Structure of the mouse mammary tumor virus: polypeptides and glycoproteins.

abstract：:The kinetics of retroviral DNA and RNA synthesis are parameters vital to understanding viral growth, especially for human immunodeficiency virus (HIV), which encodes several of its own regulatory genes. We have established a single-cycle growth condition for HIV in H9 cells, a human CD4+ lymphocyte line. The full-leng...

journal_title：Journal of virology

authors： Kim SY,Byrn R,Groopman J,Baltimore D

更新日期：1989-09-01 00:00:00

abstract：:The covalent linkage of oncornavirus-specific DNA to chicken DNA was investigated in normal chicken embryo fibroblasts (CEF) and in virus-producing leukemic cells transformed by avian myeloblastosis virus (AMV). The virus-specific sequences present in cellular DNA fractionated by different methods were detected by DNA...

journal_title：Journal of virology

authors： Markham PD,Baluda MA

更新日期：1973-10-01 00:00:00

abstract：:Naked DNA vaccines expressing the prM and E genes of two tick-borne flaviviruses, Russian spring summer encephalitis (RSSE) virus and Central European encephalitis (CEE) virus were evaluated in mice. The vaccines were administered by particle bombardment of DNA-coated gold beads by Accell gene gun inoculation. Two imm...

journal_title：Journal of virology

authors： Schmaljohn C,Vanderzanden L,Bray M,Custer D,Meyer B,Li D,Rossi C,Fuller D,Fuller J,Haynes J,Huggins J

更新日期：1997-12-01 00:00:00

abstract：:The cellular transcription factors Sp1 and NF-kappaB were upregulated shortly after the binding of purified live or UV-inactivated human cytomegalovirus (HCMV) to the cell surface. The rapid time frame of transcription factor induction is similar to that seen in other systems in which cellular factors are induced foll...

journal_title：Journal of virology

authors： Yurochko AD,Hwang ES,Rasmussen L,Keay S,Pereira L,Huang ES

更新日期：1997-07-01 00:00:00

abstract：:Interferon-induced proteins (IFPs) exert multiple functions corresponding to diverse interferon signals. However, the intracellular functions of many IFPs are not fully characterized. Here, we report that IFP35, a member of the IFP family with a molecular mass of 35 kDa, can interact with the bovine Tas (BTas) regulat...

journal_title：Journal of virology

authors： Tan J,Qiao W,Wang J,Xu F,Li Y,Zhou J,Chen Q,Geng Y

更新日期：2008-05-01 00:00:00

abstract：:We have previously demonstrated that the human papillomavirus (HPV) genome replicates effectively in U2OS cells after transfection using electroporation. The transient extrachromosomal replication, stable maintenance, and late amplification of the viral genome could be studied for high- and low-risk mucosal and cutane...

journal_title：Journal of virology

authors： Reinson T,Toots M,Kadaja M,Pipitch R,Allik M,Ustav E,Ustav M

更新日期：2013-01-01 00:00:00

abstract：:The gD, gB, and gH/gL glycoprotein quartet constitutes the basic apparatus for herpes simplex virus (HSV) entry into the cell and fusion. gD serves as a receptor binding glycoprotein and trigger of fusion. The conserved gB and gH/gL execute fusion. Central to understanding HSV entry/fusion has become the dissection of...

journal_title：Journal of virology

authors： Avitabile E,Forghieri C,Campadelli-Fiume G

更新日期：2009-10-01 00:00:00

abstract：:Disulfide bonds reportedly stabilize the capsids of several viruses, including papillomavirus, polyomavirus, and simian virus 40, and have been detected in herpes simplex virus (HSV) capsids. In this study, we show that in mature HSV-1 virions, capsid proteins VP5, VP23, VP19C, UL17, and UL25 participate in covalent c...

journal_title：Journal of virology

authors： Szczepaniak R,Nellissery J,Jadwin JA,Makhov AM,Kosinski A,Conway JF,Weller SK

更新日期：2011-09-01 00:00:00

abstract：:PM2 DNA was prepared with different superhelical densities (sigma) in order to examine the relationship betweenn supercoiling and the occurrence of a region(s) of unpaired bases in this DNA. A previous study showed that CH3HgOH reacts with native superhelical PM2 DNA more rapidly than the nicked form II. This evaluati...

journal_title：Journal of virology

authors： Woodworth-Gutai M,Lebowitz J

更新日期：1976-04-01 00:00:00

abstract：:Different tombusviruses were able to support the replication of either homologous or heterologous defective interfering (DI) RNAs, and those infected plants usually developed typical attenuated symptoms. However, in some helper virus-DI RNA combinations the inoculated plants were necrotized, although they contained a ...

journal_title：Journal of virology

authors： Havelda Z,Szittya G,Burgyán J

更新日期：1998-07-01 00:00:00

abstract：:Hepatitis B virus (HBV) and woolly monkey hepatitis B virus (WMHBV) are primate hepadnaviruses that display restricted tissue and host tropisms. Hepatitis D virus (HDV) particles pseudotyped with HBV and WMHBV envelopes (HBV-HDV and WM-HDV) preferentially infect human and spider monkey hepatocytes, respectively, there...

journal_title：Journal of virology

authors： Barrera A,Guerra B,Notvall L,Lanford RE

更新日期：2005-08-01 00:00:00

abstract：:The parechoviruses differ in many biological properties from other picornaviruses, and their replication strategy is largely unknown. In order to identify the viral RNA replication complex in human parechovirus type 1 (HPEV-1)-infected cells, we located viral protein and RNA in correlation to virus-induced membrane al...

journal_title：Journal of virology

authors： Krogerus C,Egger D,Samuilova O,Hyypiä T,Bienz K

更新日期：2003-08-01 00:00:00

abstract：:Adenoviral RNA sequences synthesized in nuclei isolated during the late phase of productive infection comprise, besides virus-associated, VA, RNA, five major species, ranging in size from approximately 13S to 55S. The latter RNA species is of the length predicted if the major transcriptional unit expressed during the ...

journal_title：Journal of virology

authors： Yang VW,Flint SJ

更新日期：1979-11-01 00:00:00

abstract：:Respiratory syncytial virus (RSV) infection causes substantial morbidity and some deaths in the young and elderly worldwide. There is no safe and effective vaccine available, although it is possible to reduce the hospitalization rate for high-risk children by anti-RSV antibody prophylaxis. RSV has been shown to modify...

journal_title：Journal of virology

authors： Zhang W,Choi Y,Haynes LM,Harcourt JL,Anderson LJ,Jones LP,Tripp RA

更新日期：2010-01-01 00:00:00

abstract：UNLABELLED:T-cell immunoglobulin and mucin domain 1 (TIM-1) and other TIM family members were recently identified as phosphatidylserine (PtdSer)-mediated virus entry-enhancing receptors (PVEERs). These proteins enhance entry of Ebola virus (EBOV) and other viruses by binding PtdSer on the viral envelope, concentrating ...

journal_title：Journal of virology

authors： Moller-Tank S,Albritton LM,Rennert PD,Maury W

更新日期：2014-06-01 00:00:00

abstract：:The 70S RNA of Rous sarcoma virus contains 4S RNAs which serve as primers for the initiation of DNA synthesis in vitro by the RNA-directed DNA polymerase of the virus. We purified these primers in three different ways-by isolation of the covalent complex between primer and nascent DNA, by differential melting of the 7...

journal_title：Journal of virology

authors： Faras AJ,Dahlberg JE,Sawyer RC,Harada F,Taylor JM,Levinson WE,Bishop JM,Goodman HM

更新日期：1974-05-01 00:00:00

abstract：:The human polyomavirus JC virus (JCV) establishes persistent infections in most individuals and is the etiologic agent of progressive multifocal leukoencephalopathy. In this report, we describe the establishment of a soluble cell-free system that is capable of replicating exogenous plasmid DNA containing the JCV origi...

journal_title：Journal of virology

authors： Nesper J,Smith RW,Kautz AR,Sock E,Wegner M,Grummt F,Nasheuer HP

更新日期：1997-10-01 00:00:00

abstract：:Varicella-zoster virus (VZV) encodes within its unique long region a gene product with protein kinase motifs. In a previous study, we demonstrated that immunoprecipitated VZV open reading frame (ORF) 47 protein was associated with a functional protein kinase activity, on the basis of its ability to both autophosphoryl...

journal_title：Journal of virology

authors： Ng TI,Keenan L,Kinchington PR,Grose C

更新日期：1994-03-01 00:00:00

abstract：:Theiler's virus infection of the central nervous system (CNS) induces an immune-mediated demyelinating disease in susceptible mouse strains, such as SJL/J, and serves as a relevant infectious model for human multiple sclerosis. It has been previously suggested that susceptible SJL/J mice do not mount an efficient cyto...

journal_title：Journal of virology

authors： Kang BS,Lyman MA,Kim BS

更新日期：2002-07-01 00:00:00

abstract：:Temperature-sensitive COS cells, clone E540, have been stably transformed at a restrictive temperature with plasmid pVA1, which contains the adenovirus type 5 virus-associated (VA) genes in addition to the Neor marker. Transformed cell clones, named EVA cells, contained adenovirus DNA in an integrated form while grown...

journal_title：Journal of virology

authors： Martínez C,de la Luna S,Peláez F,Lopez-Turiso A,Valcárcel J,de Haro C,Ortín J

更新日期：1989-12-01 00:00:00

abstract：:Most of the viral DNA extracted from simian virus 40 (SV40)-infected African green monkey kidney cells consists of circular molecules about 5.3 kilobases in contour length. However, about 1% of the viral DNA was found to occur as closed circular dimers that appeared to be formed, preferentially, late in infection. The...

journal_title：Journal of virology

authors： Goff SP,Berg P

更新日期：1977-10-01 00:00:00

abstract：:The temperature-sensitive defects of virus mutants isolated from L cells persistently infected with Newcastle disease virus (NDV) were analyzed. Genetic grouping of the mutants by complementation tests was attempted by using several different methods, including yield analysis, RNA synthesis, and heterozygote formation...

journal_title：Journal of virology

authors： Preble OT,Youngner JS

更新日期：1973-09-01 00:00:00

abstract：:Adenovirus type 19 is a major cause of epidemic keratoconjunctivitis, the only ocular adenoviral infection associated with prolonged corneal inflammation. In this study, we investigated the role of phosphoinositide 3-kinase (PI3K) and Akt and their downstream targets in adenovirus infection, and here we report the nov...

journal_title：Journal of virology

authors： Rajala MS,Rajala RV,Astley RA,Butt AL,Chodosh J

更新日期：2005-10-01 00:00:00

abstract：:Although combination therapy allows the suppression of human immunodeficiency virus type 1 (HIV-1) viremia to undetectable levels, eradication has not been achieved because the virus persists in cellular reservoirs, particularly the latent reservoir in resting CD4(+) T lymphocytes. We previously established a simian i...

journal_title：Journal of virology

authors： Shen A,Yang HC,Zhou Y,Chase AJ,Boyer JD,Zhang H,Margolick JB,Zink MC,Clements JE,Siliciano RF

更新日期：2007-02-01 00:00:00

abstract：:To assess the possible role of cytotoxic T lymphocytes (CTLs) in containing the spread of human immunodeficiency virus in acutely infected individuals, the temporal evolution of the virus-specific CD8+ lymphocyte response was defined in simian immunodeficiency virus of macaques (SIVmac)-infected rhesus monkeys. A brie...

journal_title：Journal of virology

authors： Yasutomi Y,Reimann KA,Lord CI,Miller MD,Letvin NL

更新日期：1993-03-01 00:00:00

abstract：:Epstein-Barr virus (EBV) is the first human virus found to encode many microRNAs. It is etiologically linked to nasopharyngeal carcinoma and EBV-associated gastric carcinoma. During the latent infection period, there are only a few EBV proteins expressed, whereas EBV microRNAs, such as the BamHI-A region rightward tra...

journal_title：Journal of virology

authors： Zheng X,Wang J,Wei L,Peng Q,Gao Y,Fu Y,Lu Y,Qin Z,Zhang X,Lu J,Ou C,Li Z,Zhang X,Liu P,Xiong W,Li G,Yan Q,Ma J

更新日期：2018-11-12 00:00:00

abstract：:The hepatitis E virus (HEV), a nonenveloped RNA virus, is the causative agent of hepatitis E. The mode by which HEV attaches to and enters into target cells for productive infection remains unidentified. Open reading frame 2 (ORF2) of HEV encodes its major capsid protein, pORF2, which is likely to have the determinant...

journal_title：Journal of virology

authors： Kalia M,Chandra V,Rahman SA,Sehgal D,Jameel S

更新日期：2009-12-01 00:00:00

abstract：:Transcription and replication signals within the negative-sense genomic RNA of vesicular stomatitis virus (VSV) are located at the 3' terminus. To identify these signals, we have used a transcription- and replication-competent minigenome of VSV to generate a series of deletions spanning the first 47 nucleotides at the...

journal_title：Journal of virology

authors： Li T,Pattnaik AK

更新日期：1999-01-01 00:00:00

abstract：:Human keratinocytes immortalized by full-length or early-region simian virus 40 (SV40) DNA grow in agarose and form tumors in nude mice, in contrast to keratinocytes immortalized by the E6/E7 genes of human papillomaviruses. To determine the molecular basis for this biological difference in growth, we have used the in...

journal_title：Journal of virology

authors： Yuan H,Veldman T,Rundell K,Schlegel R

更新日期：2002-11-01 00:00:00

abstract：:Dengue virus (DENV) is a major global pathogen that causes significant morbidity and mortality in tropical and subtropical areas worldwide. An improved understanding of the regions within the DENV genome and its encoded proteins that are required for the virus replication cycle will expedite the development of urgentl...

journal_title：Journal of virology

authors： Eyre NS,Johnson SM,Eltahla AA,Aloi M,Aloia AL,McDevitt CA,Bull RA,Beard MR

更新日期：2017-11-14 00:00:00