Abstract:
:Between April and July 1966 a comparative trial of two live attenuated measles vaccines (Schwarz and Beckenham 31), given intramuscularly or intradermally, was conducted in Hong Kong. Some 910 non-immune children completed the trial. The Beckenham 31 vaccine caused significantly more complications than Schwarz vaccine, but it also resulted in a much higher mean antibody titre by both intramuscular and intradermal injection than did Schwarz vaccine. The seroconversion rates were satisfactory for both vaccines given intramuscularly but not for either given intradermally (at one-fifth the recognized intramuscular dose).The authors suggest that either vaccine may usefully be given for measles prophylaxis. The choice between Beckenham 31, with a higher complication rate and higher antibody levels, and Schwarz, with fewer complications but lower antibody levels, would depend on the type of community, the adequacy of the medical services, the severity of measles and an assessment of how either vaccine, with its known complications, might affect other immunization programmes.
journal_name
Bull World Health Organjournal_title
Bulletin of the World Health Organizationauthors
subject
Has Abstractpub_date
1967-01-01 00:00:00pages
375-84issue
3eissn
0042-9686issn
1564-0604journal_volume
36pub_type
杂志文章abstract::A 7-valent pneumococcal polysaccharide-protein conjugate vaccine (PCV7) was licensed in the United States of America in 2000, but no comprehensive postmarketing review of safety has been carried out. We conducted a systematic review of the safety of PCV7 and other pneumococcal conjugate vaccines. A total of 42 studies...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章,评审
doi:10.2471/blt.07.048025
更新日期:2008-05-01 00:00:00
abstract::This paper describes the organization of an epidemiological survey, carried out by the Lipid Centre of the Institute of Experimental Medicine in Leningrad, particularly the ways in which subjects were recruited. The different methods of recruitment resulted in a total population response of 78.14%. A time index is int...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
abstract::A strain of Aëdes aegypti was recently found in Puerto Rico which proved to be resistant to both DDT and dieldrin. This paper reports on genetical studies of this strain to determine whether a single entity is involved or two distinct resistances. Tests carried out by repeated back-crossing combined with selection pre...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1961-01-01 00:00:00
abstract::The deposit or precipitate formed after storage at -20 degrees C of allantoic fluids infected with influenza virus contains a considerable amount of the virus. It has been found that by treatment of this material, after thawing, with sodium chloride and subsequent purification of the treated fluid, all the virus origi...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1961-01-01 00:00:00
abstract::The prevalence of ringworm of the scalp in many countries, and the fact that many of the current measures to control it are inconvenient for mass use, lend particular interest to the account given in this paper of mass treatment of tinea capitis in an Arab village in Israel. A total of 446 cases were treated, on an am...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1960-01-01 00:00:00
abstract::In serological tests for syphilis, leprosy sera often give biologically false positive reactions. These may be due to the presence of non-specific elements-for example, the ubiquitous lipid antibodies-in the leprosy sera; or they may be the result of errors in technique or unfavourable working conditions in the labora...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1960-01-01 00:00:00
abstract::The public sector in developing countries is increasingly contracting with the non-state sector to improve access, efficiency and quality of health services. We conducted a multicountry study to assess the range of health services contracted out, the process of contracting and its influencing factors in ten countries ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/blt.06.033027
更新日期:2006-11-01 00:00:00
abstract::Twenty-six patients suffering from methylmercury poisoning were treated by different therapeutic regimes. Seven received penicillamine or N-acetyl-d-L-penicillamine, 10 were treated with dimercaprol sulfonate and 9, who could not be treated, were given a placebo and were used as controls. Penicillamine, N-acetyl-d-L-p...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00
abstract::The paucity of information on the ecology of wild animal reservoirs over most of the world is one of the factors that has led to hesitation and failure in controlling these diseases in many areas. Extensive application of ecological studies and methods would not only assist in zoonosis control but might well also lead...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1959-01-01 00:00:00
abstract::This paper generates and analyses survey data on inequalities in mortality among infants and children aged under five years by consumption in Brazil, Côte d'Ivoire, Ghana, Nepal, Nicaragua, Pakistan, the Philippines, South Africa, and Viet Nam. The data were obtained from the Living Standards Measurement Study and the...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章,评审
doi:
更新日期:2000-01-01 00:00:00
abstract::Investigations of experimental schistosomiasis haematobia have suffered for want of satisfactory mammals in which schistosome infections would establish host-parasite situations more or less comparable with those seen in man. As a consequence, mammals representing different major groups have been exposed to infection ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1971-01-01 00:00:00
abstract::The mechanisms of dissemination of arthropod-borne human and animal pathogens are of considerable interest to the epidemiologist, veterinarian and biologist. Birds which are hosts to such pathogens and their arthropod vectors could transport them over long distances during their spring and autumn migratory flights.In ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1964-01-01 00:00:00
abstract::This chapter presents the findings arrived at by applying the resource allocation model to tuberculosis control in the Republic of Korea. Optimum subprogrammes are obtained for the four objectives of the programme: reduction of disability, impairment, excess mortality, and economic loss. These subprogrammes are discus...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1973-01-01 00:00:00
abstract::In order to determine the effectiveness of anti-typhoid vaccines in man a controlled field trial, the first of its kind, was organized in 1954-60 in the town and district of Osijek, Yugoslavia. Heat-killed, phenol-preserved and alcohol-killed, alcohol-preserved anti-typhoid monovaccines were used, with phenolized dyse...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1962-01-01 00:00:00
abstract::The author reviews the published findings on the carriage of Staphylococcus pyogenes var. aureus during the last two decades, dealing mainly with observations made in British Commonwealth countries, Scandinavia and the USA. The importance of the role played by staphylococcal carriers in the spread of infection both in...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1961-01-01 00:00:00
abstract::Recent research carried out on kwashiorkor in Kampala, Uganda, is discussed. The first essential in both the treatment and the prevention of this disease being a diet rich in protein (preferably animal protein, to ensure an adequate intake of vitamin B(12) and a satisfactory mixture of amino-acids), methods of incorpo...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1953-01-01 00:00:00
abstract::Presented is an assessment of the cost-effectiveness of cataract surgery using cost and services data from the Lumbini Zonal Eye Care Programme in Nepal. The analysis suggests that cataract surgery may be even more cost-effective than previously reported. Under a "best estimate" scenario, cataract surgery had a cost o...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::Water velocity is an important physical factor in the conditioning of streams and canals as habitats for the intermediate snail host of bilharziasis. Ecologists in most of the bilharziasis endemic areas have studied the resistance of these molluscs to the disturbing action of water motion. However, the complex nature ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1962-01-01 00:00:00
abstract::As culture filtrates of Mycobacterium tuberculosis have been shown by numerous workers to be antigenically heterogeneous, a series of experiments has been started to identify some of the different antigens likely to be useful in laboratory tests for measuring the antibodies in human blood. The work involves the fracti...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1955-01-01 00:00:00
abstract::This report from the Tuberculosis Chemotherapy Centre, Madras, summarizes the progress over a 5-year period of 193 patients with newly diagnosed, sputum-positive pulmonary tuberculosis who were admitted to a concurrent comparison of home and sanatorium treatment for one year with isoniazid plus PAS. Previous reports h...
journal_title:Bulletin of the World Health Organization
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1966-01-01 00:00:00
abstract::Health technology assessment (HTA) is the multidisciplinary study of the implications of the development, diffusion and use of health technologies. It supports health-policy decisions by providing a joint knowledge base for decision-makers. To increase its policy relevance, HTA tries to extend beyond effectiveness and...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/blt.08.051078
更新日期:2008-08-01 00:00:00
abstract:OBJECTIVE:To derive regional weight-for-age growth references to help optimize age-based dosing of antimalarials in Africa, the Americas, South-East Asia and the Western Pacific. METHODS:A weight-for-age database was constructed from pre-existing population-based anthropometric data obtained from household surveys and...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.14.139113
更新日期:2015-02-01 00:00:00
abstract::The operational and diagnostic performance of a two-step method for the cost-effective screening of urinary schistosomiasis was investigated in the Kilosa District of east-central Tanzania. In the first step a simple questionnaire was administered to 15,073 primary schoolchildren by their class teachers over a 4-week ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVE:To assess the effectiveness of decentralized treatment and care for patients with multidrug-resistant (MDR) tuberculosis, in comparison with centralized approaches. METHODS:We searched ClinicalTrials.gov, the Cochrane library, Embase®, Google Scholar, LILACS, PubMed®, Web of Science and the World Health Orga...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章,meta分析,评审
doi:10.2471/BLT.17.193375
更新日期:2017-08-01 00:00:00
abstract::Although trench fever appears to be endemic in many areas of the world, recognition of the disease has been handicapped by the difficulties of making a clinical diagnosis and the unavailability of a simple laboratory procedure to establish the etiology. The author describes a method for the in vitro cultivation of Ric...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1966-01-01 00:00:00
abstract::The QBC (quantitative buffy coat) technique was compared with that of the Giemsa-stained thick blood film (GTF) under field conditions in Junlian and Mingshan counties, Sichuan, China, for rapid diagnosis of vivax malaria. Blood samples were collected from 364 volunteer villagers, and each sample was examined with bot...
journal_title:Bulletin of the World Health Organization
pub_type: 临床试验,杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::Airport and aviation authorities are starting to recognize that airports do not have to be unhealthy. Sima Barmania reports. ...
journal_title:Bulletin of the World Health Organization
pub_type: 新闻
doi:10.2471/BLT.18.020818
更新日期:2018-08-01 00:00:00
abstract::The total cost of the Expanded Programme on Immunization and of its various components in the Gambia over a period of one year (from July 1980 to June 1981) was investigated, and the costs per immunization dose and per fully immunized child were calculated. The total costs were to a large extent (45%) due to the cost ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::The effects of flea control on the prevalence of (Pasteurella) pestis antibody rates in the California vole, Microtus californicus, were studied in San Mateo County, California, USA. In this area, which had shown antibody prevalence rates of 50% or more during epizootics in previous years, continuous flea control meas...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1971-01-01 00:00:00
abstract::The acute toxicity of most of the commonly used organophosphorus insecticides is essentially the same. A few compounds with low toxicity, such as malathion, have been developed but further efforts in that direction are needed. Most of the organophosphorus insecticides exert a generalized cholinergic action by inhibiti...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1971-01-01 00:00:00