Impact of whole-body rehabilitation in patients receiving chronic mechanical ventilation.

abstract：OBJECTIVE:Exosomes are small, cell-released vesicles (40-100 nm in size) with the potential to transfer proteins, lipids, small RNAs, messenger RNAs, or DNA between cells via interstitial fluids. Due to their role in tissue homeostasis, exosomes have emerged as a new type of therapeutic and diagnostic (theranostic) too...

journal_title：Critical care medicine

authors： Terrasini N,Lionetti V

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVES:: To determine the relationship between intra-abdominal sepsis-induced high mobility group-box 1 and diaphragm contractile performance and to determine the inhibitory effects of antibodies for high mobility group-box 1 and receptor for advanced glycation end-products on septic peritonitis-induced diaphragmat...

journal_title：Critical care medicine

authors： Susa Y,Masuda Y,Imaizumi H,Namiki A

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:The adrenal gland is the endocrine organ most commonly involved in patients infected with human immunodeficiency virus (HIV). It is important to recognize patients with adrenal insufficiency, because this disorder may be fatal if untreated. The incidence of adrenal insufficiency in critically ill HIV-infected...

journal_title：Critical care medicine

authors： Marik PE,Kiminyo K,Zaloga GP

更新日期：2002-06-01 00:00:00

abstract：:There is an increasing evidence that survivors of critical illness suffer from impaired health-related quality of life. There are relatively few studies that have evaluated the effect of interventions in clinical trials to improve these long-term outcomes. Studies to improve long-term outcomes after critical illness f...

journal_title：Critical care medicine

authors： Rubenfeld GD

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that therapeutic hypercapnia enhances the proinflammatory responses to endotoxemia in the lung and spleen of rats. DESIGN:Prospective randomized study. SETTINGS:Hospital research institute. SUBJECTS:Forty-eight adult male rats. INTERVENTIONS:Rats were randomly assigned for a 24-hr p...

journal_title：Critical care medicine

authors： Norozian FM,Leoncio M,Torbati D,Meyer K,Raszynski A,Totapally BR

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVES:To compare the incidence of withdrawal or withholding of life support (WD/WHLS), and to identify similarities and differences in the process of the withdrawal of life support (WDLS) between teaching and community hospitals' intensive care units (ICUs). DESIGN:Prospective cohort study, with some data obtaine...

journal_title：Critical care medicine

authors： Keenan SP,Busche KD,Chen LM,Esmail R,Inman KJ,Sibbald WJ

更新日期：1998-02-01 00:00:00

abstract：OBJECTIVES:Palliative care is now recognized as an essential component of comprehensive care in serious illness that interferes with quality of life. We explored utilization of palliative care in spontaneous intracerebral hemorrhage at a population level using a large national database. DESIGN:Population based cross-s...

journal_title：Critical care medicine

authors： Murthy SB,Moradiya Y,Hanley DF,Ziai WC

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVES:To measure temporal trends in survival over time in people with severe coronavirus disease 2019 requiring critical care (high dependency unit or ICU) management, and to assess whether temporal variation in mortality was explained by changes in patient demographics and comorbidity burden over time. DESIGN:Re...

journal_title：Critical care medicine

authors： Dennis JM,McGovern AP,Vollmer SJ,Mateen BA

更新日期：2021-02-01 00:00:00

abstract：OBJECTIVES:Peripherally inserted central catheters are increasingly used in ICU as an alternative to centrally inserted central catheters for IV infusion. However, their reliability for hemodynamic measurements with transpulmonary thermodilution is currently unknown. We investigated the agreement between transpulmonary...

journal_title：Critical care medicine

authors： D'Arrigo S,Sandroni C,Cacciola S,Dell'Anna AM,Pittiruti M,Annetta MG,Colosimo C,Antonelli M

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:To test the reliability and validity of a modified moral distress tool, originally developed for the nursing profession, on respiratory care practitioners. To describe the relationship between moral distress, career dissatisfaction, and job turnover in respiratory care. DESIGN:A 28-question survey was develo...

journal_title：Critical care medicine

authors： Schwenzer KJ,Wang L

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:Leucine-rich repeat and immunoglobulin domain-containing protein (LINGO)-1 is expressed in neural stem cells, and its neutralization results in sustained neuronal immaturity. Thus, targeted inhibition of LINGO-1 via RNA interference may enhance transplanted neural stem cell survival and neuronal differentiati...

journal_title：Critical care medicine

authors： Chen N,Cen JS,Wang J,Qin G,Long L,Wang L,Wei F,Xiang Q,Deng DY,Wan Y

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:During cardiopulmonary bypass, inflammation and immunosuppression is present. We measured circulating mediators and monocyte-based functions and tested the hypothesis that these variables are influenced by methylprednisolone (MP) or tirilazad mesylate (TM) treatment. DESIGN:Randomized, controlled, double-bli...

journal_title：Critical care medicine

authors： Volk T,Schmutzler M,Engelhardt L,Döcke WD,Volk HD,Konertz W,Kox WJ

更新日期：2001-11-01 00:00:00

abstract：OBJECTIVES:The main objective of the study was to determine the prevalence of venous thromboembolism events in patients infected with severe acute respiratory syndrome coronavirus 2 requiring venovenous extracorporeal membrane oxygenation. The secondary objective was to compare venous thromboembolism events and coagula...

journal_title：Critical care medicine

authors： Parzy G,Daviet F,Puech B,Sylvestre A,Guervilly C,Porto A,Hraiech S,Chaumoitre K,Papazian L,Forel JM

更新日期：2020-10-01 00:00:00

abstract：:A patient with neurogenic pulmonary edema was successfully treated with the alpha-blocking agent, chlorpromazine. A pathophysiologic basis for this drug's efficacy is discussed. ...

journal_title：Critical care medicine

authors： Wohns RN,Tamas L,Pierce KR,Howe JF

更新日期：1985-03-01 00:00:00

abstract：OBJECTIVE:To explore ethnic differences in do-not-resuscitate orders after intracerebral hemorrhage. DESIGN:Population-based surveillance. SETTING:Corpus Christi, Texas. PATIENTS:All cases of intracerebral hemorrhage in the community of Corpus Christi, TX were ascertained as part of the Brain Attack Surveillance in ...

journal_title：Critical care medicine

authors： Zahuranec DB,Brown DL,Lisabeth LD,Gonzales NR,Longwell PJ,Smith MA,Garcia NM,Morgenstern LB

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Resuscitation from hemorrhagic shock (HS) predisposes to subsequent infections. Susceptibility to infection following sepsis has been attributed to apoptosis. Interleukin (IL)-6 has been shown to have antiapoptotic properties and to decrease postresuscitation inflammation in rodent and porcine models of HS. ...

journal_title：Critical care medicine

authors： Arikan AA,Yu B,Mastrangelo MA,Tweardy DJ

更新日期：2006-03-01 00:00:00

abstract：OBJECTIVES:Atrial fibrillation is frequently seen in sepsis-related hospitalizations. However, large-scale contemporary data from the United States comparing outcomes among sepsis-related hospitalizations with versus without atrial fibrillation are limited. The aim of our study was to assess the frequency of atrial fib...

journal_title：Critical care medicine

authors： Desai R,Hanna B,Singh S,Omar A,Deshmukh A,Kumar G,Foreman MG,Sachdeva R

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to evaluate the relative frequency of pediatric in-hospital cardiopulmonary resuscitation events occurring in ICUs compared to general wards. We hypothesized that the proportion of pediatric cardiopulmonary resuscitation provided in ICUs versus general wards has increased over the p...

journal_title：Critical care medicine

authors： Berg RA,Sutton RM,Holubkov R,Nicholson CE,Dean JM,Harrison R,Heidemann S,Meert K,Newth C,Moler F,Pollack M,Dalton H,Doctor A,Wessel D,Berger J,Shanley T,Carcillo J,Nadkarni VM,Eunice Kennedy Shriver National Institute

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:High-frequency oscillation has been proposed for use in adult acute respiratory distress syndrome. However, limited data are available on the effect of pressure amplitude and rate (Hz) on tidal volumes delivered during high-frequency oscillation in adults. DESIGN:Prospective, animal model, lung injury study....

journal_title：Critical care medicine

authors： Sedeek KA,Takeuchi M,Suchodolski K,Kacmarek RM

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:To elucidate sources of variability in the estimate of treatment effects in a successful phase 3 trial in severe sepsis and to assess their implications on the design of future clinical trials. DESIGN:Retrospective evaluation of prospectively defined subgroups from a large phase 3, placebo-controlled clinica...

journal_title：Critical care medicine

authors： Macias WL,Vallet B,Bernard GR,Vincent JL,Laterre PF,Nelson DR,Derchak PA,Dhainaut JF

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVE:To determine the effect of a bolus infusion of diaspirin cross-linked hemoglobin (DCLHb or hemoglobin crosfumaril) on the ileal mucosal microcirculation in septic rats. DESIGN:Prospective, randomized, single-blinded study. SETTING:University-affiliated animal research laboratory. SUBJECTS:Twenty-four male ...

journal_title：Critical care medicine

authors： Sielenkämper AW,Eichelbrönner O,Martin CM,Madorin SW,Chin-Yee IH,Sibbald WJ

更新日期：2000-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the effects of sympathetic and parasympathetic nervous system activity on the heart rate and other hemodynamic variables in acute emergency patients with mild to moderately severe trauma. DESIGN:Clinical study. SETTING:Level 1 university-run trauma service. PATIENTS:Fourteen trauma patients stu...

journal_title：Critical care medicine

authors： Fathizadeh P,Shoemaker WC,Wo CC,Colombo J

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVE:Transarterial chemoembolization is a widely used therapy for the treatment of hepatocellular carcinoma. A rare adverse event is acute respiratory distress syndrome from pulmonary embolization of Lipiodol, an iodinated oil commonly used during the procedure. The objective of this report is to describe an atypi...

journal_title：Critical care medicine

authors： Taupin D,Mukherjee V,Nathavitharana R,Green DA,Fridman D

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:Heptafluoropropane is an inert gas commercially used as propellant for inhalers. Since heptafluoropropane can be detected in low concentrations, it could also be used as a tracer gas to measure functional residual capacity and ventilation homogeneity. The aim of the present study was to validate functional re...

journal_title：Critical care medicine

authors： Proquitté H,Kusztrich A,Auwärter V,Pragst F,Wauer RR,Schmalisch G

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVE:Procalcitonin, the precursor peptide of calcitonin, has been shown to be a serum marker of the severity and mortality of several systemic inflammatory response syndromes. This study addressed the correlation of serum procalcitonin with the course of classic (nonexertional) heatstroke. DESIGN:Serum samples we...

journal_title：Critical care medicine

authors： Nylén ES,Al Arifi A,Becker KL,Snider RH Jr,Alzeer A

更新日期：1997-08-01 00:00:00

abstract：OBJECTIVE:To study the impact of a clinical pharmacist in a pediatric intensive care unit. The goals of the study were to determine the type and quantity of patient care interventions recommended by a clinical pharmacist and to specifically examine cost savings (or loss) that resulted from clinical pharmacist recommend...

journal_title：Critical care medicine

authors： Krupicka MI,Bratton SL,Sonnenthal K,Goldstein B

更新日期：2002-04-01 00:00:00

abstract：:Hypersensitivity reactions are defined as immunologically based adverse reactions to chemicals or medicinal agents. These reactions are common in the intensive care unit and can present as a simple, mildly symptomatic rash or as life-threatening anaphylactic reactions. Hypersensitivity reactions have traditionally bee...

journal_title：Critical care medicine

authors： Kanji S,Chant C

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:To compare the impact of two different customization strategies in the performance of the admission Mortality Probability Model II (MPM II0) using formal statistical assessment. DESIGN:Analysis of the database of a multicenter, multinational, prospective cohort study, EURICUS-1, involving 89 intensive care u...

journal_title：Critical care medicine

authors： Moreno R,Apolone G

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVES:To assess the amount of nutrients delivered, prescribed, and required for critically ill patients and to identify the reasons for discrepancies between prescriptions and requirements and between prescriptions and actual delivery of nutrition. DESIGN:Prospective cohort study. SETTING:Twelve-bed medical inte...

journal_title：Critical care medicine

authors： De Jonghe B,Appere-De-Vechi C,Fournier M,Tran B,Merrer J,Melchior JC,Outin H

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the occurrence of complications and patient deteriorations during the air and ground transportation of intubated pediatric patients, performed by a nonphysician-based team under the direction of an intensive care attending physician or fellow. DESIGN:Retrospective chart review. SETTING:A 600-bed...

journal_title：Critical care medicine

authors： Beyer AJ 3rd,Land G,Zaritsky A

更新日期：1992-07-01 00:00:00