Response of mononuclear leukocyte cyclic adenosine monophosphate-phosphodiesterase activity to treatment with topical fluorinated steroid ointment in atopic dermatitis.

abstract：:Photodynamic therapy (PDT) is a treatment based on the accumulation of a photosensitizer in the target cells and their selective destruction by irradiation with visible light. In the past 10 years, several patients with cutaneous T cell lymphoma have been successfully treated. The use of PDT in cutaneous B cell lympho...

journal_title：Journal of the American Academy of Dermatology

authors： Mori M,Campolmi P,Mavilia L,Rossi R,Cappugi P,Pimpinelli N

更新日期：2006-03-01 00:00:00

abstract：:Collodion baby is an uncommon clinical presentation of several genetic conditions, primarily disorders of cornification. The severely compromised epidermal barrier presents the greatest challenge during the newborn period and advances in neonatal care have significantly improved the prognosis. This review summarizes t...

journal_title：Journal of the American Academy of Dermatology

authors： Prado R,Ellis LZ,Gamble R,Funk T,Arbuckle HA,Bruckner AL

更新日期：2012-12-01 00:00:00

abstract：:Erythematous papulonodules that resembled a malignant lymphoma developed in a 62-year-old man. Further examination revealed that he had primary myelofibrosis with cutaneous extramedullary hematopoiesis. All three marrow elements (myeloid, erythroid, and megakaryocytic series) were present in the skin lesions. Although...

journal_title：Journal of the American Academy of Dermatology

authors： Mizoguchi M,Kawa Y,Minami T,Nakayama H,Mizoguchi H

更新日期：1990-02-01 00:00:00

abstract：:UVB irradiation is known to produce DNA damage at mutation hotspots in the p53 tumor suppressor gene, leading to the development of skin cancers. Mutations in the PTCH tumor suppressor gene, which is known to be responsible for the development of nevoid basal cell carcinoma syndrome, have also been identified in spora...

journal_title：Journal of the American Academy of Dermatology

authors： Ratner D,Peacocke M,Zhang H,Ping XL,Tsou HC

更新日期：2001-02-01 00:00:00

abstract：:Cutaneous fungal infections are a major source of morbidity in HIV-infected patients, and their management poses special challenges. Superficial mycoses, such as tinea pedis, tinea cruris, tinea corporis, and onychomycosis, are no more common in HIV-infected patients than in the HIV-negative population but are of grea...

journal_title：Journal of the American Academy of Dermatology

authors： Elmets CA

更新日期：1994-09-01 00:00:00

abstract：:A 45-year-old woman developed chronic urticaria clinically and cutaneous necrotizing vasculitis histologically, with arthralgias, abdominal pain, angioedema, hemoptysis, and pleuritic chest pain. An open lung biopsy revealed a leukocytoclastic vasculitis of the pulmonary venules, which may be etiologically associated ...

journal_title：Journal of the American Academy of Dermatology

authors： Falk DK

更新日期：1984-08-01 00:00:00

abstract：BACKGROUND:The co-existence of hidradenitis suppurativa (HS) and atopic dermatitis (AD) had been reported but was not investigated in controlled studies. OBJECTIVE:To evaluate the bidirectional association between HS and AD. METHODS:A population-based retrospective cohort study was conducted to compare incidence rate...

journal_title：Journal of the American Academy of Dermatology

authors： Sherman S,Kridin K,Bitan DT,Leshem YA,Hodak E,Cohen AD

更新日期：2020-12-27 00:00:00

abstract：:Nasal and perinasal defects provide the dermatologic surgeon a challenge. It is necessary that the dermatologic surgeon assess each defect and patient individually for optimal repair. Many reconstructive options exist. This report demonstrates the technique of the transposition island pedicle flap which may be useful ...

journal_title：Journal of the American Academy of Dermatology

authors： Campbell LB,Ramsey ML

更新日期：2008-03-01 00:00:00

abstract：:There is significant confusion in the literature when describing vascular anomalies, and vascular malformations are often misnamed or incorrectly classified. Part I of this two-part series on the diagnosis and management of extensive vascular malformations of the lower limbs will discuss the dermatologist's role in th...

journal_title：Journal of the American Academy of Dermatology

authors： Redondo P,Aguado L,Martínez-Cuesta A

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Australia's first dedicated photodermatology clinic was established at St Vincent's Hospital Melbourne in 1993. OBJECTIVE:We sought to review clinical diagnoses and results of investigations performed on patients seen at this institution. METHODS:A database was created to enable a retrospective and prospec...

journal_title：Journal of the American Academy of Dermatology

authors： Crouch RB,Foley PA,Baker CS

更新日期：2003-05-01 00:00:00

abstract：:A panel of antibodies reactive in routinely fixed, paraffin-embedded tissue sections was compared with a panel of antibodies reactive in frozen sections for the immunophenotyping of cutaneous lymphoproliferative disorders. Three T cell-associated markers (UCHL1, MT-1, MT-2, six B cell-associated markers (MB-1, MB-2, L...

journal_title：Journal of the American Academy of Dermatology

authors： Cerroni L,Smolle J,Soyer HP,Martinez Aparicio A,Kerl H

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:Whole-body imaging is the current standard of care for staging all patients presenting with skin lesions of B-cell lymphomas (BCLs), regardless of skin disease extent; however, supporting data are lacking. OBJECTIVE:To determine the clinical utility of imaging in the detection of systemic involvement in low...

journal_title：Journal of the American Academy of Dermatology

authors： Kheterpal MK,Dai J,Geller S,Pulitzer M,Ni A,Myskowski PL,Moskowitz A,Kim J,Hong EK,Fong S,Hoppe RT,Kim YH,Horwitz SM

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:The concept of contact allergy aggravating or inducing oral lichenoid mucositis diagnosed as oral lichen planus (OLP) is well recognized but somewhat controversial. OBJECTIVE:We sought to identify clinically relevant contact allergens that may be important in the management of patients with OLP. METHODS:We...

journal_title：Journal of the American Academy of Dermatology

authors： Yiannias JA,el-Azhary RA,Hand JH,Pakzad SY,Rogers RS 3rd

更新日期：2000-02-01 00:00:00

abstract：:We report the first case of acral localized acquired cutis laxa. The skin laxity was preceded by swelling of the fingers and toes and by the appearance of papular urticaria. Dapsone therapy was effective in controlling the swelling. Examination of skin biopsy specimens showed fragmentation and almost total loss of ela...

journal_title：Journal of the American Academy of Dermatology

authors： Fisher BK,Page E,Hanna W

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:Lipodermatosclerosis is a sequela of deep venous insufficiency and a risk factor for the occurrence of venous leg ulceration. Medical compression stockings facilitate leg ulcer healing and prevent occurrence of ulcers resulting from removal of edema. Although the exact level of compression necessary for remo...

journal_title：Journal of the American Academy of Dermatology

authors： Gniadecka M,Karlsmark T,Bertram A

更新日期：1998-12-01 00:00:00

abstract：:Pathologic T-cell activation is implicated in psoriasis progression. CD80, a costimulatory molecule involved in T-cell activation, likely plays a key role. IDEC-114, an IgG(1) anti-CD80 antibody, was evaluated for safety, pharmacokinetics, and preliminary clinical activity in this open-label, single-dose, dose-escalat...

journal_title：Journal of the American Academy of Dermatology

authors： Gottlieb AB,Lebwohl M,Totoritis MC,Abdulghani AA,Shuey SR,Romano P,Chaudhari U,Allen RS,Lizambri RG

更新日期：2002-11-01 00:00:00

abstract：:Pyoderma gangrenosum is a rare and often painful skin disease that can be unpredictable in its response to treatment. There is currently no gold standard of treatment or published algorithm for choice of therapy. The majority of data comes from case studies that lack a standard protocol not only for treatment administ...

journal_title：Journal of the American Academy of Dermatology

authors： Miller J,Yentzer BA,Clark A,Jorizzo JL,Feldman SR

更新日期：2010-04-01 00:00:00

abstract：:Lobular capillary hemangioma and bacillary angiomatosis due to Bartonella infection share several clinical and histopathologic characteristics. We sought to determine whether lobular capillary hemangioma is caused by the same agent as bacillary angiomatosis. Forty-five pathology specimens with a histologic diagnosis o...

journal_title：Journal of the American Academy of Dermatology

authors： Levy I,Rolain JM,Lepidi H,Raoult D,Feinmesser M,Lapidoth M,Ben-Amitai D

更新日期：2005-12-01 00:00:00

abstract：:We report the coexistence of pemphigus vulgaris and Paget's disease of the nipple in a patient with a documented history of pemphigus and a 2-year complaint of an eczematous breast lesion. A biopsy taken from the lesion showed the characteristic histologic features of both pemphigus and Paget's disease of the nipple. ...

journal_title：Journal of the American Academy of Dermatology

authors： Rae V,Gould E,Ibe MJ,Penneys NS

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Interleukin 4 is one of many cytokines under investigation about its possible role in the pathogenesis and treatment of disease. Transient acantholytic dermatosis is of uncertain origin. It has not previously been linked to drug ingestion and is generally not believed to have an immunologic basis. OBJECTIVE...

journal_title：Journal of the American Academy of Dermatology

authors： Mahler SJ,De Villez RL,Pulitzer DR

更新日期：1993-08-01 00:00:00

abstract：:Since proteolytic processes are prominent in psoriasis, sera of forty-five psoriatics were examined for alpha 1-antitrypsin (alpha 1-AT) phenotype and eighteen sera, for alpha 1-AT content and function. Five sera (11.1%) had heterozygous phenotypes (2 MZ and 3 MS), a prevalence of Z and S variants similar to that repo...

journal_title：Journal of the American Academy of Dermatology

authors： Lipkin G,Galdston M,Kueppers F

更新日期：1984-10-01 00:00:00

abstract：BACKGROUND:In animal models, extracts from green tea have been shown to be remarkably effective at reducing the severity of adverse human health effects of overexposure to ultraviolet (UV) radiation. Although sunscreens and other photoprotective measures have traditionally been used for this purpose, there is a need fo...

journal_title：Journal of the American Academy of Dermatology

authors： Elmets CA,Singh D,Tubesing K,Matsui M,Katiyar S,Mukhtar H

更新日期：2001-03-01 00:00:00

abstract：:Four female patients with chromoblastomycosis were completely cured by prolonged topical application of tolerable heat from pocket warmers. The lesions involuted after 2, 3, and 6 months, respectively, in three patients who faithfully followed our strict treatment schedule, in contrast to the fourth patient who perfor...

journal_title：Journal of the American Academy of Dermatology

authors： Tagami H,Ginoza M,Imaizumi S,Urano-Suehisa S

更新日期：1984-04-01 00:00:00

abstract：BACKGROUND:Voriconazole, an antifungal agent, is associated with various cutaneous reactions, including phototoxicity, accelerated photoaging, and skin cancer. Incidence and risk factors for these reactions in children have not been well described. OBJECTIVE:We sought to determine the incidence of and factors associat...

journal_title：Journal of the American Academy of Dermatology

authors： Sheu J,Hawryluk EB,Guo D,London WB,Huang JT

更新日期：2015-02-01 00:00:00

abstract：:Methotrexate is a useful antimetabolite for the treatment of both benign and malignant proliferative disorders. When the pharmacokinetics and potential toxicity of this drug are understood, treatment regimens can be tailored to the underlying kinetics of the target population. With the appropriate knowledge of the imp...

journal_title：Journal of the American Academy of Dermatology

authors： Olsen EA

更新日期：1991-08-01 00:00:00

abstract：UNLABELLED:Sentinel lymph node biopsy for melanoma was introduced in the early 1990s as a minimally invasive method of identifying and pathologically staging regional lymph node basins in patients with clinical stage I/II melanoma. Numerous large trials have demonstrated that sentinel lymph node evaluation has utility ...

journal_title：Journal of the American Academy of Dermatology

authors： Stebbins WG,Garibyan L,Sober AJ

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Cutaneous calcification is an acquired disorder whereby insoluble, amorphous calcium salts deposit in the skin. Classically, cutaneous calcification is categorized as metastatic, dystrophic, idiopathic, or iatrogenic. OBJECTIVE:The purpose of this study was to further elucidate the underlying pathogenic mec...

journal_title：Journal of the American Academy of Dermatology

authors： Pugashetti R,Shinkai K,Ruben BS,Grossman ME,Maldonado J,Fox LP

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Atypical fibroxanthoma (AFX) is a fibrohistiocytic tumor with relatively high local recurrence rates but low metastatic potential. Wide local excision (WLE) and Mohs micrographic surgery (MMS) are common treatments, although no consensus exists regarding optimal therapy. OBJECTIVE:To systematically review e...

journal_title：Journal of the American Academy of Dermatology

authors： Tolkachjov SN,Kelley BF,Alahdab F,Erwin PJ,Brewer JD

更新日期：2018-11-01 00:00:00

abstract：:Three patients who had cardiac surgery developed a transient, noninflammatory subepidermal bullous eruption on the legs after epsilon-aminocaproic acid infusion. Fibrin thrombi were demonstrated in papillary dermal vessels. The use of epsilon-aminocaproic acid as an antifibrinolytic agent may predispose patients to cu...

journal_title：Journal of the American Academy of Dermatology

authors： Brooke CP,Spiers EM,Omura EF

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:The use of immunotherapies in the treatment of metastatic cancers has significantly advanced oncology. However, due to safety concerns, solid organ transplant recipients (SOTRs) are routinely excluded from immunotherapy trials; thus, there is limited data for these agents in this population. METHODS:A syste...

journal_title：Journal of the American Academy of Dermatology

authors： Fisher J,Zeitouni N,Fan W,Samie FH

更新日期：2020-06-01 00:00:00