Abstract:
:Diabetic ketoacidosis (DKA) is a life-threatening condition and a major cause of morbidity and mortality in children with type 1 diabetes mellitus. The deficiency of insulin leads to metabolic decompensation, causing hyperglycemia and ketosis that resolves with the administration of insulin and fluids. However, an induced state of ketosis is the basis for the success of the ketogenic diet (KD), which is an effective therapy for children with intractable epilepsy. We report the case of a 2-year-old girl who presented to the emergency department with 1-week history of decreased activity, polyuria, and decreased oral intake. Her past medical history was remarkable for epilepsy, for which she was started on the KD with a significant improvement. Her laboratory evaluation was compatible with DKA, and fluids and insulin were given until correction. Because of concerns regarding recurrence of her seizures, the KD was resumed along with the simultaneous use of insulin glargine and insulin aspart. Urine ketones were kept in the moderate range to keep the effect of ketosis on seizure control. Under this combined therapy, the patient remained seizure-free with no new episodes of DKA.
journal_name
Pediatricsjournal_title
Pediatricsauthors
Aguirre Castaneda RL,Mack KJ,Lteif Adoi
10.1542/peds.2011-0741subject
Has Abstractpub_date
2012-02-01 00:00:00pages
e511-4issue
2eissn
0031-4005issn
1098-4275pii
peds.2011-0741journal_volume
129pub_type
杂志文章相关文献
PEDIATRICS文献大全abstract:OBJECTIVES:Infants born to immigrant mothers, including Hispanic mothers, display birth weight and mortality advantages, compared with other disadvantaged groups. We examined prenatal biological factors and maternal practices that account for this advantage. Then we estimated the extent to which healthy birth outcomes,...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2009-0496
更新日期:2010-02-01 00:00:00
abstract:OBJECTIVES:To describe national emergency department (ED) trends in computed tomography (CT) and ultrasound imaging for the evaluation of pediatric nontraumatic abdominal pain from 2007 through 2014. METHODS:We used data from the National Hospital Ambulatory Medical Care Survey to measure trends in CT and ultrasound u...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2017-0615
更新日期:2017-10-01 00:00:00
abstract::Survival of motor neuron 1-------negative spinal muscular atrophy (SMA) is heterogeneous and remains a diagnostic challenge. The clinical spectrum continues to expand and ∼33 genes have been identified to date. The present report describes a 9-year-old girl with novel clinical phenotype of a patient with polyarticular...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2016-1068
更新日期:2016-10-01 00:00:00
abstract:OBJECTIVES:Preterm infants are frequently discharged from the hospital growth retarded and show reduced growth throughout childhood. In a large efficacy and safety trial, we tested the hypothesis that nutritional intervention in the first 9 months postterm would reverse postdischarge growth deficits and improve neurode...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1542/peds.108.3.703
更新日期:2001-09-01 00:00:00
abstract:BACKGROUND:Introduction of the heptavalent pneumococcal conjugate vaccine (PCV7) changed the epidemiology of invasive pneumococcal disease (IPD). We evaluated the changes that occurred after PCV7 introduction among Utah infants aged 1 to 90 days, too young to be fully immunized. METHODS:We identified children <18 year...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2012-3900
更新日期:2013-07-01 00:00:00
abstract::A 38-day-old infant had fever, jaundice, hepatosplenomegaly, and a hemolytic anemia. A peripheral blood smear demonstrated intraerythrocytic malarial parasites identified as Plasmodium vivax. Maternal and infant sera contained antibodies to this species. A directed history revealed the mother had suffered several febr...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1977-08-01 00:00:00
abstract::To test the efficacy and safety of vitamin E in preventing retinopathy of prematurity, 287 infants with birth weights of less than 1.5 kg or gestational ages of less than 33 weeks were enrolled within 24 hours of birth in a randomized, double-masked trial of IV, followed by oral, placebo v tocopherol (adjusted to plas...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1987-04-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to use nationwide registries to examine the health of children up to 4 years of age who were born as a result of in vitro fertilization. METHODS:Children born after in vitro fertilization (N = 4559) from 1996 to 1999 were monitored until 2003. Two control groups were selected fr...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2006-0735
更新日期:2006-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:International patterns of antibiotic use and laboratory testing in bronchiolitis in emergency departments are unknown. Our objective is to evaluate variation in the use of antibiotics and nonindicated tests in infants with bronchiolitis in 38 emergency departments in Pediatric Emergency Resear...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2019-3684
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:Adolescent men who have sex with men (AMSM) have a high rate of HIV diagnoses. An estimated 14.5% of HIV infections in the United States are undiagnosed; but among 13- to 24-year-olds, the rate is 51.4%. We describe HIV testing rates and identifies salient individual, family, school, and health care influenc...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2019-2322
更新日期:2020-03-01 00:00:00
abstract::To evaluate the long-term effects of slow-release formulations of theophylline and terbutaline on pulmonary function, clinical symptoms, and side effects, 24 children with stable and moderately severe perennial asthma participated in a prospective double-blind cross-over study. The patients and the treatments were ran...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1989-07-01 00:00:00
abstract:BACKGROUND:Prelicensure studies of diphtheria, tetanus, acellular pertussis, hepatitis B, inactivated polio virus vaccine suggested that there were higher rates of fever after its administration than when its component antigens were given separately. METHODS:We conducted an open, controlled, cohort study to evaluate s...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2008-1977
更新日期:2008-12-01 00:00:00
abstract:OBJECTIVE:To examine the relationship between pulmonary function, nutritional status, body image, and eating attitudes in children with cystic fibrosis (CF) compared with healthy controls. METHOD:Seventy-six children with CF (39 girls) and 153 healthy control children (82 girls) were recruited. All children were betwe...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.107.6.e92
更新日期:2001-06-01 00:00:00
abstract:OBJECTIVES:To develop a practical, readily applied algorithm for primary health care providers to identify, evaluate, and manage constipation in children with autism spectrum disorders (ASDs). METHODS:The Gastroenterology Committee of the Autism Speaks Autism Treatment Network (ATN), a multisite consortium of centers ...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2012-0900H
更新日期:2012-11-01 00:00:00
abstract:INTRODUCTION:4-Aminopyridine (4-AP) is a potassium channel blocker used to increase muscle strength in the treatment of demyelinating diseases such as multiple sclerosis. We describe a case of ingestion by an 8-month-old child that resulted in severe but transient symptoms. CASE REPORT:An 8-month-old boy was found wit...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.111.1.e82
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVE:To examine whether the Safe Environment for Every Kid (SEEK) model of enhanced primary care would improve the attitudes, knowledge, comfort, competence, and behavior of child health care professionals (HPs) regarding addressing major risk factors for child maltreatment (CM). METHODS:In a cluster randomized c...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2010-1845
更新日期:2011-04-01 00:00:00
abstract:OBJECTIVE:To assess whether the adequate antibody response observed in former extremely premature infants after the primary series of immunizations is sustained after the first booster vaccines. SUBJECTS AND METHODS:Sixteen former extremely premature (<29 weeks, <1000 g at birth) and 17 former full-term (>37 weeks) in...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.101.4.597
更新日期:1998-04-01 00:00:00
abstract::Neurologically impaired children have an increased frequency of recurrent pain and irritability that persist in some despite comprehensive evaluation and management of possible pain sources. We hypothesized that visceral hyperalgesia was a source of chronic unexplained irritability and report the outcome of gabapentin...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2006-1609
更新日期:2007-02-01 00:00:00
abstract:OBJECTIVE:Skin involvement in children with acute monocytic leukemia or CD30-positive anaplastic large-cell lymphoma is well-known. In contrast, very little is known about the malignant cutaneous infiltrates in children with acute lymphoblatic leukemia (ALL) or lymphoblastic lymphoma (LBL). This study was designed to d...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1542/peds.100.1.60
更新日期:1997-07-01 00:00:00
abstract:CONTEXT:Breastfeeding duration and exclusivity among Latinas fall below recommended levels, indicating a need for targeted interventions. The effectiveness of clinical breastfeeding interventions for Latinas remains unclear. OBJECTIVE:To systematically review the documented effectiveness of clinical breastfeeding inte...
journal_title:Pediatrics
pub_type: 杂志文章,meta分析,评审
doi:10.1542/peds.2015-2423
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVES:To update clinical practice guidelines to assist primary care (PC) clinicians in the management of adolescent depression. This part of the updated guidelines is used to address practice preparation, identification, assessment, and initial management of adolescent depression in PC settings. METHODS:By using ...
journal_title:Pediatrics
pub_type: 杂志文章,实务指引
doi:10.1542/peds.2017-4081
更新日期:2018-03-01 00:00:00
abstract::We describe here the case of a boy who presented 2 days after birth with purpura fulminans on his feet and scalp. Laboratory investigations revealed signs of disseminated intravascular coagulation. An underlying coagulation disorder was suspected, and therapy with recombinant tissue plasminogen activator, fresh-frozen...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2009-2913
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVE:To determine hepatitis A vaccination coverage and factors associated with not receiving hepatitis A vaccine among children. METHODS:A random cluster sample survey was conducted of parents of children who attended kindergarten in Butte County, California, in 2000. Because of a history of recurrent epidemics, ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.112.4.e269
更新日期:2003-10-01 00:00:00
abstract:BACKGROUND:This is the first peer-reviewed study to quantify diaper need, propose a method to measure diaper need, and explore psychosocial variables associated with diaper need in a large sample of urban, low-income families. METHODS:Data were derived from a cross-sectional study in 877 pregnant and parenting women. ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2013-0597
更新日期:2013-08-01 00:00:00
abstract::Involvement of the optic nerve, either because of inflammation or increased intracranial pressure, is a rare manifestation of Lyme disease. Of the 4 children reported here with optic nerve abnormalities, 2 had decreased vision months after disease onset attributable to optic neuritis, and 1 had headache and diplopia e...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.108.2.477
更新日期:2001-08-01 00:00:00
abstract::A retrospective record review was used to examine utilization of a pediatric walk-in clinic available to an entire urban community and to evaluate the effectiveness of follow-up care for a sample of the users of this facility who receive their regular pediatric care at a local comprehensive child health center. Result...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1980-05-01 00:00:00
abstract:OBJECTIVE:To investigate whether the consumption of a nutrient-enriched formula after hospital discharge determines different growth and weight gain composition in preterm infants according to intra- and extrauterine growth pattern. METHODS:Two hundred seven preterm infants were randomized at term-corrected age to rec...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2012-1193
更新日期:2012-11-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to determine whether learning and school problems in extremely low birth weight (ELBW) and reference children differ between cohorts in different countries. METHODS:Participants were 4 international population-based cohorts of ELBW survivors who were 500 to 1000 g birth weight from ...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1542/peds.112.4.943
更新日期:2003-10-01 00:00:00
abstract:OBJECTIVES:To describe the prevalence and secular trends of high weight-for-length among infants (ages, 3-23 months) in the biennial US Department of Agriculture Women, Infants, and Children Program and Participants Characteristic (WIC-PC) Survey from 2000 through 2014 (n = 16 927 120). METHODS:Weight-for-length was c...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2016-2034
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:By surveying practitioners in our community, we hoped to determine what pediatricians and family physicians (FPs) perceive as barriers to the American Academy of Pediatrics (AAP) Recommendation on Domestic Violence Screening. BACKGROUND:When screened in the pediatric setting, as many as 40% of mothers will d...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.108.1.98
更新日期:2001-07-01 00:00:00