Use of antimicrobial drugs in general hospitals: IV. Infants and children.

Abstract:

:The use of antimicrobial drugs was studied among 933 randomly selected infants and children who were hospitalized in 20 short-stay general hospitals in Pennsylvania. Twenty-two percent of pediatric patients received antimicrobial drugs: 5% of neonates and 57% of patients aged 12 to 18 months. Sixty-eight percent of the 265 antimicrobial courses administered to these children consisted of a penicillin or a penicillin analogue. Ampicillin was the single drug most frequently administered and was given in 32% of all courses. In contrast to the findings in older children, penicillin or penicillin analogues and aminoglycosides were the only antimicrobial drug groups administered to neonataes. Seventy-nine percent of courses were initiated for proved or suspected infections and 17% were initiated to prevent infections associated with surgical or nonsurgical invasive procedures. Cultures were associated with the initiation of 84% of courses among neonates and 39% of courses among children 6 to 9 years of age. This study provides the initial information, from data derived from randomly selected general hospitals, to permit a statement of norms of practice with respect to use of antimicrobial drugs in pediatric populations.

journal_name

Pediatrics

journal_title

Pediatrics

authors

Townsend TR,Shapiro M,Rosner B,Kass EH

subject

Has Abstract

pub_date

1979-11-01 00:00:00

pages

573-8

issue

5

eissn

0031-4005

issn

1098-4275

journal_volume

64

pub_type

杂志文章
  • Assessment of antifungal therapy in an 800-gram infant with candidal arthritis and osteomyelitis.

    abstract::A 720-g premature newborn developed disseminated candidiasis during treatment with systemic antibiotics and total parenteral nutrition through an umbilical arterial catheter. Clinical features were typical for candidal skeletal infection at this age and included warmth and fusiform swelling of the lower extremities to...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Ward RM,Sattler FR,Dalton AS Jr

    更新日期:1983-08-01 00:00:00

  • Subcutaneous fat necrosis after moderate therapeutic hypothermia in neonates.

    abstract::Therapeutic moderate hypothermia in newborns with hypoxic-ischemic encephalopathy is rapidly becoming standard clinical practice. We report here 12 cases of subcutaneous fat necrosis among 1239 cases registered with a national registry of newborns treated with moderate whole-body hypothermia. All the infants suffered ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2010-3508

    authors: Strohm B,Hobson A,Brocklehurst P,Edwards AD,Azzopardi D,UK TOBY Cooling Register.

    更新日期:2011-08-01 00:00:00

  • Relationship between age of ear piercing and keloid formation.

    abstract:OBJECTIVE:Keloids occur commonly after trauma to the skin, with ear piercing being a well-known inciting event. We surveyed 32 patients with keloids resulting from ear piercing, to examine a potential relationship between age of piercing and keloid formation. METHODS:A total of 32 consecutive patients completed a surv...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2004-1085

    authors: Lane JE,Waller JL,Davis LS

    更新日期:2005-05-01 00:00:00

  • Enuresis: a contrast of attitudes of parents and physicians.

    abstract::Questionnaires were used to survey 1,435 parents and 446 physicians in order to determine and compare attitudes and beliefs about enuresis. Although both groups thought that bed-wetting is a maturational problem, the parent group thought emotional causes were important and were less likely to accept small bladder size...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Shelov SP,Gundy J,Weiss JC,McIntire MS,Olness K,Staub HP,Jones DJ,Haque M,Ellerstein NS,Heagarty MC,Starfield B

    更新日期:1981-05-01 00:00:00

  • The hair collar sign: marker for cranial dysraphism.

    abstract:OBJECTIVE:To call attention to a cutaneous marker for neural tube closure defects of the scalp, the "hair collar" sign. This finding consists of a ring of long, dark, coarse hair surrounding a midline scalp nodule. METHODS AND RESULTS:Four children with small congenital scalp nodules and the hair collar sign were stud...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Drolet BA,Clowry L Jr,McTigue MK,Esterly NB

    更新日期:1995-08-01 00:00:00

  • A multilevel study of the associations between economic and social context, stage of adolescence, and physical activity and body mass index.

    abstract:OBJECTIVE:Prevention efforts targeting adolescent risk behavior have had limited effectiveness, partly because of the reliance on individual-level interventions that do not consider the context within which behavior occurs. In addition, the role of development has not been well studied regarding its possible moderating...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2006-2089M

    authors: McKay CM,Bell-Ellison BA,Wallace K,Ferron JM

    更新日期:2007-02-01 00:00:00

  • Pulmonary embolism in the pediatric emergency department.

    abstract:OBJECTIVE:To describe patients who present to the pediatric emergency department (PED) and are subsequently diagnosed with pulmonary embolism (PE). METHODS:Electronic medical records from 2003 to 2011 of a tertiary care pediatric health care system was retrospectively reviewed to identify patients <21 years who had a ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2013-0126

    authors: Agha BS,Sturm JJ,Simon HK,Hirsh DA

    更新日期:2013-10-01 00:00:00

  • Parents' perceptions of the psychological and social impact of home monitoring.

    abstract::Self-assessments of 133 parents' (74 families) feelings, perceptions, reactions to stresses, and satisfactions during a period of electronic home monitoring are reported. Data were collected during structured interviews by students in a graduate social work program. Although extreme anxiety was prevalent initially, on...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Cain LP,Kelly DH,Shannon DC

    更新日期:1980-07-01 00:00:00

  • Delivery room decision-making for extremely preterm infants in Sweden.

    abstract:OBJECTIVE:To assess neonatologists' attitudes and practices regarding treatment of extremely preterm infants in the delivery room, particularly in response to parental wishes. STUDY DESIGN:Cross-sectional survey of all neonatologists in Sweden registered with the Swedish Pediatric Society. RESULTS:The response rate w...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2005-1885

    authors: Peerzada JM,Schollin J,Håkansson S

    更新日期:2006-06-01 00:00:00

  • Improving growth of very low birth weight infants in the first 28 days.

    abstract:OBJECTIVE:To increase weight gain in the first 28 days after birth for very low birth weight (VLBW) infants by isolating and sharing meaningful process differences between high- and low-weight-gain centers within a neonatal network. DESIGN/METHODS:We identified weight gain as an important target for improvement in 199...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究

    doi:10.1542/peds.112.1.8

    authors: Bloom BT,Mulligan J,Arnold C,Ellis S,Moffitt S,Rivera A,Kunamneni S,Thomas P,Clark RH,Peabody J

    更新日期:2003-07-01 00:00:00

  • Comparison of perinatal outcomes among TennCare managed care organizations.

    abstract:OBJECTIVE:To compare perinatal outcomes among the managed care organizations (MCOs) providing care to beneficiaries enrolled in TennCare, Tennessee's capitated Medicaid managed care program. DESIGN:Retrospective cohort analysis. SUBJECTS:Infants born in Tennessee during 1995 to women enrolled in TennCare. PRIMARY OU...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.104.3.525

    authors: Cooper WO,Hickson GB,Mitchel EF Jr,Ray WA

    更新日期:1999-09-01 00:00:00

  • Asymptomatic Kawasaki Disease in a 3-Month-Old Infant.

    abstract::Kawasaki disease (KD) is the leading cause of acquired heart disease in children in the United States. It is a systemic vasculitis characterized by diffuse inflammation of medium and small blood vessels. If untreated it can lead to myocardial infarction, ischemic heart disease, or sudden death. Early recognition and t...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2015-3936

    authors: Pinches H,Dobbins K,Cantrell S,May J,Lopreiato J

    更新日期:2016-08-01 00:00:00

  • Prepubertal female genitalia: examination for evidence of sexual abuse.

    abstract::Experience with more than 375 cases of possible sexual abuse has taught us that much work still needs to be done in understanding normal prepubertal female anatomy and interpreting findings in sexual abuse cases. Because pediatric clinicians are often called upon to assess possible sexual abuse victims, knowledge of w...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Herman-Giddens ME,Frothingham TE

    更新日期:1987-08-01 00:00:00

  • Surfactant replacement therapy for respiratory distress syndrome. American Academy of Pediatrics. Committee on Fetus and Newborn.

    abstract::Respiratory failure secondary to surfactant deficiency is a major cause of morbidity and mortality in low birth weight immature infants. Surfactant therapy substantially reduces mortality and respiratory morbidity for this population. The statement summarizes the indications for surfactant replacement therapy. Because...

    journal_title:Pediatrics

    pub_type: 指南,杂志文章,实务指引

    doi:

    authors:

    更新日期:1999-03-01 00:00:00

  • Toxicity of over-the-counter cough and cold medications.

    abstract::Over-the-counter (OTC) cough and cold medications are marketed widely for relief of common cold symptoms, and yet studies have failed to demonstrate a benefit of these medications for young children. In addition, OTC medications can be associated with significant morbidity and even mortality in both acute overdoses an...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.108.3.e52

    authors: Gunn VL,Taha SH,Liebelt EL,Serwint JR

    更新日期:2001-09-01 00:00:00

  • Successful treatment of type 1 diabetes and seizures with combined ketogenic diet and insulin.

    abstract::Diabetic ketoacidosis (DKA) is a life-threatening condition and a major cause of morbidity and mortality in children with type 1 diabetes mellitus. The deficiency of insulin leads to metabolic decompensation, causing hyperglycemia and ketosis that resolves with the administration of insulin and fluids. However, an ind...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2011-0741

    authors: Aguirre Castaneda RL,Mack KJ,Lteif A

    更新日期:2012-02-01 00:00:00

  • Effects of acutely increasing systemic vascular resistance on oxygen tension in tetralogy of Fallot.

    abstract::Effects of phenylephrine hydrochloride on the degree of hypoxia were studied in six cyanotic patients with tetralogy of Fallot. Baseline aortic and right atrial oxygen saturations, blood gas tensions, pH, and indicator-dilution curves were obtained under stable conditions. Phenylephrine was infused while systemic arte...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Nudel DB,Berman MA,Talner NS

    更新日期:1976-08-01 00:00:00

  • High-Expenditure Pharmaceutical Use Among Children in Medicaid.

    abstract:BACKGROUND AND OBJECTIVES:Medication use may be a target for quality improvement, cost containment, and research. We aimed to identify medication classes associated with the highest expenditures among pediatric Medicaid enrollees and to characterize the demographic, clinical, and health service use of children prescrib...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2017-1095

    authors: Cohen E,Hall M,Lopert R,Bruen B,Chamberlain LJ,Bardach N,Gedney J,Zima BT,Berry JG

    更新日期:2017-09-01 00:00:00

  • Rotavirus vaccination and intussusception: can we decrease temporally associated background cases of intussusception by restricting the vaccination schedule?

    abstract:OBJECTIVE:The first rotavirus vaccine that was licensed in the United States, RotaShield, could have prevented the enormous burden of rotavirus diarrhea in American children but left instead the unfortunate legacy that live oral rotavirus vaccines may be associated with a serious but rare adverse event: intussusception...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2005-2874

    authors: Tai JH,Curns AT,Parashar UD,Bresee JS,Glass RI

    更新日期:2006-08-01 00:00:00

  • Longstanding obliterative panarteritis in Kawasaki disease: lack of cyclosporin A effect.

    abstract::Kawasaki disease is a childhood vasculitis of medium-sized vessels, affecting the coronary arteries in particular. We have treated a therapy-resistant child who met all diagnostic criteria for Kawasaki disease. After the boy was given intravenous immunoglobulins and salicylates, as well as several courses of pulsed me...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:10.1542/peds.112.4.986

    authors: Kuijpers TW,Biezeveld M,Achterhuis A,Kuipers I,Lam J,Hack CE,Becker AE,van der Wal AC

    更新日期:2003-10-01 00:00:00

  • Noninitiation or withdrawal of intensive care for high-risk newborns.

    abstract::Advances in medical technology have led to dilemmas in initiation and withdrawal of intensive care of newborn infants with a very poor prognosis. Physicians and parents together must make difficult decisions guided by their understanding of the child's best interest. The foundation for these decisions consists of seve...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2006-3180

    authors: American Academy of Pediatrics Committee on Fetus and Newborn.,Bell EF

    更新日期:2007-02-01 00:00:00

  • Unilateral hearing loss is associated with worse speech-language scores in children.

    abstract:OBJECTIVE:To determine whether children with unilateral hearing loss (UHL) demonstrate worse language skills than their siblings with normal hearing, and whether children with UHL are more likely to receive extra assistance at school. PATIENTS AND METHODS:We conducted a case-control study of 6- to 12-year-old children...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2009-2448

    authors: Lieu JE,Tye-Murray N,Karzon RK,Piccirillo JF

    更新日期:2010-06-01 00:00:00

  • Prolonged episodes of hypoxemia in preterm infants undetectable by cardiorespiratory monitors.

    abstract:OBJECTIVE:To determine whether episodes of prolonged hypoxemia occur without prolonged apneic pauses (> or = 20 seconds) and without bradycardia (pulse rate, < or = 100 beats per minute) in apparently well preterm infants. METHODS:Long-term recordings of arterial oxygen saturation as measured by pulse oximetry (SpO2),...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Poets CF,Stebbens VA,Richard D,Southall DP

    更新日期:1995-06-01 00:00:00

  • Management of children with sickle cell disease: a comprehensive review of the literature.

    abstract:OBJECTIVE:Sickle cell disease (SCD) affects 70 000 to 100 000 people in the United States, and 2000 infants are born with the disease each year. The purpose of this study was to review the quality of the literature for preventive interventions and treatment of complications for children with SCD to facilitate the use o...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:10.1542/peds.2010-3686

    authors: Kavanagh PL,Sprinz PG,Vinci SR,Bauchner H,Wang CJ

    更新日期:2011-12-01 00:00:00

  • Cerebral oxygenation in preterm infants.

    abstract:BACKGROUND AND OBJECTIVE:Prone sleeping is a major risk factor for sudden infant death syndrome (SIDS) and preterm infants are at significantly increased risk. In term infants, prone sleeping is associated with reduced mean arterial pressure (MAP) and cerebral tissue oxygenation index (TOI). However, little is known ab...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2014-0773

    authors: Fyfe KL,Yiallourou SR,Wong FY,Odoi A,Walker AM,Horne RS

    更新日期:2014-09-01 00:00:00

  • Obesity development during adolescence in a biracial cohort: the NHLBI Growth and Health Study.

    abstract:OBJECTIVE:The National Heart, Lung, and Blood Institute Growth and Health Study (NGHS) is a 10-year study to investigate the development of obesity in black and white girls during adolescence and its environmental and psychosocial correlates. The purpose of this report was to examine changes in the annual prevalence ra...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究

    doi:10.1542/peds.110.5.e54

    authors: Kimm SY,Barton BA,Obarzanek E,McMahon RP,Kronsberg SS,Waclawiw MA,Morrison JA,Schreiber GB,Sabry ZI,Daniels SR,NHLBI Growth and Health Study.

    更新日期:2002-11-01 00:00:00

  • Narrow vs broad-spectrum antimicrobial therapy for children hospitalized with pneumonia.

    abstract:BACKGROUND:The 2011 Pediatric Infectious Diseases Society/Infectious Diseases Society of America community-acquired pneumonia (CAP) guideline recommends narrow-spectrum antimicrobial therapy for most children hospitalized with CAP. However, few studies have assessed the effectiveness of this strategy. METHODS:Using da...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究

    doi:10.1542/peds.2013-1614

    authors: Williams DJ,Hall M,Shah SS,Parikh K,Tyler A,Neuman MI,Hersh AL,Brogan TV,Blaschke AJ,Grijalva CG

    更新日期:2013-11-01 00:00:00

  • Teleintervention for infants and young children who are deaf or hard-of-hearing.

    abstract::Advancements in videoconferencing equipment and Internet-based tools for sharing information have resulted in widespread use of telemedicine for providing health care to people who live in remote areas. Given the limited supply of people trained to provide early-intervention services to infants and young children who ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2010-0354J

    authors: McCarthy M,Muñoz K,White KR

    更新日期:2010-08-01 00:00:00

  • Skin lesions in association with beta-hemolytic Streptococcus group B.

    abstract::A full-term male infant delivered by caesarean section following a prolonged rupture of the amniotic membranes of 30 hours' duration manifested peculiar skin lesions at the time of birth consistent with the healing phase of bullous impetigo. He was colonized with beta-hemolytic Streptococcus group B that was also cult...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Lopez JB,Gross P,Boggs TR

    更新日期:1976-12-01 00:00:00

  • Allowing adolescents and young adults to plan their end-of-life care.

    abstract:OBJECTIVE:The objective of this study was to assess and compare the usefulness, helpfulness, and stress associated with reviewing a previously adapted advance care planning guide, My Thoughts, My Wishes, My Voice, in comparison with the widely used adult document Five Wishes by adolescents and young adults (AYAs) livin...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2012-0663

    authors: Wiener L,Zadeh S,Battles H,Baird K,Ballard E,Osherow J,Pao M

    更新日期:2012-11-01 00:00:00