Evolution of defective-interfering double-stranded RNAs of the yeast killer virus.

abstract：:Cell-free translation of separated Sendai virus mRNA species identified the message for polypeptide M and suggested the identity of the message for polypeptide NP. ...

journal_title：Journal of virology

authors： Jones K,Pridgen C,Kingsbury DW

更新日期：1978-10-01 00:00:00

abstract：:The adenovirus major late transcription unit (MLTU) encodes five families of mRNAs, L1 to L5, each distinguished by a unique poly(A) site. Use of the promoter-proximal L1 poly(A) site predominates during early infection, whereas poly(A) site choice shifts to the promoter-distal sites during late infection. A mini-MLTU...

journal_title：Journal of virology

authors： Gilmartin GM,Hung SL,DeZazzo JD,Fleming ES,Imperiale MJ

更新日期：1996-03-01 00:00:00

abstract：:Relatively little is known at the functional genomic level about the global host response to human immunodeficiency virus type 1 (HIV-1) infection. Microarray analyses by several laboratories, including our own, have revealed that HIV-1 infection causes significant changes in host mRNA abundance and regulation of seve...

journal_title：Journal of virology

authors： Chan EY,Qian WJ,Diamond DL,Liu T,Gritsenko MA,Monroe ME,Camp DG 2nd,Smith RD,Katze MG

更新日期：2007-07-01 00:00:00

abstract：:We have selected an HXB2 variant which can replicate in the presence of a neutralizing human serum. Sequencing of the gp120 region of the env gene from the variant and parental viruses identified a single amino acid substitution in the third conserved region of gp120 at residue 375 (AGT-->AAT, Ser-->Asn; designated 37...

journal_title：Journal of virology

authors： McKeating JA,Bennett J,Zolla-Pazner S,Schutten M,Ashelford S,Brown AL,Balfe P

更新日期：1993-09-01 00:00:00

abstract：:This report describes the results of experiments to determine whether chimeras between a retrovirus and portions of Ty3 are active in vivo. A chimera between Ty3 and a Neo(r)-marked Moloney murine leukemia virus (M-MuLV) was constructed. The C-terminal domain of M-MuLV integrase (IN) was replaced with the C-terminal d...

journal_title：Journal of virology

authors： Dildine SL,Respess J,Jolly D,Sandmeyer SB

更新日期：1998-05-01 00:00:00

abstract：:Plus-strand RNA viruses characteristically replicate their genome in association with altered cellular membranes. In the present study, the capacity of hepatitis C virus (HCV) proteins to elicit intracellular membrane alterations was investigated by expressing, in tetracycline-regulated cell lines, a comprehensive pan...

journal_title：Journal of virology

authors： Egger D,Wölk B,Gosert R,Bianchi L,Blum HE,Moradpour D,Bienz K

更新日期：2002-06-01 00:00:00

abstract：:We generated a recombinant influenza A virus (Mmut) that produced low levels of matrix (M1) and M2 proteins in infected cells. Mmut virus propagated to significantly lower titers than did wild-type virus in cells infected at low multiplicity. By contrast, virion morphology and incorporation of viral proteins and vRNAs...

journal_title：Journal of virology

authors： Bourmakina SV,García-Sastre A

更新日期：2005-06-01 00:00:00

abstract：:Homozygous human immunodeficiency virus type 1 (HIV-1)-transgenic mice (Tg26) appear normal at birth but die within 3 to 4 weeks. The skin of these animals shows diffuse scaling and high-level expression of both HIV-1 mRNA and gp120. Previous experiments showed that treatment with human chorionic gonadatropin (hCG) pr...

journal_title：Journal of virology

authors： De SK,Devadas K,Notkins AL

更新日期：2002-11-01 00:00:00

abstract：:The vast majority of recombinant polytropic murine leukemia viruses (MuLVs) generated in mice after infection by ecotropic MuLVs can be classified into two major antigenic groups based on their reactivities to two monoclonal antibodies (MAbs) termed Hy 7 and 516. These groups very likely correspond to viruses formed b...

journal_title：Journal of virology

authors： Lavignon M,Richardson J,Evans LH

更新日期：1997-11-01 00:00:00

abstract：:The B19 parvovirus, a small single-stranded DNA virus of 5.4 kilobases, is pathogenic in humans. B19 has remarkable specificity for erythroid progenitor cells and has been propagated in vitro only with human erythroid bone marrow. Replication of viral DNA and the viral protein products of B19 appear similar to those o...

journal_title：Journal of virology

authors： Ozawa K,Ayub J,Hao YS,Kurtzman G,Shimada T,Young N

更新日期：1987-08-01 00:00:00

abstract：:Cyclooxygenase-2 (COX-2) is a cellular enzyme in the eicosanoid synthetic pathway that mediates the synthesis of prostaglandins from arachidonic acid. The eicosanoids function as critical regulators of a number of cellular processes, including the acute and chronic inflammatory response, hemostasis, and the innate imm...

journal_title：Journal of virology

authors： Rue CA,Jarvis MA,Knoche AJ,Meyers HL,DeFilippis VR,Hansen SG,Wagner M,Früh K,Anders DG,Wong SW,Barry PA,Nelson JA

更新日期：2004-11-01 00:00:00

abstract：:Severe acute respiratory syndrome (SARS) is caused by a novel coronavirus termed SARS-CoV. We and others have previously shown that the replication of SARS-CoV can be suppressed by exogenously added interferon (IFN), a cytokine which is normally synthesized by cells as a reaction to virus infection. Here, we demonstra...

journal_title：Journal of virology

authors： Spiegel M,Pichlmair A,Martínez-Sobrido L,Cros J,García-Sastre A,Haller O,Weber F

更新日期：2005-02-01 00:00:00

abstract：:Our study was designed to investigate the nature of an antigen-specific suppressor factor generated by antigen-stimulated herpes simplex virus (HSV)-immune splenocytes. Factor SF-200, a 90,000- to 100,000-dalton fraction obtained after Sephacryl gel filtration, suppressed the generation of HSV-specific cytotoxic T-lym...

journal_title：Journal of virology

authors： Horohov DW,Wyckoff JH 3rd,Moore RN,Rouse BT

更新日期：1986-05-01 00:00:00

abstract：:Adeno-associated virus serotype 9 (AAV9) vectors show promise for gene therapy of a variety of diseases due to their ability to transduce multiple tissues, including heart, skeletal muscle, and the alveolar epithelium of the lung. In addition, AAV9 is unique compared to other AAV serotypes in that it is capable of sur...

journal_title：Journal of virology

authors： Bell CL,Gurda BL,Van Vliet K,Agbandje-McKenna M,Wilson JM

更新日期：2012-07-01 00:00:00

abstract：:Studies of rotavirus morphogenesis, transport, and release have shown that although these viruses are released from the apical surface of polarized intestinal cells before cellular lysis, they do not follow the classic exocytic pathway. Furthermore, increasing evidence suggests that lipid rafts actively participate in...

journal_title：Journal of virology

authors： Cuadras MA,Bordier BB,Zambrano JL,Ludert JE,Greenberg HB

更新日期：2006-04-01 00:00:00

abstract：:Different tombusviruses were able to support the replication of either homologous or heterologous defective interfering (DI) RNAs, and those infected plants usually developed typical attenuated symptoms. However, in some helper virus-DI RNA combinations the inoculated plants were necrotized, although they contained a ...

journal_title：Journal of virology

authors： Havelda Z,Szittya G,Burgyán J

更新日期：1998-07-01 00:00:00

abstract：:Corynebacteriophages beta and gamma are closely related but heteroimmune; hence, gamma reproduces in C7(beta). A series of gamma mutants, designated gamma-bin (beta-inhibited), has been isolated. They reproduce in only 2 to 14% of infected C7(beta) cells, and, as a result, plaque with an efficiency of 10(-4) to 10(-5)...

journal_title：Journal of virology

authors： Groman N,Rabin M

更新日期：1978-10-01 00:00:00

abstract：:ABT-378, a new human immunodeficiency virus type 1 (HIV-1) protease inhibitor which is significantly more active than ritonavir in cell culture, is currently under investigation for the treatment of AIDS. Development of viral resistance to ABT-378 in vitro was studied by serial passage of HIV-1 (pNL4-3) in MT-4 cells....

journal_title：Journal of virology

authors： Carrillo A,Stewart KD,Sham HL,Norbeck DW,Kohlbrenner WE,Leonard JM,Kempf DJ,Molla A

更新日期：1998-09-01 00:00:00

abstract：:Rio Bravo virus (RBV) is a member of the family Flaviviridae, genus Flavivirus. It belongs to a group of viruses in the genus with no known vector. In this report, we analyze the complete genome of the prototype RBV, strain M64. ...

journal_title：Journal of virology

authors： Volkova E,Tesh RB,Monath TP,Vasilakis N

更新日期：2012-04-01 00:00:00

abstract：:A ribonucleic acid (RNA)-dependent RNA polymerase was induced in chick embryo fibroblast cells after infection with Sendai virus (parainfluenza 1 virus). The enzyme was associated with the microsomal fraction of infected cells and reached maximum detectable activity at 18 hr after virus infection. The activity of the ...

journal_title：Journal of virology

authors： Mahy BW,Hutchinson JE,Barry RD

更新日期：1970-06-01 00:00:00

abstract：:The coding properties of RNA transcribed in vitro by purified vaccinia cores have been investigated using Krebs ascites tumor cells, L cells, and reticulocyte lysates. Six to 10 proteins synthesized in vitro are separated on polyacrylamide gels by electrophoresis in the presence of sodium dodecyl sulfate. Their molecu...

journal_title：Journal of virology

authors： Jaureguiberry G,Ben-Hamida F,Chapeville F,Beaud G

更新日期：1975-06-01 00:00:00

abstract：:Inhibition of RNA synthesis of the LH strain of type 3 poliovirus at the restrictive temperature occurs concurrently with the breakdown of noncapsid virus-specific peptide 2. This finding, along with other reported data (B.D. Korant, In Proteases and Biological Control, p. 621-644, 1975), suggests that noncapsid virus...

journal_title：Journal of virology

authors： Bowles SA,Tershak DR

更新日期：1978-08-01 00:00:00

abstract：:It has previously been shown that an electrophoretic variant form of the Rous sarcoma virus transforming protein, pp60v-src, exists in src-transformed cells. This variant, which was readily observed in vanadate-treated cells, was characterized as possessing extensive amino-terminal domain phosphotyrosine modification....

journal_title：Journal of virology

authors： Collett MS,Belzer SK

更新日期：1987-05-01 00:00:00

abstract：:Superinfection exclusion is the ability of an established viral infection to interfere with a second viral infection. Using West Nile virus (WNV) as a model, we show that replicating replicons in BHK-21 cells suppress subsequent WNV infection. The WNV replicon also suppresses superinfections of other flaviviruses but ...

journal_title：Journal of virology

authors： Zou G,Zhang B,Lim PY,Yuan Z,Bernard KA,Shi PY

更新日期：2009-11-01 00:00:00

abstract：:HIV circumvents HLA class I-restricted CD8+ T-cell responses through selection of escape mutations that leave characteristic mutational "footprints," also known as HLA-associated polymorphisms (HAPs), on HIV sequences at the population level. While many HLA footprints are universal across HIV subtypes and human popula...

journal_title：Journal of virology

authors： Soto-Nava M,Avila-Ríos S,Valenzuela-Ponce H,García-Morales C,Carlson JM,Tapia-Trejo D,Garrido-Rodriguez D,Alva-Hernández SN,García-Tellez TA,Murakami-Ogasawara A,International HIV Adaptation Collaborative.,Mallal SA,John M,Broc

更新日期：2018-01-02 00:00:00

abstract：:The herpes simplex virus type 1 latency-associated transcript (LAT) inhibits apoptosis. We demonstrate here that LAT influences the accumulation of the Bcl-x(L) transcript versus the Bcl-x(S) transcript in Neuro-2A cells. Bcl-x(L) encodes an antiapoptotic protein, whereas Bcl-x(S) encodes a proapoptotic protein. Promo...

journal_title：Journal of virology

authors： Peng W,Henderson G,Perng GC,Nesburn AB,Wechsler SL,Jones C

更新日期：2003-10-01 00:00:00

abstract：:Apoptosis of infected cells is critically involved in antiviral defense. Apoptosis, however, may also support the release and spread of viruses. Although the elimination of infected hepatocytes is required to combat hepatitis B virus (HBV) infection, it is still unknown which consequences hepatocyte apoptosis has for ...

journal_title：Journal of virology

authors： Arzberger S,Hösel M,Protzer U

更新日期：2010-11-01 00:00:00

abstract：:Several arenaviruses, chiefly Lassa virus (LASV) and Junin virus in West Africa and Argentina, respectively, cause hemorrhagic fever (HF) disease in humans that is associated with high morbidity and significant mortality. The investigation of antiviral strategies to combat HF arenaviruses is hampered by the requiremen...

journal_title：Journal of virology

authors： Rodrigo WW,de la Torre JC,Martínez-Sobrido L

更新日期：2011-02-01 00:00:00

abstract：:Borna disease virus (BDV) is a neurotropic virus with a broad host and geographic range. Lewis rats were immunized against BDV with a recombinant vaccinia virus expressing the BDV nucleoprotein and were later infected with BDV to evaluate protection against Borna disease (BD). Relative to animals that were not immuniz...

journal_title：Journal of virology

authors： Lewis AJ,Whitton JL,Hatalski CG,Weissenböck H,Lipkin WI

更新日期：1999-03-01 00:00:00

abstract：:Some paramyxovirus V proteins induce STAT protein degradation, and the amino acids essential for this process in the human parainfluenza virus type 2 (hPIV2) V protein have been studied. Various recombinant hPIV2s and cell lines constitutively expressing various mutant V proteins were generated. We found that V protei...

journal_title：Journal of virology

authors： Nishio M,Tsurudome M,Ito M,Garcin D,Kolakofsky D,Ito Y

更新日期：2005-07-01 00:00:00