Abstract:
:The reasons why women and men are treated with different antihypertensive drugs are not clear. Whether socioeconomic factors influence prescription patterns and blood pressure control differently in women and men has not been investigated. This cross-sectional study performed in a cohort of hypertensive patients from the Swedish Primary Care Cardiovascular Database (SPCCD) examined the influence of educational level, country of birth, gender and concomitant psychiatric disorder on prescription pattern and blood pressure control in 40,825 hypertensive patients. Men were more often than women treated with calcium channel blocker and angiotensin-converting enzyme inhibitor (ACEI), irrespective of education, country of birth and psychiatric disorder. Educational level influenced the prescription pattern to some extent, where the gender differences were reduced in patients with a higher educational level. In women, but not in men, high educational level and concomitant psychiatric disorder were associated with a higher proportion reaching target blood pressure. The predominant use of ACEI and calcium channel blockers in men is not influenced by educational level, country of birth or psychiatric disorder. Thus other explanations must be considered such as gender differences in side effects. Educational level seems to have a greater impact on reaching target blood pressure in women compared with men.
journal_name
J Hum Hypertensjournal_title
Journal of human hypertensionauthors
Ljungman C,Kahan T,Schiöler L,Hjerpe P,Wettermark B,Boström KB,Manhem Kdoi
10.1038/jhh.2014.100subject
Has Abstractpub_date
2015-06-01 00:00:00pages
385-93issue
6eissn
0950-9240issn
1476-5527pii
jhh2014100journal_volume
29pub_type
杂志文章abstract::In the last decades, the prevalence of obesity has increased in the Taiwanese population. This has the potential to impact on the risks of cardiovascular diseases and diabetes. This study investigated trends in the changes in several indices of obesity in the last decade, and the relationship between blood pressure (B...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/jhh.2010.33
更新日期:2011-02-01 00:00:00
abstract::The value of microalbuminuria in predicting hypertensive complications in pregnant patients at high risk was tested in a prospective trial. A total of 276 patients were studied (142 in the study group vs 134 controls). Albumin was measured in 8-h overnight urine collection throughout pregnancy using radioimmunoassay t...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:
更新日期:1996-09-01 00:00:00
abstract::In addition to high blood pressure, hypertension is characterised by metabolic and cardiovascular abnormalities, including decreased arterial compliance. To evaluate arterial involvement in early hypertension, we have employed a technique that analyses the arterial pulse wave contour to separately quantify proximal co...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:
更新日期:1991-10-01 00:00:00
abstract::The assessment of sodium sensitivity requires to measure the difference in mean arterial pressure (MAP) at the end of sodium-loading (SLoad) and sodium-depletion (SDepl) maneuvers with an arm-cuff manometer. Aim of this study is to evaluate whether MAP measuring devices based on the volume-clamp method at the finger c...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/jhh.2014.110
更新日期:2015-07-01 00:00:00
abstract::A random sample of 200 East Anglian general practitioners was surveyed to establish current trends in the management of hypertension, including measurement of blood pressure (BP), patient investigation, treatment and follow-up. A total of 125 (62.5%) completed questionnaires was returned. Responses were used to assess...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:
更新日期:1995-10-01 00:00:00
abstract::The aim of the present paper was to evaluate the influence of a family history of hypertension and the degree of obesity as indicated by tertiles of body mass index on ambulatory blood pressure (BP) values in large number (n = 406) of young mild essential hypertensives. Positive family history of hypertension was asso...
journal_title:Journal of human hypertension
pub_type: 临床试验,杂志文章,多中心研究
doi:
更新日期:1995-07-01 00:00:00
abstract::Early life prevention of obesity and associated metabolic disease is necessary to address the current obesity epidemic. Latino children have a higher risk of obesity, and associated comorbidities such as hypertension than Caucasian children. This study focuses on perinatal childhood and maternal risk factors associate...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/s41371-020-0306-8
更新日期:2020-11-01 00:00:00
abstract::The Chinese Hypertension Intervention Efficacy Study (CHIEF) is a multi-centre randomized controlled clinical trial comparing the effects of amlodipine+angiotensin II receptor blocker and amlodipine+diuretics on the incidence of cardiovascular events, represented as a composite of non-fatal stroke, non-fatal myocardia...
journal_title:Journal of human hypertension
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1038/jhh.2010.45
更新日期:2011-04-01 00:00:00
abstract::Physical exercise can increase urinary albumin excretion rate (UAER) in diabetic patients without microalbuminuria at rest (stage II diabetic nephropathy) or with baseline microalbuminuria (stage III diabetic nephropathy). The aim of this study was to compare the acute effects of captopril, an ACE inhibitor, and nifed...
journal_title:Journal of human hypertension
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1991-06-01 00:00:00
abstract:OBJECTIVE:This study compares the antihypertensive efficacy and tolerability of valsartan, a novel angiotensin II antagonist, given with hydrochlorothiazide (HCTZ) vs placebo or vs valsartan or HCTZ alone. DESIGN:871 adult out-patients with essential hypertension participated in this double-blind study. Patients were ...
journal_title:Journal of human hypertension
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1038/sj.jhh.1000718
更新日期:1998-12-01 00:00:00
abstract::With the introduction of the aldosterone/renin ratio as a screening test, the detection rate of primary aldosteronism has increased considerably. Nevertheless, no consensus has so far been reached regarding the cutoff points, operating characteristics or indeed even the reference values for reporting the aldosterone/r...
journal_title:Journal of human hypertension
pub_type: 杂志文章,评审
doi:10.1038/sj.jhh.1002024
更新日期:2006-07-01 00:00:00
abstract::Persistence in ranks (tracking) for blood pressure and anthropometric measures over a one year period was examined in 208 Nigerian children (age 6-17 years). Systolic blood pressure tracked better than diastolic blood pressure (r = 0.52 to 0.72) and r = 0.25 to 0.55, respectively). For systolic blood pressure, 56.5%-7...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:
更新日期:1992-02-01 00:00:00
abstract::The renin-angiotensin system is central to the pathophysiology of a number of cardiovascular disorders. Most obviously this is so with renin secreting tumours, but the system is of central importance in other disorders such as scleroderma renal crisis and most cases of malignant hypertension. Activation of the renin-a...
journal_title:Journal of human hypertension
pub_type: 杂志文章,评审
doi:10.1038/sj.jhh.1000638
更新日期:1998-05-01 00:00:00
abstract::The aim of this study was to ascertain the relationship between social network and the appearance of mortality (cardiovascular events (CVEs)) in patients with arterial hypertension (AHT). This is a cohort study of 236 patients with a 9-year follow-up. Measurements included age, sex, blood pressure (BP), diabetes, hype...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/jhh.2014.116
更新日期:2015-07-01 00:00:00
abstract::The Guangzhou Biobank Cohort Study (GBCS, n=30 519, age >or=50 years) was established to examine the effects of genetic and environmental influences on health problems and chronic disease development. Guangzhou is undergoing massive economic development, but from a baseline that had remained unchanged for millennia. T...
journal_title:Journal of human hypertension
pub_type: 杂志文章,多中心研究
doi:10.1038/jhh.2009.52
更新日期:2010-02-01 00:00:00
abstract::We have studied prospectively the acute blood pressure lowering effect on an oral dose of captopril, 25 mg in 240 hypertensive patients. The mean relative reduction of systolic and diastolic BP was 16 and 15% respectively and the mean time to the mean arterial pressure nadir was 59 minutes. Systolic BP fell by more th...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:
更新日期:1992-06-01 00:00:00
abstract::Cardiovascular risk is subject to circadian variation, with peak morning incidence of myocardial infarction and stroke correlating with the early morning blood pressure (BP) surge (EMBPS). Ideally, antihypertensive therapy should maintain control of BP throughout the 24-h dosing cycle. In two sister studies, Prospecti...
journal_title:Journal of human hypertension
pub_type: 杂志文章,随机对照试验
doi:10.1038/jhh.2009.4
更新日期:2009-09-01 00:00:00
abstract::Nineteen patients with essential hypertension on regular treatment with nifedipine tablets 20 mg twice daily and whose DBP was < 95 mmHg on at least two occasions two weeks apart were entered in a double-blind randomised crossover study of three weeks treatment with nifedipine coat core (new formulation) either as 30 ...
journal_title:Journal of human hypertension
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1994-04-01 00:00:00
abstract::A genetic risk score (GRS) based on 29 single nucleotide polymorpysms (SNPs) associated with high blood pressure (BP) was prospectively associated with development of hypertension, stroke and cardiovascular events. The aim of the present study was to evaluate the impact of this GRS on the incidence of aortic disease, ...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/s41371-018-0159-6
更新日期:2019-09-01 00:00:00
abstract::Prevalence, awareness, treatment and control of hypertension were assessed in 1032 (90%) of 1147 elderly (> or = 65 years) inhabitants of three Italian villages. Blood pressure (BP) was measured at home on two separate occasions following a standardised protocol. Persons taking antihypertensive drugs or with BP values...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/sj.jhh.1001117
更新日期:2000-12-01 00:00:00
abstract::Despite the association of childhood blood pressure (BP) with hypertension later in the life course, there remains dearth of information regarding the prevalence and emergence of hypertension in children, especially in China. To investigate the current status of BP, prevalence of elevated BP and related factors in Chi...
journal_title:Journal of human hypertension
pub_type: 杂志文章,多中心研究
doi:10.1038/jhh.2015.104
更新日期:2016-04-01 00:00:00
abstract::The last decade has seen the publication of different editions of guidelines for the pharmacological treatment of hypertension that were based on the results of large, randomised trials. Since these guidelines were meant to inform practitioners, we analysed the pattern of prescription of antihypertensive agents betwee...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/sj.jhh.1001176
更新日期:2001-05-01 00:00:00
abstract::Blood pressure-to-height ratio (BPHR) has been reported to perform well for identifying hypertension (HTN) in adolescents but not in young children. Our study was aimed to evaluate the performance of BPHR and modified BPHR (MBPHR) for screening HTN in children. A total of 5268 Chinese children (boys: 53.1%) aged 6-12 ...
journal_title:Journal of human hypertension
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1038/s41371-018-0056-z
更新日期:2018-06-01 00:00:00
abstract::To evaluate ethnic differences in cerebral circulation, an index of carotid vascular resistance (RI) was determined by continuous wave Doppler ultrasound. Validation of the index resulted from a significant correlation between RI and carotid vascular resistance obtained from direct measurement of blood pressure and ca...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:
更新日期:1990-06-01 00:00:00
abstract::The objective of this study was to examine the effect of angiotensin II (Ang II) and angiotensin II type 1 (AT(1)) receptor blockade on pulse wave velocity (PWV) in healthy humans. We studied nine young male volunteers in a double-blind randomised crossover design. Carotid-femoral PWV (an index of arterial stiffness) ...
journal_title:Journal of human hypertension
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.jhh.1001372
更新日期:2002-04-01 00:00:00
abstract::A Holter BP monitor and a noninvasive, continuous cardiac output (CO) monitor were concurrently attached to 25 middle-aged hospitalized patients with essential hypertension (EH). Blood pressure, heart rate (HR) and CO were measured every 10 minutes over 24 hours. Circadian variation of mean BP was studied. Comparison ...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:
更新日期:1990-08-01 00:00:00
abstract::There is growing evidence that hypertension, one of the major modifiable risk factors for cardiovascular disease (CVD), is established early in life. Given this, it is important to discover when hypertension first becomes apparent. Further, it is of particular importance to examine the ethnic differences in blood pres...
journal_title:Journal of human hypertension
pub_type: 杂志文章,评审
doi:10.1038/sj.jhh.1001674
更新日期:2004-04-01 00:00:00
abstract::Older age and low socio-economic conditions are associated with poor control of cardiovascular risk factors (RFs). We assessed the prevalence and awareness of cardiovascular RFs in 503 elderly outpatients of low social status attending two public Internal Medicine clinics in Naples, and studied the interaction of educ...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/sj.jhh.1002098
更新日期:2007-01-01 00:00:00
abstract::There are complications in diagnosing hypertension in children and adolescents due to variation of blood pressure (BP) values to age, gender and height. This study was aimed at assessing whether the performance of BP-to-height ratio (BPHR) can be an effective tool for screening prehypertension and hypertension in Elli...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/jhh.2017.25
更新日期:2017-09-01 00:00:00
abstract::The 2017 American Academy of Pediatrics (AAP) guideline for assessing "elevated blood pressure (BP) (90th BP percentile)" and "high BP (95th BP percentile)" includes a large number of BP cut-offs based on sex, age and height, which makes it cumbersome to use in clinical practice. We developed and evaluated the perform...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/s41371-018-0128-0
更新日期:2019-03-01 00:00:00