Abstract:
:Experiments were performed to measure the influence of centrally and peripherally applied arginine vasopressin (AVP) on anxiety-related behavior as indicated by the elevated plus maze test. Central administration was performed into the septum using a microdialysis technique. In initial experiments, the microdialysis probes were characterized for substance application in vivo by means of 125I AVP, measuring the substance-specific percent passover and the spatial distribution around the microdialysis membrane within the brain. Both microdialysis administration of 200 pg of AVP into the septum and and intraperitoneal application of 500 ng of AVP induced an increase in the percentage of time spent on the open arms of the elevated plus maze. The blockade of vasopressinergic neurotransmission or neuromodulation into the septal area by 40 ng of the AVP receptor antagonist d(CH2)5Thyr(Et)VAVP failed to induce a significant effect in this respect. The observation that neither centrally nor peripherally applied AVP influenced the locomotor activity on the elevated plus maze supports the hypothesis that AVP is involved in the modulation of anxiety-related behavior in rats.
journal_name
Physiol Behavjournal_title
Physiology & behaviorauthors
Appenrodt E,Schnabel R,Schwarzberg Hdoi
10.1016/s0031-9384(98)00119-xsubject
Has Abstractpub_date
1998-06-15 00:00:00pages
543-7issue
4eissn
0031-9384issn
1873-507Xpii
S0031-9384(98)00119-Xjournal_volume
64pub_type
杂志文章abstract::Bombesin has been shown to decrease food intake and increase the duration of slow wave sleep, as well as to increase blood glucose and glucagon. A suspected mechanism of bombesin's anorexigenic and hypnogenic action could be via its possible effect on the enhancement of metabolism itself. Therefore, the effect of bomb...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(91)90262-m
更新日期:1991-03-01 00:00:00
abstract::Feeding is critical for survival. Yet, patients with chronic pain often lose their appetite and eat less. We previously showed that ad libitum fed male rats continue to feed rather than withdraw from a brief noxious stimulus. This study examined the effects of a sustained noxious stimulus on feeding by testing ad libi...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2009.03.015
更新日期:2009-06-22 00:00:00
abstract::The consumption of a large food bolus leads to stomach distension. Gastric distension potently signals the termination of a meal by stimulating gastric mechanoreceptors and activating neuroendocrine circuitry. The ability to terminate a meal is altered in disorders such as bulimia nervosa (BN), binge-eating disorder (...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2011.11.006
更新日期:2012-02-28 00:00:00
abstract::The extent to which social living arrangements influenced seasonal changes in physiology and behavior was examined in adult squirrel monkeys (Saimiri sciureus). Data were collected over 20 months (encompassing two breeding seasons) from animals that were housed in three mixed-sex social configurations that varied in t...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(96)00134-5
更新日期:1996-10-01 00:00:00
abstract::The plasma corticosterone levels of rats were examined prior to their morning meal on Days 1, 7 and 20 of a regimen of 1 hr access daily to food mash and water. The relationship between external cues and meal provision was varied by feeding some groups immediately upon room entry each morning, and others with a variab...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(84)90097-0
更新日期:1984-08-01 00:00:00
abstract::A moderate dose of amphetamine (AMPH) produces hypoactivity around 20 h post-administration. This hypoactivity may be an indicator of an acute withdrawal state. The purpose was to see how AMPH doses affected the expression of this hypoactivity and, by inference, AMPH-induced acute withdrawal. Rats were housed in indiv...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2005.10.009
更新日期:2006-02-28 00:00:00
abstract::Puberty is a critical period for neurodevelopment of schizophrenia. In the present study, we investigated the effects of peri-pubertal social isolation on psychotic behaviors in rats and its relationship to dopamine expression. Wistar male rats were randomly divided into pubertal isolation (ISO; isolate housing, 38-51...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2009.05.021
更新日期:2009-09-07 00:00:00
abstract::STOREY, M.L. The shifting beverage landscape. PHYSIOL BEHAV, 2010. - Simultaneous lifestyle changes have occurred in the last few decades, creating an imbalance in energy intake and energy expenditure that has led to overweight and obesity. Trends in the food supply show that total daily calories available per capita ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2010.02.009
更新日期:2010-04-26 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(94)90365-4
更新日期:1994-12-01 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2004.05.011
更新日期:2004-09-30 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(99)00086-4
更新日期:1999-09-01 00:00:00
abstract::Rats' voluntary ethanol intake varies with dispositional factors and energy status. The joint influences of these were of interest here. We previously reported that rats selectively bred for high voluntary saccharin intake (HiS) consume more ethanol and express more robust conditioning of preference for flavors paired...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2012.12.001
更新日期:2013-01-17 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(96)00302-2
更新日期:1996-12-01 00:00:00
abstract::The effect of amylin injected IP on food intake in rats of different age (7-9 weeks, 3 months, 15-18 months) was investigated. The possible site of amylin action was investigated using vagotomized rats. Lastly, the influence of food composition on amylin's effect was investigated. In 12-h food-deprived old rats, food ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(94)90076-0
更新日期:1994-05-01 00:00:00
abstract::The chronically elevated heat production of lactating Norway rats makes them vulnerable to acute hyperthermia during pup contact and thereby limits the duration of such interactions. High lactational levels of progesterone and corticosterone may act in concert to increase maternal heat load. Specifically, progesterone...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(86)90094-6
更新日期:1986-01-01 00:00:00
abstract::Rats were exposed to daily sessions of either restraint plus cold, forced exercise, or grid shock for one month and then subjected to the ulcerogenic effects of either supine restraint plus cold, or activity-stress. Chronic stress generally protected against stress ulcer but the protection depended on the degree of si...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(86)90493-2
更新日期:1986-01-01 00:00:00
abstract::Rats placed as intruders in a long-established colony showed significant elevations of plasma corticosterone after 10-20 minutes of intruding. This rise was prevented by 5 days pretreatment with chlordiazepoxide (5 mg/kg). The rats resident in the colony had significantly higher basal corticosterone concentrations com...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(84)90152-5
更新日期:1984-09-01 00:00:00
abstract::The present study examined responsiveness of newborn rats to a surrogate nipple providing fluids with basic tastes (sweet, sour, bitter and salty) and assessed the effects of this first gustatory experience on subsequent responding to the nipple itself (empty nipple) or the nipple providing water. Responsiveness (atta...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(01)00672-2
更新日期:2002-06-01 00:00:00
abstract::Glycemic conditioning was investigated in four experiments in which insulin was administered to animals in particular stimulus contexts. Both hyperglycemic and hypoglycemic conditioned responses were obtained, with the directionality of the CR dependent upon which environmental complex was used as the CS. These bidire...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(84)90376-7
更新日期:1984-10-01 00:00:00
abstract::Previous studies have found that adolescent social isolation of rats can lead to an increased anxiety state during adulthood, while chronic anxiety states are associated with dysregulated local GABAergic inhibition within the basolateral amygdala (BL). Therefore, we investigated the effects of post-weaning social isol...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2012.05.007
更新日期:2012-12-05 00:00:00
abstract::The aim of this study was to differentiate between maternal and offspring factors involved in the control of milk ingestion. Specifically, we investigated: (1) the temporal pattern of milk ingestion in fasted and non-fasted sucklings; (2) the amount of milk released as compared to that of milk available; and (3) the r...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(84)90052-0
更新日期:1984-11-01 00:00:00
abstract::In the following experiments, an attempt was made to determine the role of the ovary in the control of food intake and body weight regulation during lactation. In the first study, it was found that concentrations of estradiol benzoate effective in suppressing food intake and body weight in nonlactating animals were no...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(76)90016-0
更新日期:1976-12-01 00:00:00
abstract::Although elemental perception of odor mixtures allows us to perceive the component odor qualities, configural perception leads to the emergence of a new odor percept. The 6-odorant Red Cordial (RC) mixture is weak configurally perceived in newborn rabbits, meaning that pups respond to the odorants after conditioning t...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2015.02.019
更新日期:2015-04-01 00:00:00
abstract:AIMS:Ghrelin is one of the most potent orexigens known to date. Recent data suggested that ghrelin is involved in reward-mediated processes such as the rewarding value of food. Whereas the neuronal pathways by which ghrelin regulates energy balance are well described, those involved in ghrelin-induced reward are still ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2010.12.006
更新日期:2011-03-28 00:00:00
abstract::The changes in the acquisition of conditioned avoidance responses (CARs) and the performance of some spontaneous behaviors were examined across the estrous cycle of female rats. CARs were facilitated during diestrus, impaired at proestrus and practically abolished at estrus and metestrus. Motor activity and head shaki...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(89)90010-3
更新日期:1989-09-01 00:00:00
abstract::Angiotensins, especially angiotensin IV (Ang IV), have recently been found to be potent cognitive enhancers in rodents. However, the precise mechanisms of their memory improving effects remain unknown. In this study we tested the hypothesis that D2 dopamine receptors at least partially mediate cognitive effects of Ang...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2006.03.025
更新日期:2006-06-15 00:00:00
abstract::Sheep of calm or nervous temperament differ in their physiological (cortisol secretion) and behavioural (motor activity) responses to stressors, perhaps due to variation in genes that regulate glucocorticoid synthesis or brain dopamine activity. Using ewes that had been selected over 20 generations for nervous (n=58) ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2015.10.022
更新日期:2016-01-01 00:00:00
abstract::Male mice, genetically selected for aggression, characterized by short attack latency (SAL) or long attack latency (LAL), differ on several testosterone (T)-related parameters during ontogeny and adult age. The variation in aggressive behavior at adult age may be due to differences in degree of androgenization prenata...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(93)90299-u
更新日期:1993-11-01 00:00:00
abstract::The present study describes an experiment that was carried out to study the effects of mixing pigs once at 25 kg, preceded by transportation for 1.5 h, on the behavior and the circadian rhythmicity of salivary cortisol. The frequency of agonistic interactions was higher for mixed pigs. This was not only the case immed...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(97)00037-1
更新日期:1997-07-01 00:00:00
abstract::l-phenylalanine (Phe) has been shown to elicit release of the gut hormone cholecystokinin (CCK) and reduce energy intake. Furthermore, studies in some animal models demonstrate potentiation of CCK-induced satiety by estradiol (E(2)). As E(2) is elevated in the follicular phase, we expected greater satiety effects than...
journal_title:Physiology & behavior
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.physbeh.2007.11.051
更新日期:2008-03-18 00:00:00