Retraction of the lower eyelid.

abstract：:We compared the effect of metrizamide and its parent compound glucosamine on the kinetics of dog brain hexokinase. The Michaelis constant (Km) for glucose rose from 0.065 to 0.15 to 0.28 mM in the presence of 0, 16, and 32 mM metrizamide, respectively. For 0, 1.5, and 3.7 mM glucosamine, the Km values were 0.065, 0.4,...

journal_title：Neurology

authors： Bertoni JM,Steinman CG

更新日期：1982-03-01 00:00:00

abstract：:Parent of origin effects caused by genomic imprinting may influence the phenotypic expression of a number of heritable human disorders. To test this phenomenon in Tourette's syndrome (TS), we studied 437 first degree relatives systematically ascertained through 57 probands. We compared age at onset, age at diagnosis, ...

journal_title：Neurology

authors： Eapen V,O'Neill J,Gurling HM,Robertson MM

更新日期：1997-04-01 00:00:00

abstract：OBJECTIVE:Asians who carry the HLA-B*1502 allele have an elevated risk of developing Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) when treated with the antiepileptic drugs (AEDs) carbamazepine (CBZ) and phenytoin (PHT). With a focus on Singapore, this analysis identifies circumstances in which ge...

journal_title：Neurology

authors： Dong D,Sung C,Finkelstein EA

更新日期：2012-09-18 00:00:00

abstract：OBJECTIVE:To construct a grading score that predicts neurologic function 1 year after diagnosis of anti-NMDA receptor (NMDAR) encephalitis. METHODS:Three hundred eighty-two patients with detailed information and functional status at 1 year were studied. Factors associated with poor status (defined as modified Rankin S...

journal_title：Neurology

authors： Balu R,McCracken L,Lancaster E,Graus F,Dalmau J,Titulaer MJ

更新日期：2019-01-15 00:00:00

abstract：OBJECTIVE:To develop evidence-based recommendations for complementary and alternative medicine (CAM) in multiple sclerosis (MS). METHODS:We searched the literature (1970-March 2011; March 2011-September 2013 MEDLINE search), classified articles, and linked recommendations to evidence. RESULTS AND RECOMMENDATIONS:Clin...

journal_title：Neurology

authors： Yadav V,Bever C Jr,Bowen J,Bowling A,Weinstock-Guttman B,Cameron M,Bourdette D,Gronseth GS,Narayanaswami P

更新日期：2014-03-25 00:00:00

abstract：OBJECTIVE:To measure changes in psychometric state, neural activation, brain volume (BV), and cerebral metabolite concentrations during treatment of minimal hepatic encephalopathy. METHODS:As proof of principle, 22 patients with well-compensated, biopsy-proven cirrhosis of differing etiology and previous minimal hepat...

journal_title：Neurology

authors： McPhail MJ,Leech R,Grover VP,Fitzpatrick JA,Dhanjal NS,Crossey MM,Pflugrad H,Saxby BK,Wesnes K,Dresner MA,Waldman AD,Thomas HC,Taylor-Robinson SD

更新日期：2013-03-12 00:00:00

abstract：BACKGROUND:Pregnancy registries for women taking anticonvulsant drugs have been developed to determine more efficiently the fetal risks of each drug. A total of 722 drug-exposed pregnancies are needed to identify a sevenfold increase in the rate of occurrence of a specific abnormality, such as spina bifida, with a freq...

journal_title：Neurology

authors： Holmes LB,Baldwin EJ,Smith CR,Habecker E,Glassman L,Wong SL,Wyszynski DF

更新日期：2008-05-27 00:00:00

abstract：:In this study, we examined the topographic involvement of the putaminal projection neurons and their axons in the globus pallidus and substantia nigra, which we visualized by calcineurin immunostaining, in the basal ganglia of patients with striatonigral degeneration (SND). In all cases examined, there was a marked de...

journal_title：Neurology

authors： Goto S,Matsumoto S,Ushio Y,Hirano A

更新日期：1996-10-01 00:00:00

abstract：:The apolipoprotein E gene has been associated with various types of dementia. We studied the connection between the APOE gene and the risk and onset of disease in 34 patients with clinically diagnosed frontal lobe dementia (FLD) derived from a population-based study in the Netherlands. A significant increased risk of ...

journal_title：Neurology

authors： Stevens M,van Duijn CM,de Knijff P,van Broeckhoven C,Heutink P,Oostra BA,Niermeijer MF,van Swieten JC

更新日期：1997-06-01 00:00:00

abstract：OBJECTIVES:To identify gene mutations in patients with dystroglycanopathy and prove pathogenicity of those mutations using an in vitro cell assay. METHODS:We performed whole-exome sequencing on 20 patients, who were previously diagnosed with dystroglycanopathy by immunohistochemistry and/or Western blot analysis. We a...

journal_title：Neurology

authors： Dong M,Noguchi S,Endo Y,Hayashi YK,Yoshida S,Nonaka I,Nishino I

更新日期：2015-01-20 00:00:00

abstract：BACKGROUND:Multiple sclerosis (MS) is a neurodegenerative disease associated with marked impairments in health-related quality of life (HRQoL). Although standard clinical end points such as the Expanded Disability Status Scale and annualized relapse rate remain useful in assessing MS activity and severity, these measur...

journal_title：Neurology

authors： Miller D,Rudick RA,Hutchinson M

更新日期：2010-04-27 00:00:00

abstract：:Immitation synkinesia is usually associated with thalamic or parietal lesions. Analysis of three cases shows that the lesions may affect the posterior columns of the spinal cord or even the peripheral nervous system. In our cases, two facts stand out, a large measure of integrity of motor activity and predominant dist...

journal_title：Neurology

authors： Cambier J,Dehen H

更新日期：1977-07-01 00:00:00

abstract：:We established the frequency of Horner's syndrome (HS) in 248 elective patients after coronary artery bypass surgery. Patients were evaluated neurologically pre- and post-operatively and 6 months after surgery. Nineteen patients (7.7%) developed unilateral HS postoperatively, 12 involving the left eye. The finding per...

journal_title：Neurology

authors： Barbut D,Gold JP,Heinemann MH,Hinton RB,Trifiletti RR

更新日期：1996-01-01 00:00:00

abstract：:The P3 component of the auditory evoked potential has been shown to reflect "endogenous" processes related to cognition. This component was measured serially in seven patients who had confusional states or dementing illnesses that fluctuated in severity over time. The latency of P3 component reflected the clinical imp...

journal_title：Neurology

authors： Goodin DS,Starr A,Chippendale T,Squires KC

更新日期：1983-09-01 00:00:00

abstract：:The progressive myoclonus epilepsies (PMEs) are a devastating group of rare disorders(1) that manifest with increasing action myoclonus, which is also present at rest but activates with stimuli such as noise, light, or touch. Ultimately, patients become wheelchair-bound and experience early death. Neurologic signs tha...

journal_title：Neurology

authors： Knupp K,Wirrell E

更新日期：2014-02-04 00:00:00

abstract：OBJECTIVE:To explore sensitivity of optical coherence tomography (OCT) in detecting prior unilateral optic neuritis. METHODS:This is a retrospective, observational clinical study of all patients who presented from January 1, 2014, to January 6, 2017, with unilateral optic neuritis and OCT available at least 3 months a...

journal_title：Neurology

authors： Xu SC,Kardon RH,Leavitt JA,Flanagan EP,Pittock SJ,Chen JJ

更新日期：2019-02-05 00:00:00

abstract：BACKGROUND:After 1 to 4 years, seizure-free children with epilepsy are encouraged to stop daily antiepileptic drug (AED) treatment. Approximately 70% are successful. The authors examined how often intractable epilepsy follows discontinuation of AED treatment in a population-based cohort of children with epilepsy. METH...

journal_title：Neurology

authors： Camfield P,Camfield C

更新日期：2005-03-22 00:00:00

abstract：OBJECTIVES:Assuming the involvement of homocysteine in a generalized small-vessel disease, we investigated the association of homocysteine levels with progression of white matter lesions, lacunar infarcts, and kidney disease. METHODS:Within the SMART-MR (Second Manifestations of ARTerial disease-Magnetic Resonance) St...

journal_title：Neurology

authors： Kloppenborg RP,Geerlings MI,Visseren FL,Mali WP,Vermeulen M,van der Graaf Y,Nederkoorn PJ,SMART Study Group.

更新日期：2014-03-04 00:00:00

abstract：:We measured oxygen consumption in the exercising lower limb by using noninvasive tissue oximetry with the near-infrared spectra of hemoglobin in the quadriceps muscle during bicycle ergometer exercise in four normal controls and three patients with chronic progressive external ophthalmoplegia (CPEO) as well as one pat...

journal_title：Neurology

authors： Abe K,Matsuo Y,Kadekawa J,Inoue S,Yanagihara T

更新日期：1997-09-01 00:00:00

abstract：:T, B, and "null" lymphocytes were determined in peripheral blood obtained from 24 control subjects and 15 multiple sclerosis patients. The total number of lymphocytes and T lymphocytes were reduced significantly in multiple sclerosis patients as compared with those of controls. Although the percentage of B lymphocytes...

journal_title：Neurology

authors： Reddy MM,Goh KO

更新日期：1976-10-01 00:00:00

abstract：:We studied the effects of low-frequency transcranial magnetic stimulation (TMS) on motor cortex excitability in humans. TMS at 0.1 Hz for 1 hour did not change cortical excitability. Stimulation at 0.9 Hz for 15 minutes (810 pulses), similar to the parameters used to induce long-term depression (LTD) in cortical slice...

journal_title：Neurology

authors： Chen R,Classen J,Gerloff C,Celnik P,Wassermann EM,Hallett M,Cohen LG

更新日期：1997-05-01 00:00:00

abstract：OBJECTIVE:To examine the relation of nonsteroidal anti-inflammatory drugs (NSAIDs) to incident Alzheimer disease (AD), change in cognition, and AD pathology. METHODS:Participants were 1,019 older Catholic clergy followed up annually for up to 12 years (mean baseline age = 75.0 years, education = 18.1 years, Mini-Menta...

journal_title：Neurology

authors： Arvanitakis Z,Grodstein F,Bienias JL,Schneider JA,Wilson RS,Kelly JF,Evans DA,Bennett DA

更新日期：2008-06-03 00:00:00

abstract：OBJECTIVE:To evaluate the usefulness of a mismatch between the severity of acute clinical manifestations and the diffusion-weighted imaging (DWI) lesion in predicting early stroke outcome and infarct volume. METHODS:One hundred sixty-six patients with a hemispheric ischemic stroke of <12 hours' duration were studied. ...

journal_title：Neurology

authors： Dávalos A,Blanco M,Pedraza S,Leira R,Castellanos M,Pumar JM,Silva Y,Serena J,Castillo J

更新日期：2004-06-22 00:00:00

abstract：BACKGROUND:Progressive brain atrophy in multiple sclerosis (MS) may reflect neuroaxonal and myelin loss and MRI measures of brain tissue loss are used as outcome measures in MS treatment trials. This study investigated sample sizes required to demonstrate reduction of brain atrophy using three outcome measures in a par...

journal_title：Neurology

authors： Altmann DR,Jasperse B,Barkhof F,Beckmann K,Filippi M,Kappos LD,Molyneux P,Polman CH,Pozzilli C,Thompson AJ,Wagner K,Yousry TA,Miller DH

更新日期：2009-02-17 00:00:00

abstract：:Three patients presented with unilateral progressive optic neuropathy. None of these patients had signs of symptoms referable to the chiasm or eye, thus confining their decline in vision to the optic nerve. Clinical and neuroradiographic evidence suggested a meningioma involving the optic nerve at the orbital-canalicu...

journal_title：Neurology

authors： Gudeman SK,Selhorst JB,Susac JO,Waybright EA

更新日期：1982-06-01 00:00:00

abstract：:Patients with mild cognitive impairment (MCI) were assessed, and a metabolic profile associated with conversion to AD at 18-month follow-up was sought. As compared with nonconverters (n = 10), converters (n = 7) had lower fluorodeoxyglucose uptake in the right temporoparietal cortex (p = 0.02, corrected for cluster si...

journal_title：Neurology

authors： Chételat G,Desgranges B,de la Sayette V,Viader F,Eustache F,Baron JC

更新日期：2003-04-22 00:00:00

abstract：OBJECTIVE:To determine the prognosis of asymptomatic carotid artery occlusion. BACKGROUND:As opposed to symptomatic carotid occlusion, little information is available on the prognosis of asymptomatic carotid occlusion. METHOD:Thirty never-symptomatic and 81 symptomatic patients with carotid occlusion underwent baseli...

journal_title：Neurology

authors： Powers WJ,Derdeyn CP,Fritsch SM,Carpenter DA,Yundt KD,Videen TO,Grubb RL Jr

更新日期：2000-02-22 00:00:00

abstract：OBJECTIVE:Nonmotor symptoms (sleep dysfunction, sensory symptoms, autonomic dysfunction, mood disorders, and cognitive abnormalities) in Parkinson disease (PD) are a major cause of morbidity, yet are often underrecognized. This evidence-based practice parameter evaluates treatment options for the nonmotor symptoms of P...

journal_title：Neurology

authors： Zesiewicz TA,Sullivan KL,Arnulf I,Chaudhuri KR,Morgan JC,Gronseth GS,Miyasaki J,Iverson DJ,Weiner WJ,Quality Standards Subcommittee of the American Academy of Neurology.

更新日期：2010-03-16 00:00:00

abstract：OBJECTIVE:To examine the association between cognitive function and dementia with vitamin D concentration in adults. METHODS:Five databases were searched for English-language studies up to August 2010, and included all study designs with a comparative group. Cognitive function or impairment was defined by tests of glo...

journal_title：Neurology

authors： Balion C,Griffith LE,Strifler L,Henderson M,Patterson C,Heckman G,Llewellyn DJ,Raina P

更新日期：2012-09-25 00:00:00

abstract：:Fibromyalgia (FM) and transformed migraine (TM) are common chronic pain disorders. The authors estimated the prevalence of FM in 101 patients with TM, and analyzed its relationship to depression, anxiety, and insomnia. FM was diagnosed in 35.6% of cases. Patients with FM had more insomnia, were older, and had headache...

journal_title：Neurology

authors： Peres MF,Young WB,Kaup AO,Zukerman E,Silberstein SD

更新日期：2001-10-09 00:00:00