Huntingtin interacting proteins 14 and 14-like are required for chorioallantoic fusion during early placental development.

abstract：:Exocytosis of cortical granules in mouse eggs is required to produce the zona pellucida block to polyspermy. In this study, we examined the role of microfilaments and microtubules in the regulation of cortical granule movement toward the cortex during oocyte maturation and anchoring of cortical granules in the cortex....

journal_title：Developmental biology

authors： Connors SA,Kanatsu-Shinohara M,Schultz RM,Kopf GS

更新日期：1998-08-01 00:00:00

abstract：:In a previous study (K.-I. Sato et al., 1999, Dev. Biol. 209, 308-320), we presented evidence that a Src-related protein-tyrosine kinase (PTK), named Xyk, may act upstream of the calcium release in fertilization of the Xenopus egg. In the present study, we examined whether PTK activation of phospholipase Cgamma (PLCga...

journal_title：Developmental biology

authors： Sato K,Tokmakov AA,Iwasaki T,Fukami Y

更新日期：2000-08-15 00:00:00

abstract：:Urodeles begin gastrulation with much of their presumptive mesoderm in the superficial cell layer, all of which must move into the deep layers during development. We studied the morphogenesis of superficial mesoderm in the urodeles Ambystoma maculatum, Ambystoma mexicanum, and Taricha granulosa. In all three species, ...

journal_title：Developmental biology

authors： Shook DR,Majer C,Keller R

更新日期：2002-08-15 00:00:00

abstract：:We have analyzed several aspects of the development of flies carrying mutations at the Glued locus. Optic lobe abnormalities in individuals heterozygous for the original Glued allele were previously shown to result from an action of this mutation in the retinula cells. We have estimated when the functioning of this ge...

journal_title：Developmental biology

authors： Harte PJ,Kankel DR

更新日期：1983-09-01 00:00:00

abstract：:Actin-related protein 5 (ARP5) is a conserved subunit of the INO80 chromatin-remodeling complex in yeast and mammals. We have characterized the expression and subcellular distribution of Arabidopsis thaliana ARP5 and explored its role in the epigenetic control of multicellular development and DNA repair. ARP5-specific...

journal_title：Developmental biology

authors： Kandasamy MK,McKinney EC,Deal RB,Smith AP,Meagher RB

更新日期：2009-11-01 00:00:00

abstract：:The clonal multipotential RCJ 3.1 cell line, which gives rise to myotubes, adipocytes, chondrocytes, and osteoblasts, contains different progenitor subpopulations. By limiting dilution analysis, of 296 single colonies identified, approximately 20% contained a single recognizable cell type, approximately 10% contained ...

journal_title：Developmental biology

authors： Grigoriadis AE,Heersche JN,Aubin JE

更新日期：1990-12-01 00:00:00

abstract：:In the marine bivalve Hiatella flaccida, full-grown oocytes in ovaries are arrested at the first prophase (prophase-I) of meiosis, whereas spawned oocytes have reinitiated meiosis from prophase-I and are again arrested at the first metaphase (metaphase-I). The neurohormone serotonin (5-hydroxytryptamine, 5-HT) was abl...

journal_title：Developmental biology

authors： Deguchi R,Osanai K

更新日期：1995-10-01 00:00:00

abstract：:The mammalian prostate arises from the urogenital sinus and few factors have been identified to be important in the early stages of prostate development. In this study we show that the transcription factor Sox9 is expressed in the epithelia of all mouse prostatic lobes from the initial stages of their development. We ...

journal_title：Developmental biology

authors： Thomsen MK,Butler CM,Shen MM,Swain A

更新日期：2008-04-15 00:00:00

abstract：:C. elegans ahr-1 is orthologous to the mammalian aryl hydrocarbon receptor, and it functions as a transcription factor to regulate the development of certain neurons. Here, we describe the role of ahr-1 in a specific behavior: the aggregation of C. elegans on lawns of bacterial food. This behavior is modulated by nutr...

journal_title：Developmental biology

authors： Qin H,Zhai Z,Powell-Coffman JA

更新日期：2006-10-15 00:00:00

abstract：:The nuclear receptor SpCOUP-TF is the highly conserved sea urchin homologue of the COUP family of transcription factors. Previous results from our laboratory demonstrated that SpCOUP-TF transcripts are localized in the egg and asymmetrically distributed in the early embryonic blastomeres (A. Vlahou et al., 1996, Devel...

journal_title：Developmental biology

authors： Vlahou A,Flytzanis CN

更新日期：2000-02-15 00:00:00

abstract：:Thyroid hormone (TH) induces dramatic skeletal and tissue remodeling of the anuran head and body at metamorphosis. The expression pattern of TH up-regulated genes has been correlated with tissues that either grow or resorb at metamorphosis. Whereas the expression of the thyroid hormone receptors in Xenopus laevis tadp...

journal_title：Developmental biology

authors： Berry DL,Rose CS,Remo BF,Brown DD

更新日期：1998-11-01 00:00:00

abstract：:Previous studies have shown that cultured Schwann cells secrete platelet-derived growth factor (PDGF) and express PDGF receptors which transmit a mitogenic response particularly when their levels are upregulated by elevation of intracellular cAMP. In this study the expression of PDGF and PDGF alpha- and beta-receptors...

journal_title：Developmental biology

authors： Eccleston PA,Funa K,Heldin CH

更新日期：1993-02-01 00:00:00

abstract：:The experimental manipulation of early embryologic events, resulting in the misexpression of the homeobox transcription factor pitx2, is associated with subsequent defects of laterality in a number of vertebrate systems. To clarify the role of one pitx2 isoform, pitx2c, in determining the left-right axis of amphibian ...

journal_title：Developmental biology

authors： Dagle JM,Sabel JL,Littig JL,Sutherland LB,Kolker SJ,Weeks DL

更新日期：2003-10-15 00:00:00

abstract：:The primary lung bud originates from the foregut and develops into the bronchial tree by repetitive branching and outgrowing of the airway. The Sry related HMG box protein Sox2 is expressed in a cyclic manner during initiation and branching morphogenesis of the lung. It is highly expressed in non-branching regions and...

journal_title：Developmental biology

authors： Gontan C,de Munck A,Vermeij M,Grosveld F,Tibboel D,Rottier R

更新日期：2008-05-01 00:00:00

abstract：:Although mitogen-activated protein kinase (MAPK) is a well-known cell cycle regulator, emerging studies have also implicated its activity in the regulation of intracellular calcium concentration ([Ca2+](i)) and secretion. Those studies raise the hypothesis that MAPK activity during oocyte maturation and early fertiliz...

journal_title：Developmental biology

authors： Matson S,Ducibella T

更新日期：2007-06-15 00:00:00

abstract：:Rho GTPases control signal transduction pathways that link cell surface receptors to a variety of intracellular responses. They are best known as regulators of the actin cytoskeleton, but in addition they control cell polarity, gene expression, microtubule dynamics and vesicular trafficking. Through these diverse func...

journal_title：Developmental biology

authors： Raftopoulou M,Hall A

更新日期：2004-01-01 00:00:00

abstract：:Primary mesenchyme cell migration in the sea urchin embryo is inhibited by sulfate deprivation and exposure to exogenous beta-D-xylosides, two treatments known to disrupt proteoglycan synthesis. We show that in the developing sea urchin, exogenous xyloside affects the synthesis by the primary mesenchyme cells of a ver...

journal_title：Developmental biology

authors： Lane MC,Solursh M

更新日期：1991-02-01 00:00:00

abstract：:Repair and regeneration of adult skeletal muscle are mediated by satellite cells. In healthy muscle these rare mononucleate muscle precursor cells are mitotically quiescent. Upon muscle injury or degeneration, members of this self-renewing pool are activated to proliferate and then differentiate. Here we analyzed in s...

journal_title：Developmental biology

authors： Cornelison DD,Wold BJ

更新日期：1997-11-15 00:00:00

abstract：:The zebrafish hedgehog (hh) family members tiggy-winkle hedgehog (twhh) and sonic hedgehog (shh) are involved in patterning the ventral CNS and proximal eye. Using a dominant negative protein kinase A regulatory subunit mutant, we show that these hh activities are mediated by protein kinase A. The effects of dominant ...

journal_title：Developmental biology

authors： Ungar AR,Moon RT

更新日期：1996-08-25 00:00:00

abstract：:We determined expression and function of a cell membrane protein in the developing chick retinotectal system identified by a monoclonal antibody (mAb 4H5) and the corresponding antiserum. Our data revealed that the protein shares a series of properties, including the N-terminal amino acid sequence, with a cell adhesio...

journal_title：Developmental biology

authors： Pollerberg GE,Mack TG

更新日期：1994-10-01 00:00:00

abstract：:Epigenetic gene control is involved in mechanisms of development. Little is known about the cooperation of nuclear and chromatin events in programmed differentiation from mouse embryonic stem cells (ESC). To address this, Oct3/4-positive ESC and differentiated progenies, Sox1-positive neural precursor cells (NPC) and ...

journal_title：Developmental biology

authors： Aoto T,Saitoh N,Ichimura T,Niwa H,Nakao M

更新日期：2006-10-15 00:00:00

abstract：:Murine ovarian folliculogenesis commences after birth involving oocyte growth, somatic cell differentiation and structural remodeling of follicle stromal boundaries. The extracellular metalloproteinase ADAMTS-1 has activity against proteoglycans and collagen and is produced by the granulosa cells of ovarian follicles....

journal_title：Developmental biology

authors： Brown HM,Dunning KR,Robker RL,Pritchard M,Russell DL

更新日期：2006-12-15 00:00:00

abstract：:Type II collagen is a major component of hyaline cartilage, and has been suggested to be causally involved in promoting chondrogenesis during embryonic development. In the present study we have performed an immunohistochemical analysis of the distribution of type II collagen during several early stages of embryonic ch...

journal_title：Developmental biology

authors： Kosher RA,Solursh M

更新日期：1989-02-01 00:00:00

abstract：:Stimulation of epithelial cell cycling by the neuropeptide head activator was analyzed in Hydra magnipapillata and compared with the action of head activator on bud formation and tentacle formation during head regeneration. The results obtained indicate that head activator treatment stimulates epithelial cell division...

journal_title：Developmental biology

authors： Hobmayer B,Holstein TW,David CN

更新日期：1997-03-01 00:00:00

abstract：:The organizer is an essential signaling center required for axial formation during vertebrate embryonic development. In the basal chordate amphioxus, the dorsal blastopore lip of the gastrula has been proposed to be homologous to the vertebrate organizer. Lefty is one of the first genes to be expressed in the organize...

journal_title：Developmental biology

authors： Zhang H,Chen S,Shang C,Wu X,Wang Y,Li G

更新日期：2019-12-01 00:00:00

abstract：:Mitogen-activated protein kinases (MAPKs) are important regulators of many cellular processes. In mammalian testes, these kinases are involved in controlling cell division, differentiation, survival and death, and are therefore critical to spermatogenesis. Recent studies have also illustrated their involvement in junc...

journal_title：Developmental biology

authors： Wong CH,Cheng CY

更新日期：2005-10-01 00:00:00

abstract：:We have investigated oocyte development in Hydra vulgaris, a member of one of the oldest metazoan phyla. We show that oocyte determination involves a mechanism that establishes a subset of precursor interstitial cells competent to differentiate into oocytes. The oocyte is singled out from this subset and the competenc...

journal_title：Developmental biology

authors： Miller MA,Technau U,Smith KM,Steele RE

更新日期：2000-08-15 00:00:00

abstract：:In neural plate stage Xenopus embryos, XlHbox 8 expression marks anterior endodermal cells fated to develop into pancreas/duodenum, and expression continues in adult pancreas in exocrine duct, acinar, and islet cells. Here, XlHbox 8 is used as a marker in experiments addressing the mechanisms of early endodermal patte...

journal_title：Developmental biology

authors： Gamer LW,Wright CV

更新日期：1995-09-01 00:00:00

abstract：:Mechanisms coupling growth and metabolism are conserved in Drosophila and mammals. In metazoans, such coupling is achieved across tissue scales through the regulated secretion of chemical messengers such as insulin that control the metabolism and growth of cells. Although the regulated secretion of Insulin like peptid...

journal_title：Developmental biology

authors： Ashe S,Malhotra V,Raghu P

更新日期：2018-02-01 00:00:00

abstract：:Despite 30 years of Hox gene study, we have a remarkably limited knowledge of the downstream target genes that Hox transcription factors regulate to confer regional identity. Here, we have used a microarray approach to identify genes that function downstream of a single vertebrate Hox gene, zebrafish hoxb1a. This gene...

journal_title：Developmental biology

authors： Rohrschneider MR,Elsen GE,Prince VE

更新日期：2007-09-15 00:00:00