Atrial natriuretic factor receptors.

Abstract:

:All of the actions of atrial natriuretic factor (ANF) can be explained on the basis of ANF's interaction with specific receptors on the plasma membrane of cells in target tissues. These receptors have been identified. Binding to these receptors by ANF is time dependent and specific and occurs with high affinity. Numerous analogues of ANF have been synthesized, and in general, their affinity for ANF receptors corresponds closely to their potency in vitro and in vivo. Considerable progress has been made in physicochemically characterizing ANF receptors by photoaffinity labeling and affinity cross-linking techniques.

authors

Jacobs JW,Vlasuk GP,Rosenblatt M

subject

Has Abstract

pub_date

1987-03-01 00:00:00

pages

63-77

issue

1

eissn

0889-8529

issn

1558-4410

journal_volume

16

pub_type

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