Dobutamine: a hemodynamic evaluation in pulmonary embolism shock.

Abstract:

:Intravenous dobutamine was used in ten patients requiring aggressive therapy for massive pulmonary embolism with circulatory failure. Except in one patient who rapidly died, a 30-min dobutamine infusion (8.3 +/- 2.7 micrograms/kg . min) increased both cardiac index (from 1.7 +/- 0.4 to 2.3 +/- 0.6 L/min . m2, p less than .001) and stroke index (from 16.6 +/- 6.7 to 21 +/- 5 ml/m2, p less than .01), and also reduced pulmonary vascular resistance. Additional hemodynamic improvement was observed until weaning from dobutamine, which was successfully completed 3.3 +/- 0.9 days after the start of infusion.

journal_name

Crit Care Med

journal_title

Critical care medicine

authors

Jardin F,Genevray B,Brun-Ney D,Margairaz A

doi

10.1097/00003246-198512000-00004

subject

Has Abstract

pub_date

1985-12-01 00:00:00

pages

1009-12

issue

12

eissn

0090-3493

issn

1530-0293

journal_volume

13

pub_type

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