Abstract:
BACKGROUND:Introduction of the heptavalent pneumococcal conjugate vaccine (PCV7) changed the epidemiology of invasive pneumococcal disease (IPD). We evaluated the changes that occurred after PCV7 introduction among Utah infants aged 1 to 90 days, too young to be fully immunized. METHODS:We identified children <18 years with culture-confirmed IPD from 1997-2010. We analyzed demographic, clinical, and serotype data for infants aged 1-90 days. The pre- and post-vaccine introduction periods spanned 1997-2000 and 2001-2010, respectively. RESULTS:Of 513 children with IPD, 36 were 1 to 90 days and accounted for 7% of IPD cases in both the pre- and post-vaccine introduction period. The pre-vaccine IPD incidence rate was 5.0 per 100 000 live births, and was unchanged in the post-vaccine introduction period. IPD caused by PCV7 serotypes decreased by 74% (from 2.2 to 0.58 per 100 000), whereas non-vaccine serotype IPD increased by 57% (from 2.8 to 4.4 per 100 000). Sixteen infants (44%) required intensive care, and 3 (8%) died. Bacteremia without focus (56%) and meningitis (44%) were the predominant syndromes in the pre- and post-vaccine introduction periods, respectively. In the post-vaccine introduction period, serotype 7F was the most common serotype among infants and was responsible for 50% of meningitis. CONCLUSIONS:The incidence of IPD in Utah infants aged 1 to 90 days caused by PCV7 serotypes decreased after PCV7 introduction, but overall incidence was unchanged. In the post-vaccine introduction period, serotype 7F predominated in this age group and was associated with meningitis.
journal_name
Pediatricsjournal_title
Pediatricsauthors
Olarte L,Ampofo K,Stockmann C,Mason EO,Daly JA,Pavia AT,Byington CLdoi
10.1542/peds.2012-3900subject
Has Abstractpub_date
2013-07-01 00:00:00pages
e17-24issue
1eissn
0031-4005issn
1098-4275pii
peds.2012-3900journal_volume
132pub_type
杂志文章相关文献
PEDIATRICS文献大全abstract:BACKGROUND AND OBJECTIVE:Individuals with fragile X syndrome (FXS) are frequently codiagnosed with autism spectrum disorder (ASD). Most of our current knowledge about ASD in FXS comes from family surveys and small studies. The objective of this study was to examine the impact of the ASD diagnosis in a large clinic-base...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1542/peds.2016-1159F
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVE:High rates of use of child safety seats have been achieved. A remaining challenge in child passenger safety is to reach the Healthy People 2010 objective of child safety seat use to 100%. Several factors have been reported to influence child safety seat use. A child safety seat Hassles Scale was developed to ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2005-2211
更新日期:2006-07-01 00:00:00
abstract:OBJECTIVE:This study examined the process of health care transition (HCT) posing the following questions: What are the transition experiences of youths and young adults with disabilities and special health care needs, family members, and health care providers? What are promising practices that facilitate successful HCT...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2004-1321
更新日期:2005-01-01 00:00:00
abstract::Sophisticated modern methods of fetal monitoring during labor have improved the prognosis for high-risk infants, but the possible adverse side effects have not yet been fully documented. One infant with osteomyelitis and one with streptococcal sepsis are reported. In the future, greater attention should be paid to suc...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1975-02-01 00:00:00
abstract:OBJECTIVES:To identify psychosocial factors that place adolescents at risk for participation in tobacco promotions, and to further investigate the hypothesis that psychosocial vulnerabilities have an indirect effect on smoking initiation among youth by way of involvement with tobacco promotions. METHODS:Data were from...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.111.2.402
更新日期:2003-02-01 00:00:00
abstract::The interval from the beginning of the Q wave to the origin of the T wave (Q-oTc interval) and total and ionized serum calcium levels were measured in 27 full-term and 77 premature infants. The correlation between Q-oTc and total and ionized calcium levels was significant in both full-term and normal premature infants...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1978-06-01 00:00:00
abstract:OBJECTIVE:Substance abuse remains one of the major threats to adolescent health in Western cultures. The study aim was to ascertain the extent of association between pubertal development and early adolescent substance use. METHODS:The design was a cross-sectional survey of 10- to 15-year-old subjects in the states of ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2003-0626-F
更新日期:2004-09-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to assess the prevalence and characteristics of medication errors in pediatric and neonatal inpatients and to measure the impact of interventions to reduce medication errors. METHODS:A preintervention and postintervention cross-sectional study was conducted of a sample of pres...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1542/peds.2008-0014
更新日期:2008-09-01 00:00:00
abstract::Abdominal muscle deficiency, urinary tract abnormalities, and cryptorchidism are the three major features of the prune-belly syndrome, also referred to as triad syndrome or Eagle-Barrett syndrome. The etiology is unclear and the pathogenesis a subject of continuing debate. Clinical and pathologic experience with seven...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1984-04-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Physicians have a major influence on parental vaccine decisions. We tested a physician-targeted communication intervention designed to (1) reduce vaccine hesitancy in mothers of infants seen by trained physicians and (2) increase physician confidence in communicating about vaccines. METHODS:W...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2014-3199
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Primary disabilities in children prenatally exposed to alcohol have a major impact on their daily life. It is suggested that these issues persist into adulthood, but few studies have addressed the outcome in adults with prenatal exposure, especially those with fetal alcohol syndrome (FAS). The ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2014-1915
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVES:The goals were to examine factors related to positive Pediatric Symptom Checklist scores in an urban practice and to examine the relative contribution of parental/personal concern about emotional and behavioral problems to mental health problem identification. METHODS:Annual screening using the Pediatric Sy...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2006-0026
更新日期:2006-11-01 00:00:00
abstract:OBJECTIVES:The purpose of this work was to compare the efficacy of propofol, a hypnotic agent, to the regimen of morphine, atropine, and suxamethonium as an induction agent for nonemergency neonatal endotracheal intubation. We hypothesized that propofol aids intubation by allowing the continuation of spontaneous breath...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2006-2708
更新日期:2007-06-01 00:00:00
abstract::The bioavailability and absorption pattern of theophylline from a slow-release theophylline sprinkle preparation were investigated in 12 asthmatic children both in fasting conditions and after a standardized meal. Theophylline given intravenously was used as a reference. Theophylline from the slow-release theophylline...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1984-10-01 00:00:00
abstract:OBJECTIVES:As part of the evaluation of the American Academy of Pediatrics (AAP) Community Access to Child Health (CATCH), to 1) identify, retrospectively, the actual chronology of activities undertaken through CATCH, and 2) review its antecedents within the AAP, and its predecessor program-Healthy Children. METHODS:K...
journal_title:Pediatrics
pub_type: 历史文章,杂志文章
doi:
更新日期:1999-06-01 00:00:00
abstract:OBJECTIVE:To examine the association between sweet drink consumption and overweight among preschool children. METHODS:A retrospective cohort design was used to examine the association between sweet drink consumption and overweight at follow-up among 10904 children who were aged 2 and 3 years and had height, weight, an...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2004-1148
更新日期:2005-02-01 00:00:00
abstract:BACKGROUND:Children with sickle cell anemia (SCA) are at increased risk for invasive pneumococcal disease; antibiotic prophylaxis significantly reduces this risk. We calculated the proportion of children with SCA who received ≥300 days of antibiotic prophylaxis and identified predictors of such receipt. METHODS:Childr...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2017-2182
更新日期:2018-03-01 00:00:00
abstract::The pediatrician plays a key role in the prevention of mother-to-child transmission of HIV-1 infection. For infants born to women with HIV-1 infection identified during pregnancy, the pediatrician ensures that antiretroviral prophylaxis is provided to the infant to decrease the risk of acquiring HIV-1 infection and pr...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2008-3076
更新日期:2009-01-01 00:00:00
abstract::Group B streptococcal colonization of normal newborn infants increased from 22.5% within 20 hours of birth to 65.4% at the time of hospital discharge (P less than .001). In contrast, colonization in mothers did not change significantly between the time of admission to labor and delivery (27.7%) and the time of dischar...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1977-05-01 00:00:00
abstract::Questionnaires were used to survey 1,435 parents and 446 physicians in order to determine and compare attitudes and beliefs about enuresis. Although both groups thought that bed-wetting is a maturational problem, the parent group thought emotional causes were important and were less likely to accept small bladder size...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1981-05-01 00:00:00
abstract:OBJECTIVES:To review the relationship between parent and child literacy and child health outcomes and interventions designed to improve child health outcomes for children or parents with low literacy skills. METHODS:We searched Medline and the Cumulative Index to Nursing and Allied Health Literature (CINAHL) for artic...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2009-1162B
更新日期:2009-11-01 00:00:00
abstract::The proven effectiveness of biologics and other immunomodulatory products in inflammatory rheumatic diseases has resulted in their widespread use as well as reports of potential short- and long-term complications such as infection and malignancy. These complications are especially worrisome in children who often have ...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2013-0755
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVE:To determine the differences or similarities in the clinical presentation between patients with primary and secondary nocturnal enuresis. METHODS:A total of 170 patients with nocturnal enuresis were assessed at a busy tertiary care pediatric voiding dysfunction clinic at the University of Oklahoma Health Sci...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2004-1402
更新日期:2005-04-01 00:00:00
abstract::Developmental dysplasia of the hip (DDH) encompasses a wide spectrum of clinical severity, from mild developmental abnormalities to frank dislocation. Clinical hip instability occurs in 1% to 2% of full-term infants, and up to 15% have hip instability or hip immaturity detectable by imaging studies. Hip dysplasia is t...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2016-3107
更新日期:2016-12-01 00:00:00
abstract::National guidelines for the diagnosis and management of hypertension in children have been available for nearly 40 years. Unfortunately, knowledge and recognition of the problem by clinicians remain poor. Prevalence estimates are highly variable because of differing standards, populations, and blood pressure (BP) meas...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2015-3616
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:To characterize the cardiac effects of dexamethasone in very low birth weight infants. DESIGN:Prospective, randomized, placebo-controlled, double-blind trial. Enrolled subjects were randomized to receive either a 42-day tapering course of dexamethasone or a saline placebo. Echocardiographic measurements were...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1996-06-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Trisomy 21 is known to decrease the risk of several (nonocular) angiogenic-mediated diseases. The objective of this study was to determine whether trisomy 21 can also be shown to be significantly protective against ocular angiogenic-mediated disorders such as retinopathy of prematurity (ROP). ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2015-0623
更新日期:2015-08-01 00:00:00
abstract::This policy statement, which recognizes the large changes in immigrant status since publication of the 2005 statement "Providing Care for Immigrant, Homeless, and Migrant Children," focuses on strategies to support the health of immigrant children, infants, adolescents, and young adults. Homeless children will be addr...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2013-1099
更新日期:2013-06-01 00:00:00
abstract::Idiopathic acute eosinophilic pneumonia is a rare and potentially life-threatening condition that is defined by bilateral pulmonary infiltrates and fever in the presence of pulmonary eosinophilia. It often presents acutely in previously healthy individuals and can be difficult to distinguish from infectious pneumonia....
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2019-3007
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:The relation between smoke exposure in early life, the prenatal period in particular, and the vascular development of young children is largely unknown. METHODS:Data from the birth cohort participating in the WHISTLER-Cardio study were used to relate the smoking of parents during pregnancy to subsequent vas...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2011-0249
更新日期:2012-01-01 00:00:00