Cutaneous extramedullary hematopoiesis in myelofibrosis.

abstract：:Dermatomyositis (DM) is an idiopathic inflammatory myopathy. The mainstay of treatment for DM is oral corticosteroids. However, the dose and length of treatment is debated. Adding to the confusion, there have been no randomized controlled studies comparing the use of various corticosteroid doses and taper rates, and n...

journal_title：Journal of the American Academy of Dermatology

authors： Iorizzo LJ 3rd,Jorizzo JL

更新日期：2008-07-01 00:00:00

abstract：:The Papillon-Lefèvre syndrome is characterized by palmoplantar hyperkeratosis and juvenile periodontitis that results in the precocious loss of both the deciduous and permanent teeth. We report a patient with Papillon-Lefèvre syndrome associated with acroosteolysis, an association that has not been previously describe...

journal_title：Journal of the American Academy of Dermatology

authors： Trattner A,David M,Sandbank M

更新日期：1991-05-01 00:00:00

abstract：:The sudden eruption of atypical and benign melanocytic nevi has been associated with a number of disease states and primary skin conditions. Most case reports and series of patients have linked eruptive nevi with blistering skin disease or immunosuppression. Subsets of patients in the immunosuppressed category have re...

journal_title：Journal of the American Academy of Dermatology

authors： Woodhouse J,Maytin EV

更新日期：2005-05-01 00:00:00

abstract：:We describe a patient with chronic actinic dermatitis whose photopatch tests revealed reactions to musk ketone and musk ambrette, both of which were found in his aftershave lotion. Minimal erythema doses of UVA and UVB were decreased. After initial unsuccessful treatment with PUVA therapy the patient was successfully ...

journal_title：Journal of the American Academy of Dermatology

authors： Gardeazábal J,Arregui MA,Gil N,Landa N,Ratón JA,Diáz-Pérez JL

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:Fibrous hamartoma (FH) of infancy is a benign mesenchymal tumor, occurring as a superficial mass. Complete excision is curative. OBJECTIVE AND METHODS:The clinical features and treatment results of 18 children with FH are described. RESULTS:Local excision was the most common procedure. Surgery was radical ...

journal_title：Journal of the American Academy of Dermatology

authors： Carretto E,Dall'Igna P,Alaggio R,Siracusa F,Granata C,Ferrari A,Cecchetto G

更新日期：2006-05-01 00:00:00

abstract：:Forty-two adults with psoriasis vulgaris were treated total body thrice weekly with both ultraviolet B (UVB) and psoralens and ultraviolet A (PUVA) with the use of protocols shown to be effective with either treatment alone. Patients previously difficult to manage with either UVB or PUVA and at least 25% psoriasis wer...

journal_title：Journal of the American Academy of Dermatology

authors： Momtaz-T K,Parrish JA

更新日期：1984-03-01 00:00:00

abstract：:From the origin of civilization the pursuit of beauty has exemplified the highest order of the human being's quest for achievement, and from the beginning, this pursuit has focused, in part, on perfecting the human form. Freed from much of the time-consuming burden of attending to elemental needs, the present generati...

journal_title：Journal of the American Academy of Dermatology

authors： Basler RS

更新日期：1989-12-01 00:00:00

abstract：BACKGROUND:The Psoriasis Area and Severity Index (PASI) is considered the gold standard assessment tool for psoriasis severity, but PASI is limited by its complexity and insensitivity in people with mild psoriasis. OBJECTIVE:We sought to evaluate the product of a Physician Global Assessment (PGA) and Body Surface Area...

journal_title：Journal of the American Academy of Dermatology

authors： Walsh JA,McFadden M,Woodcock J,Clegg DO,Helliwell P,Dommasch E,Gelfand JM,Krueger GG,Duffin KC

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Hidradenitis suppurativa (HS) is a chronic inflammatory disease involving intertriginous skin. Previous epidemiologic studies have been limited by small sample size. OBJECTIVE:We sought to describe the prevalence and comorbidities of HS in a large patient care database. METHODS:In this retrospective case-c...

journal_title：Journal of the American Academy of Dermatology

authors： Shlyankevich J,Chen AJ,Kim GE,Kimball AB

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:There are large discrepancies in reported mortality for bullous pemphigoid (BP). OBJECTIVE:We sought to determine the mortality of a large cohort of patients with BP and compare this with age-matched control subjects. METHODS:Data were collected on 223 patients with a new diagnosis of BP between 1998 and 2...

journal_title：Journal of the American Academy of Dermatology

authors： Parker SR,Dyson S,Brisman S,Pennie M,Swerlick RA,Khan R,Manos S,Korman BD,Xia Z,Korman NJ

更新日期：2008-10-01 00:00:00

abstract：:Psoriasis is a common, chronic, inflammatory, multisystem disease with predominantly skin and joint manifestations affecting approximately 2% of the population. In this fifth of 6 sections of the guidelines of care for psoriasis, we discuss the use of ultraviolet (UV) light therapy for the treatment of patients with p...

journal_title：Journal of the American Academy of Dermatology

authors： Menter A,Korman NJ,Elmets CA,Feldman SR,Gelfand JM,Gordon KB,Gottlieb A,Koo JYM,Lebwohl M,Lim HW,Van Voorhees AS,Beutner KR,Bhushan R

更新日期：2010-01-01 00:00:00

abstract：:Blistering of light-exposed skin, pink-stained fluorescing diapers, and fluorescing peripheral erythrocytes led to diagnosis of congenital porphyria in an infant born to consanguineous parents. Although massive coproporphyrinuria and coproporphyrinemia initially suggested a coproporphyrinogen oxidase deficiency disord...

journal_title：Journal of the American Academy of Dermatology

authors： Huang JL,Zaider E,Roth P,Garcia O,Pollack S,Poh-Fitzpatrick MB

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:Onychomycosis (OM) affects up to 10% of the general population and is associated with functional impairment. Clinically, OM can mimic nail psoriasis, trauma, lichen planus, oncyhogryphosis, and other disorders. Laboratory methods for diagnosing OM vary in accuracy and predictive value. Clinical clues to OM w...

journal_title：Journal of the American Academy of Dermatology

authors： Walling HW,Sniezek PJ

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:Cutaneous disease is common in patients infected with HIV-1. OBJECTIVE:The aim of our study was to identify cutaneous markers associated with HIV-1 infection and disease progression as measured by Walter Reed (WR) stage. METHODS:For 42 months we have observed 912 HIV-1-positive patients in all WR stages. A...

journal_title：Journal of the American Academy of Dermatology

authors： Smith KJ,Skelton HG,Yeager J,Ledsky R,McCarthy W,Baxter D,Turiansky GW,Wagner KF,Turianski G

更新日期：1994-11-01 00:00:00

abstract：:Vulvar melanosis is a condition in which intensely pigmented irregular macules, clinically mimicking malignant melanoma, appear on the vulva. A biopsy specimen shows only marked lower epidermal pigmentation without any melanocytic atypia or nesting. The process is benign, and reassurance is the only treatment. ...

journal_title：Journal of the American Academy of Dermatology

authors： Rudolph RI

更新日期：1990-11-01 00:00:00

abstract：:Primary cutaneous CD30 (Ki-1)-positive, large cell lymphomas (LCLs) represent a recently recognized group of cutaneous T-cell lymphomas with a favorable prognosis. The characteristic features of this cutaneous lymphoma are reviewed, differences with primary noncutaneous CD30+ LCLs emphasized, and its relation with oth...

journal_title：Journal of the American Academy of Dermatology

authors： Willemze R,Beljaards RC

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:Vitiligo is an autoimmune disease of the skin with limited treatment options; there is an urgent need to identify and validate biomarkers of disease activity to support vitiligo clinical studies. OBJECTIVE:To investigate potential biomarkers of disease activity directly in the skin of vitiligo subjects and ...

journal_title：Journal of the American Academy of Dermatology

authors： Strassner JP,Rashighi M,Ahmed Refat M,Richmond JM,Harris JE

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Intertriginous and facial involvement are manifestations of psoriasis that require a different approach than is used for typical plaque psoriasis on other skin areas. Topical corticosteroids are the primary treatment for psoriasis; however, the side effects of corticosteroids are magnified on intertriginous ...

journal_title：Journal of the American Academy of Dermatology

authors： Lebwohl M,Freeman AK,Chapman MS,Feldman SR,Hartle JE,Henning A,Tacrolimus Ointment Study Group.

更新日期：2004-11-01 00:00:00

abstract：:A case of phaeohyphomycosis caused by Phialophora richardsiae is presented. The patient was a 30-year-old man with end stage malignant lymphoma. A subcutaneous abscess that developed on the dorsum of the right foot was removed surgically but immediately recurred. The causative mold was isolated from the pus in the les...

journal_title：Journal of the American Academy of Dermatology

authors： Ikai K,Tomono H,Watanabe S

更新日期：1988-09-01 00:00:00

abstract：BACKGROUND:In infantile seborrheic dermatitis (ISD) several different pathogenetic mechanisms have been proposed. OBJECTIVE:The purpose of the study was to investigate the importance of essential fatty acids (EFAs) and their metabolites in the origin of ISD. METHODS:The serum EFA patterns of 30 children with ISD, 1 t...

journal_title：Journal of the American Academy of Dermatology

authors： Tollesson A,Frithz A,Berg A,Karlman G

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:The prognosis of drug-induced hypersensitivity syndrome (DiHS)/drug reaction with eosinophilia and systemic symptoms (DRESS) is highly unpredictable. Severe complications, either related or unrelated to cytomegalovirus (CMV) reactivation, are a highly probable cause of death. OBJECTIVES:The aim was to estab...

journal_title：Journal of the American Academy of Dermatology

authors： Mizukawa Y,Hirahara K,Kano Y,Shiohara T

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:The effects of systemic therapy on mortality risk among patients with psoriasis are not fully understood. OBJECTIVE:To evaluate the impact of systemic treatment on mortality risk in patients enrolled in the Psoriasis Longitudinal Assessment and Registry. METHODS:Nested case-control analyses were performed ...

journal_title：Journal of the American Academy of Dermatology

authors： Langley RG,Poulin Y,Srivastava B,Lafferty KP,Fakharzadeh S,Langholff W,Augustin M

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Lack of agreement on how to accurately capture disease outcomes in localized scleroderma (LS) has hindered the development of efficacious treatment protocols. The LS Cutaneous Assessment Tool (LoSCAT), consisting of the modified LS Skin Severity Index (mLoSSI) and the LS Damage Index, has potential for use i...

journal_title：Journal of the American Academy of Dermatology

authors： Kelsey CE,Torok KS

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Dermatophytic infections of the fingernail can be effectively treated with oral antifungal agents; however, a long duration of treatment, generally several months, is required for cure. OBJECTIVE:Our purpose was to compare the efficacies of short-duration treatment with terbinafine and griseofulvin in the m...

journal_title：Journal of the American Academy of Dermatology

authors： Haneke E,Tausch I,Bräutigam M,Weidinger G,Welzel D

更新日期：1995-01-01 00:00:00

abstract：:We report a 38-year-old woman with lymphomatoid papulosis (LyP) who had nodular and papulovesicular lesions develop on the genital area and oral commissure. Mucosal involvement in LyP is a rare event, and its clinical relevance is still unknown. Aggressive therapies are not recommended in patients with LyP with either...

journal_title：Journal of the American Academy of Dermatology

authors： Chimenti S,Fargnoli MC,Pacifico A,Peris K

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:BRAF mutations occur in some melanomas. We hypothesized that BRAF mutation rates may differ in melanomas found in Asian compared to white populations. OBJECTIVE:We performed a metaanalysis of BRAF mutations and their associations with the clinicopathologic characteristics of primary melanoma (PM), with a su...

journal_title：Journal of the American Academy of Dermatology

authors： Kim SY,Kim SN,Hahn HJ,Lee YW,Choe YB,Ahn KJ

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Significant unmet need exists for long-term treatment of moderate to severe atopic dermatitis (AD). OBJECTIVE:To assess the long-term safety and efficacy of dupilumab in patients with AD. METHODS:This ongoing, multicenter, open-label extension study (NCT01949311) evaluated long-term dupilumab treatment in ...

journal_title：Journal of the American Academy of Dermatology

authors： Deleuran M,Thaçi D,Beck LA,de Bruin-Weller M,Blauvelt A,Forman S,Bissonnette R,Reich K,Soong W,Hussain I,Foley P,Hide M,Bouaziz JD,Gelfand JM,Sher L,Schuttelaar MLA,Wang C,Chen Z,Akinlade B,Gadkari A,Eckert L,Da

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Olumacostat glasaretil (OG) inhibits acetyl-coenzyme A carboxylase, the enzyme responsible for the first, rate-limiting step in de novo fatty acid synthesis. OG inhibited in vitro human sebocyte lipid production and reduced in vivo sebaceous gland size in hamster ears. OBJECTIVES:Safety and efficacy of OG 7...

journal_title：Journal of the American Academy of Dermatology

authors： Bissonnette R,Poulin Y,Drew J,Hofland H,Tan J

更新日期：2017-01-01 00:00:00

abstract：:We describe a 4-year-old, otherwise healthy boy with a congenital history of a perioral and labial segmental café-au-lait macule, who was noted to have unilateral localized gingival hyperpigmentation that aligned with the café-au-lait macule. This case is highly illustrative of the embryologic timing of the genetic ev...

journal_title：Journal of the American Academy of Dermatology

authors： Sergay A,Silverberg NB

更新日期：2007-05-01 00:00:00

abstract：:Forty-seven patients with chronic venous leg ulcers were included in a randomized clinical trial to evaluate the efficacy of systemically administered antibiotics in healing with condition. One group was treated by means of elastic support bandages only, whereas the other one received the same local treatment plus sys...

journal_title：Journal of the American Academy of Dermatology

authors： Alinovi A,Bassissi P,Pini M

更新日期：1986-08-01 00:00:00