Changes in the brain monoamine metabolism in acute liver failure produced by ischemia-reperfusion injury in rats.

abstract：:Clonidine may be a source of serious toxicity when ingested by toddlers. We describe 11 cases of clonidine ingestion by toddlers (mean dose 0.15 mg/kg; range 0.01 to 0.57). The source of the clonidine was a grand-parent in six of 11 cases. Symptoms included altered level of consciousness (n = 11), miosis (n = 5), brad...

journal_title：Critical care medicine

authors： Fiser DH,Moss MM,Walker W

更新日期：1990-10-01 00:00:00

abstract：OBJECTIVE:To quantify the therapeutic efficacy of loop diuretics in acute renal failure using Bayesian evidence synthesis, because despite widespread use, the role of diuretics is controversial. DATA SOURCE:Randomized controlled trials or nonrandomized studies, 1966 to January 2007, identified from MEDLINE and EMBASE ...

journal_title：Critical care medicine

authors： Sampath S,Moran JL,Graham PL,Rockliff S,Bersten AD,Abrams KR

更新日期：2007-11-01 00:00:00

abstract：:The aim of this study was to assess prospectively the variations of serum phosphorus concentration (P) after onset of mechanical ventilation (MV) in patients with chronic obstructive pulmonary disease (COPD) and acute respiratory acidosis. In 14 COPD patients, we measured P, PaCO2, and pH, immediately before MV (H0), ...

journal_title：Critical care medicine

authors： Laaban JP,Grateau G,Psychoyos I,Laromiguière M,Vuong TK,Rochemaure J

更新日期：1989-11-01 00:00:00

abstract：:To further define cardiovascular abnormalities in patients with septic shock, serial conventional hemodynamic measurements combined with two-dimensional echocardiographic studies were performed at the bedside in 21 patients admitted for an acute episode of sepsis-related circulatory failure. Measurements obtained duri...

journal_title：Critical care medicine

authors： Jardin F,Brun-Ney D,Auvert B,Beauchet A,Bourdarias JP

更新日期：1990-10-01 00:00:00

abstract：OBJECTIVE:To review current knowledge about cell-free hemoglobin solutions. DATA SOURCES:All studies involving cell-free hemoglobin were retrieved from a computerized MEDLINE search from 1980 to 1998. We also reviewed the reference lists of all available review articles and primary studies to identify references not f...

journal_title：Critical care medicine

authors： Creteur J,Sibbald W,Vincent JL

更新日期：2000-08-01 00:00:00

abstract：OBJECTIVE:To compare prone positioning and continuous rotational therapy with respect to oxygenation and hemodynamics in patients suffering from adult respiratory distress syndrome (ARDS). DESIGN:Randomized, prospective pilot study. SETTING:Intensive care unit at a university hospital. PATIENTS:Twenty-six mechanical...

journal_title：Critical care medicine

authors： Staudinger T,Kofler J,Müllner M,Locker GJ,Laczika K,Knapp S,Losert H,Frass M

更新日期：2001-01-01 00:00:00

abstract：:This report documents the validity of clinical measurements of oxygen consumption (VO2) and carbon dioxide production (VCO2) made with a new metabolic gas monitor (MGM) suitable for use in critically ill patients receiving mechanical ventilatory support. Paired samples of inspired and expired gases were obtained, and ...

journal_title：Critical care medicine

authors： Nelson LD,Anderson HB,Garcia H

更新日期：1987-10-01 00:00:00

abstract：OBJECTIVES:To confirm early, marked decrease in plasma selenium concentrations in patients admitted to a surgical and medical intensive care unit (ICU), and to study this decrease according to the presence or absence of systemic inflammatory response syndrome (SIRS), sepsis, or direct ischemia-reperfusion. DESIGN:Pros...

journal_title：Critical care medicine

authors： Forceville X,Vitoux D,Gauzit R,Combes A,Lahilaire P,Chappuis P

更新日期：1998-09-01 00:00:00

abstract：:To achieve normocarbia during conventional mechanical ventilation, ventilator settings are determined initially on the basis of body weight. The best ventilator settings for CO2 elimination during high-frequency jet ventilation (HFJV) have not been so clearly defined. A recent study has suggested that eucarbia will be...

journal_title：Critical care medicine

authors： Bayly R,Sladen A,Tyler IL,Echegaray RF,Klain M,Guntupalli K

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVE:To report a case of fatal hyperkalemia owing to succinylcholine administration in a patient with mucositis secondary to chemotherapy. DESIGN:Case report. SETTING:Adult intensive care unit (ICU) at Dartmouth-Hitchcock Medical Center. PATIENTS:One patient with mucositis secondary to chemotherapy. MEASUREMEN...

journal_title：Critical care medicine

authors： Al-Khafaji AH,Dewhirst WE,Cornell CJ Jr,Quill TJ

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVE:To compare and evaluate the potential benefit of two different anticoagulation regimens during endotoxemia in an ovine model. DESIGN:Animal prospective randomized and controlled study following preliminary dose-range study conforming with the Guide for the Care and Use of Laboratory Animals as promulgated by...

journal_title：Critical care medicine

authors： Schiffer ER,Reber G,De Moerloose P,Morel DR

更新日期：2002-12-01 00:00:00

abstract：:This review focuses on the effects of restoring hormonal levels and/or influence on muscle protein metabolism in the stressed state. We have highlighted our clinical experience in the administration of anabolic and anticatabolic agents in stressed clinical populations, primarily adult and pediatric burn injury, as wel...

journal_title：Critical care medicine

authors： Ferrando AA,Wolfe RR

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVE:To determine the occurrence rate of complications and mortality in patients with severe asthma requiring endotracheal intubation and mechanical ventilation. DESIGN:Retrospective review of medical records from September 1982 to July 1988. SETTING:Urban, teaching hospital serving primarily indigent patients. ...

journal_title：Critical care medicine

authors： Zimmerman JL,Dellinger RP,Shah AN,Taylor RW

更新日期：1993-11-01 00:00:00

abstract：OBJECTIVE:To determine the limits of agreement between the cardiac output and volumetric data estimated by impedance cardiography with the cardiac output determined by thermodilution and the left ventricular ejection fraction and end-diastolic volume estimated from left ventriculography. DESIGN:A prospective study. S...

journal_title：Critical care medicine

authors： Marik PE,Pendelton JE,Smith R

更新日期：1997-09-01 00:00:00

abstract：:Laboratory evaluation and use of the Engström metabolic computer (EMC) in a clinical setting are described. The accuracy of the EMC was tested using an inert gas dilution technique. Mean errors in oxygen consumption (VO2) and CO2 production compared with predicted values were less than 2% of predicted, and generally l...

journal_title：Critical care medicine

authors： Regan CJ,Snowdon SL,Campbell IT

更新日期：1990-08-01 00:00:00

abstract：OBJECTIVE:To determine the ability of somatosensory evoked potentials (SEP) compared with clinical findings to monitor and predict recovery in patients suffering from closed head injury with predominantly diffuse axonal injury (DAI). DESIGN:Prospective cohort study. SETTING:Neurologic intensive care unit (ICU) of a u...

journal_title：Critical care medicine

authors： Claassen J,Hansen HC

更新日期：2001-03-01 00:00:00

abstract：OBJECTIVES:Our primary goal was to evaluate the impact on in-hospital mortality rate of adequate empirical antibiotic therapy, after controlling for confounding variables, in a cohort of patients admitted to the intensive care unit (ICU) with sepsis. The impact of adequate empirical antibiotic therapy on early (<3 days...

journal_title：Critical care medicine

authors： Garnacho-Montero J,Garcia-Garmendia JL,Barrero-Almodovar A,Jimenez-Jimenez FJ,Perez-Paredes C,Ortiz-Leyba C

更新日期：2003-12-01 00:00:00

abstract：:A system of instrumentation for continuous measurement of oxygen consumption (VO2), carbon dioxide production (VCO2) and minute ventilation (V1) in human newborns on assisted ventilation is described. VO2 and VCO2 are measured by open-circuit indirect calorimetry utilizing a Servomex OA 184 differential paramagnetic o...

journal_title：Critical care medicine

authors： Schulze K,Stefanski M,Masterson J,James LS

更新日期：1983-11-01 00:00:00

abstract：OBJECTIVE:Life-threatening conditions cause severe changes in the organization and conformation of macromolecules, creating urgent requirements for protein repair to ensure survival. As molecular chaperones, heat shock proteins (HSP) that have specialized functions in protein folding are now well established to restore...

journal_title：Critical care medicine

authors： Christians ES,Yan LJ,Benjamin IJ

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:To determine prevalence, risk factors, and outcome of thrombocytopenia in medical intensive care patients. DESIGN:Prospective observational study. SETTING:The 12-bed medical intensive care unit of a university hospital. PATIENTS:All consecutively admitted patients with normal platelet count at admission an...

journal_title：Critical care medicine

authors： Strauss R,Wehler M,Mehler K,Kreutzer D,Koebnick C,Hahn EG

更新日期：2002-08-01 00:00:00

abstract：:The educational objectives in use in our Pediatric ICU are described. These have importance for educational programs in critical care medicine, in particular, where patient care needs can easily overwhelm educational needs. It is important not to overlook our role as teachers in the development of proper attitudes and...

journal_title：Critical care medicine

authors： Kravath RE

更新日期：1977-05-01 00:00:00

abstract：OBJECTIVE:To determine whether blood lactate, base deficit, or oxygen-derived hemodynamic variables correlate with morbidity and mortality rates in a clinically-relevant LD50 model of penetrating trauma. DESIGN:Prospective, controlled study. SETTING:University research laboratory. SUBJECTS:Anesthetized, mechanically...

journal_title：Critical care medicine

authors： Moomey CB Jr,Melton SM,Croce MA,Fabian TC,Proctor KG

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVE:To determine whether mechanical ventilation using high tidal volume is associated with nonpulmonary organ dysfunction that can be attenuated by dexamethasone. DESIGN:Prospective randomized animal intervention study. SETTING:Animal care facility in a university hospital. SUBJECTS:Sedated and tracheostomized...

journal_title：Critical care medicine

authors： Nin N,Peñuelas O,de Paula M,Lorente JA,Fernández-Segoviano P,Esteban A

更新日期：2006-04-01 00:00:00

abstract：OBJECTIVE:To determine the effect that acute physiologic derangements have on outcome after subarachnoid hemorrhage (SAH) and to design a composite score summarizing these abnormalities. DESIGN:Prospective observational study. SETTING:Neuroscience intensive care unit in a tertiary care academic center. PATIENTS:Cons...

journal_title：Critical care medicine

authors： Claassen J,Vu A,Kreiter KT,Kowalski RG,Du EY,Ostapkovich N,Fitzsimmons BF,Connolly ES,Mayer SA

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVE:To determine a) if the admission osmole gap, the difference between osmolality and osmolarity, is the same in the neurologic-neurosurgical intensive care unit (NNICU) population as in healthy controls; b) which of 11 osmole gap formulas, or osmolality, correlates best with mannitol serum concentrations; c) wh...

journal_title：Critical care medicine

authors： García-Morales EJ,Cariappa R,Parvin CA,Scott MG,Diringer MN

更新日期：2004-04-01 00:00:00

abstract：OBJECTIVE:The mortality of critically ill patients associated with intestinal ischemia/reperfusion remains very high, which results from multiorgan dysfunction or failure due to intestinal injury induced by intestinal ischemia/reperfusion. This study was carried out to investigate whether intestinal ischemia/reperfusio...

journal_title：Critical care medicine

authors： Zhou J,Huang WQ,Li C,Wu GY,Li YS,Wen SH,Lei WL,Liu KX

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:Patients with severe sepsis have high mortality that is improved by timely, often expensive, treatments. Patients without insurance are more likely to delay seeking care; they may also receive less intense care. DESIGN:We performed a retrospective analysis of administrative database-Healthcare Costs and Util...

journal_title：Critical care medicine

authors： Kumar G,Taneja A,Majumdar T,Jacobs ER,Whittle J,Nanchal R,Milwaukee Initiative in Critical Care Outcomes Research (MICCOR) Group of Investigators.

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVES:The mortality outcome of mechanical ventilation, a key intervention in the critically ill, has been variously reported to be determined by intensive care patient volume. We determined the volume-(mortality)-outcome relationship of mechanically ventilated patients whose records were contributed to the Austral...

journal_title：Critical care medicine

authors： Moran JL,Solomon PJ,ANZICS Centre for Outcome and Resource Evaluation of the Australian and New Zealand Intensive Care Society.

更新日期：2012-03-01 00:00:00

abstract：:Chest physiotherapy (CPT) is used frequently in the ICU, but there is little available information that quantitates its effect on cardiac or respiratory function. Nineteen mechanically ventilated patients with post-traumatic respiratory failure were studied before, immediately after, and 2 h after CPT was used to mana...

journal_title：Critical care medicine

authors： Mackenzie CF,Shin B

更新日期：1985-06-01 00:00:00

abstract：OBJECTIVE:To determine the effects of accidental injury of varying severity on interleukin (IL)-1 alpha, IL-6, IL-8, tumor necrosis factor-alpha (TNF-alpha), and endotoxin release. DESIGN:Prospective, multi-unit, longitudinal study. SETTING:Emergency Departments and intensive care units of two university hospitals. ...

journal_title：Critical care medicine

authors： Hoch RC,Rodriguez R,Manning T,Bishop M,Mead P,Shoemaker WC,Abraham E

更新日期：1993-06-01 00:00:00