Abstract：
:The value of microalbuminuria in predicting hypertensive complications in pregnant patients at high risk was tested in a prospective trial. A total of 276 patients were studied (142 in the study group vs 134 controls). Albumin was measured in 8-h overnight urine collection throughout pregnancy using radioimmunoassay technique. The pregnant women, in both the study and control groups demonstrated a statistically significant increase in albumin excretion rate in the second and third trimester compared with the first. Using logistic and linear regression models, the presence of microalbuminuria in the early third trimester was proven to be predictive of severe disease (odds ratio 2.1, confidence interval (CI) 1.26-3.53) and birth weight (R2 = 0.7, P < 0.05) in the study group. Intrauterine growth retardation and neonatal outcome were less predictable. With the introduction of radioimmunoassays, we believe severe disease can be predicted by detecting microalbuminuria in the early third trimester of pregnancy in high risk patients.
journal_name
J Hum Hypertensjournal_title
Journal of human hypertensionauthors
Bar J,Friedman S,Erman A,Kaplan B,Hod M,Boner G,Ovadia Jsubject
Has Abstractpub_date
1996-09-01 00:00:00pages
S111-4eissn
0950-9240issn
1476-5527journal_volume
10 Suppl 3pub_type
杂志文章abstract：:Dopamine is a natriuretic hormone which is synthesised within the kidney. We have previously found that some ethnic groups (e.g. British Caucasians and Thais) show strong positive correlations between 24 h urinary sodium and dopamine outputs. However no such relationship was found in Iranians and black West Africans. ...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：
更新日期：1990-04-01 00:00:00
abstract：:The aim of this study is to investigate how the blood pressure (BP) circadian rhythm (CR) is influenced by life style. Two groups of subjects were recruited from Nepal and Japan because of the extremely different occupational routines of these countries. The Nepalese represent a rural culture, while the Japanese refle...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：
更新日期：1996-05-01 00:00:00
abstract：:The commonly used methods of estimating the 24-h urinary sodium (UNa) and urinary potassium (UK) from spot urine (SU) are the Kawasaki method (K-method), INTERSALT method (I-method), and Tanaka method (T-method), but the method that is suitable for use in the general Chinese population is still uncertain. We aimed to ...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/s41371-019-0274-z
更新日期：2020-02-01 00:00:00
abstract：:For nearly two decades, the National High Blood Pressure Education Programme has administered a programme of public, patient, and professional education in an effort to reduce uncontrolled hypertension, an important public health problem in the USA. A broad network has been established and many partners have joined fo...
journal_title：Journal of human hypertension
pub_type： 杂志文章,评审
doi：
更新日期：1992-12-01 00:00:00
abstract：:The aim of this study was to evaluate the effect of antihypertensive treatment with doxazosin on left ventricular anatomy and function. Therefore, after 4 weeks of washout with placebo (phase 1), doxazosin (dosage range from 1 to 16 mg, plus hydrochlorothiazide when necessary) was given to 11 essential hypertensive pa...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：
更新日期：1992-02-01 00:00:00
abstract：:To assess vascular compliance in patients with antiphospholipid syndrome (APS), or antiphospholipid antibodies (aPLs) positivity in comparison to healthy people and diabetes mellitus patients. Twenty-five patients with APS or aPLs, 33 healthy people (HP), 28 patients with diabetes mellitus (DM) underwent pulse wave an...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/sj.jhh.1002020
更新日期：2006-07-01 00:00:00
abstract：:The effects of propranolol and diltiazem on left ventricular systolic and diastolic function in hypertensive subjects (DBP 90-114 mmHg) were examined with M-mode and 2D echocardiograms in 21 patients in a double-blind fashion prior to and after 4 months of treatment. Systolic function was assessed by measurement of fr...
journal_title：Journal of human hypertension
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1990-12-01 00:00:00
abstract：:The role of the direct renin inhibitor aliskiren in hypertension is not fully established and use of aliskiren in diabetic patients is especially controversial. A systematic review investigating both short-term diastolic and systolic blood pressure (DBP and SBP) reduction and long-term cardiovascular outcomes has not ...
journal_title：Journal of human hypertension
pub_type： 杂志文章,meta分析
doi：10.1038/s41371-018-0149-8
更新日期：2019-11-01 00:00:00
abstract：:Hypertension is a known risk factor in the genesis of coronary artery disease. However, the effect of pre-existing hypertension on the long-term mortality in patients with established coronary heart disease is not clear. The present cohort study analysed the influence of baseline mild to moderate treated hypertension ...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：
更新日期：1992-08-01 00:00:00
abstract：:Evidence from the medical literature is reviewed to indicate that ambulatory monitoring of blood pressure (ABPM) is a better predictor of target organ damage and clinical outcome in the hypertensive patient than clinic measurements of blood pressure (BP). A re-analysis of the documented BPs from the placebo limb of th...
journal_title：Journal of human hypertension
pub_type： 杂志文章,评审
doi：
更新日期：1995-06-01 00:00:00
abstract：:Both trandolapril and verapamil are effective and widely used antihypertensive agents. The aim of this study was to estimate the efficacy and tolerability of trandolapril/verapamil (Tr/Ve) combination for blood pressure control and renoprotection. PubMed, EMBASE and Cochrane Library were searched for relevant studies....
journal_title：Journal of human hypertension
pub_type： 杂志文章,meta分析
doi：10.1038/jhh.2010.60
更新日期：2011-03-01 00:00:00
abstract：:The kinetic properties of sodium-proton exchange are abnormal in human red blood cells of hypertensive patients and it has been demonstrated that the transport protein undergoes post-translational modifications able to affect its kinetic properties. Protein kinase C (PKC) activation decreases the affinity constant for...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/sj.jhh.1000804
更新日期：1999-05-01 00:00:00
abstract：:Determining blood pressure (BP) values at different daily time periods is a well recognised measure to assess the risk of end-organ damage. However, the use of various definitions of these periods, eg, day vs night, sleep vs wake or arbitrary definitions, makes clinical decisions based on available data difficult. In ...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/sj.jhh.1000910
更新日期：1999-11-01 00:00:00
abstract：:The balance of evidence from animal studies, clinical observations, human experimental studies, and epidemiological studies favours a causal association between sodium and blood pressure. INTERSALT is the largest and most comprehensive study yet published on the sodium-blood pressure relationship, and its significant ...
journal_title：Journal of human hypertension
pub_type： 杂志文章,评审
doi：
更新日期：1989-10-01 00:00:00
abstract：OBJECTIVE:This study compares the antihypertensive efficacy and tolerability of valsartan, a novel angiotensin II antagonist, given with hydrochlorothiazide (HCTZ) vs placebo or vs valsartan or HCTZ alone. DESIGN:871 adult out-patients with essential hypertension participated in this double-blind study. Patients were ...
journal_title：Journal of human hypertension
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1038/sj.jhh.1000718
更新日期：1998-12-01 00:00:00
abstract：:Non-modulating is a highly reproducible type of sodium-sensitive hypertension. The aim of this study was to evaluate in non-modulating individuals the erythrocyte sodium-lithium countertransport (SLC) abnormalities, which have been mentioned as a marker of non-modulation, and the association with increased microalbumi...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/sj.jhh.1001358
更新日期：2002-03-01 00:00:00
abstract：:The aim of the present study was to evaluate effects of long-term treatment with rilmenidine compared with atenolol on lipid and glucose metabolism and cardiovascular remodelling in hypertension. In total, 37 patients with hypertension were randomised to rilmenidine 1-2 mg/day or atenolol 50-100 mg/day for 26 weeks. S...
journal_title：Journal of human hypertension
pub_type： 杂志文章,随机对照试验
doi：10.1038/sj.jhh.1002004
更新日期：2006-06-01 00:00:00
abstract：:miR-33a has been described as a key regulator in the initiation and progression of atherosclerosis. However, its role in arterial hypertension (HTA) has not been elucidated. Therefore, the aim of this study was to determine the association between the expression of miR-33a (5p and 3p) and the carotid intima-media thic...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/s41371-018-0102-x
更新日期：2018-10-01 00:00:00
abstract：:A sodium intervention project was carried out in Tianjin, China, as part of the Tianjin Project, which is a national pilot, community-based intervention programme to reduce non-communicable diseases. The aim of this 3 year sodium project was to evaluate the feasibility and effects of sodium reduction in the population...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：
更新日期：1995-12-01 00:00:00
abstract：:To investigate a possible association between miR-101 and apoptosis of human trophoblast cells mediated by endoplasmic reticulum protein 44 (ERp44) in preeclampsia (PE), we explored the expression of miR-101 in PE placentas (n=30) compared with normotensive pregnant placentas (n=30) and the correlation between miR-101...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/jhh.2014.35
更新日期：2014-10-01 00:00:00
abstract：OBJECTIVE:To assess the association between different antihypertensive drug regimens and plasma lipid levels in the general population. METHODS:The Monitoring Project on Cardiovascular Risk Factors was conducted from 1987 to 1991 as a cross-sectional study in The Netherlands. Antihypertensive drug-users and untreated ...
journal_title：Journal of human hypertension
pub_type： 临床试验,杂志文章
doi：10.1038/sj.jhh.1001197
更新日期：2001-10-01 00:00:00
abstract：:To elucidate whether auscultation of the Korotkoff sounds inside the cuff and in the antecubital fossa leads to different blood pressure (BP) values we measured BP at both sites simultaneously with identical flat stethoscopes in a same-arm test design (part A) in 64 normotensive (N: 32 men, 32 women; mean age: 38.7 +/...
journal_title：Journal of human hypertension
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1038/sj.jhh.1000891
更新日期：1999-10-01 00:00:00
abstract：:Blood pressure (BP) above optimal (< or =120/< or =80 mmHg) is established as a major cardiovascular disease (CVD) risk factor. Prevalence of adverse BP is high in most adult populations; until recently research has been sparse on reasons for this. Since the 1980s, epidemiologic studies confirmed that salt, alcohol in...
journal_title：Journal of human hypertension
pub_type： 杂志文章,评审
doi：10.1038/sj.jhh.1001603
更新日期：2003-09-01 00:00:00
abstract：:High leptin levels are often observed in human obesity and are implicated in obesity-related hypertension. Leptin levels have been found to be higher in hypertensive obese African-American women compared to normotensive African-American women, but a direct association between leptin and blood pressure could not be obt...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/sj.jhh.1001856
更新日期：2005-07-01 00:00:00
abstract：:As the first blood pressure (BP) reference considering influence of height in China, national blood pressure reference for Chinese han children and adolescents aged 7 to 17 years (CCBP) was issued in 2017. The current study aimed to observe the short-term trends in BP and prevalence of high blood pressure (HBP) and hi...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/s41371-019-0183-1
更新日期：2019-05-01 00:00:00
abstract：:The aim of this preliminary study was to determine whether young offspring of first cousin hypertensive parent(s), have higher blood pressure (BP) reactivity in response to their first BP measurement, as compared to the offspring of first cousin normotensive parents. The BP of 135 boys aged 9-10 years was measured, fo...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/sj.jhh.1001284
更新日期：2001-12-01 00:00:00
abstract：:Hypertension is a serious public health threat worldwide. This study sought to explore gaps in urban Chinese adults' awareness and control of hypertension. A cross-sectional study was carried out in eight Chinese cities in 2016. Participants were organized into four groups on the basis of blood pressure (BP) and self-...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/s41371-018-0059-9
更新日期：2018-06-01 00:00:00
abstract：:The aim of the study is to determine the prevalence of hypertension (HTN) and its risk factors in urban and rural India. In Phase I of the Indian Council of Medical Research-India Diabetes (ICMR-INDIAB) study, individuals aged ⩾20 years were surveyed using a stratified multistage sampling design, in three states (Tami...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/jhh.2014.57
更新日期：2015-03-01 00:00:00
abstract：:Older age and low socio-economic conditions are associated with poor control of cardiovascular risk factors (RFs). We assessed the prevalence and awareness of cardiovascular RFs in 503 elderly outpatients of low social status attending two public Internal Medicine clinics in Naples, and studied the interaction of educ...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/sj.jhh.1002098
更新日期：2007-01-01 00:00:00
abstract：:Pulmonary edema is a potentially life-threatening complication of preeclampsia, but only few studies have looked at possible risk factors. This study assessed the association between various potential risk factors and the development of pulmonary edema. An age-matched case-control design with hospital records from a t...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/s41371-020-0300-1
更新日期：2020-10-01 00:00:00
