Abstract:
:In 1961 the WHO Expert Committee on Biological Standardization asked the National Institute for Medical Research, London, to collect and study material to replace the first International Standard for Serum Gonadotrophin, stocks of which were running low. This paper describes the material that was contributed, its distribution into ampoules and the international collaborative assay to compare its biological activity with that of the first International Standard. On the basis of the results obtained the material has been established as the second International Standard for Serum Gonadotrophin, with a potency of 1600 International Units per ampoule. The International Unit for Serum Gonadotrophin is thus defined as the activity contained in 0.003569 mg of the second International Standard for Serum Gonadotrophin.
journal_name
Bull World Health Organjournal_title
Bulletin of the World Health Organizationauthors
Bangham DR,Woodward PMsubject
Has Abstractpub_date
1966-01-01 00:00:00pages
761-73issue
5eissn
0042-9686issn
1564-0604journal_volume
35pub_type
杂志文章abstract::Some of the acute diarrhoeas of man are specific infectious diseases. Another and major proportion have no demonstrated infectious agent. No characteristic clinical pattern regularly distinguishes one specific disease entity from another, nor specific from non-specific infections, nor epidemic from endemic disease. Si...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1964-01-01 00:00:00
abstract::Hepatic damage caused by chronic exposure to arsenic has been frequently described. Here we report on 13 patients from West Bengal, India, who consumed large amounts of arsenic in drinking water. An epidemiological investigation of the study area showed evidence of chronic arsenical dermatosis and hepatomegaly in 62 (...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract:OBJECTIVE:To examine infant feeding intentions of HIV-infected and uninfected women and the appropriateness of their choices according to their home resources; and to determine their adherence to their intentions in the first postnatal week. METHODS:Feeding intentions of pregnant women were compared against four resou...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/blt.06.032441
更新日期:2007-04-01 00:00:00
abstract::In Iran, microscopic examination of skin scrapings from 2202 individuals with clinically diagnosed cutaneous leishmaniasis (CL) lesions revealed the presence of amastigotes in 1123 cases (51.0%). Bacteriological examinations of the lesions indicated that 788 individuals (35.7%) were also infected with one or more path...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::The magnitude and duration of dengue viraemia were studied in 153 patients with naturally acquired dengue infection in Jakarta, Indonesia. The duration of viraemia ranged from 2 to 12 days, but most patients had detectable circulating virus for 4-5 days. Accurate measurement of peak virus titres was not possible for m...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
abstract::The magnitude of the malaria problem in tropical Africa has been a deterrent to a large-scale control effort as long as the aim was conceived to be only a reduction in transmission. The focus on local priorities brought about by the primary health care approach has resulted in the formulation of a strategy of malaria ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::With an increasing number of malaria eradication programmes approaching or entering the consolidation phase, the epidemiological features of disappearing malaria are getting better known and defined. At the same time, the old classical methods of measuring malaria prevalence have become inadequate and new methods for ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1960-01-01 00:00:00
abstract::Agglutinating antibodies produced in an adult rabbit in response to intravenous injections of live Leptospira sp. (serotype biflexa, strain Waz), consisted of a 19S component (present at day 6 after inoculation) and a 7S component (present at day 6 after inoculation). Both 19S and 7S antibodies persisted in the serum ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1970-01-01 00:00:00
abstract::Reported is the assessment of a model to evaluate the efficacy of public health programmes, using the example of the Chagas Disease Control Programme in the State of Minas Gerais, Brazil. The reduction in Trypanosoma cruzi infection rates in areas where interventions had been carried out for 5 years and 10 years, resp...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract::Surveillance-containment units were established in 1969 in four States of Brazil as part of the national smallpox eradication programme. Their responsibilities included both the investigation of reported cases and the control of outbreaks, and the further extension and development of the reporting network. Altogether,...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1972-01-01 00:00:00
abstract:OBJECTIVE:To estimate post-traumatic stress disorder (PTSD) symptoms in those injured and not injured by landmines or unexploded ordnance (UXO) in rural Lao People's Democratic Republic and to determine whether the perception of social support was associated with PTSD symptom severity. METHODS:A community survey was c...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.12.115311
更新日期:2013-10-01 00:00:00
abstract::The insecticidal activity of synthetic pyrethroids was compared with that of the natural pyrethrins, which have been used on a world-wide scale as active ingredients for insecticidal aerosols or mosquito coils.All of the synthetic pyrethroids were found to be more stable than the pyrethrins. Tetramethrin showed a very...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1971-01-01 00:00:00
abstract::Investigators using questionnaires are usually confronted with an enormous number of different responses whose significance with respect to a particular characteristic is not immediately clear. This paper presents a simple computational technique for determining the relative merits of each question and a score for eac...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1972-01-01 00:00:00
abstract::The authors have compared the value of multiple doses of duck-embryo and HEP Flury vaccine with that of pooled 5% sheep-brain vaccine in experimental rabies infection in guinea-pigs. They found that the duck-embryo vaccine given in a dosage corresponding to 14 ml of 10% vaccine (the dosage recommended for human treatm...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1963-01-01 00:00:00
abstract:OBJECTIVE:To compare sentinel and population-based surveillance of the effect of seven-valent pneumococcal conjugate vaccine (PCV7), introduced in 2000, on the hospitalization of children aged under 5 years with invasive pneumococcal disease (IPD) in the United States of America. METHODS:Population surveillance data w...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.11.098178
更新日期:2012-08-01 00:00:00
abstract::This report from the Tuberculosis Chemotherapy Centre, Madras, summarizes the progress over a 5-year period of 193 patients with newly diagnosed, sputum-positive pulmonary tuberculosis who were admitted to a concurrent comparison of home and sanatorium treatment for one year with isoniazid plus PAS. Previous reports h...
journal_title:Bulletin of the World Health Organization
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1966-01-01 00:00:00
abstract::Tuberculosis (TB) is a major public health problem in eastern Europe. Since 1990, the incidence rates of TB have continued to increase in Belarus, the Russian Federation, the Ukraine and the central Asian republics of Kazakhstan, Kyrgyzstan, Tajikistan and Uzbekistan. Eastern Europe, and in particular the Russian Fede...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章,评审
doi:10.2471/blt.06.034991
更新日期:2008-02-01 00:00:00
abstract::The author reviews the growing body of evidence that urban populations of Culex pipiens fatigans have increased extensively during recent years in both Africa and Asia. Two main factors seem to be responsible-the spread of urbanization, providing favourable habitats for this essentially urban mosquito; and the increas...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1962-01-01 00:00:00
abstract::Studies on the prevalence and other epidemiological features of rheumatic fever and rheumatic heart disease and pilot prophylactic programmes have been carried out in India for the past 12 years or more. The results of these, together with data from other developing countries, have been taken into account in discussin...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1978-01-01 00:00:00
abstract::An outline is presented of progress in the development of health expectancy indicators, which are growing in importance as a means of assessing the health status of populations and determining public health priorities. ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract:PROBLEM:Propanil is an aniline herbicide that is widely used for rice cultivation, but is also used for self-poisoning. Toxicity from propanil is largely due to methemoglobinemia. In resource-poor settings, the capacity to determine methemoglobin concentration is insufficient and prevents effective case management, whi...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.15.158147
更新日期:2016-08-01 00:00:00
abstract::An epidemic of sleeping sickness, which started in 1976 in a focus within the county of Luuka in Central Busoga, has spread to cover the three districts of Busoga and large parts of the neighbouring districts of Tororo and Mukono. Forty-three isolates of the subgenus Trypanozoon from Busoga and Tororo (27 from man, 9 ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract:OBJECTIVE:To appraise the process of development and clinical content of national human immunodeficiency virus (HIV) clinical practice guidelines of countries in the eastern Mediterranean and to formulate recommendations for future guideline development and adaptation. METHODS:Twenty-three countries in the World Healt...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.10.083790
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVE:To assess the socioeconomic, geographical and demographic inequities in the use of postnatal health-care services in low- and middle-income countries. METHODS:We searched Medline, Embase and Cochrane Central databases and grey literature for experimental, quasi-experimental and observational studies that had...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章,meta分析,评审
doi:10.2471/BLT.14.140996
更新日期:2015-04-01 00:00:00
abstract:PROBLEM:In 2010, dengue virus (DENV) serotype-4 was detected during a dengue outbreak in the Amazonian city of Boa Vista. At that time Brazil was already endemic for DENV-1, DENV-2 and DENV-3. This was the first time DENV-4 was observed in the country after it was initially detected and eliminated in 1981. APPROACH:To...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.13.119081
更新日期:2014-09-01 00:00:00
abstract:OBJECTIVE:To determine the prevalence and intensity of Schistosoma japonicum infection and associated morbidity, and to estimate the infected human and buffalo populations in the Dongting Lake region, Hunan province, China. METHODS:We used data from the third national schistosomiasis periodic epidemiological survey (P...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/blt.06.034033
更新日期:2007-07-01 00:00:00
abstract::This literature review indicates that menstrual regulation during the fifth to seventh week of pregnancy is not always as free from risk as has sometimes been claimed. In particular, it has a higher failure rate, in terms of continued pregnancy, than has abortion by suction in later stages of pregnancy.Vacuum aspirati...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1979-01-01 00:00:00
abstract::The respective vectors of the two forms of bilharziasis in Egypt do not have the same ecological distribution. Bulinus truncatus is most abundant in large canals, and decreases in density as the water approaches and flows into drains. Biomphalaria alexandrina is most abundant in drains, and decreases in density upstre...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1966-01-01 00:00:00
abstract::The international unit of colistin methane sulfonate has been defined by collaborative assay as the activity contained in 0.00007874 mg of the international reference preparation. The definition was based on results from 7 laboratories in 5 countries which carried out assays against their existing national standards. ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1973-01-01 00:00:00
abstract::Among 1109 patients with bacteriologically confirmed El Tor cholera admitted to the San Lazaro Hospital, Manila, in 1969, 11 patients continued to excrete vibrios of the same biotype and serotype in stools for more than 1 week in spite of antibiotic treatment.The strains isolated from these patients all belonged to th...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1970-01-01 00:00:00