Specific genetic influences on nighttime blood pressure.

abstract：BACKGROUND:Expression of matrix metalloproteinase (MMP) has been shown in aortic dissection and aneurysms indicating increased proteolysis compared with the normal aorta. However, its role in the development of aortic root dilatation has not been studied. We therefore attempted to determine the relationship between aor...

journal_title：American journal of hypertension

authors： Karakaya O,Barutcu I,Esen AM,Dogan S,Saglam M,Karapinar H,Akgun T,Karavelioglu Y,Esen O,Ozdemir N,Turkmen S,Kaymaz C

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Left ventricular (LV) concentric geometry and hypertrophy, depressed wall mechanics, and abnormal diastolic properties have been described in the diabetic heart. However, the cardiac response to dynamic exercise in diabetic patients remains controversial. The present study assessed strain rate (SR) imaging d...

journal_title：American journal of hypertension

authors： Galderisi M,de Simone G,Innelli P,Turco A,Turco S,Capaldo B,Riccardi G,de Divitiis O

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:The renal resistive index (RI) measured using Doppler ultrasonography has been used as a diagnostic tool in the daily work-up of kidney diseases. A better understanding of its relationship with preclinical organ damage may help in determining overall cardiovascular risk in hypertensive patients. METHODS:We ...

journal_title：American journal of hypertension

authors： Doi Y,Iwashima Y,Yoshihara F,Kamide K,Takata H,Fujii T,Kubota Y,Nakamura S,Horio T,Kawano Y

更新日期：2012-12-01 00:00:00

abstract：:This article examines the results of the Joint National Committee's Fifth Report on the treatment of hypertension (JNC-V), especially regarding the economic arguments put forth therein. Economics are a poor basis for treatment decisions, as the cheapest therapies may not be the best for any given patient. Broad treatm...

journal_title：American journal of hypertension

authors： Ménard J

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:Azilsartan medoxomil (AZL-M), an angiotensin II receptor blocker, demonstrates antihypertensive and organ protective effects in hypertension. We investigated the efficacy of AZL-M to ameliorate metabolic syndrome and kidney damage associated with type 2 diabetes using Zucker diabetic fatty (ZDF) rats. METHO...

journal_title：American journal of hypertension

authors： Hye Khan MA,Neckář J,Haines J,Imig JD

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:It is unknown whether the physiological impact of a given blood pressure (BP) varies by body size. We explored interactions between higher vs. lower systolic BP (SBP) targets and anthropometric measures (body mass index (BMI), body surface area (BSA), height, weight) and recurrent stroke and death in the Sec...

journal_title：American journal of hypertension

authors： Field TS,McClure LA,White CL,Pergola PE,Hart RG,Benavente OR,Hill MD,SPS3 Investigators.

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:The efficacy and safety of angiotensin receptor blockers (ARBs) in the older population is unclear. OBJECTIVES:To determine the efficacy and safety of ARBs in older patients. METHODS:Randomized trials that compared ARBs to control and reported clinical outcomes in patients with a mean age of 65 years or ol...

journal_title：American journal of hypertension

authors： Elgendy IY,Huo T,Chik V,Pepine CJ,Bavry AA

更新日期：2015-05-01 00:00:00

abstract：:A prospective randomized, double-blind, double-dummy study investigated the effects of two angiotensin converting enzyme (ACE) inhibitors on urinary albumin excretion in nondiabetic patients with mild to moderate essential hypertension. At the end of a 4-week placebo run-in period, 36 patients were randomly allocated ...

journal_title：American journal of hypertension

authors： Puig JG,Mateos FA,Ramos TH,Lavilla MP,Capitán MC,Gil A

更新日期：1994-01-01 00:00:00

abstract：:The role of renal sympathetic nerve activity (RSNA) in the maintenance phase of essential hypertension has not yet been clearly defined. Renal function and mean arterial pressure (MAP) were studied in four Yucatan miniature swine (YMS) with established DOCA hypertension prior to and for 3 weeks after surgical renal de...

journal_title：American journal of hypertension

authors： O'Hagan KP,Thomas GD,Zambraski EJ

更新日期：1990-01-01 00:00:00

abstract：:Congenital protein C deficiency is now widely recognized as a genetic risk for venous thrombosis. However, it remains uncertain whether this condition also confers risk for arterial thrombosis. We evaluated the association of congenital protein C deficiency with hypertension and silent cerebrovascular disease using br...

journal_title：American journal of hypertension

authors： Kario K,Sakata T,Higashikawa M,Katayama Y,Hoshide S,Shimada K,Miyata T

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:Recently, some investigators have shown that telmisartan, an angiotensin II (Ang II)-receptor blocker (ARB), is a partial agonist of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma). We investigate whether telmisartan improves cardiovascular remodeling associated with the production of endot...

journal_title：American journal of hypertension

authors： Kobayashi N,Ohno T,Yoshida K,Fukushima H,Mamada Y,Nomura M,Hirata H,Machida Y,Shinoda M,Suzuki N,Matsuoka H

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:This study was conducted to evaluate (i) the effect of nebivolol, a selective beta1-adrenergic receptor antagonist, on plasma concentration of asymmetric dimethylarginine (ADMA) and on flow-mediated dilation (FMD) in essential hypertensive patients; (ii) the effect of serum derived from the treated hypertens...

journal_title：American journal of hypertension

authors： Pasini AF,Garbin U,Stranieri C,Boccioletti V,Mozzini C,Manfro S,Pasini A,Cominacini M,Cominacini L

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Increased short-term blood pressure (BP) variability (BPV) in hemodialysis is associated with increased cardiovascular and all-cause mortality. Studies on the impact of BP-lowering interventions on BPV are scarce. This study examined the effect of dry-weight reduction with a lung ultrasound-guided strategy o...

journal_title：American journal of hypertension

authors： Loutradis C,Sarafidis PA,Theodorakopoulou M,Ekart R,Alexandrou ME,Pyrgidis N,Angeloudi E,Tzanis G,Toumpourleka M,Papadopoulou D,Mallamaci F,Zoccali C,Papagianni A

更新日期：2019-07-17 00:00:00

abstract：BACKGROUND:Evaluating effect of acute or chronic use of antihypertensives on risk of falls in older adults. METHODS:Data sources: Systematic search of primary research articles in CINAHL, Cochrane, EBM, EMBASE, and MEDLINE databases from January 1 2007 to June 1 2017. Study selection: Research studies of cohort, case-...

journal_title：American journal of hypertension

authors： Kahlaee HR,Latt MD,Schneider CR

更新日期：2018-03-10 00:00:00

abstract：BACKGROUND:Patients often exhibit higher blood pressure (BP) readings in the doctor's office, a phenomenon known as the white coat effect. This study examines the presence of a physician in the examining room as a possible factor in provoking a white coat effect. METHODS:Blood pressure measurements taken by an automat...

journal_title：American journal of hypertension

authors： Myers MG,Valdivieso MA

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:Obesity is one of the main determinants of blood pressure. The aim of this study was to evaluate and quantify the relations between the different anthropometric indices and blood pressure (BP) stratified by gender. METHODS:Cross-sectional analyses were performed using data from 2,105 adults from the ESTEBAN...

journal_title：American journal of hypertension

authors： Vallée A,Perrine AL,Deschamps V,Blacher J,Olié V

更新日期：2019-09-24 00:00:00

abstract：:Angiotensin receptors became relatively easy to study when radioactive derivatives of the peptide were synthesized for radioimmunoassays. Binding assays in vitro led to the discovery of receptors in many tissues different from those involved in the classic actions of angiotensin. The physiologic significance of recept...

journal_title：American journal of hypertension

authors： Goodfriend TL

更新日期：2000-04-01 00:00:00

abstract：BACKGROUND:The brain is perfused at high-volume flow throughout systole and diastole. We explored the association of blood flow in the middle cerebral artery (MCA) with the pulsatile components of blood pressure in the systemic circulation and indices of arterial stiffness. METHODS:We enrolled 334 untreated subjects (...

journal_title：American journal of hypertension

authors： Xu TY,Staessen JA,Wei FF,Xu J,Li FH,Fan WX,Gao PJ,Wang JG,Li Y

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Ischemia-induced reactive hyperemia (RH) is mediated by various factors including release of nitric oxide (NO). The contribution of NO to RH equals the extent of L-NMMA-dependent reduction of forearm blood flow (FBF). Because the optimal duration and location of ischemia that provokes maximum NO activation i...

journal_title：American journal of hypertension

authors： Raff U,Ott C,John S,Schmidt BM,Fleischmann EH,Schmieder RE

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:We previously showed that the infusion of tumor necrosis factor alpha (TNF-alpha) induces hypertension and vascular dysfunction in late pregnant but not virgin rats. In the present study, we tested the hypothesis that levels of ovarian hormones to mimic pregnancy are required for TNF-alpha-induced changes in...

journal_title：American journal of hypertension

authors： LaMarca BD,Chandler DL,Grubbs L,Bain J,McLemore GR Jr,Granger JP,Ryan MJ

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:In the United States, roughly one-third of adults have hypertension; another third have prehypertension. The prevalence of hypertension in deaf American Sign Language (ASL) users is unknown. We address this gap through a descriptive study for the prevalence of hypertension in the American Deaf community and ...

journal_title：American journal of hypertension

authors： Simons AN,Moreland CJ,Kushalnagar P

更新日期：2018-10-15 00:00:00

abstract：BACKGROUND:We hypothesized that high-dose active vitamin D therapy in the form of alphacalcidol (α-calcidol), used to treat secondary hyperparathyroidism in chronic kidney disease, could lead to vascular calcification and accelerated progression of aortic stiffness. METHODS:We conducted an observational study in 85 pa...

journal_title：American journal of hypertension

authors： Fortier C,Mac-Way F,De Serres SA,Marquis K,Douville P,Desmeules S,Larivière R,Agharazii M

更新日期：2014-11-01 00:00:00

abstract：:The aim of this study was to assess whether an interaction exists between the renin-angiotensin system and the sympathetic nervous system at the level of the adrenal medulla during insulin-induced hypoglycemia in normal humans. Seventeen healthy volunteers were studied in a randomized, single-dose, double-blind, cross...

journal_title：American journal of hypertension

authors： Madsen BK,Hølmer P,Ibsen H,Christensen NJ

更新日期：1992-06-01 00:00:00

abstract：:Apart from the well-known role of hypertension in cerebrovascular disease, visit-to-visit blood pressure (BP) variability is emerging as an independent risk factor for stroke. Although the underlying mechanism is not fully understood, artery remodeling is thought to be closely involved in the relationship between visi...

journal_title：American journal of hypertension

authors： Nagai M,Kario K

更新日期：2013-12-01 00:00:00

abstract：:The present study evaluated the effects of miconazole, a selective inhibitor of epoxygenase activity, on renal hemodynamics and the pressure-natriuresis response of saline-drinking, uninephrectomized Lyon hypertensive (LH) and Lyon low blood pressure (LL) rats. Infusion of miconazole (final concentration, 1 micromol/L...

journal_title：American journal of hypertension

authors： Messer-Létienne I,Bernard N,Roman RJ,Sassard J,Benzoni D

更新日期：1999-04-01 00:00:00

abstract：:We previously showed that the lymphocyte proliferation response was significantly suppressed in spontaneously hypertensive rats (SHR) and that this depressed response was due to excessive production of nitric oxide (NO) in macrophages and vascular smooth muscle cells (VSMC). Whether lymphocyte depression and activatio...

journal_title：American journal of hypertension

authors： Xiao J,Pang PK

更新日期：1996-04-01 00:00:00

abstract：:This study examined the effects of alterations in salt-intake on blood pressure (BP) in rats chronically treated intravenously with or without the nitric oxide synthase (NOS) inhibitor N(G)-nitro-L-arginine methyl ester (L-NAME) (8.6 mg/kg/day). The changes in mean arterial pressure (MAP), the renal cortical and medul...

journal_title：American journal of hypertension

authors： Nakanishi K,Hara N,Nagai Y

更新日期：2002-02-01 00:00:00

abstract：:Angiotensin-converting enzyme inhibitors (ACEIs), introduced in clinical practice in 1980, are a relatively new class of drugs. They have been useful in the treatment of hypertension, where they are effective monotherapy in 40% to 50% of the patients and in combination therapy in up to 90%. They are also useful in the...

journal_title：American journal of hypertension

authors： Kostis JB

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:The "nondipping" pattern (NDP) of blood pressure, characterized by the absence of the reduction in blood pressure (BP) that typically takes place during the night time, has been associated with elevated cardiovascular morbidity, including stroke, myocardial infarction, and sudden cardiac-related death. In va...

journal_title：American journal of hypertension

authors： Myredal A,Friberg P,Johansson M

更新日期：2010-03-01 00:00:00

abstract：:Hypertension is a major risk factor for cardiovascular disease, and small reductions in blood pressure can have a substantial impact on outcome. Effective control of hypertension per se is important in reducing morbidity and mortality, but there is growing evidence that the class of drug used in treatment may affect p...

journal_title：American journal of hypertension

authors： Oparil S

更新日期：2002-01-01 00:00:00