Role of exogenous surfactant in acute lung injury.

abstract：OBJECTIVES:To identify and appraise articles describing criteria used to prioritize or withhold a critical care admission. DATA SOURCES:PubMed, Embase, Medline, EBM Reviews, and CINAHL Complete databases. Gray literature searches and a manual review of references were also performed. Preferred Reporting Items for Syst...

journal_title：Critical care medicine

authors： Dahine J,Hébert PC,Ziegler D,Chenail N,Ferrari N,Hébert R

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:Cerebral perfusion pressure<40 mm Hg following pediatric traumatic brain injury has been associated with increased mortality independent of age, and current guidelines recommend maintaining cerebral perfusion pressure between 40 mm Hg-60 mm Hg. Although adult traumatic brain injury studies have observed an in...

journal_title：Critical care medicine

authors： Friess SH,Smith C,Kilbaugh TJ,Frangos SG,Ralston J,Helfaer MA,Margulies SS

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:Cytokines and adhesion molecules have a decisive role in the development of early inflammatory response as well as the late sequelae of sepsis. Because L-selectin-deficient mice are protected from lethal endotoxemia, blockade of L-selectin may provide a useful therapeutic option in human sepsis. Heparin has i...

journal_title：Critical care medicine

authors： Derhaschnig U,Pernerstorfer T,Knechtelsdorfer M,Hollenstein U,Panzer S,Jilma B

更新日期：2003-04-01 00:00:00

abstract：:Fifteen patients with septic shock and perfusion failure received a 20-min infusion of glucose-insulin-potassium (GIK, glucose 50%, 1 g/kg body weight; insulin 1.5 U/kg, potassium, 10 mMol) after volume loading and vasoactive medication had failed to eliminate hypotension and lactacidemia. Hemodynamic and oxygen measu...

journal_title：Critical care medicine

authors： Bronsveld W,van den Bos GC,Thijs LG

更新日期：1985-07-01 00:00:00

abstract：OBJECTIVES:We sought to review findings from recent literature on the postresuscitation care of cardiac arrest patients using therapeutic hypothermia as part of nontrial treatment. DESIGN:Literature review. SETTING:Hospital-based environment. SUBJECTS:Patients initially resuscitated from cardiac arrest who underwent...

journal_title：Critical care medicine

authors： Sagalyn E,Band RA,Gaieski DF,Abella BS

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVES:Lung contusion is a major risk factor for the development of acute respiratory distress syndrome. We set to determine the role of toll-like receptor 3 and the binding of double-stranded RNA in the pathogenesis of sterile injury following lung contusion. DESIGN:Toll-like receptor 3 expression was analyzed in...

journal_title：Critical care medicine

authors： Suresh MV,Thomas B,Machado-Aranda D,Dolgachev VA,Kumar Ramakrishnan S,Talarico N,Cavassani K,Sherman MA,Hemmila MR,Kunkel SL,Walter NG,Hogaboam CM,Raghavendran K

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:To study the impact of diabetes mellitus on the relationship between glycemia and mortality in critically ill patients. DESIGN:Retrospective observational study. SETTING:Intensive care units of two university hospitals. PATIENTS:Cohort of 4946 critically ill patients including 728 patients with diabetes me...

journal_title：Critical care medicine

authors： Egi M,Bellomo R,Stachowski E,French CJ,Hart GK,Hegarty C,Bailey M

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVES:To evaluate the epidemiology of hyperammonemia unrelated to liver failure in the critical care setting. DESIGN:Retrospective case series. SETTING:Critically ill patients admitted to ICUs at Mayo Clinic, Rochester, MN (medical ICU, two mixed medical-surgical ICUs, coronary care unit, or the cardiosurgical I...

journal_title：Critical care medicine

authors： Sakusic A,Sabov M,McCambridge AJ,Rabinstein AA,Singh TD,Mukesh K,Kashani KB,Cook D,Gajic O

更新日期：2018-09-01 00:00:00

abstract：:The relationship between oxygen uptake (Vo2) and delivery (Do2) was examined in 64 patients immediately after cardiopulmonary bypass. In 44 patients with lactate levels below 2.5 mmol/L, Vo2 decreased proportionally when Do2 decreased below 300 ml/min X m2. At a Do2 over this level, Vo2 plateaued at 105 +/- 13 (SD) ml...

journal_title：Critical care medicine

authors： Komatsu T,Shibutani K,Okamoto K,Kumar V,Kubal K,Sanchala V,Lees DE

更新日期：1987-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the role of cholesterol and lipoproteins in children with severe meningococcal sepsis. DESIGN:Retrospective observational study. SETTING:A university-affiliated pediatric intensive care unit. PATIENTS:Fifty-seven patients admitted to the pediatric intensive care unit with meningococcal sepsis o...

journal_title：Critical care medicine

authors： Vermont CL,den Brinker M,Kâkeci N,de Kleijn ED,de Rijke YB,Joosten KF,de Groot R,Hazelzet JA

更新日期：2005-07-01 00:00:00

abstract：:The recommended rates for closed-chest cardiac compressions during CPR are based on physiologic variations with increasing age rather than experimental data. Using puppies, we compared mean arterial pressure, cardiac index (CI), and cerebral blood flow (CBF) at a slow (40/min, group 1) and a rapid (120/min, group 2) r...

journal_title：Critical care medicine

authors： Fleisher G,Delgado-Paredes C,Heyman S

更新日期：1987-10-01 00:00:00

abstract：OBJECTIVE:The use of corticosteroids in patients with sepsis or septic shock has been controversial for many decades. Clinical studies have reported beneficial, as well as negative results. We conducted a meta-analysis to assess the clinical evidence and to evaluate treatment effects in specific subgroups of patients. ...

journal_title：Critical care medicine

authors： Lefering R,Neugebauer EA

更新日期：1995-07-01 00:00:00

abstract：OBJECTIVE:Develop a scoring system that can assess the management of septic shock by individuals and teams. DESIGN:Retrospective review of videotapes of critical care house staff managing a standardized simulation of septic shock. SETTING:Academic medical center; videotapes were made in a recreated intensive care uni...

journal_title：Critical care medicine

authors： Ottestad E,Boulet JR,Lighthall GK

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVE:To determine whether four stages of weaning (acute, prewean, wean, and outcome) could be identified by using clinical instruments designed to quantify severity of illness, patient stability, or weaning readiness. The instruments used were the Acute Physiology and Chronic Health Evaluation (APACHE III), the Th...

journal_title：Critical care medicine

authors： Burns SM,Ryan B,Burns JE

更新日期：2000-07-01 00:00:00

abstract：OBJECTIVE:To determine the effects of accidental injury of varying severity on interleukin (IL)-1 alpha, IL-6, IL-8, tumor necrosis factor-alpha (TNF-alpha), and endotoxin release. DESIGN:Prospective, multi-unit, longitudinal study. SETTING:Emergency Departments and intensive care units of two university hospitals. ...

journal_title：Critical care medicine

authors： Hoch RC,Rodriguez R,Manning T,Bishop M,Mead P,Shoemaker WC,Abraham E

更新日期：1993-06-01 00:00:00

abstract：UNLABELLED:Meningococcal septic shock (MSS) has high mortality and morbidity rates. In addition to the traditional prompt antibiotics and respiratory and circulatory support, new treatment strategies have been proposed. AGAINST THE INFLAMMATORY CASCADE:Immunotherapy, such as antiserum to Escherichia coli J5 and human ...

journal_title：Critical care medicine

authors： Leclerc F,Leteurtre S,Cremer R,Fourier C,Sadik A

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVE:To determine the number of adult or pediatric intensive care unit patients without documented invasive fungal infection who receive systemic antifungal therapy. DESIGN:A 1-day cross-sectional cohort study. SETTING:One hundred sixty-nine intensive care units in France and Belgium. PATIENTS:All patients stay...

journal_title：Critical care medicine

authors： Azoulay E,Dupont H,Tabah A,Lortholary O,Stahl JP,Francais A,Martin C,Guidet B,Timsit JF

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVE:To examine the effects of hypertonic (7.5%) saline-6% dextran 70 (HSD) and isotonic (0.9%) saline-6% dextran 70 (ISD) on cardiovascular function and intestinal perfusion in experimental endotoxin shock. DESIGN:Experimental, randomized, unblinded, interventional study. SETTING:University experimental animal ...

journal_title：Critical care medicine

authors： Oi Y,Aneman A,Svensson M,Ewert S,Dahlqvist M,Haljamäe H

更新日期：2000-08-01 00:00:00

abstract：OBJECTIVE:To compare the ability of two methods--Acute Physiology and Chronic Health Evaluation (APACHE II) and Mortality Prediction Model (MPM)--to predict hospital outcome for a large group of intensive care patients from Britain and Ireland. DESIGN:Prospective, multicenter, cohort study. SETTING:Twenty-six general...

journal_title：Critical care medicine

authors： Rowan KM,Kerr JH,Major E,McPherson K,Short A,Vessey MP

更新日期：1994-09-01 00:00:00

abstract：OBJECTIVE:This study determined the time course for inhibition of lipopolysaccharide-induced acute lung injury following a single dose of genistein. In addition, the study investigated whether a multiple dosing schedule with genistein retained the inhibitory effects on acute lung injury, nuclear factor-kappaB activatio...

journal_title：Critical care medicine

authors： Kang JL,Lee HW,Lee HS,Pack IS,Castranova V,Koh Y

更新日期：2003-02-01 00:00:00

abstract：:Prolonged therapeutic paralysis with pancuronium is commonly used in ICUs to facilitate mechanical ventilation of patients with respiratory failure. Sedation is usually given concomitantly to reduce patient discomfort, but assessment of its adequacy is made difficult by the paralysis. We recently cared for a former IC...

journal_title：Critical care medicine

authors： Parker MM,Schubert W,Shelhamer JH,Parrillo JE

更新日期：1984-01-01 00:00:00

abstract：OBJECTIVE:To assess the efficacy of bulk diffusion in maintaining oxygenation during apnea testing for brain death. DESIGN:Case series. SETTING:ICU in a primary care hospital. PATIENTS:Twenty-four consecutive patients with suspected brain death. Most patients suffered cerebral trauma from vehicular accidents. INTER...

journal_title：Critical care medicine

authors： al Jumah M,McLean DR,al Rajeh S,Crow N

更新日期：1992-11-01 00:00:00

abstract：OBJECTIVE:To determine the relationship between sublingual and intestinal mucosal microcirculatory perfusion. DESIGN:Observational, experimental study. SETTING:University-affiliated large animal laboratory. SUBJECTS:Ten fasted, anesthetized, mechanically ventilated, male pigs randomized to a sham group (n = 3) or to...

journal_title：Critical care medicine

authors： Verdant CL,De Backer D,Bruhn A,Clausi CM,Su F,Wang Z,Rodriguez H,Pries AR,Vincent JL

更新日期：2009-11-01 00:00:00

abstract：OBJECTIVES:To evaluate the impact of a comprehensive unit-based safety program on safety climate in a large cohort of intensive care units participating in the Keystone intensive care unit project. DESIGN/SETTING:A prospective cohort collaborative study to improve quality of care and safety culture by implementing and...

journal_title：Critical care medicine

authors： Sexton JB,Berenholtz SM,Goeschel CA,Watson SR,Holzmueller CG,Thompson DA,Hyzy RC,Marsteller JA,Schumacher K,Pronovost PJ

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:The flow rate of a liquid drainage from the lungs is limited because of the elastic nature of the airways. This study was designed to clarify the relationship between intrapulmonary liquid volume and the development of the flow limitation or choked flow phenomenon as a function of expiratory flow rate during ...

journal_title：Critical care medicine

authors： Baba Y,Brant D,Brah SS,Grotberg J,Bartlett RH,Hirschl RB

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVES:Racial/ethnic differences in palliative care resource use after stroke have been recognized, but it is unclear whether patient or hospital characteristics drive this disparity. We sought to determine whether palliative care use after intracerebral hemorrhage and ischemic stroke differs between hospitals serv...

journal_title：Critical care medicine

authors： Faigle R,Ziai WC,Urrutia VC,Cooper LA,Gottesman RF

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVES:To assess the feasibility, biochemical efficacy, and safety of liberal versus conventional glucose control in ICU patients with diabetes. DESIGN:Prospective, open-label, sequential period study. SETTING:A 22-bed mixed ICU of a tertiary hospital in Australia. PATIENTS:We compared 350 consecutive patients w...

journal_title：Critical care medicine

authors： Luethi N,Cioccari L,Biesenbach P,Lucchetta L,Kagaya H,Morgan R,Di Muzio F,Presello B,Gaafar D,Hay A,Crisman M,Toohey R,Russell H,Glassford NJ,Eastwood GM,Ekinci EI,Deane AM,Bellomo R,Mårtensson J

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVE:We investigated whether serum levels of neuron-specific enolase (NSE) and S-100beta protein could be used to evaluate cerebral injury and to predict outcome in severe sepsis and severe septic shock. DESIGN:Prospective study. SETTING:University hospital. PATIENTS AND MEASUREMENTS:In 170 consecutively enroll...

journal_title：Critical care medicine

authors： Nguyen DN,Spapen H,Su F,Schiettecatte J,Shi L,Hachimi-Idrissi S,Huyghens L

更新日期：2006-07-01 00:00:00

abstract：:Last year, >28,000 people received organ transplants from >14,000 donors in the United States. Unfortunately, the wait list now tops 91,000, with the gap between recipient needs and available donor organs at around 60,000. This has motivated a host of efforts to increase organ supply, including driver's license and do...

journal_title：Critical care medicine

authors： Aulisio MP,Devita M,Luebke D

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVE:To determine the effects of stimulation of vascular dopaminergic receptor subtype 1 (dopamine-1) receptors in the renal and mesenteric vascular beds of a neonatal model. DESIGN:Prospective, unblinded, dose-response evaluation in an awake animal. SETTING:University research laboratory. SUBJECTS:Thirty newbo...

journal_title：Critical care medicine

authors： Pearson RJ,Barrington KJ,Jirsch DW,Cheung PY

更新日期：1996-10-01 00:00:00