Ligands of the receptor for advanced glycation end products, including high-mobility group box 1, limit bacterial dissemination during Escherichia coli peritonitis.

abstract：OBJECTIVE:To determine whether a cellular phone would interfere with the operation of mechanical ventilators. DESIGN:Laboratory study. SETTING:University medical center. SUBJECTS:Fourteen mechanical ventilators. INTERVENTIONS:We evaluated change in operation and malfunction of the mechanical ventilators. MEASUREME...

journal_title：Critical care medicine

authors： Shaw CI,Kacmarek RM,Hampton RL,Riggi V,El Masry A,Cooper JB,Hurford WE

更新日期：2004-04-01 00:00:00

abstract：OBJECTIVE:To compare the effects of cardiac surgery with and without extracorporeal circulation on the mechanics of the respiratory system, lung, and chest wall. We also determined the time course of those effects. DESIGN:Prospective, controlled study. SETTING:An eight-bed, cardiac-surgical intensive care unit at a u...

journal_title：Critical care medicine

authors： Roosens C,Heerman J,De Somer F,Caes F,Van Belleghem Y,Poelaert JI

更新日期：2002-11-01 00:00:00

abstract：:In order to examine the prognostic value of pulmonary arterial hypertension (PAH) in patients with moderate and severe acute respiratory failure (ARF), 225 patients with ARF who had been treated with mechanical ventilation and admitted to our ICU during a 3-yr period (January, 1983 to January, 1986) were prospectively...

journal_title：Critical care medicine

authors： Villar J,Blazquez MA,Lubillo S,Quintana J,Manzano JL

更新日期：1989-06-01 00:00:00

abstract：OBJECTIVES:Secretoneurin is associated with cardiomyocyte Ca handling and improves risk prediction in patients with acute myocardial dysfunction. Whether secretoneurin improves risk assessment on top of established cardiac biomarkers and European System for Cardiac Operative Risk Evaluation II in patients undergoing ca...

journal_title：Critical care medicine

authors： Brynildsen J,Petäjä L,Myhre PL,Lyngbakken MN,Nygård S,Stridsberg M,Christensen G,Ottesen AH,Pettilä V,Omland T,Røsjø H

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVES:To investigate whether admission B-type natriuretic peptide levels predict the development of acute kidney injury in acute coronary syndromes. DESIGN:Prospective study. SETTING:Single-center study, 13-bed intensive cardiac care unit at a University Cardiological Center. PATIENTS:Six-hundred thirty-nine ac...

journal_title：Critical care medicine

authors： Moltrasio M,Cabiati A,Milazzo V,Rubino M,De Metrio M,Discacciati A,Rumi P,Marana I,Marenzi G

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVES:Despite having dysregulated iron metabolism, critically ill patients may receive exogenous iron for the treatment of anemia. Iron is associated with increased tissue apoptosis and may facilitate bacterial growth. We hypothesized that exogenous iron administration given after the onset of sepsis would lead to...

journal_title：Critical care medicine

authors： Javadi P,Buchman TG,Stromberg PE,Husain KD,Dunne WM,Woolsey CA,Turnbull IR,Hotchkiss RS,Karl IE,Coopersmith CM

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVES:To characterize the rates of accidental removal of endotracheal tubes, nasogastric tubes, central venous catheters, and arterial catheters. To assess the efficacy of corrective measures aimed at reducing the accidental removal of these devices. DESIGN:Prospective, observational, and interventional study. S...

journal_title：Critical care medicine

authors： Carrión MI,Ayuso D,Marcos M,Paz Robles M,de la Cal MA,Alía I,Esteban A

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:To assess survival after cardiac arrest and to determine whether age is an independent determinant of late mortality or poor neurologic outcome. DESIGN:Analyses using results of Brain Resuscitation Clinical Trial I (1979 to 1984) and Brain Resuscitation Clinical Trial II (1984 to 1989), two randomized, doubl...

journal_title：Critical care medicine

authors： Rogove HJ,Safar P,Sutton-Tyrrell K,Abramson NS

更新日期：1995-01-01 00:00:00

abstract：OBJECTIVE:Rapid fluid loading is standard treatment for hypovolemia. Because volume expansion does not always improve hemodynamic status, predictive parameters of fluid responsiveness are needed. Passive leg raising is a reversible maneuver that mimics rapid volume expansion. Passive leg raising-induced changes in stro...

journal_title：Critical care medicine

authors： Préau S,Saulnier F,Dewavrin F,Durocher A,Chagnon JL

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVES:To outline both the preclinical and clinical data demonstrating surfactant alterations in acute lung injury, which provide the rationale for testing exogenous surfactant administration in this setting. We also review the results of the randomized, controlled clinical trials conducted to date that have evalua...

journal_title：Critical care medicine

authors： Lewis JF,Brackenbury A

更新日期：2003-04-01 00:00:00

abstract：:These guidelines were developed to provide a reference for preparing policies on admission and discharge for pediatric intensive care units (PICUs). They represent a consensus opinion of physicians, nurses, and allied health care professionals. By using this document as a framework for developing multidisciplinary adm...

journal_title：Critical care medicine

authors：

更新日期：1999-04-01 00:00:00

abstract：:Hemodynamic effects of controlled mechanical ventilation (CMV), intermittent mandatory ventilation (IMV), and intermittent mandatory ventilation with 5 cm H20 PEEP (IMV 5 peep) were studied in 20 patients after aortocoronary bypass surgery. Significant increases in cardiac index (CI) and stroke volume index (SI) (p le...

journal_title：Critical care medicine

authors： Mathru M,Rao TL,El-Etr AA,Pifarre R

更新日期：1982-07-01 00:00:00

abstract：OBJECTIVES:The potential advantages of lowering core temperature during sepsis are to lower energy requirement and to activate various cell-protecting pathways. We experimentally investigated whether postconditioning temperature modifications influence survival duration during experimental sepsis. DESIGN:A prospective...

journal_title：Critical care medicine

authors： L'Her E,Amerand A,Vettier A,Sebert P

更新日期：2006-10-01 00:00:00

abstract：:This study evaluated the effects of varying colloid concentrations and infusion volumes on survival and plasma volume expansion in rats subjected to an intestinal ischemic shock. Up to 10% solutions of albumin and dextran-40 in lactated Ringer's solution, infused over a 6-h period, had the same effects on hematocrit (...

journal_title：Critical care medicine

authors： Dawidson I,Ottosson J,Reisch J

更新日期：1985-09-01 00:00:00

abstract：OBJECTIVE:Hematopoietic stem cell transplant (HSCT) recipients admitted to the intensive care unit (ICU) have high mortality. The prognostic importance of peripheral blood stem cell source in critically ill HSCT recipients and the performance of Acute Physiology and Chronic Health Evaluation (APACHE) III have not been ...

journal_title：Critical care medicine

authors： Afessa B,Tefferi A,Dunn WF,Litzow MR,Peters SG

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to test the hypothesis that the right ventricle is more dilated during resuscitation from cardiac arrest caused by pulmonary embolism, compared with hypoxia and primary arrhythmia. DESIGN:Twenty-four pigs were anesthetized and cardiac arrest was induced using three different method...

journal_title：Critical care medicine

authors： Aagaard R,Caap P,Hansson NC,Bøtker MT,Granfeldt A,Løfgren B

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Subcutaneously administered low-molecular-weight heparins are widely used for prevention of venous thromboembolism. The appropriateness of the subcutaneous route in critically ill patients has never been established. OBJECTIVE:To determine anti-Xa activities in critically ill patients and in noncritically i...

journal_title：Critical care medicine

authors： Priglinger U,Delle Karth G,Geppert A,Joukhadar C,Graf S,Berger R,Hülsmann M,Spitzauer S,Pabinger I,Heinz G

更新日期：2003-05-01 00:00:00

abstract：OBJECTIVE:Life-threatening conditions cause severe changes in the organization and conformation of macromolecules, creating urgent requirements for protein repair to ensure survival. As molecular chaperones, heat shock proteins (HSP) that have specialized functions in protein folding are now well established to restore...

journal_title：Critical care medicine

authors： Christians ES,Yan LJ,Benjamin IJ

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:The antimetabolite drug, 5-fluorouracil, inhibits microbial growth. Coating of central venous catheters with 5-fluorouracil may reduce the risk of catheter infection. Our objective was to compare the safety and efficacy of central venous catheters externally coated with 5-fluorouracil with those coated with c...

journal_title：Critical care medicine

authors： Walz JM,Avelar RL,Longtine KJ,Carter KL,Mermel LA,Heard SO,5-FU Catheter Study Group.

更新日期：2010-11-01 00:00:00

abstract：OBJECTIVE:To determine recent trends in severe sepsis-related rates of hospitalization, mortality, and hospital case fatality in a large geographic area and to determine the impact of age, race, and gender on these outcomes. DESIGN:Trend analysis for the period of 1995 to 2002. SETTING:Acute care hospitals in New Jer...

journal_title：Critical care medicine

authors： Dombrovskiy VY,Martin AA,Sunderram J,Paz HL

更新日期：2005-11-01 00:00:00

abstract：OBJECTIVES:To outline the concepts involved in optimizing antibacterial dosing in critically ill patients with acute renal failure undergoing continuous renal replacement therapy (CRRT), provide a strategy for optimizing dosing, and summarize the data required to implement the strategy. DATA SOURCES:MEDLINE search fro...

journal_title：Critical care medicine

authors： Choi G,Gomersall CD,Tian Q,Joynt GM,Freebairn R,Lipman J

更新日期：2009-07-01 00:00:00

abstract：:Percutaneous cholecystostomy was employed successfully as an alternative to cholecystectomy for the treatment of acute cholecystitis with perforation in an elderly woman. The procedure, performed portably in the cardiac care unit, was selected because progressive cardiac and renal decompensation made the patient an ex...

journal_title：Critical care medicine

authors： Longmaid HE 3rd,Bassett JG,Gottlieb H

更新日期：1985-08-01 00:00:00

abstract：OBJECTIVE:To test whether intensive care unit (ICU) nasal screening for methicillin-resistant Staphylococcus aureus (MRSA) predicts the presence or absence of MRSA infections requiring antimicrobial treatment. DESIGN:A prospective cohort study. SETTING:Medical ICU at Barnes-Jewish Hospital, a 1252-bed urban teaching ...

journal_title：Critical care medicine

authors： Sarikonda KV,Micek ST,Doherty JA,Reichley RM,Warren D,Kollef MH

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:Neutropenia recovery may be associated with an increased risk of respiratory function deterioration. A history of pneumonia complicating neutropenia has been identified as the leading cause of adult respiratory distress syndrome during neutropenia recovery in patients receiving anticancer chemotherapy, sugges...

journal_title：Critical care medicine

authors： Azoulay E,Attalah H,Yang K,Herigault S,Jouault H,Brun-Buisson C,Brochard L,Harf A,Schlemmer B,Delclaux C

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Increased cardiac index, oxygen delivery (DO2), and oxygen consumption (VO2) patterns were shown to characterize the physiologic status of surviving high-risk surgical patients, and indicate increased metabolic needs; relatively normal DO2 and VO2 values were found to characterize the sequential pattern of n...

journal_title：Critical care medicine

authors： Shoemaker WC,Appel PL,Kram HB

更新日期：1991-05-01 00:00:00

abstract：OBJECTIVES:To evaluate the cardiovascular response and acute stress reaction after arousal induced by a benzodiazepine antagonist, flumazenil, in patients sedated with midazolam. DESIGN:Prospective study. SETTING:Emergency center in a university hospital. PATIENTS:A total of 12 patients were ventilated mechanically ...

journal_title：Critical care medicine

authors： Kamijo Y,Masuda T,Nishikawa T,Tsuruta H,Ohwada T

更新日期：2000-02-01 00:00:00

abstract：:Thoracic injuries are very common among trauma victims. This article reviews the current literature on the management of multiple aspects of the care of the patient with severe chest injury. The mechanics of chest injury are complex and varied. Chest wall injuries are the most common and noticeable manifestation of th...

journal_title：Critical care medicine

authors： Kiraly L,Schreiber M

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVES:To compare sleep, work hours, and behavioral alertness in faculty and fellows during a randomized trial of nighttime in-hospital intensivist staffing compared with a standard daytime intensivist model. DESIGN:Prospective observational study. SETTING:Medical ICU of a tertiary care academic medical center du...

journal_title：Critical care medicine

authors： Bakhru RN,Basner M,Kerlin MP,Halpern SD,Hansen-Flaschen J,Rosen IM,Dinges DF,Schweickert WD

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:To study whether noninvasive pressure support ventilation (NIPSV) with helium/oxygen (He/oxygen), which can reduce dyspnea, PaCO2, and work of breathing more than NIPSV with air/oxygen in decompensated chronic obstructive pulmonary disease, could have beneficial consequences on outcome and hospitalization cos...

journal_title：Critical care medicine

authors： Jolliet P,Tassaux D,Roeseler J,Burdet L,Broccard A,D'Hoore W,Borst F,Reynaert M,Schaller MD,Chevrolet JC

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVES:In patients with acute hypoxemic respiratory failure, noninvasive ventilation and high-flow nasal cannula oxygen are alternative strategies to conventional oxygen therapy. Endotracheal intubation is frequently needed in these patients with a risk of delay, and early predictors of failure may help clinicians ...

journal_title：Critical care medicine

authors： Frat JP,Ragot S,Coudroy R,Constantin JM,Girault C,Prat G,Boulain T,Demoule A,Ricard JD,Razazi K,Lascarrou JB,Devaquet J,Mira JP,Argaud L,Chakarian JC,Fartoukh M,Nseir S,Mercat A,Brochard L,Robert R,Thille AW,REV

更新日期：2018-02-01 00:00:00