Abstract:
:According to our present knowledge hypometabolism and hypothermia in uremia are most probably due to direct actions of toxic substances at the cellular level. A cardiovascular etiology seems less possible. A similar reduction of oxygen consumption as observed in uremia can be produced by 5 mg/kg body wt. indole i.p. Acetoine, m- and p-cresol, methylguanidine and putrescine do not reduce oxygen consumption even at tenfold higher doses. Some combinations of these substances, however, are effective when given only 10 mg/kg body wt. each. The effects in vivo cannot be reproduced by employing in vitro systems.
journal_name
Adv Exp Med Bioljournal_title
Advances in experimental medicine and biologyauthors
Hohenegger M,Echsel H,Vermes M,Raneburger Hdoi
10.1007/978-1-4684-8240-9_13subject
Has Abstractpub_date
1987-01-01 00:00:00pages
99-104eissn
0065-2598issn
2214-8019journal_volume
212pub_type
杂志文章abstract::Honokiol (C18H18O2) is a biphenolic natural product isolated from the bark and leaves of Magnolia plant spp. During the last decade or more, honokiol has been extensively studied for its beneficial effect against several diseases. Investigations have demonstrated that honokiol possesses anti-carcinogenic, anti-inflamm...
journal_title:Advances in experimental medicine and biology
pub_type: 杂志文章,评审
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journal_title:Advances in experimental medicine and biology
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journal_title:Advances in experimental medicine and biology
pub_type: 杂志文章,评审
doi:10.1007/978-1-4615-1899-0_79
更新日期:1995-01-01 00:00:00
abstract::This study surveyed that the relationship between the frequencies of intake of taurine-contained nutritional drinks (TCND), and lifestyle and the purposes of intake it. The study was conducted a cross-sectional survey using 265 people (203 male, 62 female) aged 18-64 worked in two companies in Mie Prefecture, Japan be...
journal_title:Advances in experimental medicine and biology
pub_type: 杂志文章
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更新日期:2019-01-01 00:00:00
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journal_title:Advances in experimental medicine and biology
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journal_title:Advances in experimental medicine and biology
pub_type: 杂志文章,评审
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更新日期:2014-01-01 00:00:00
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journal_title:Advances in experimental medicine and biology
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
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journal_title:Advances in experimental medicine and biology
pub_type: 杂志文章
doi:10.1007/978-3-319-02970-2_6
更新日期:2014-01-01 00:00:00
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journal_title:Advances in experimental medicine and biology
pub_type: 杂志文章,评审
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更新日期:2016-01-01 00:00:00
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journal_title:Advances in experimental medicine and biology
pub_type: 杂志文章
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更新日期:2016-01-01 00:00:00
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journal_title:Advances in experimental medicine and biology
pub_type: 临床试验,杂志文章
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更新日期:2010-01-01 00:00:00
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journal_title:Advances in experimental medicine and biology
pub_type: 杂志文章
doi:10.1007/978-1-4899-5037-6_16
更新日期:1988-01-01 00:00:00
abstract::Two species of T-kininogen which release T-kinin (Ile-Ser-bradykinin) have been purified from plasma of rats treated with Freund's complete adjuvant. The molecular weight was estimated to be 69,000 for either T-kininogen I and II by SDS-polyacrylamide gel electrophoresis. Trypsin released one mole of T-kinin from one ...
journal_title:Advances in experimental medicine and biology
pub_type: 杂志文章
doi:10.1007/978-1-4684-5143-6_10
更新日期:1986-01-01 00:00:00
abstract::Taurine, an endogenous amino sulfonic acid, exhibits numerous neuropsychopharmacological activities. Previous studies in our laboratory have shown that it is an effective anti-cataleptic and neuro-protective agent. Current investigations show that acute or chronic administration of psychotropic drug cocaine may increa...
journal_title:Advances in experimental medicine and biology
pub_type: 杂志文章
doi:10.1007/978-1-4614-6130-2_1
更新日期:2013-01-01 00:00:00
abstract::Alterations in structural and biochemical properties of muscles that underlie physiological parameters of contractile force, speed and fatigability are described under conditions of 1) overuse: imposed electrical stimulation, natural exercise and functional overload; 2) reinnervation of denervated muscles; and 3) unde...
journal_title:Advances in experimental medicine and biology
pub_type: 杂志文章,评审
doi:
更新日期:1995-01-01 00:00:00
abstract::Chemotherapy is one of the frontline treatments for cancer patients, but the toxic side effects limit its effectiveness and potential. The goal of drug delivery is to reduce these side effects by encapsulating the drugs in a carrier which prevents release and can circulate throughout the body causing minimal damage to...
journal_title:Advances in experimental medicine and biology
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doi:10.1007/978-94-007-2555-3_14
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abstract::Sonodynamic therapy (SDT) represents an emerging approach that offers the possibility of non-invasively eradicating solid tumors in a site-directed manner. It involves the sensitization of target tissues with a non-toxic sensitizing chemical agent and subsequent exposure of the sensitized tissues to relatively low-int...
journal_title:Advances in experimental medicine and biology
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abstract::Alpha E beta 7 (αEβ7) is an α-I domain-containing integrin that is highly expressed by a variety of leukocyte populations at mucosal sites including intraepithelial T cells, dendritic cells, mast cells, and T regulatory cells (Treg). Expression depends largely or solely on transforming growth factor beta (TGF-β) isofo...
journal_title:Advances in experimental medicine and biology
pub_type: 杂志文章,评审
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更新日期:2014-01-01 00:00:00
abstract::All results presented here would indicate that serotonin plays an important role in animal behavior such as locomotor depression and that, taking into consideration the effects of antidepressants on 5-HT receptor activity as well as recent biochemical findings of human depression, some forms of human depression could ...
journal_title:Advances in experimental medicine and biology
pub_type: 杂志文章
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更新日期:1981-01-01 00:00:00
abstract::Mortality from plague is high if not treated with the proper antibiotics within 18-24 hours after onset of symptoms. The process of antibiotic susceptibility determination of Yersinia pestis isolated from blood samples may extend from 4 to more than 7 days, since the in vitro growth is very slow. To accelerate this pr...
journal_title:Advances in experimental medicine and biology
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更新日期:2007-01-01 00:00:00
abstract::circRNAs have emerged as one of the key regulators in many cellular mechanisms and pathogenesis of diseases. However, with the limited knowledge and current technologies for circRNA investigations, there are several challenges that need to be addressed for. These include challenges in understanding the regulation of c...
journal_title:Advances in experimental medicine and biology
pub_type: 杂志文章,评审
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更新日期:2018-01-01 00:00:00
abstract::We describe a new monoclonal antibody No. 204 (mcAb 204) which recognized a family of four polypeptides, consisting of a 27kD, a 24/23kD double band and a 19kD protein present within PEDV infected cell lysates. These proteins were identified by immunoprecipitation as well as by staining of immunoblots. In infected Ver...
journal_title:Advances in experimental medicine and biology
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更新日期:1993-01-01 00:00:00
abstract::Optical methods assess different types of light tissue interactions such as light absorption, fluorescence, phosphoresence, scattering, and Doppler shift. In this article, it is reviewed how these different types of light-tissue interactions can be measured and how these measurements can be related to brain function. ...
journal_title:Advances in experimental medicine and biology
pub_type: 杂志文章,评审
doi:
更新日期:1997-01-01 00:00:00
abstract::Frontotemporal dementia (FTD) is a neurodegenerative disease with high heritability. Almost half of all familial cases are caused by mutations in one of the three genes MAPT, GRN and C9orf72. Even though major advances in FTD research have been achieved during the last decades, it is not yet fully understood how mutat...
journal_title:Advances in experimental medicine and biology
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更新日期:2021-01-01 00:00:00
abstract::Non-coding RNAs (ncRNAs) are untranslated RNA molecules that function to regulate the expression of numerous genes and associated biochemical pathways and cellular functions. NcRNAs include small interfering RNAs (siRNAs), microRNAs (miRNAs), PIWI-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs) and long non-...
journal_title:Advances in experimental medicine and biology
pub_type: 杂志文章,评审
doi:10.1007/978-94-017-7417-8_7
更新日期:2016-01-01 00:00:00
abstract::Taurine is traditionally used to treat Down Syndrome (DS); however, the actual foundation for this treatment is not well understood. DS patients suffer from disturbance of the proteostasis network (PN) due to aberrant calcium signaling, which eventually causes endoplasmic reticulum stress (ERS). Taurine has been sugge...
journal_title:Advances in experimental medicine and biology
pub_type: 杂志文章
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更新日期:2019-01-01 00:00:00
abstract::Bryophytes are small land plants that have many morphological and physiological features different from vascular plants. With distinct water relations of bryophytes, many bryophyte species exhibit high degrees of tolerance to freezing and desiccation. The tolerance is sustained by the constitutive repair mechanism and...
journal_title:Advances in experimental medicine and biology
pub_type: 杂志文章,评审
doi:10.1007/978-981-13-1244-1_10
更新日期:2018-01-01 00:00:00
abstract::Permethylated N-trifluoroacetyl hexosamine containing oligosaccharide alditols are favorable for analysis by mass spectrometry. Electron impact and fast atom bombardment mass spectra of these derivatives are characterized by strong primary and secondary fragments in which a positive charge is localized on the N-triflu...
journal_title:Advances in experimental medicine and biology
pub_type: 杂志文章
doi:10.1007/978-1-4613-1663-3_35
更新日期:1988-01-01 00:00:00