Restoration of hormonal action and muscle protein.

abstract：OBJECTIVES:To evaluate the association between length of ICU stay and 1-year mortality for elderly patients who survived to hospital discharge in the United States. DESIGN:Retrospective cohort study of a random sample of Medicare beneficiaries who survived to hospital discharge, with 1- and 3-year follow-up, stratifie...

journal_title：Critical care medicine

authors： Moitra VK,Guerra C,Linde-Zwirble WT,Wunsch H

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVES:In the Acute Respiratory Distress Syndrome Network randomized controlled trial, methylprednisolone treatment was associated with increased return to mechanical ventilation with partial loss of early improvements. We hypothesize a causal relationship between protocol-driven rapid discontinuation of methylpred...

journal_title：Critical care medicine

authors： Meduri GU,Bridges L,Siemieniuk RAC,Kocak M

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVES:To address the association between the 2003 heat wave in Paris (France) and the occurrence of out-of-hospital cardiac arrest. DESIGN:: An analysis of the interventions of the medical mobile intensive care units of the City of Paris for out-of-hospital cardiac arrest and prehospital myocardial infarctions, w...

journal_title：Critical care medicine

authors： Empana JP,Sauval P,Ducimetiere P,Tafflet M,Carli P,Jouven X

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:To describe three female patients of one family with different phenotypes of the same mutation of the ornithine transcarbamylase gene. X-linked inherited ornithine transcarbamylase deficiency is the most frequent urea cycle disorder. Many of the hemizygous males die during the neonatal period. Women, who are ...

journal_title：Critical care medicine

authors： Legras A,Labarthe F,Maillot F,Garrigue MA,Kouatchet A,Ogier de Baulny H

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVES:To determine whether excessive alcohol consumption increases the risk for intensive care unit (ICU)-acquired bacterial infection, especially ventilator-associated pneumonia (VAP), in nontrauma patients. DESIGN:Prospective observational cohort study. SETTING:A 21-bed polyvalent ICU in a university hospital....

journal_title：Critical care medicine

authors： Gacouin A,Legay F,Camus C,Volatron AC,Barbarot N,Donnio PY,Thomas R,Le Tulzo Y

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that the lectin-like domain of tumor necrosis factor, mimicked by the TIP peptide, can improve lung function after unilateral orthotopic lung isotransplantation. Because of a lack of a specific treatment for ischemia reperfusion-mediated lung injury, accompanied by a disrupted barrier i...

journal_title：Critical care medicine

authors： Hamacher J,Stammberger U,Roux J,Kumar S,Yang G,Xiong C,Schmid RA,Fakin RM,Chakraborty T,Hossain HM,Pittet JF,Wendel A,Black SM,Lucas R

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:To describe a case of hepatic subcapsular hematoma causing an acute Budd-Chiari-like syndrome, leading to hepatic compartment syndrome, which combines compression of intrahepatic vessels on CT, acute liver failure, and refractory shock. DESIGN:Case report. SETTING:Surgical ICU of a university teaching hospi...

journal_title：Critical care medicine

authors： Marcaire F,Malavieille F,Pichot-Delahaye V,Floccard B,Rimmelé T

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVES:Carbon monoxide poisoning affects 50,000 per year in the United States alone. Mortality is approximately 3%, and up to 40% of survivors suffer from permanent neurocognitive and affective deficits. Hyperbaric oxygen therapy has shown benefit on reducing the long-term neurologic sequelae of carbon monoxide poi...

journal_title：Critical care medicine

authors： Rose JJ,Nouraie M,Gauthier MC,Pizon AF,Saul MI,Donahoe MP,Gladwin MT

更新日期：2018-07-01 00:00:00

abstract：:Utilizing a well-established porcine model of cardiac arrest, we found that end-tidal CO2 concentration (ETCO2) strikingly decreased to approximately 24% of control levels, immediately after cardiac arrest and before precordial compression. During precordial compression, ETCO2 progressively increased to 46% of control...

journal_title：Critical care medicine

authors： Trevino RP,Bisera J,Weil MH,Rackow EC,Grundler WG

更新日期：1985-11-01 00:00:00

abstract：OBJECTIVES:1) To evaluate the prognostic roles of quantitative CT and pulmonary function tests and 2) to assess the association of dynamic strain and ventilation heterogeneity during unassisted spontaneous breathing with 90-day survival in patients with paraquat poisoning. DESIGN:Prospective study. SETTING:A universi...

journal_title：Critical care medicine

authors： Liu Y,Luo XJ,Li GQ,Wei LQ,Yu X,Li YM

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVES:To evaluate the preload dependence of femoral maximal change in pressure over time (dP/dtmax) during volume expansion in preload dependent and independent critically ill patients. DESIGN:Retrospective database analysis. SETTING:Two adult polyvalent ICUs. PATIENTS:Twenty-five critically ill patients with a...

journal_title：Critical care medicine

authors： Vaquer S,Chemla D,Teboul JL,Ahmad U,Cipriani F,Oliva JC,Ochagavia A,Artigas A,Baigorri F,Monnet X

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVES:Secretoneurin is associated with cardiomyocyte Ca handling and improves risk prediction in patients with acute myocardial dysfunction. Whether secretoneurin improves risk assessment on top of established cardiac biomarkers and European System for Cardiac Operative Risk Evaluation II in patients undergoing ca...

journal_title：Critical care medicine

authors： Brynildsen J,Petäjä L,Myhre PL,Lyngbakken MN,Nygård S,Stridsberg M,Christensen G,Ottesen AH,Pettilä V,Omland T,Røsjø H

更新日期：2019-05-01 00:00:00

abstract：:The determination of minute oxygen consumption (VO2) for metabolic studies on patients using either the Beckman Metabolic Cart (MMC) or the Respiratory Monitoring System (RMS) requires a stable fractional inspired oxygen concentration (FIO2). Measurement of VO2 on mechanically ventilated patients using the Bourns BEAR...

journal_title：Critical care medicine

authors： Browning JA,Linberg SE,Turney SZ,Chodoff P

更新日期：1982-02-01 00:00:00

abstract：OBJECTIVE:To assess whether paralysis alters pulmonary deposition of albuterol delivered by metered dose inhaler and spacer to small animals. DESIGN:A parallel group study of intubated and ventilated rabbits. INTERVENTIONS:Animals in group 1 (n = 7) were paralyzed with intravenous pancuronium, and ventilated at a rat...

journal_title：Critical care medicine

authors： Fok TF,al-Essa M,Monkman S,Dolovich M,Girard L,Coates G,Kirpalani H

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to evaluate the efficacy of perioperative intra-aortic balloon pump use in high-risk cardiac surgery patients. DESIGN:A single-center randomized controlled trial and a meta-analysis of randomized controlled trials. SETTING:Heart Institute of São Paulo University. PATIENTS:High-ri...

journal_title：Critical care medicine

authors： Rocha Ferreira GS,de Almeida JP,Landoni G,Vincent JL,Fominskiy E,Gomes Galas FRB,Gaiotto FA,Dallan LO,Franco RA,Lisboa LA,Palma Dallan LR,Fukushima JT,Rizk SI,Park CL,Strabelli TM,Gelas Lage SH,Camara L,Zeferino S,Jar

更新日期：2018-08-01 00:00:00

abstract：CONTEXT:The results of studies on noninvasive positive pressure ventilation (NPPV) for acute hypoxemic respiratory failure unrelated to cardiogenic pulmonary edema have been inconsistent. OBJECTIVE:To assess the effect of NPPV on the rate of endotracheal intubation, intensive care unit and hospital length of stay, and...

journal_title：Critical care medicine

authors： Keenan SP,Sinuff T,Cook DJ,Hill NS

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to test the hypothesis that cocaine-induced cerebral vasodilation in newborn sheep is mediated via beta-adrenergic receptor activation. DESIGN:The cerebral effects of a single intravenous injection of cocaine (4 mg/kg) given 30 mins after pretreatment with propranolol (1 mg/kg...

journal_title：Critical care medicine

authors： O'Brien TP,Pane MA,Traystman RJ,Gleason CA

更新日期：1999-04-01 00:00:00

abstract：OBJECTIVE:Our aim was to determine the frequency and the clinical and epidemiologic characteristics of sepsis in a hospital-based population in Colombia. DESIGN:Prospective cohort. SETTING:Ten general hospitals in the four main cities of Colombia. PATIENTS:Consecutive patients admitted in emergency rooms, intensive ...

journal_title：Critical care medicine

authors： Rodríguez F,Barrera L,De La Rosa G,Dennis R,Dueñas C,Granados M,Londoño D,Molina F,Ortiz G,Jaimes F

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:To examine the isolated and combined effects of positive end-expiratory pressure (PEEP) and partial liquid ventilation (PLV) on the development of ventilator-induced lung injury in an ovine model. DESIGN:Prospective controlled animal study. SETTING:University-based cardiovascular animal physiology laborator...

journal_title：Critical care medicine

authors： Reickert CA,Rich PB,Crotti S,Mahler SA,Awad SS,Lynch WR,Johnson KJ,Hirschl RB

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVES:Guidelines recommend offering family members of critically ill patients the option to attend interdisciplinary team rounds as a way to improve communication and satisfaction. Uncertainty remains around the benefits and risks. DESIGN:We conducted an observational study to describe family participation in ICU...

journal_title：Critical care medicine

authors： Au SS,Roze des Ordons AL,Parsons Leigh J,Soo A,Guienguere S,Bagshaw SM,Stelfox HT

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:Inotropic and vasopressor drugs are routinely used in critically ill patients to maintain adequate blood pressure and cardiac output in patients with cardiogenic shock although potentially at the expense of increasing myocardial oxygen demand. Pacing optimization has been demonstrated as effective in reducing...

journal_title：Critical care medicine

authors： Tavazzi G,Kontogeorgis A,Bergsland NP,Price S

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:To compare prone positioning and continuous rotational therapy with respect to oxygenation and hemodynamics in patients suffering from adult respiratory distress syndrome (ARDS). DESIGN:Randomized, prospective pilot study. SETTING:Intensive care unit at a university hospital. PATIENTS:Twenty-six mechanical...

journal_title：Critical care medicine

authors： Staudinger T,Kofler J,Müllner M,Locker GJ,Laczika K,Knapp S,Losert H,Frass M

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:Antioxidant therapy has shown some promise in critical care medicine in which glutathione depletion and heart failure are often seen in critically ill patients. This study was designed to examine the impact of glutathione depletion and the free radical scavenger, metallothionein (MT), on cardiac function. DE...

journal_title：Critical care medicine

authors： Ren J,Privratsky JR,Yang X,Dong F,Carlson EC

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:To examine variations in case-mix, structure, resource use, and outcome performance among teaching and nonteaching intensive care units (ICU). DESIGN:Prospective inception cohort study. PATIENTS:A consecutive sample of 15,297 patients at 35 hospitals, which compared 8,269 patients admitted to 20 teaching IC...

journal_title：Critical care medicine

authors： Zimmerman JE,Shortell SM,Knaus WA,Rousseau DM,Wagner DP,Gillies RR,Draper EA,Devers K

更新日期：1993-10-01 00:00:00

abstract：OBJECTIVES:To describe the unique perspective of pediatric intensivists caring for critically ill adults during the coronavirus disease 2019 pandemic. DESIGN:Observational study. SETTING:Academic medical center in New York City. PATIENTS:Coronavirus disease 2019 positive adults requiring admission to an ICU. INTERV...

journal_title：Critical care medicine

authors： Joyce CL,Howell JD,Toal M,Wasserman E,Finkelstein RA,Traube C,Killinger JS,Joashi U,Greenwald BM,Nellis ME

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:Pulmonary edema is a serious condition following brain injury of diverse etiologies, including large hemispheric infarctions. We have previously shown that treatment with hypertonic saline attenuates cerebral edema associated with experimental ischemic stroke. In a well-characterized animal model of large isc...

journal_title：Critical care medicine

authors： Toung TJ,Chang Y,Lin J,Bhardwaj A

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:Tea has been around for centuries, and its medicinal properties have been purported in the literature but never fully confirmed. Interleukin-8 is a principle neutrophil chemoattractant and activator in humans. We determined the effects of theaflavin, a black tea-derived polyphenol, on tumor necrosis factor-al...

journal_title：Critical care medicine

authors： Aneja R,Odoms K,Denenberg AG,Wong HR

更新日期：2004-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the safety and diagnostic yield of transbronchial biopsy performed in mechanically ventilated patients. DESIGN:Retrospective, cohort analysis. SETTING:A university-affiliated teaching hospital. PATIENTS:Seventy-one consecutive, mechanically ventilated patients requiring lung tissue examination....

journal_title：Critical care medicine

authors： O'Brien JD,Ettinger NA,Shevlin D,Kollef MH

更新日期：1997-03-01 00:00:00

abstract：OBJECTIVE:Sepsis and acute lung injury continue to be major causes of morbidity and mortality worldwide despite advances in our understanding of pathophysiology and the discovery of new management strategies. Recent investigations show that stem cells may be beneficial as prognostic biomarkers and novel therapeutic str...

journal_title：Critical care medicine

authors： Cribbs SK,Matthay MA,Martin GS

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVE:To compare urea nitrogen removal by continuous hemodiafiltration vs. functional native kidneys in critically ill, septic patients receiving > 2 g of amino acids/kg body weight per day. DESIGN:Prospective, comparative, unblinded study. SETTING:Trauma critical care units of a Level I adult trauma hospital. P...

journal_title：Critical care medicine

authors： Frankenfield DC,Reynolds HN,Wiles CE 3rd,Badellino MM,Siegel JH

更新日期：1994-03-01 00:00:00