Abstract:
:Bombesin has been shown to decrease food intake and increase the duration of slow wave sleep, as well as to increase blood glucose and glucagon. A suspected mechanism of bombesin's anorexigenic and hypnogenic action could be via its possible effect on the enhancement of metabolism itself. Therefore, the effect of bombesin on rat metabolism was investigated in an open circuit computerized respirometer. This device was specifically conceived to extract the fraction of metabolism which is not due to the energy cost of muscular effort. This fraction of metabolism was designed background metabolism. In the absence of food, peripheral administration of bombesin increased the background metabolism at all doses. The higher dose of bombesin (32 micrograms/kg IP) elicited a four-hour enhancement of background metabolism, the magnitude of which was equivalent to that induced by a meal of about 1.5 grams. Therefore, it is suggested that the effect of bombesin on feeding and sleep could be achieved, at least partly, by its effect on the background metabolism, which ultimately may modulate the behavioral responses.
journal_name
Physiol Behavjournal_title
Physiology & behaviorauthors
Even PC,de Saint Hilaire Z,Nicolaïdis Sdoi
10.1016/0031-9384(91)90262-msubject
Has Abstractpub_date
1991-03-01 00:00:00pages
439-42issue
3eissn
0031-9384issn
1873-507Xpii
0031-9384(91)90262-Mjournal_volume
49pub_type
杂志文章abstract::The beneficial effects of touch in development were already observed in different types of skin-to-skin care. In the current study, we aimed at studying potential underlying mechanisms of these effects in terms of parasympatho-inhibitory regulation. We examined the specific impact of affective maternal stroking versus...
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更新日期:2001-03-01 00:00:00
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doi:10.1016/0031-9384(89)90241-2
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(92)90121-h
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journal_title:Physiology & behavior
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doi:10.1016/j.physbeh.2004.04.029
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journal_title:Physiology & behavior
pub_type: 杂志文章,随机对照试验
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2012.05.007
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journal_title:Physiology & behavior
pub_type: 杂志文章
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journal_title:Physiology & behavior
pub_type: 杂志文章
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(96)00500-8
更新日期:1997-05-01 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2012.04.017
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(89)90346-6
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journal_title:Physiology & behavior
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doi:10.1016/j.physbeh.2012.12.010
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pub_type: 杂志文章
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更新日期:1998-12-01 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章,评审
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更新日期:2008-09-03 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(96)00214-4
更新日期:1996-10-01 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2005.12.002
更新日期:2006-03-30 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(92)90345-3
更新日期:1992-09-01 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2018.12.010
更新日期:2019-03-15 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(91)90588-f
更新日期:1991-12-01 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(83)90099-9
更新日期:1983-07-01 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(90)90322-u
更新日期:1990-08-01 00:00:00
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journal_title:Physiology & behavior
pub_type: 临床试验,杂志文章
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更新日期:2006-08-30 00:00:00