Acute care/blood gas laboratories: profile of current operations.

abstract：OBJECTIVES:Delirium occurs in approximately 30% of critically ill patients, and the risk of dying during admission doubles in those patients. Molecular mechanisms causing delirium are largely unknown. However, critical illness and the ICU environment consistently disrupt circadian rhythms, and circadian disruptions are...

journal_title：Critical care medicine

authors： Gile J,Scott B,Eckle T

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVE:Anesthetic preconditioning appears to be a viable strategy to treat ischemic cerebral injury. Here we investigated 1) whether the protection conferred by sevoflurane preconditioning sustains in time; 2) whether sevoflurane preconditioning diminishes mitochondrial dysfunction following cerebral ischemia; and 3...

journal_title：Critical care medicine

authors： Ye R,Yang Q,Kong X,Li N,Zhang Y,Han J,Xiong L,Liu X,Zhao G

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVES:Glucose is the primary substrate for the energy requirements of the nervous system. Nevertheless, administration of glucose to critically ill patients with central nervous system trauma may have adverse effects on their neurologic recovery. The purpose of this study was to evaluate the effects of other sourc...

journal_title：Critical care medicine

authors： Cherian L,Peek K,Robertson CS,Goodman JC,Grossman RG

更新日期：1994-11-01 00:00:00

abstract：OBJECTIVE:Exosomes are small, cell-released vesicles (40-100 nm in size) with the potential to transfer proteins, lipids, small RNAs, messenger RNAs, or DNA between cells via interstitial fluids. Due to their role in tissue homeostasis, exosomes have emerged as a new type of therapeutic and diagnostic (theranostic) too...

journal_title：Critical care medicine

authors： Terrasini N,Lionetti V

更新日期：2017-06-01 00:00:00

abstract：:The authors determined the correction factor (Ct) for three sizes of commonly available central venous catheters. These catheters are used as the injectate catheter when a 2.5 Fr transthoracic thermistor is used to determine cardiac output by thermodilution. The valves for Ct were highly reproducible. These determinat...

journal_title：Critical care medicine

authors： Baskoff JD,Maruschak GF

更新日期：1981-12-01 00:00:00

abstract：OBJECTIVE:Critical care medicine trainees and faculty must acquire and maintain the skills necessary to provide state-of-the art clinical care to critically ill patients, to improve patient outcomes, optimize intensive care unit utilization, and continue to advance the theory and practice of critical care medicine. Thi...

journal_title：Critical care medicine

authors： Dorman T,Angood PB,Angus DC,Clemmer TP,Cohen NH,Durbin CG Jr,Falk JL,Helfaer MA,Haupt MT,Horst HM,Ivy ME,Ognibene FP,Sladen RN,Grenvik AN,Napolitano LM,American College of Critical Care Medicine.

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVES:To review the immunologic role of the cytokines and the specific role that tumor necrosis factor (TNF) plays in response to infection. The influence of bacterial lipopolysaccharide on TNF, the cytokine cascade, and resultant pathologies are also reviewed. DATA SOURCES:A MEDLINE search of the international E...

journal_title：Critical care medicine

authors： Beutler B,Grau GE

更新日期：1993-10-01 00:00:00

abstract：OBJECTIVES:Peripherally inserted central catheters are increasingly used in ICU as an alternative to centrally inserted central catheters for IV infusion. However, their reliability for hemodynamic measurements with transpulmonary thermodilution is currently unknown. We investigated the agreement between transpulmonary...

journal_title：Critical care medicine

authors： D'Arrigo S,Sandroni C,Cacciola S,Dell'Anna AM,Pittiruti M,Annetta MG,Colosimo C,Antonelli M

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:To review the physiology of the regulation and determinants of heart rate and the significance in the management of critically ill patients. DATA SOURCES:The MEDLINE database, references from selected articles, and the author's personal database. DATA SYNTHESIS:This review begins with the regulation of card...

journal_title：Critical care medicine

authors： Magder SA

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To compare the effects of cardiac surgery with and without extracorporeal circulation on the mechanics of the respiratory system, lung, and chest wall. We also determined the time course of those effects. DESIGN:Prospective, controlled study. SETTING:An eight-bed, cardiac-surgical intensive care unit at a u...

journal_title：Critical care medicine

authors： Roosens C,Heerman J,De Somer F,Caes F,Van Belleghem Y,Poelaert JI

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVES:To perform a scoping literature review of cognitive, psychiatric, and quality of life outcomes in adults undergoing extracorporeal membrane oxygenation for any indication. DATA SOURCES:We searched PubMed, EMBASE, Cochrane Library, Web of Science, CINAHL, and PsycINFO from inception to June 2019. STUDY SELE...

journal_title：Critical care medicine

authors： Khan IR,Saulle M,Oldham MA,Weber MT,Schifitto G,Lee HB

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:To determine whether four stages of weaning (acute, prewean, wean, and outcome) could be identified by using clinical instruments designed to quantify severity of illness, patient stability, or weaning readiness. The instruments used were the Acute Physiology and Chronic Health Evaluation (APACHE III), the Th...

journal_title：Critical care medicine

authors： Burns SM,Ryan B,Burns JE

更新日期：2000-07-01 00:00:00

abstract：OBJECTIVE:To determine xanthine oxidase activity, free radical concentrations, and lipid peroxidation in patients with sepsis syndrome compared with noninfected critically ill patients. DESIGN:A prospective observational study. SETTING:A nine-bed intensive care unit in a university teaching hospital trust. PATIENTS:...

journal_title：Critical care medicine

authors： Galley HF,Davies MJ,Webster NR

更新日期：1996-10-01 00:00:00

abstract：OBJECTIVE:Sepsis remains a major health threat in intensive care medicine. The renin-angiotensin system (ACE) affects inflammatory responses. In addition, angiotensin-converting enzyme inhibitors act to ameliorate lung injury. To investigate whether the widely used ACE inhibitor enalapril, used to treat hypertension, c...

journal_title：Critical care medicine

authors： Hagiwara S,Iwasaka H,Matumoto S,Hidaka S,Noguchi T

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:The administration of vasopressin during cardiopulmonary resuscitation (CPR) provides significantly more vital organ blood flow when compared with epinephrine during cardiac arrest in pigs. The effects of this potent vasoconstrictor on postresuscitation cardiovascular function remain unknown. The purpose of t...

journal_title：Critical care medicine

authors： Prengel AW,Lindner KH,Keller A,Lurie KG

更新日期：1996-12-01 00:00:00

abstract：:Comparative hemodynamic measurements recorded in 19 cases of septic shock associated with Neisseria meningitidis bacteremia and in 20 shock cases associated with bacteremia due to other Gram-negative bacilli showed a significantly higher incidence of early myocardial depression in the cases with meningococcal infectio...

journal_title：Critical care medicine

authors： Monsalve F,Rucabado L,Salvador A,Bonastre J,Cuñat J,Ruano M

更新日期：1984-12-01 00:00:00

abstract：OBJECTIVE:Insulin reduces morbidity and mortality among critically ill patients, but the molecular mechanisms of its effect remain unknown. Insulin is a well-known inhibitor of glycogen synthase kinase-3, which may play an important role in systemic inflammation and shock. Here we investigate the role of blood glucose ...

journal_title：Critical care medicine

authors： Dugo L,Collin M,Allen DA,Murch O,Foster SJ,Yaqoob MM,Thiemermann C

更新日期：2006-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the effects of monoclonal antibody to tumor necrosis factor (TNF)-alpha on the hemodynamic alterations and survival rate in rats subjected to intestinal ischemia/reperfusion. DESIGN:Prospective, randomized study. SETTING:Animal laboratory of an institute for research in traumatology. SUBJECTS:M...

journal_title：Critical care medicine

authors： Yao YM,Bahrami S,Redl H,Schlag G

更新日期：1996-09-01 00:00:00

abstract：OBJECTIVE:This pilot study was designed to identify which contextual factors facilitate/hinder the implementation of the awakening, breathing, coordination, delirium, and early mobility (ABCDE) bundle for guidance in future studies. DESIGN:The sources of data for this study included document review, planned site visit...

journal_title：Critical care medicine

authors： Carrothers KM,Barr J,Spurlock B,Ridgely MS,Damberg CL,Ely EW

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Hemorrhage in trauma is a significant challenge, accounting for 30% to 40% of all fatalities, second only to central nervous system injury as a cause of death. However, hemorrhagic death is the leading preventable cause of mortality in combat casualties and typically occurs within 6 to 24 hrs of injury. In c...

journal_title：Critical care medicine

authors： Perkins JG,Cap AP,Weiss BM,Reid TJ,Bolan CD

更新日期：2008-07-01 00:00:00

abstract：:This review focuses on the effects of restoring hormonal levels and/or influence on muscle protein metabolism in the stressed state. We have highlighted our clinical experience in the administration of anabolic and anticatabolic agents in stressed clinical populations, primarily adult and pediatric burn injury, as wel...

journal_title：Critical care medicine

authors： Ferrando AA,Wolfe RR

更新日期：2007-09-01 00:00:00

abstract：:Nine ventilator-dependent patients were successfully weaned from mechanical ventilatory support by high-frequency jet ventilation. All patients had been on ventilatory support for at least 2 wk, and had not responded to attempts at weaning by intermittent mandatory ventilation. ...

journal_title：Critical care medicine

authors： Klain M,Kalla R,Sladen A,Guntupalli K

更新日期：1984-09-01 00:00:00

abstract：:Ethical decision-making for the care of the critically ill and injured has never been more difficult than it is today. Major technologic advances prolong life but often provide questionable benefit in human terms. Both the ethical commitment to the individual patient and the competition for access to expensive and sca...

journal_title：Critical care medicine

authors： Weil MH,Weil CJ,Rackow EC

更新日期：1988-06-01 00:00:00

abstract：OBJECTIVE:To evaluate the prevalence and magnitude of weakness in patients receiving chronic mechanical ventilation and the impact of providing aggressive whole-body rehabilitation on conventional weaning variables, muscle strength, and overall functional status. DESIGN:Retrospective analysis of 49 consecutive patient...

journal_title：Critical care medicine

authors： Martin UJ,Hincapie L,Nimchuk M,Gaughan J,Criner GJ

更新日期：2005-10-01 00:00:00

abstract：OBJECTIVE:To determine whether mechanical ventilation using high tidal volume is associated with nonpulmonary organ dysfunction that can be attenuated by dexamethasone. DESIGN:Prospective randomized animal intervention study. SETTING:Animal care facility in a university hospital. SUBJECTS:Sedated and tracheostomized...

journal_title：Critical care medicine

authors： Nin N,Peñuelas O,de Paula M,Lorente JA,Fernández-Segoviano P,Esteban A

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Although survival is traditionally modeled using Cox proportional hazards modeling, this approach may be inappropriate in sepsis, in which the proportional hazards assumption does not hold. Newer, more flexible models, such as Gray's model, may be more appropriate. OBJECTIVES:To construct and compare Gray's...

journal_title：Critical care medicine

authors： Kasal J,Jovanovic Z,Clermont G,Weissfeld LA,Kaplan V,Watson RS,Angus DC

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVES:To compare the effects of two lung-protective ventilation strategies on pulmonary vascular mechanics in early acute respiratory distress syndrome. DESIGN:Experimental study. SETTING:University animal research laboratory. SUBJECTS:Twelve pigs (30.8 ± 2.5 kg). INTERVENTIONS:Acute respiratory distress syndr...

journal_title：Critical care medicine

authors： Santos A,Gomez-Peñalver E,Monge-Garcia MI,Retamal J,Borges JB,Tusman G,Hedenstierna G,Larsson A,Suarez-Sipmann F

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVES:There is growing recognition that high-quality care for patients and families in the ICU requires exemplary interprofessional collaboration and communication. One important aspect is how the ICU team makes complex decisions. However, no recommendations have been published on interprofessional shared decision...

journal_title：Critical care medicine

authors： Michalsen A,Long AC,DeKeyser Ganz F,White DB,Jensen HI,Metaxa V,Hartog CS,Latour JM,Truog RD,Kesecioglu J,Mahn AR,Curtis JR

更新日期：2019-09-01 00:00:00

abstract：:Position of the CVP port on a flow-directed balloon-tip pulmonary arterial catheter affects the accuracy of both thermodilution cardiac output determinations and CVP measurements. Systemic allometry (the study of the growth of a part in relation to the total organism) has been used to determine an easily measured inde...

journal_title：Critical care medicine

authors： Borland LM

更新日期：1986-11-01 00:00:00

abstract：OBJECTIVE:We tested whether mild hypothermia impacts on circulatory and respiratory dysfunction during experimental endotoxemia. DESIGN:Randomized controlled prospective experimental study. SETTING:Large animal facility, Medical University of Graz, Austria. SUBJECTS:Thirteen anesthetized and mechanically ventilated ...

journal_title：Critical care medicine

authors： Schwarzl M,Seiler S,Wallner M,von Lewinski D,Huber S,Maechler H,Steendijk P,Zelzer S,Truschnig-Wilders M,Obermayer-Pietsch B,Lueger A,Pieske BM,Post H

更新日期：2013-12-01 00:00:00