Wild-type gross leukemia virus: classification of soluble antigens (GSA).

Abstract:

:By inhibiting techniques using indirect immunofluorescence tests and indirect immunoelectron microscopy, the G(Gross) soluble antigens (GSA) in the body fluids of AKR and C58 mice, which have a high incidence of spontaneous leukemia, were classified according to the known specificity of G antigens in the murine Gross leukemia system. GSA existing in the plasma of nonleukemic and leukemic AKR mice and in the ascitic fluid of transplanted AKR spontaneous leukemia K36 showed the several specificities corresponding to G cell surface antigens, GCSAa, b, and c, and type-specific and group-specific viral envelope antigens, tsVEA and gsVEA, respectively. However, the plasma of nonleukemic C58 mice lacks GSAc, which can be recognized by the G-typing mouse serum. GSA corresponding to G(IX) antigen was not detected in the body fluids.

journal_name

J Virol

journal_title

Journal of virology

authors

Aoki T,Herberman RB,Johnson PA,Liu M,Sturm MM

doi

10.1128/JVI.10.6.1208-1219.1972

subject

Has Abstract

pub_date

1972-12-01 00:00:00

pages

1208-19

issue

6

eissn

0022-538X

issn

1098-5514

journal_volume

10

pub_type

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