Abstract：
:Elevated plasma concentrations of lipoprotein(a) (Lp[a]) are an emerging risk factor for the development of coronary heart disease (CHD). Recent genetic and epidemiologic data have provided strong evidence for a causal role of Lp(a) in CHD. Despite these developments, which have attracted increasing interest from clinicians and basic scientists, many unanswered questions persist. The true pathogenic mechanism of Lp(a) remains a mystery. Significant uncertainty exists concerning the appropriate use of Lp(a) in the clinical setting. No therapeutic intervention remains that can specifically lower plasma Lp(a) concentrations, although the list of compounds that lower Lp(a) and LDL continues to expand.
journal_name
Endocrinol Metab Clin North Amjournal_title
Endocrinology and metabolism clinics of North Americaauthors
Koschinsky ML,Boffa MBdoi
10.1016/j.ecl.2014.08.002subject
Has Abstractpub_date
2014-12-01 00:00:00pages
949-62issue
4eissn
0889-8529issn
1558-4410pii
S0889-8529(14)00071-1journal_volume
43pub_type
杂志文章,评审abstract：:Surgical intervention is a necessary part of a multimodal approach to pituitary lesions. This article summarizes the surgical approach to different neoplastic processes affecting the sellar region. ...
journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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doi：
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
pub_type： 杂志文章,评审
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