Invasive thymoma (a case report).

Abstract:

:A 10-year old Nigerian boy was admitted to hospital with a history of swelling in the neck, change of voice, dysphagia and dyspnoea of 2 weeks duration. He died on the 2nd day of admission. Autopsy revealed a thymoma infiltrating the thyroid, trachea and neck muscles and transforming the tracheal lumen into a slit like space. The condition is considered worthy of record on account of its rarity and of the short clinical course terminating in death. The authors feel that the most important factor in determining the prognosis of thymoma is the presence or absence of gross invasion.

journal_name

Neoplasma

journal_title

Neoplasma

authors

Suseelan AV,Ikerionwu SE,Ojukwu JO

subject

Has Abstract

pub_date

1979-01-01 00:00:00

pages

493-7

issue

4

eissn

0028-2685

issn

1338-4317

journal_volume

26

pub_type

杂志文章
  • Cells producing recombinant retrovirus with thymidine kinase gene from Herpes simplex virus suitable for human cancer gene therapy.

    abstract::Therapeutic cells producing amphotropic retrovirus, which are able to transduce in vivo thymidine kinase gene of Herpes simplex virus were prepared. Single-cell clone cells with high virus productivity (PA-3 17JH5c113) were obtained by cell cloning. The cells were found free of replication competent retrovirus, they w...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:

    authors: Hlavatý J,Hlubinová K,Bies J,Altaner C

    更新日期:1999-01-01 00:00:00

  • Retrospective analysis of efficacy of trastuzumab in adjuvant treatment of HER 2 positive early breast cancer - single institution experience.

    abstract::Addition of trastuzumab to chemotherapy is the cornerstone of adjuvant treatment of early HER2 positive breast cancer. Clinical trials and metaanalyses of adjuvant trastuzumab have shown significant reduction in risk of recurrence and death. Nevertheless, the real magnitude of the effect of any drug must be reevaluate...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:10.4149/neo_2016_513

    authors: Ban M,Viculin J,Tomic S,Capkun V,Strikic A,Mise BP,Utrobicic I,Vrdoljak E

    更新日期:2016-01-01 00:00:00

  • The FBXW7 tumor suppressor inhibits breast cancer proliferation and promotes apoptosis by targeting MTDH for degradation.

    abstract::Metadherin (MTDH) is an oncoprotein and is expressed at high levels in a wide variety of human carcinomas, which represents an important genetic determinant and regulates multiple events in tumorigenesis. MTDH promotes breast cancer cell proliferation and tumorigenesis through the activation of numerous signaling path...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:10.4149/neo_2018_170228N149

    authors: Chen X,Li XY,Long M,Wang X,Gao ZW,Cui Y,Ren J,Zhang Z,Liu C,Dong K,Zhang H

    更新日期:2018-01-01 00:00:00

  • Granulocyte colony-stimulating factor demonstrates antitumor activity in melanoma model in mice.

    abstract::Granulocyte colony-stimulating factor (G-CSF) was found to exert antitumor activity against murine MmB16 melanoma when administered intratumorally. However, subcutaneous administration of this cytokine at a site distant from the growing tumor did not show any antitumor effects. G-CSF did not influence the proliferativ...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:

    authors: Gołab J,Zagozdzon R,Stokłosa T,Kaca A,Dabrowska A,Giermasz A,Feleszko W,Jakóbisiak M

    更新日期:1998-01-01 00:00:00

  • Cigarette smoking extract causes hypermethylation and inactivation of WWOX gene in T-24 human bladder cancer cells.

    abstract::Genomic, epigenetic and expression alterations of WW domain containing oxidoreductase (WWOX) have been implicated in multiple tumor types. The current study was designed to examine the expression of WWOX in tumor tissues of human bladder transitional cell carcinoma (BTCC) and the influence of cigarette smoke extract (...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:10.4149/neo_2012_028

    authors: Yang W,Cui S,Ma J,Lu Q,Kong C,Liu T,Sun Z

    更新日期:2012-01-01 00:00:00

  • Association among an autocrine parameter (EGF-R) and endocrine parameters (ER and PR) in locoregional breast cancer.

    abstract::Sixty-three locoregional breast cancer biopsies were examined for association among epidermal growth factor receptors (as parameter of autocrine growth control), and estrogen and progesterone receptors (as endocrine parameters of estrogen responsiveness). In the tumor group with similar steroid receptor levels, low (0...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:

    authors: Nikolić-Vukosavljević D,Kanjer K,Branković-Magić M,Spuzić I

    更新日期:1994-01-01 00:00:00

  • MiR-34a-5p/PD-L1 axis regulates cisplatin chemoresistance of ovarian cancer cells.

    abstract::Ovarian cancer is the most lethal gynecologic malignancy in women with an increasing number of cases worldwide. Chemoresistance is the main obstacle for ovarian cancer treatment during clinical therapy. Previous studies found that programmed cell death 1 ligand 1 (PD-L1) was associated with chemoresistance of cancer. ...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:10.4149/neo_2019_190202N106

    authors: Zuo Y,Zheng W,Liu J,Tang Q,Wang SS,Yang XS

    更新日期:2020-01-01 00:00:00

  • Detection of p53 gene mutation by using a novel biosensor based on localized surface plasmon resonance.

    abstract::Few studies to date have reported on the development and application of a nanobiosensor based on localized surface plasmon resonance (LSPR) for detecting gene mutations. This study aimed to develop a novel LSPR biosensor used for detecting p53 mutation. Nanosphere lithography was used to fabricate the silver nanoparti...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:10.4149/neo_2012_045

    authors: Duan RQ,Yuan JL,Yang H,Luo XG,Xi MR

    更新日期:2012-01-01 00:00:00

  • Distribution and photodynamic effect of zinc phthalocyanine disulfonate in nude mice bearing mammary carcinoma.

    abstract::The distribution study of zinc phthalocyanine disulfonate (ZnPcS2) in nude mice bearing mammary carcinoma (T50/80) revealed a rapid uptake of the dye by tumor. In experimental photodynamic therapy (PDT), the tumors were exposed to laser radiation (670 nm, 100 mW/cm2, 150 J/ /cm2) after intravenous administration of Zn...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:

    authors: Mosa M,Zitko M,Poucková P

    更新日期:1997-01-01 00:00:00

  • Evaluation of p53 and bcl-2 oncoprotein expression in precancerous lesions of the oral cavity.

    abstract::The oral cavity is continually exposed to various traumas due to the effect of thermal, mechanical and chemical stimuli, which when accompanied by inflammatory states may promote the growth of neoplastic changes. Numerous studies have revealed a correlation between the expression of p53 and Bcl-2 proteins and the prog...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:

    authors: Sulkowska M,Famulski W,Chyczewski L,Sulkowski S

    更新日期:2001-01-01 00:00:00

  • Value of lymphangiography in the diagnosis and treatment of lymphangioma.

    abstract::On the basis of the author's own results and literary data emphasis is laid on the significance of lymphography for confirming or establishing a diagnosis, for determining the extent of a lesion and for proper considerations on indications for surgical treatment. Relymphography following a surgical intervention is cap...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:

    authors: Kutarna A

    更新日期:1975-01-01 00:00:00

  • Deletion mapping of chromosome 4q22-35 and identification of four frequently deleted regions in head and neck cancers.

    abstract::Head and neck squamous cell carcinoma (HNSCC) is a diverse group of cancers that are frequently aggressive in their biologic behavior. Inactivation of tumor suppressor gene (TSG) is one of the most critical steps leading to HNSCC. Loss of heterozygosity analysis is very sensitive method for the detection of frequent a...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:

    authors: Cetin E,Cengiz B,Gunduz E,Gunduz M,Nagatsuka H,Bekir-Beder L,Fukushima K,Pehlivan D,N MO,Nishizaki K,Shimizu K,Nagai N

    更新日期:2008-01-01 00:00:00

  • The levels of NAD and NADH in blood of patients with cancer.

    abstract::The levels of nicotinamide adenine dinucleotide (NAD) and NADH in blood of patients with cancer in various stages of development as well as their modification after glucose administration were determined in 188 respectively 77 cases. NAD was significantly decreased in patients with cervix and breast carcinoma but unal...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:

    authors: Comes R,Mustea I

    更新日期:1976-01-01 00:00:00

  • Case series on multiple prostate re-irradiation for locally recurrent prostate cancer: something ventured, something gained.

    abstract::The aim is to present the technical feasibility and efficacy of multiple re-irradiation (re-EBRT) for local recurrence of prostate cancer (PCa) using retrospective analysis of an updated series of patients who received ablative re-EBRT with stereotactic image-guided technique for isolated local recurrence of PCa. Eigh...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:10.4149/neo_2018_180723N520

    authors: Volpe S,Jereczek-Fossa BA,Zerini D,Rojas DP,Fodor C,Vavassori A,Romanelli P,Vigorito S,Rondi E,Comi S,Cambria R,Cattani F,Dicuonzo S,De Marco P,Beltramo G,Musi G,De Cobelli O,Marvaso G,Orecchia R

    更新日期:2019-03-05 00:00:00

  • Estimation of changes in vimentin filaments induced by etoposide and doxorubicin in human leukemia cell line K-562 by using immunofluorescence microscopy.

    abstract::This study was undertaken to examine the influence of etoposide and doxorubicin on the distribution of vimentin in cells of human leukemia cell line K-562 by using immunofluorescence microscopy. The cells were cultured with 5 different doses of etoposide: 0.02, 0.2, 2, 20, 200 microM/l and three doses of doxorubicin: ...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:

    authors: Grzanka A

    更新日期:2001-01-01 00:00:00

  • Serum and urinary levels of CD222 in cancer: origin and diagnostic value.

    abstract::The mannose 6-phosphate/insulin-like growth factor 2 receptor (CD222, M6P/IGF2R) is a multifunctional transmembrane type I receptor, mostly localized intracellularly, less on the surface of all types of mammalian cells. It is known both to transport lysosomal enzymes through their mannose 6-phosphate moieties and to i...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:10.4149/neo_2018_171203N792

    authors: Vicikova K,Petrovcikova E,Manka P,Drach J,Stockinger H,Leksa V

    更新日期:2018-09-19 00:00:00

  • miR-155-5p increases the sensitivity of liver cancer cells to adriamycin by regulating ATG5-mediated autophagy.

    abstract::Liver cancer is the sixth most prevalent cancer worldwide and the third leading cause of cancer-related deaths. Adriamycin (ADR) resistance, which often leads to the progression of malignant tumors, is a major treatment obstacle for liver cancer. It has been confirmed that miR-155-5p could reverse drug resistance in h...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:10.4149/neo_2020_200106N17

    authors: Yu Q,Xu XP,Yin XM,Peng XQ

    更新日期:2021-01-01 00:00:00

  • Expression of heat shock protein 70 (HSP70) in patients with colorectal adenocarcinoma--immunohistochemistry and Western blot analysis.

    abstract::The role of heat shock protein 70 (HSP70) expression has been investigated in various types of tumors. There are only little and controversial data about its clinical relevance in colorectal carcinoma, one of the most common carcinomas observed in humans. In this study we investigated expression of HSP70 in human colo...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:

    authors: Milićević ZT,Petković MZ,Drndarević NC,Pavlović MD,Todorović VN

    更新日期:2007-01-01 00:00:00

  • Microsomal epoxide hydrolase polymorphisms, cigarette smoking and prostate cancer risk in the Slovak population.

    abstract::Polymorphisms in tobacco carcinogen metabolizing enzymes may generate interindividual variations towards the risk of developing prostate cancer. One of these enzymes is microsomal epoxide hydrolase (EPHX1) which metabolizes polycyclic aromatic hydrocarbons, or PAH, carcinogens found in cigarette smoke. The activity of...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:10.4149/neo_2012_010

    authors: Sivonova MK,Dobrota D,Matakova T,Dusenka R,Grobarcikova S,Habala V,Salagovic J,Tajtakova M,Pidanicova A,Valansky L,Lachvacs L,Kliment J Jr,Nagy V,Kliment J

    更新日期:2012-01-01 00:00:00

  • Are stromal fibroblasts from cervical tumors suitable to predict normal tissue radiation reaction?

    abstract::We examined the effect of gamma-irradiation (4 Gy) alone or combined with estrogen (17beta-estradiol 15 microM) treatment on the radiation response of stromal fibroblasts from cervical tumors. The fibroblasts were derived from tumors of 9 younger (<50 years) and 9 older (>50 years) cervical cancer patients. A normal f...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:

    authors: Gasinska A,Adamczyk A,Kojs Z,Szumiel I

    更新日期:2004-01-01 00:00:00

  • Individual-level data on the relationships of progression-free survival, post-progression survival, and tumor response with overall survival in patients with advanced non-squamous non-small cell lung cancer.

    abstract::The effects of first-line chemotherapy on overall survival (OS) might be confounded by subsequent therapies in patients with non-small cell lung cancer (NSCLC). We examined whether progression-free survival (PFS), post-progression survival (PPS), or tumor response could be valid surrogate endpoints for OS after first-...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:10.4149/neo_2014_030

    authors: Imai H,Takahashi T,Mori K,Ono A,Akamatsu H,Shukuya T,Taira T,Kenmotsu H,Naito T,Murakami H,Endo M,Nakajima T,Yamamoto N

    更新日期:2014-01-01 00:00:00

  • Mitochondrial ATPase of Zajdela hepatoma. V. Mitochondria of Zajdela hepatoma contain membrane sectors of ATPase complex unassociated with F1.

    abstract::Relative content of membrane sectors of ATPase complex in rat liver and Zajdela hepatoma mitochondria and the ability of mitochondrial membrane of the two sources to bind isolated soluble (F1) ATPase were examined. Approximately equal concentrations of oligomycin were required for 50% inhibition of ATPase activity in ...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:

    authors: Kuzela S,Kolarov J,Krempaský V,Luciaková K,Ujházy V

    更新日期:1978-01-01 00:00:00

  • The influence of patients age, type of tumor growth, hematocrit, and radiation-induced tumor regression on the prognosis of advanced uterine cervix carcinoma.

    abstract::The age of patients, type of tumor growth, pretreatment hematocrit, and radiation-induced tumor regression were evaluated as possible prognostic factors in 222 patients with advanced cervical cancer treated at the Institute of Clinical Oncology in Bratislava in the period from 1960 through 1980. The five-year disease-...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:

    authors: Boljesíková E,Gyárfásová M,Durkovský J

    更新日期:1988-01-01 00:00:00

  • Quadruple cancer, including triple cancers in the head and neck region.

    abstract::Multiple primary tumors are not rare: they are encountered in 3-5% of malignant tumors. They are particularly frequent in the head and neck [20]. They are most often met with secondary malignant tumors; triple tumors occur in only 0.5%, quadruple tumors in 0.3% of malignant tumors. The possibility of developing a seco...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:

    authors: Németh Z,Czigner J,Iván L,Ujpál M,Barabás J,Szabó G

    更新日期:2002-01-01 00:00:00

  • Radiosensitizer AK-2123 as modulating agent in the chemotherapy of experimental metastases.

    abstract::Therapeutic effect of Cyclophosphamide (CPA) and radiosensitizer AK-2123 (AK) combination versus CPA alone in the same doses was investigated on transplanted LL carcinoma and B 16 melanoma. Antimetastatic efficacy of different doses of CPA and combined therapy was evaluated. Our data demonstrate that the effect of com...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:

    authors: Konovalova NP,Diatchkovskaya RF,Volkova LM,Kagiya TV

    更新日期:1995-01-01 00:00:00

  • Expression of cyclin A in human leukemia cell lines HL-60 and K-562 at the level of light and electron microscope by using immunocytochemical methods.

    abstract::In this study subcellular localization of cyclin A in the human promyelocytic leukemia cell line HL-60 and the human erythroleukemic K-562 cell line was examined by immunocytochemical methods. Studies were based on light and electron microscope evaluations. Cyclin A at the level of light microscope was present in 48% ...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:

    authors: Grzanka A,Styczynski J

    更新日期:2001-01-01 00:00:00

  • Breast and other cancer deaths in a mental hospital.

    abstract::The neuroleptics, well known as stimulants of prolactin release, are supposed to increase breast cancer incidence. To verify this hypothesis, we selected a group of 853 deaths of female inpatients with mental diseases recorded in the Dr. G. Marinescu Hospital between 1929 and 1978. Using proportionally and indirect st...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:

    authors: Costa D,Mesteş E,Coban A

    更新日期:1981-01-01 00:00:00

  • Vitamin D receptor FokI, BsmI, ApaI, and TaqI polymorphisms and the susceptibility to breast cancer: a meta-analysis.

    abstract::The goal of this study is to examine whether vitamin D receptor (VDR) polymorphisms are associated with the susceptibility to breast cancer. Meta-analysis was employed to investigate the association between the VDR FokI, BsmI, ApaI, and TaqI polymorphisms and the incidence of breast cancer.A total of 32 comparative st...

    journal_title:Neoplasma

    pub_type: 杂志文章,meta分析

    doi:10.4149/neo_2014_077

    authors: Lee YH,Song GG

    更新日期:2014-01-01 00:00:00

  • Suppressing the secretion of exosomal miR-19b by gw4869 could regulate oxaliplatin sensitivity in colorectal cancer.

    abstract::Oxaliplatin is commonly used in managing malignancy, including colorectal cancer. While treatment often fails due to decreased drug sensitivity, the mechanisms involved are not clear. In this study, we investigate how exosomal miR-19b participates in oxaliplatin sensitivity and then prove that miR-19b down-regulates o...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:10.4149/neo_2018_180306N155

    authors: Gu YY,Yu J,Zhang JF,Wang C

    更新日期:2019-01-15 00:00:00

  • Activation of HLA-G expression by 5-aza-2 - deoxycytidine in malignant hematopoetic cells isolated from leukemia patients.

    abstract::Human leukocyte antigen - G (HLA-G) is a non-classical HLA class I antigen with restricted distribution in normal tissues. Ectopic HLA-G expression observed at some pathological circumstances as malignant transformation might be triggered by epigenetic modifications such as DNA demethylation. Recently it was demonstra...

    journal_title:Neoplasma

    pub_type: 杂志文章

    doi:10.4149/neo_2009_06_514

    authors: Polakova K,Bandzuchova E,Sabty FA,Mistrik M,Demitrovicova L,Russ G

    更新日期:2009-01-01 00:00:00