical care medicine

authors： Fleischer JE,Nakakimura K,Drummond JC,Scheller MS,Zornow MH,Grafe MR,Shapiro HM

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:The Cardiac Arrhythmia Suppression Trial II showed that moricizine acutely increases the occurrence of sudden cardiac death. Thus the objective of this investigation was to evaluate the antifibrillatory properties of moricizine (a new antiarrhythmic agent) alone and in combination with lidocaine (an establish...

journal_title：Critical care medicine

authors： Ujhelyi MR,O'Rangers EA,Fan C,Kluger J,Chow MS

更新日期：1993-10-01 00:00:00

abstract：:The authors placed Swan-Ganz catheters in 11 preterm and 2 term infants with severe cardiopulmonary distress. The infants ranged in weight from 1100-4000 g. The procedure was performed in the neonatal ICU by jugular venous cutdown. Intracardiac pressures and oxygen saturations were measured in each chamber entered. Th...

journal_title：Critical care medicine

authors： Todres ID,Crone RK,Rogers MC,Shannon DC

更新日期：1979-08-01 00:00:00