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Mediterranean diet and non-fatal acute myocardial infarction: a case-control study from Italy.

Abstract：

OBJECTIVE:To add epidemiological data on the association of adherence to the Mediterranean diet with non-fatal acute myocardial infarction (AMI) in a Southern European population. DESIGN:Hospital-based case-control study. Conformity to the traditional Mediterranean diet was assessed through a score (i.e. the Mediterranean diet score, MDS) based on nine dietary components (high consumption of vegetables, legumes, fruit and nuts, cereals, and fish and seafood; high ratio of monounsaturated to saturated lipids; low consumption of dairy and meat; and moderate alcohol consumption). The score ranged between 0 (lowest adherence) and 9 (highest adherence). The association of the MDS, or its components, with the risk of AMI was evaluated through multiple logistic regression models, controlling for potential confounding variables. SETTING:The study was conducted in the greater Milan area (Italy) between 1995 and 2003. SUBJECTS:Seven hundred and sixty patients with a first episode of non-fatal AMI and 682 controls. RESULTS:High consumption of vegetables and legumes were inversely associated with non-fatal AMI risk. As compared with MDS<4, the OR of non-fatal AMI were 0.85 (95 % CI 0.65, 1.12) for MDS of 4-5 and 0.55 (95 % CI 0.40, 0.75) for MDS ≥ 6, with a trend in risk (P<0.01). Results were consistent in strata of selected risk factors and an apparently stronger association emerged for individuals with a lower BMI. CONCLUSIONS:The Mediterranean diet is inversely associated with the risk of non-fatal AMI in this Southern European population.

journal_name

Public Health Nutr

journal_title

Public health nutrition

authors

Turati F,Pelucchi C,Galeone C,Praud D,Tavani A,La Vecchia C

doi

10.1017/S1368980014000858

subject

Has Abstract

pub_date

2015-03-01 00:00:00

pages

713-20

issue

4

eissn

1368-9800

issn

1475-2727

pii

S1368980014000858

journal_volume

18

pub_type

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