Development and introduction of inactivated poliovirus vaccines derived from Sabin strains in Japan.

abstract：BACKGROUND:Vaccination coverage is the usual metrics to evaluate the immunization programs performance. For the 10-valent pneumococcal conjugate (PCV10) vaccine, measuring the delay of vaccination is also important, particularly as younger children are at increased risk of disease. Routinely collected administrative da...

journal_title：Vaccine

authors： Sartori AL,Minamisava R,Afonso ET,Policena GM,Pessoni GC,Bierrenbach AL,Andrade AL

更新日期：2017-02-15 00:00:00

abstract：OBJECTIVES:HIV-infected children have poor responses to inactivated influenza vaccines. Live vaccines (LAIVs) are highly efficacious in children, but they are not used in HIV-infected children du e to limited information. We investigated the safety, immunogenicity and viral shedding of LAIV4 in HIV-infected compared wi...

journal_title：Vaccine

authors： Curtis D,Ning MF,Armon C,Li S,Weinberg A

更新日期：2015-09-11 00:00:00

abstract：:The immunogenicity and reactogenicity of a booster dose of enhanced potency inactivated polio vaccine (EIPV) were evaluated in 492 healthy 12 year old adolescents. The booster was administered at the same time as the HBV vaccine compulsory in Italy at this age. Blood samples and questionnaires on reactogenicity were c...

journal_title：Vaccine

authors： Pregliasco F,Grilli G,Andreassi A,D'Addezio E,Vacca F,Squarcione S,Biasio LR,Profeta M

更新日期：1996-03-01 00:00:00

abstract：:The greatest risk from live-attenuated vaccines is reversion to virulence. Particular concerns arise for RNA viruses, which exhibit high mutation frequencies. We examined the stability of 3 attenuation strategies for the alphavirus, Venezuelan equine encephalitis virus (VEEV): a traditional, point mutation-dependent a...

journal_title：Vaccine

authors： Kenney JL,Volk SM,Pandya J,Wang E,Liang X,Weaver SC

更新日期：2011-03-09 00:00:00

abstract：:We demonstrated the feasibility of collecting and disseminating mid-season estimates of influenza vaccine coverage. We surveyed a nationally representative sample of U.S. adults (n = 3972) via the Internet about use of influenza vaccination as of mid-November 2008. Findings were presented on 10 December 2008 to the me...

journal_title：Vaccine

authors： Harris KM,Maurer J,Lurie N

更新日期：2009-06-08 00:00:00

abstract：BACKGROUND:Estimation of the magnitude of the herd effect on invasive pneumococcal disease (IPD) is important when evaluating health benefits and cost-effectiveness of paediatric pneumococcal conjugate vaccine (PCV) programmes and may influence policy makers' decisions on PCV use. Several epidemiological, programmatic,...

journal_title：Vaccine

authors： Pirçon JY,Talarico CA,Bollaerts K,Hausdorff WP,Clarke CJ

更新日期：2018-11-12 00:00:00

abstract：:Monoclonal antibodies (MoAbs) reactive with the authentic Orientia tsutsugamushi 56-kDa protein were generated. MoAb FS10 and FS15 showed in vitro, as well as, in vivo neutralizing activity upon O. tsutsugamushi infection. Deletion mutants of the gene for 56-kDa protein of O. tsutsugamushi Boryong were expressed to ma...

journal_title：Vaccine

authors： Seong SY,Kim MK,Lee SM,Odgerel Z,Choi MS,Han TH,Kim IS,Kang JS,Lim BU

更新日期：2000-08-15 00:00:00

abstract：:A rapid and sensitive assay using surface plasmon resonance (SPR) immunoassay has been developed for the detection of Clostridium perfringens beta-toxin. The SPR immunoassay was conducted off-line by passing fermentation broth by a sensor chip coated with a monoclonal antibody specific for C. perfringens beta-toxin. Q...

journal_title：Vaccine

authors： Hsieh HV,Stewart B,Hauer P,Haaland P,Campbell R

更新日期：1998-05-01 00:00:00

abstract：:Vaccination is the principal means used to control and treat porcine reproductive and respiratory syndrome virus (PRRSV) infection. An array of PRRS vaccine products is available in various regions of the world. However, despite extensive efforts, little progress has been made to improve efficacy since the first intro...

journal_title：Vaccine

authors： Murtaugh MP,Genzow M

更新日期：2011-10-26 00:00:00

abstract：:We vaccinated 15 persons, age 56 to 79 years, with 14-valent pneumococcal polysaccharide vaccine and revaccinated them with 23-valent vaccine 6 years later to assess adverse reactions and booster responses of anticapsular antibodies. No systemic reactions occurred after administration of either vaccine. After booster ...

journal_title：Vaccine

authors： Mufson MA,Hughey DF,Turner CE,Schiffman G

更新日期：1991-06-01 00:00:00

abstract：:A human hookworm vaccine is under development and in clinical trials in Africa and the Americas. The vaccine contains the Na-APR-1 and Na-GST-1 antigens. It elicits neutralizing antibodies that interfere with establishment of the adult hookworm in the gut and the ability of the parasite to feed on blood. The vaccine t...

journal_title：Vaccine

authors： Hotez PJ,Beaumier CM,Gillespie PM,Strych U,Hayward T,Bottazzi ME

更新日期：2016-06-03 00:00:00

abstract：:Previously, the Fiji Pneumococcal Project (FiPP) evaluated reduced dose immunization schedules that incorporated pneumococcal protein conjugate and/or polysaccharide vaccine (PCV7 and 23vPPV, respectively). Immune hyporesponsiveness was observed in children vaccinated with 23vPPV at 12 months of age compared with chil...

journal_title：Vaccine

authors： Boelsen LK,Dunne EM,Lamb KE,Bright K,Cheung YB,Tikoduadua L,Russell FM,Mulholland EK,Licciardi PV,Satzke C

更新日期：2015-10-13 00:00:00

abstract：:The low-molecular-mass secretory proteins of Mycobacterium tuberculosis have been shown to be major T-cell antigens during infection with the pathogenic bacterium. In this study, we determined murine T-cell epitopes on three low-molecular-mass proteins, CFP11 (Rv2433c), CFP17 (Rv1827), and TB18.5 (Rv0164) using DNA im...

journal_title：Vaccine

authors： Eweda G,Suzuki D,Nagata T,Tsujimura K,Koide Y

更新日期：2010-06-23 00:00:00

abstract：:This study demonstrates that liposomes administered to the lower respiratory tract of mice have the capacity to stimulate secretory IgA (s-IgA) antibody production in the female urogenital system. Total respiratory tract immunization of mice with influenza virus subunit antigen simply mixed with negatively charged lip...

journal_title：Vaccine

authors： de Haan A,Renegar KB,Small PA Jr,Wilschut J

更新日期：1995-05-01 00:00:00

abstract：:To study the kinetics of humoral as well as cellular immunity to measles and to test for associated immunosuppression 124 12 month old children were studied twice, before routine MMR and either 14, 22, 30, or 38 days after vaccination. Plaque reduction neutralization (PRN) titres were determined at these time points a...

journal_title：Vaccine

authors： Pabst HF,Spady DW,Carson MM,Stelfox HT,Beeler JA,Krezolek MP

更新日期：1997-01-01 00:00:00

abstract：:Plasmodium falciparum Pfs25 antigen, expressed on the surface of zygotes and ookinetes, is one of the leading targets for the development of a malaria transmission-blocking vaccine (TBV). Our laboratory has been evaluating DNA plasmid based Pfs25 vaccine in mice and non-human primates. Previously, we established that ...

journal_title：Vaccine

authors： Kumar R,Nyakundi R,Kariuki T,Ozwara H,Nyamongo O,Mlambo G,Ellefsen B,Hannaman D,Kumar N

更新日期：2013-06-28 00:00:00

abstract：:This study compared the safety and immunogenicity of DTaP₅-IPV-Hib vaccine (followed by monovalent hepatitis B vaccine [HBV]) and DTaP₃-HBV-IPV/Hib vaccines, both coadministered with PCV7, as a fourth-dose booster in toddlers 11-18 months who had a hexavalent vaccine primary series. The fever rate within 4 days of DTa...

journal_title：Vaccine

authors： Berner R,Boisnard F,Thomas S,Mwawasi G,Reynolds D

更新日期：2012-07-27 00:00:00

abstract：:Gram-positive enhancer matrix (GEM) particles, produced from non-genetically modified Lactococcus lactis bacteria have an inherent immunostimulatory activity. It was investigated whether co-administration of GEM particles can reduce the amount of influenza subunit vaccine (HA) necessary to protect mice from viral infe...

journal_title：Vaccine

authors： Saluja V,Visser MR,Ter Veer W,van Roosmalen ML,Leenhouts K,Hinrichs WL,Huckriede A,Frijlink HW

更新日期：2010-11-23 00:00:00

abstract：BACKGROUND:Influenza vaccination is recommended for immunocompromised patients. METHODS:Children (6 months to 21 years) with cancer, HIV infection, or sickle cell disease (SCD) received 1 or 2 doses of pandemic 2009 H1N1 monovalent influenza vaccine (H1N1 MIV). Safety and tolerability, hemagglutination inhibition (HI)...

journal_title：Vaccine

authors： Hakim H,Allison KJ,Van De Velde LA,Li Y,Flynn PM,McCullers JA

更新日期：2012-01-20 00:00:00

abstract：:The hepatitis B virus (HBV) has infected more than 2000 million persons alive today and 350 million persons are chronically infected carriers of the virus, at high risk of death from active hepatitis, cirrhosis and primary hepatocellular cancer. Each year approximately 1 million people die from the acute and chronic s...

journal_title：Vaccine

authors： Kane M

更新日期：1995-01-01 00:00:00

abstract：:We recently reported that administration of low doses of myotoxins at vaccination sites potentiated antigen-specific T-cell immunity induced by genetic cancer vaccines in mice, an effect which was superior to TLR agonists. In the current study, we found unexpectedly that the mechanism of this potent adjuvant effect wa...

journal_title：Vaccine

authors： Qin H,Cha SC,Neelapu SS,Liu C,Wang YH,Wei J,Qin XF,Liu YJ,Kwak LW

更新日期：2010-11-23 00:00:00

abstract：:We recently reported an attenuated EIAV vaccine study that directly examined the effect of lentiviral envelope sequence variation on vaccine efficacy. The study [1] demonstrated for the first time the failure of an ancestral vaccine to protect and revealed a significant, inverse, linear relationship between envelope d...

journal_title：Vaccine

authors： Craigo JK,Barnes S,Cook SJ,Issel CJ,Montelaro RC

更新日期：2010-11-29 00:00:00

abstract：:Different subsets of dendritic cells (DC) elicit qualitatively different immune responses. In mice, two lymphoid tissue-resident subsets, CD8α(+) and CD8α(-), have been implicated in the induction of T helper 1 (Th1) or Th2 responses, respectively. Moreover, CD8α(+) DC appear to play a major role in priming CD8(+) T l...

journal_title：Vaccine

authors： Suleman M,Galea S,Gavard F,Merillon N,Klonjkowski B,Tartour E,Richardson J

更新日期：2011-08-11 00:00:00

abstract：:A newly developed human diploid cell rabies vaccine (Lyssavac-HDC), produced without added serum albumin and with an effort to remove the virus-inactivating beta-propriolactone prior to addition of the gelatin, L-cysteine and potassium phosphate stabilizer, was tested for safety immunogenicity, adverse reactions and e...

journal_title：Vaccine

authors： Wilde H,Glueck R,Khawplod P,Cryz SJ,Tantawichien T,Thipkong P,Chomchey P,Prakongsri S,Benjavongkulchai M,Sumboonanondha A

更新日期：1995-04-01 00:00:00

abstract：:Triton X-100 (TX-100) is the most common surfactant used to split viruses during the production of influenza split-virus vaccines. It is a mild surfactant not known to denature the viral proteins; this property makes TX-100 useful for maintaining antigen conformational structure, and, as an added benefit, for partiall...

journal_title：Vaccine

authors： Sahin Z,Neeleman R,Haines J,Kayser V

更新日期：2019-02-14 00:00:00

abstract：:Bovine tuberculosis (bTB) is increasing in incidence in the UK. Effective control strategies could involve vaccination; BCG, either alone or in prime-boost strategies, remains the most effective vaccine against bovine tuberculosis. However, BCG vaccination of cattle would require development of diagnostic tests able t...

journal_title：Vaccine

authors： Sopp P,Coad M,Hewinson G,Howard CJ,Cheallaigh CN,Keane J,Harris J,Hope JC

更新日期：2008-10-09 00:00:00

abstract：:Tetanus and diphtheria (Td) antibodies were studied in HIV-1-infected women during puerperium. HIV group (n=61) was compared with Control group (n=101). Twenty-one women from HIV and 13 from Control group who had antibody levels lower than 0.1 IU/mL received a booster with Td vaccine. Antibodies were assessed by doubl...

journal_title：Vaccine

authors： Bonetti TC,Succi RC,Weckx LY,Tavares-Lopes L,de Moraes-Pinto MI

更新日期：2004-09-09 00:00:00

abstract：:Pneumococcal type 1 pilus proteins have been proposed as potential vaccine candidates. Following conjugate pneumococcal vaccination, the prevalence of the pneumococcal type 1 pilus declined dramatically, a decline associated with the elimination of vaccine-type (VT) strains. Here we show that between 2004 and 2007, th...

journal_title：Vaccine

authors： Regev-Yochay G,Hanage WP,Trzcinski K,Rifas-Shiman SL,Lee G,Bessolo A,Huang SS,Pelton SI,McAdam AJ,Finkelstein JA,Lipsitch M,Malley R

更新日期：2010-07-05 00:00:00

abstract：:Vaccine effects of in vivo gene-vaccinated skin graft were evaluated against Toxoplasma gondii (T. gondii) infection. By using a gene gun, cDNA coding T. gondii SAG1 molecule was intracutaneously vaccinated into C57BL/6 (B6; a susceptible strain), BALB/c (a resistant strain) and (C57BL/6 x BALB/c) F1 (CBF1) mice, and ...

journal_title：Vaccine

authors： Saito S,Aosai F,Rikihisa N,Mun HS,Norose K,Chen M,Kuroki T,Asano T,Ochiai T,Hata H,Ichinose M,Yano A

更新日期：2001-02-28 00:00:00

abstract：:A 33-mer peptide of the alpha-gliadin component of gluten was recently identified as primary initiator of the inflammatory response to gluten in coeliac disease (CD) patients. This proline-glutamine-rich peptide (PG-peptide) is highly homologous to internal sequence of pertactin, an immunogenic protein of Bordetella p...

journal_title：Vaccine

authors： He Q,Viljanen MK,Hinkkanen AE,Arvilommi H,Mertsola J,Viander M

更新日期：2005-05-09 00:00:00