Abstract：
:Glucose and insulin levels of the cerebrospinal fluid (CSF) were changed by an infusion of either glucose, insulin or a mixture of glucose and insulin in the third ventricle of freely moving undisturbed rats. Before, during and after infusions venous blood samples were withdrawn to determine insulin- and glucose concentrations. In rats on carbohydrate rich food neither plasma insulin nor blood glucose changed during infusion of either glucose, insulin or a mixture of both. However, in rats on carbohydrate free food an immediate decline in blood glucose of about 7 mg/dl occurred 15 min after the start of the infusion. During infusion of a mixture of glucose and insulin, blood glucose rose slightly and reached a value which was in between those attained when glucose and insulin were infused separately. Plasma insulin did not change following central infusions. It is argued that the central nervous system (CNS) is sensitive to changes in CSF levels of glucose and insulin and affects peripheral glucose homeostasis mainly by changing glucose output from the liver. This action of the CNS, however, is dependent on the nutritional condition of the animal.
journal_name
Physiol Behavjournal_title
Physiology & behaviorauthors
Steffens AB,Scheurink AJ,Luiten PGdoi
10.1016/0031-9384(85)90316-6subject
Has Abstractpub_date
1985-09-01 00:00:00pages
405-10issue
3eissn
0031-9384issn
1873-507Xpii
0031-9384(85)90316-6journal_volume
35pub_type
杂志文章abstract：:Due to previous work where we have demonstrated attenuated febrile responses post-lipopolysaccharide (LPS) in calorie restricted (CR) rodents we aimed to explore metabolic rate and behavioral thermoregulation in these CR animals post-LPS. Male Sprague-Dawley rats fed ad libitum (AL) or restricted to 50% (CR50%) of the...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2012.06.009
更新日期：2012-12-05 00:00:00
abstract：:The present paper describes the development and application of an enzyme-linked immunosorbent assay (ELISA) for the assessment of beta-endorphin-like immunoreactivity (beta-ELIR) level in the hypothalamus, the periaqueductal grey (PAG) and the pituitary of DBA/2 mice that were subjected to mild social stress (aggressi...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(89)90315-6
更新日期：1989-07-01 00:00:00
abstract：:High performance liquid chromatography (HPLC) with electrochemical detection proves to be a reliable method for determination of plasma catecholamines (CA) to assess the possible role of the sympathetic nervous system (SNS) in essential hypertension (EH). The present investigation in a group of 15 normotensive (N) and...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(91)90302-5
更新日期：1991-04-01 00:00:00
abstract：:The conditioned taste aversion (CTA) is routinely used to assess the aversive consequences of anorexic agents, including potential pharmacological therapies for obesity. In a typical CTA paradigm, rats briefly sampling a novel tastant (e.g., saccharin) are acutely administered with toxin (e.g., lithium chloride, LiCl)...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(03)00189-6
更新日期：2003-09-01 00:00:00
abstract：:Dysfunction in the circadian system has been linked to emotion regulation and mood disorders with genetic variation in clock genes as likely contributors. Here, we focused on endophenotypes of affective processing and investigated in two independent samples of healthy individuals (n1=99, n2=108) whether genotypes of a...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2020.112831
更新日期：2020-05-15 00:00:00
abstract：:The present study investigated the effects of ethanol on retrieval from long-term memory by using a set of cognitive decision tasks. Male and female subjects were administered either 0.0 or 1.0 milliliter of ethanol per kilogram of body weight, and then asked to make physical, lexical, and semantic decisions about pai...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(89)90103-0
更新日期：1989-06-01 00:00:00
abstract：:Crib-biting in the horse is frequently prevented in the short-term by horse-owners using physical means. Because it has been proposed that crib-biting may function to reduce stress, the effect of prevention of crib-biting and/or eating on the behaviour, heart rate, and plasma cortisol and beta-endorphin concentrations...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(98)00070-5
更新日期：1998-08-01 00:00:00
abstract：:Feather pecking in laying hens is a serious behavioral problem and is often associated with feather eating. There is some evidence that ingested feathers affect gut function. The aim of the present study was to explore whether differences in intestinal microbial metabolites in laying hens with high and low levels of r...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2012.12.017
更新日期：2013-02-17 00:00:00
abstract：:The goal of this study was to investigate possible relationships between different aspects of behavioural decline in aged (17 months) NMRI mice by a multivariate analysis. These mice presented defects in spatial processing both in place learning in a Morris-type water maze and in spontaneous alternation in a Y-maze, a...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(93)90120-5
更新日期：1993-08-01 00:00:00
abstract：BACKGROUND:There is no consensus about how resilience is related to the different types of stress such as daily or chronic stress and psychopathology. The main objective of this study is to evaluate the relationship between resilience and the different measures of stress such as perceived stress, chronic stress, life e...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2019.02.001
更新日期：2019-04-01 00:00:00
abstract：:The aim of this study was to explore interactions between coping style and diet as risk factors for developing insulin resistance in rats. We hypothesized that rats characterized by a passive coping strategy are more susceptible for developing insulin resistance and visceral obesity than proactively coping rats, parti...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2010.04.007
更新日期：2010-06-16 00:00:00
abstract：:Ethanol is a common dietary constituent, but knowledge of its chemosensory properties and their relationship to its ingestion is limited. Twenty-five male and 25 female, light-regular ethanol consumers participated in five test sessions. Sessions involved determination of taste, olfactory and nasal irritation threshol...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(00)00397-8
更新日期：2001-01-01 00:00:00
abstract：:Mast cells are a type of immune cell widely distributed in the body of vertebrates. Mast cells have many granules that contain several bioactive molecules such as histamine, and these molecules are released through degranulation when the mast cell receives certain stimuli. Because the number of mast cells increases du...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2019.112681
更新日期：2019-11-01 00:00:00
abstract：:The present study describes changes of response enhancement of hippocampal field potentials in slices of kindled rats using different methods to induce long-lasting potentiation. Eight-week-old male Wistar rats were subjected to pentylenetetrazol (PTZ) kindling induced by intraperitoneal injection of 45 mg/kg once eve...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(97)00167-4
更新日期：1997-10-01 00:00:00
abstract：:Social agonistic behaviour of intact male rats is strongly reduced by the experience of defeat by a dominant male conspecific. Small electrolytic lesions in the corticomedial amygdala strongly affected this behavioural change due to defeat. No effects of the lesions were observed before and during the defeat. Some lea...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(84)90311-1
更新日期：1984-04-01 00:00:00
abstract：:In Experiment I, neurosensory responses from three limbic areas in the cat brain were recorded when cats of differing defensive temperamental traits were exposed to species characteristic threat. The cats investigated were more or less defensive in response to rats and conspecific threat howls. The behavioral disposit...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(91)90264-o
更新日期：1991-03-01 00:00:00
abstract：:Experiments were performed to measure the influence of centrally and peripherally applied arginine vasopressin (AVP) on anxiety-related behavior as indicated by the elevated plus maze test. Central administration was performed into the septum using a microdialysis technique. In initial experiments, the microdialysis p...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(98)00119-x
更新日期：1998-06-15 00:00:00
abstract：:Mixtures of compounds can often be tasted even when all of their components are too weak to be tasted separately. Such mixtures are said to be integrative. Integration was demonstrated by mixing compounds in concentrations proportional to their separate detection thresholds and then measuring the detection threshold o...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(97)00270-9
更新日期：1997-11-01 00:00:00
abstract：:Depression is associated with significant functional disabilities. Application of new drugs which could enhance the effectiveness of antidepressants drug and reduce side effects of their long-term use seems necessary. Citicoline is used as an effective chemical agent for improving the symptoms of some neurodegenerativ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2018.08.002
更新日期：2018-10-15 00:00:00
abstract：:Highly purified insulin-like growth factors I and II and insulin (100 ng peptide/animal) were injected intracerebroventricularly in rats and the effect on 24 hour food consumption examined. IGF-II injections resulted in a 21% decrease in food intake and 4% body weight loss over the 24 hour period following peptide adm...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(87)90279-4
更新日期：1987-01-01 00:00:00
abstract：:The consumption of a large food bolus leads to stomach distension. Gastric distension potently signals the termination of a meal by stimulating gastric mechanoreceptors and activating neuroendocrine circuitry. The ability to terminate a meal is altered in disorders such as bulimia nervosa (BN), binge-eating disorder (...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2011.11.006
更新日期：2012-02-28 00:00:00
abstract：:Television viewing (TVV) has been linked with obesity, possibly through increased sedentary behavior and/or through increased ingestion during TVV. The proposition that TVV causes increased feeding, however, has not been subjected to experimental verification until recently. Our objective was to determine if the amoun...
journal_title：Physiology & behavior
pub_type： 临床试验,杂志文章
doi：10.1016/j.physbeh.2006.05.035
更新日期：2006-07-30 00:00:00
abstract：:The predatory behavior of female ferrets shows seasonal fluctuations which appear to be affected by estradiol. Under natural lighting conditions in the laboratory the annual rhythm of the behavior was observed during anestrus, estrus, pregnancy, pseudopregnancy and lactating period. Females in heat failed to show pred...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(86)90287-8
更新日期：1986-01-01 00:00:00
abstract：:Intraperitoneal injections of the opiate antagonist naloxone decreased food intake in both vagotomized and sham-vagotomized rats. Consumption of liquid and solid sucrose, which were used in order to equate baseline intake, was equally suppressed in both groups under food-deprivation and appetitively-motivated conditio...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(82)90345-6
更新日期：1982-11-01 00:00:00
abstract：:Many diets employ regular periods of fasting that extend beyond a typical overnight fast (i.e. intermittent fasting [IF]). Evaluation of acute fasting responses provides information concerning the potential theoretical rationale for IF. The purpose of the present investigation was to assess the test-retest reliability...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2018.02.017
更新日期：2018-05-01 00:00:00
abstract：:In this report the role of olfactory bulb (OB) norepinephrine (NE) in the identification and recognition of urinary chemical cues was examined. In Experiment 1, sexually naive adult male Sprague-Dawley rats were treated with either the noradrenergic neurotoxin, DSP-4, or the water vehicle, and tested for their ability...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(93)90136-4
更新日期：1993-03-01 00:00:00
abstract：:Sufficient oral microelements such as zinc and fully chewing of foods are required to maintain cognitive function despite aging. No knowledge exists about the combination of factors such as zinc deficiency and reduced mastication on learning and memory. Here we show that tooth extraction only in 8-week-old mice did no...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2015.10.005
更新日期：2015-12-01 00:00:00
abstract：:Previous studies showed that when socially isolated at 22 degrees C, postnatal day 14 rats, but not younger day 7 rats, reduce their emission of ultrasonic vocalizations when exposed to an unfamiliar adult male rat, a naturalistic threat. Because ultrasound production is associated with factors such as age and body te...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(92)90336-z
更新日期：1992-09-01 00:00:00
abstract：:Non-alcoholic fatty liver disease (NAFLD) is a disorder observed in children and adults characterized by an accumulation of liver fat (>5% wet weight) in the absence of excessive alcohol intake. NAFLD affects 10 to 30% of the American population and is the most common cause of liver disease in the United States. NAFLD...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2012.01.008
更新日期：2012-05-15 00:00:00
abstract：:Female rats have a fertile postpartum estrus, which can result in a simultaneous gestation and lactation and later in the overlapping of two different-age litters. These different physiological and contextual situations may affect the maternal behavior of lactating rats and provoke long-lasting changes in the affectiv...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2008.02.004
更新日期：2008-03-18 00:00:00
