Mechanisms and possible causes of Alzheimer's disease.

abstract：:Type 2 diabetes, which is increasing in prevalence, is a multifaceted disease that presents a challenge to the primary care physician. In this article, Drs Flemmer and Vinik review the significant findings of several important clinical trials and present a method of comprehensive staged management to improve the quali...

journal_title：Postgraduate medicine

authors： Flemmer MC,Vinik AI

更新日期：2000-05-01 00:00:00

abstract：:What clinical circumstances call for aggressive treatment of jaundice in newborns? Is cessation of breast-feeding necessary to help bring down the high bilirubin concentration? When should phototherapy be started--and stopped? The authors address these and other questions in this thorough guide to differential diagnos...

journal_title：Postgraduate medicine

authors： Lasker MR,Holzman IR

更新日期：1996-03-01 00:00:00

abstract：:Obesity is currently a worldwide epidemic, and will likely only increase in prevalence in the coming years. The incidence of the metabolic syndrome (MetS) seems to be paralleling obesity. The MetS is strongly linked to insulin resistance, abdominal obesity, diabetes mellitus, and dyslipidemia. Nonalcoholic fatty liver...

journal_title：Postgraduate medicine

authors： Boppidi H,Daram SR

更新日期：2008-07-31 00:00:00

abstract：BACKGROUND:Point-of-care testing (POCT) is widely used to measure blood glucose levels in people with diabetes, although its use in measuring glycated hemoglobin (HbA1c) levels is less common, perhaps due to perceived performance issues and access to the technology. METHODS:Forty blood samples were analyzed in duplica...

journal_title：Postgraduate medicine

authors： Knaebel J,Irvin BR,Xie CZ

更新日期：2013-05-01 00:00:00

abstract：:A high index of suspicion and careful application of diagnostic methods are essential for accurate diagnosis of parasitic bowel diseases. The varied clinical spectrum of giardiasis, amebiasis, and strongyloidiasis emphasizes the need to consider these pathogens when patients present with gastrointestinal complaints. G...

journal_title：Postgraduate medicine

authors： Burns TW

更新日期：1982-05-01 00:00:00

abstract：:Inflammatory bowel disease is a conglomeration of disorders of unclear etiology and pathogenesis. Confirming the diagnosis of active disease may be difficult but is critical to judicious therapy. Sulfasalazine (Azulfidine) and its newer derivatives mesalamine (Asacol, Rowasa) and olsalazine sodium (Dipentum) are used ...

journal_title：Postgraduate medicine

authors： Butt JH

更新日期：1992-11-01 00:00:00

abstract：:While there is evidence for cardiac arrhythmias associated with macrolide and fluoroquinolone antibiotics, there is still debate among health care providers as to whether this risk of arrhythmia is overstated. A joint panel of the US Food and Drug Administration suggested that macrolide and fluoroquinolone labels need...

journal_title：Postgraduate medicine

authors： Cornett E,Novitch MB,Kaye AD,Pann CA,Bangalore HS,Allred G,Bral M,Jhita PK,Kaye AM

更新日期：2017-09-01 00:00:00

abstract：:Preview Severe metabolic complications of diabetes mellitus are a common cause of morbidity and death in both type I and type II disease. The distinctions between diabetic ketoacidosis and hyperosmolar nonketotic state are clearly defined, and accurate recognition is important for proper treatment. This article focuse...

journal_title：Postgraduate medicine

authors： Gonzalez-Campoy JM,Robertson RP

更新日期：1996-06-01 00:00:00

abstract：:Thymomas may be discovered during routine evaluation, through reported symptoms, or increasingly, during evaluation for myasthenia gravis. Histologic details of these tumors have little bearing on prognosis or evaluation of malignant potential. Malignancy is determined by evidence of invasion through the tumor capsule...

journal_title：Postgraduate medicine

authors： Cohen DJ

更新日期：1986-03-01 00:00:00

abstract：:Preview New information emerges almost weekly about the relative importance of one factor or another in the development of coronary artery disease. Yet controversies continue over which factor deserves the most emphasis. Dr Elliott presents a broad and, at times, humorous look at research into cardiovascular risk fact...

journal_title：Postgraduate medicine

authors： Elliott WJ

更新日期：1994-09-01 00:00:00

abstract：:Combination therapy is a cost-effective and rational approach to treatment of severe hypertension and of mild to moderate hypertension that is refractory to monotherapy. The method has several advantages, most notably improved tolerability and enhanced antihypertensive efficacy. Long-term prospective studies are neede...

journal_title：Postgraduate medicine

authors： Houston MC

更新日期：1998-09-01 00:00:00

abstract：:Syndromes of delusional misidentification consist of disordered familiarity and have been reported in diverse diagnoses, including Parkinson's disease. Although the most common delusional misidentification is Capgras syndrome, in which the sufferer believes a familiar person has been replaced by an identical imposter,...

journal_title：Postgraduate medicine

authors： Hermanowicz N

更新日期：2018-03-01 00:00:00

abstract：:Review of: Wallentin L, Becker RC, Budaj A, et al. Ticagrelor versus clopidogrel in patients with acute coronary syndromes. N Eng J Med 2009; 361(11): 1045-1057. For acute coronary syndrome (ACS), a dual antiplatelet regimen comprised of treatment with aspirin and either P2Y12 adenosine diphosphate receptor antagonist...

journal_title：Postgraduate medicine

authors： Amico F,Amico A,Mazzoni J,Moshiyakhov M,Tamparo W

更新日期：2016-01-01 00:00:00

abstract：:Coma is a common, life-threatening medical problem encountered by primary care physicians. The principles of emergency management mandate that adequate oxygenation, blood flow, and supplementation with thiamine and glucose be given to the brain before a thorough diagnostic evaluation is undertaken. Knowledge of the us...

journal_title：Postgraduate medicine

authors： Alguire PC

更新日期：1990-05-01 00:00:00

abstract：:Tests to measure the volume of gastric contents are necessary to determine the nature of a gastric emptying disorder. The conditions that can affect gastric emptying are as varied as peptic ulcer disease, achlorhydria, viral and bacterial infections of the stomach, diabetes, scleroderma, anorexia nervosa, and CNS lesi...

journal_title：Postgraduate medicine

authors： McCallum RW

更新日期：1987-02-15 00:00:00

abstract：:Physicians need to be aware that women and mothers are capable of sexually abusing children and need to watch for signs that a mother may be at risk for perpetrating abuse or that a child may have been abused. Posttraumatic stress disorder, attention-deficit hyperactivity disorder, secondary enuresis and encopresis, n...

journal_title：Postgraduate medicine

authors： Elliott AJ,Peterson LW

更新日期：1993-07-01 00:00:00

abstract：:Diagnostic paracentesis with ascitic fluid analysis is critical to the accurate diagnosis and management of ascites. Recent advances have improved the evaluation of ascitic fluid, among them the serum-ascites albumin difference for discriminating between ascites caused by liver disease and ascites due to malignancy. T...

journal_title：Postgraduate medicine

authors： Marshall JB

更新日期：1988-06-01 00:00:00

abstract：:Electroconvulsive therapy is controversial and readily arouses the passions of both its supporters and detractors. In this article, Dr Schoen, an internist, discusses various aspects of this 50-year-old technique, including risks, contraindications, and physiologic effects. ...

journal_title：Postgraduate medicine

authors： Schoen RE

更新日期：1990-05-01 00:00:00

abstract：:Persistent hoarseness in a patient should always alert the physician to the possibility of laryngeal carcinoma. Prompt visualization of the larynx is essential, particularly in high-risk patients over 40 years of age without a history of upper respiratory infection. Mirror examination (indirect laryngoscopy) is the us...

journal_title：Postgraduate medicine

authors： Johnson JT,Newman RK,Olson JE

更新日期：1980-05-01 00:00:00

abstract：:The diagnostic survey of the infertile couple usually takes about three months. After semen analysis, the husband is referred for general and urologic examination. The wife is given a general physical and pelvic examination and returns during the next two months for ovulation studies. Tubal patency tests are also perf...

journal_title：Postgraduate medicine

authors： Cohen MR

更新日期：1977-10-01 00:00:00

abstract：:Infective endocarditis refers to infection of the endocardium or heart valves by microbes, resulting in tissue destruction. Clinical presentation is quite variable, and a high level of suspicion is essential for recognition. Diagnosis is dependent on identification of the causative agent in blood cultures. Cultures th...

journal_title：Postgraduate medicine

authors： Nunley DL,Perlman PE

更新日期：1993-04-01 00:00:00

abstract：:Management of pain syndromes clearly requires a multidimensional approach and involves social, psychologic, and somatic factors. At the Behavioral Medicine/Pain Therapy Center of Jewish Hospital, St Louis, most patients significantly increase social and physical activity using the combined approach outlined. A majorit...

journal_title：Postgraduate medicine

authors： Bakris GL,Zorumski CF

更新日期：1983-05-01 00:00:00

abstract：:Many patients who present with acute or chronic diarrhea do not have an important organic disease. Most have functional diarrhea. The history, clinical examination, and initial laboratory studies should lead to a provisional diagnosis with respect to organic or functional origin and help define whether the disease aff...

journal_title：Postgraduate medicine

authors： Bruckstein AH

更新日期：1989-12-01 00:00:00

abstract：:Symptomatic treatment of transient insomnias is advisable, for without treatment these sleep disorders may become persistent. The drugs of choice are the benzodiazepine hypnotics, which have minimal side effects when used for short periods in properly selected patients. The three such drugs currently available in the ...

journal_title：Postgraduate medicine

authors： Malcolm R,Gross JA

更新日期：1984-07-01 00:00:00

abstract：:Aspiration results from abnormal structure or from dysfunction during the oral, pharyngeal, or esophageal stage of deglutition. Chemically induced inflammation of the lungs and obstruction of the airways may ensue. Feeding and swallowing problems may occur at any age, but they are particularly prevalent in the elderly...

journal_title：Postgraduate medicine

authors： Khawaja IT,Buffa SD,Brandstetter RD

更新日期：1992-07-01 00:00:00

abstract：:Difficult or painful coitus is a symptom, not a pathologic entity. It may be caused by a congenital anomaly, an organic lesion, or a functional disorder of the vulva or vagina, or it may be psychic in origin. Although its cause can usually be determined relatively easily, a conditioned reflex created by a preexisting ...

journal_title：Postgraduate medicine

authors： Huffman JW

更新日期：1983-02-01 00:00:00

abstract：:Solitary pulmonary nodules are usually identified on routine chest radiographs in asymptomatic patients. Most nodules have a benign cause, but bronchogenic carcinoma, metastases, and other malignant processes are important causes as well and must be excluded in differential diagnosis. Plain chest radiography, computed...

journal_title：Postgraduate medicine

authors： Dholakia S,Rappaport DC

更新日期：1996-02-01 00:00:00

abstract：:Treatment of asymptomatic diverticulosis is geared to the prevention of constipation, with vigilance for possible signs of complications. A bulky stool decreases colonic intraluminal pressures, probably lessening pain and the chance of development of new diverticula. Increased stool weight may be achieved by the addit...

journal_title：Postgraduate medicine

authors： Herrera AF

更新日期：1976-12-01 00:00:00

abstract：:Preview Early diagnosis of sickle cell disease enables physicians to initiate prompt treatment and provide appropriate education and counseling for patients and their families. In this article, Dr Burdick reviews the management of major complications of the disorder, discusses the psychosocial impact, and examines the...

journal_title：Postgraduate medicine

authors： Burdick E

更新日期：1994-12-01 00:00:00

abstract：:Flooding of the lungs occurs routinely in drowning victims. The cause of death in 90% of them is hypoxemia caused by water in the lungs. Mouth-to-mouth ventilation is ineffective until the water is removed. The Heimlich maneuver expels aspirated water, vomitus, debris, and other foreign matter. In treating near-drowni...

journal_title：Postgraduate medicine

authors： Heimlich HJ,Patrick EA

更新日期：1988-08-01 00:00:00